Friday, July 10, 2026
🇺🇸 FDA

Intelligence · Clinical pipeline

Phase II Pipeline Programs

Proof-of-concept and dose-finding clinical programs in Phase II development.

Programs 7,238
Sponsors 1,771
Drugs 4,798

Quick answer

NovaPharmaNews tracks 7,238 phase ii pharmaceutical pipeline programs from ClinicalTrials.gov. Proof-of-concept and dose-finding clinical programs in Phase II development.

Top sponsors

Pipeline programs

Page 4 of 151

  1. 2215-CL-0603

    Astellas Pharma GmbH

    FMS-like Tyrosine Kinase 3 (FLT3)/Internal Tandem Duplication (ITD) Positive Relapsed or Refractory Acute Myeloid Leukemia (AML)

    phase 2 small molecule active

    1 trial

  2. 222291

    GlaxoSmithKline

    Liver Diseases, Alcoholic

    phase 2 other active

    1 trial

  3. 222638

    ViiV Healthcare Pty Ltd

    HIV Infections

    phase 2 small molecule active

    1 trial

  4. 222730

    GlaxoSmithKline

    Ovarian Neoplasms

    phase 2 other active

    1 trial

  5. 222892

    GlaxoSmithKline

    MMRp/ MSS colon cancer

    phase 2 small molecule active

    1 trial

  6. 223050

    GlaxoSmithKline

    Neoplasms, Prostate

    phase 2 other active

    1 trial

  7. 223559

    GlaxoSmithKline

    Tumours, Gynecological

    phase 2 small molecule active

    1 trial

  8. 223584

    GlaxoSmithKline

    Myelodysplastic Syndrome

    phase 2 other active

    1 trial

  9. 223646

    GlaxoSmithKline

    Alzheimer's Disease

    phase 2 other active

    1 trial

  10. 223675

    GlaxoSmithKline

    Gastrointestinal Neoplasms

    phase 2 other active

    1 trial

  11. 224035

    GlaxoSmithKline

    Neoplasms, Colorectal

    phase 2 other active

    1 trial

  12. 224083

    GlaxoSmithKline

    Respiratory Syncytial Virus Infections

    phase 2 small molecule active

    1 trial

  13. 224317

    GlaxoSmithKline

    Relapsed or Refractory Multiple Myeloma

    phase 2 small molecule active

    1 trial

  14. 225Ac-J591

    United Therapeutics Europe Ltd

    Prostate Cancer

    phase 2 small molecule active

    2 trials

  15. 225Ac-LNC1011

    The First People's Hospital of Lianyungang

    Prostate Cancer

    phase 2 small molecule active

    1 trial

  16. 22752

    Bayer AG

    HER2 mutation, Advanced solid tumors

    phase 2 small molecule active

    1 trial

  17. 22774

    Disc Medicine

    Chronic Kidney Disease

    phase 2 small molecule active

    1 trial

  18. 22U-0320

    Disc Medicine

    Fahr's disease, Fahr's syndrome

    phase 2 small molecule active

    1 trial

  19. 23U-0160

    Disc Medicine

    Diffuse Midline Glioma, H3K27-altered

    phase 2 small molecule active

    1 trial

  20. 2402T1432

    Shionogi B.V.

    Respiratory Syncytial Virus

    phase 2 other active

    1 trial

  21. 250 mg LX1033 tablets

    LEXICON PHARMACEUTICALS, INC.

    Irritable Bowel Syndrome

    phase 2 small molecule completed

    1 trial

  22. 283PD201

    Biogen

    Parkinson's Disease

    phase 2 small molecule active

    1 trial

  23. 299AR201

    Biogen

    Treatment of Late Isolated Microvascular Inflammation in Recipients of Kidney Transplants

    phase 2 small molecule active

    1 trial

  24. 2G-MSC-GVHD

    The George Institute

    Patients who have developed acute GVHD refractory to corticosteroids and ruxolitinib or that are not eligible to receive ruxolitinib

    phase 2 small molecule active

    1 trial

  25. 2HPβCD

    ZyVersa Therapeutics

    Diabetic Kidney Disease

    phase 2 small molecule terminated

    1 trial

  26. 2X-121

    Allarity Therapeutics

    Advanced Ovarian Cancer

    phase 2 small molecule active

    1 trial

  27. 2mg Buprenex and 380mg Vivitrol

    United Therapeutics Europe Ltd

    Post Traumatic Stress Disorder

    phase 2 small molecule terminated

    1 trial

  28. 3,4-Methylenedioxymethamphetamine (MDMA)

    United Therapeutics Europe Ltd

    Post Traumatic Stress Disorder

    phase 2 small molecule active

    1 trial

  29. 3-V Bioscience-2640

    Sagimet Biosciences

    Metabolic Syndrome

    phase 2 small molecule completed

    1 trial

  30. 30% Nitrous oxide

    BRIGHT MINDS BIOSCIENCES INC.

    Alcohol-Related Disorders

    phase 2 small molecule completed

    1 trial

  31. 300148

    GlaxoSmithKline

    Neoplasms

    phase 2 small molecule active

    1 trial

  32. 300336

    GlaxoSmithKline

    Influenza, Human

    phase 2 small molecule active

    1 trial

  33. 300356

    GlaxoSmithKline

    Influenza, Human

    phase 2 small molecule active

    1 trial

  34. 30mg PRAX-628

    Chongqing Precision Biotech Co., Ltd

    Focal Onset Seizure

    phase 2 small molecule active

    1 trial

  35. 3124001

    Orion Laboratories Pty.

    Metastatic castration-resistant prostate cancer.

    phase 2 small molecule active

    1 trial

  36. 3133003

    Orion Laboratories Pty.

    Chronic Pain due to Ostheoarthritis of the knee

    phase 2 small molecule active

    1 trial

  37. 3133004

    Orion Laboratories Pty.

    CHRONIC PAIN DUE TO DIABETIC PERIPHERAL NEUROPATHY

    phase 2 small molecule active

    1 trial

  38. 3134003

    Orion Laboratories Pty.

    Neoplasms benign malignant and unspecified (incl. cysts and polyps)

    phase 2 small molecule active

    1 trial

  39. 3D hypoxia-preconditioned UC-MSC group

    The First People's Hospital of Lianyungang

    Severe Aplastic Anemia (SAA)

    phase 2 small molecule active

    1 trial

  40. 4-L-[131I]iodo-phenylalanine (131I-IPA)

    Telix Innovations

    Glioblastoma Multiforme

    phase 2 other completed

    1 trial

  41. 40 mg glatiramer acetate

    Teva Pharma GmbH

    Amyotrophic Lateral Sclerosis

    phase 2 small molecule completed

    1 trial

  42. 400 U EV71 vaccine with adjuvant

    Sinovac Research and Development Co.,

    Infection, Viral, Enterovirus

    phase 2 mab terminated

    1 trial

  43. 400 microgrammes GSK961081

    Theravance Biopharma Ireland Umited

    Pulmonary Disease, Chronic Obstructive

    phase 2 small molecule completed

    1 trial

  44. 400 µg of MBX 2109 once-weekly by subcutaneous injection

    MBX Biosciences

    Hypoparathyroidism

    phase 2 small molecule active

    1 trial

  45. 408-C-1402

    Lacuna Pharma Pty Ltd

    Friedreich's ataxia

    phase 2 small molecule active

    1 trial

  46. 413ABM

    BRIGHT MINDS BIOSCIENCES INC.

    MALARIA

    phase 2 other completed

    1 trial

  47. 42 mg transdermal nicotine replacement

    BRIGHT MINDS BIOSCIENCES INC.

    Tobacco Use Disorder

    phase 2 small molecule completed

    1 trial

  48. 42756493BLC2001

    Janssen-Cilag International N.V.

    Urothelial cancer

    phase 2 small molecule active

    1 trial

Frequently asked questions

How many Phase II pipeline programs are in the directory?

7,238 published programs match this development stage in our ClinicalTrials.gov index.

What defines this pipeline stage?

Phase and status reflect ClinicalTrials.gov registry fields at last sync. See our clinical trial phases reference for methodology.

Drug approvals, clinical trials, M&A, event intelligence, and company updates — weekly.

Customize topics & region
Topics
Region

No spam. Unsubscribe anytime. See our privacy policy.