Saturday, July 11, 2026

Intelligence · Clinical pipeline

Phase II Pipeline Programs

Proof-of-concept and dose-finding clinical programs in Phase II development.

Programs 7,238
Sponsors 1,771
Drugs 4,798

Quick answer

NovaPharmaNews tracks 7,238 phase ii pharmaceutical pipeline programs from ClinicalTrials.gov. Proof-of-concept and dose-finding clinical programs in Phase II development.

Top sponsors

Pipeline programs

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  1. CX-8998

    Jazz Pharmaceuticals Ireland Limited

    Essential Tremor

    phase 2 small molecule completed

    1 trial
  2. CX-8998

    Jazz Pharmaceuticals Ireland Limited

    Epilepsy

    phase 2 small molecule completed

    1 trial
  3. CX11202

    Lacuna Pharma Pty Ltd

    Type 2 Diabetes Mellitus

    phase 2 small molecule active

    1 trial
  4. CX501

    Takeda

    EPIDERMOLYSIS BULLOSA

    phase 2 small molecule completed

    1 trial
  5. CXXB750A12201

    Novartis Pharmaceuticals

    Heart Failure

    phase 2 small molecule active

    1 trial
  6. CY 6022

    Cytokinetics (Ireland) Limited

    Symptomatic hypertrophic cardiomyopathy (HCM)

    phase 2 small molecule active

    1 trial
  7. CYB003

    BRIGHT MINDS BIOSCIENCES INC.

    Major Depressive Disorder

    phase 2 small molecule completed

    1 trial
  8. CYCAD-1(D8470C00001)

    AstraZeneca AB

    Patients with ER+ HER2- advanced breast cancer and patients with high-grade serious ovarian cancer (HGSOC)

    phase 2 small molecule active

    1 trial
  9. CYCLOPHOSPHAMIDE for Inoperable locally advanced or…

    Istituto Gentili S.r.l.

    Inoperable locally advanced or metastatic TNBC patients, previously treated with anti-PD-L1/PD1- regimens

    phase 2 small molecule active

    1 trial
  10. CYD Dengue Vaccine

    United Therapeutics Europe Ltd

    Dengue

    phase 2 mab completed

    1 trial
  11. CYSTAGON 150 mg hard capsules

    The George Institute

    Infectious diseases of respiratory system (COVID-19)

    phase 2 small molecule active

    1 trial
  12. CYSTAGON 50 mg hard capsules

    The George Institute

    Pulmonary Tuberculosis

    phase 2 small molecule active

    1 trial
  13. CYTB323A12101

    Novartis Pharmaceuticals

    High-Risk large B-Cell lymphoma, Chronic lymphocytic leukemia/Small lymphocytic lymphoma, Diffuse large B-Cell lymphoma, Acute lymphoblastic leukemia

    phase 2 small molecule active

    1 trial
  14. CYTB323G12101

    Novartis Pharmaceuticals

    Systemic Lupus Erythematosus., Lupus Nephritis

    phase 2 small molecule active

    1 trial
  15. CYTB323J12201

    Novartis Pharmaceuticals

    Active, refractory systemic lupus erythematosus (SLE), and active, refractory lupus nephritis (LN)

    phase 2 small molecule active

    1 trial
  16. CYTB323K12201

    Novartis Pharmaceuticals

    Diffuse cutaneous systemic sclerosis (dcSSc)

    phase 2 small molecule active

    1 trial
  17. CYTB323L12201

    Novartis Pharmaceuticals

    Severe refractory idiopathic inflammatory myopathies (IIM)

    phase 2 small molecule active

    1 trial
  18. CYTB323M12101B

    Novartis Pharmaceuticals

    Difficult to treat rheumatoid arthritis, Severe, refractory Sjogren’s disease with organ involvement

    phase 2 small molecule active

    1 trial
  19. CYTB323N12101

    Novartis Pharmaceuticals

    Relapsing Multiple Sclerosis

    phase 2 small molecule active

    1 trial
  20. CYTB323O12101

    Novartis Pharmaceuticals

    Treatment-resistant generalized Myasthenia Gravis

    phase 2 small molecule active

    1 trial
  21. CYTB323R12101

    Novartis Pharmaceuticals

    Non-active Progressive Multiple Sclerosis (PMS)

    phase 2 small molecule active

    1 trial
  22. CaPre (TM)

    Grace Therapeutics

    Hypertriglyceridemia

    phase 2 small molecule completed

    1 trial
  23. Cabergoline 1 MG

    Monte Rosa Therapeutics

    Lactation Suppressed

    phase 2 small molecule completed

    1 trial
  24. Cabozantinib

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Hepatocellular Carcinoma (HCC)

    phase 2 small molecule active

    1 trial
  25. Cabozantinib

    Takeda

    Advanced Renal Cell Carcinoma

    phase 2 small molecule completed

    1 trial
  26. Cabozantinib

    Takeda

    Advanced Hepatocellular Carcinoma

    phase 2 small molecule completed

    1 trial
  27. Cabozantinib Ipsen 20 mg film-coated tablets

    Disc Medicine

    Renal cell carcinom

    phase 2 small molecule active

    1 trial
  28. Cadonilimab

    Second Affiliated Hospital of Soochow University

    Immunotherapy

    phase 2 small molecule active

    1 trial
  29. Cadonilimab

    The First People's Hospital of Lianyungang

    Recurrent or Metastatic Esophageal Squamous Cell Carcinoma

    phase 2 small molecule active

    1 trial
  30. Cadonilimab

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Cervical Cancer

    phase 2 small molecule active

    1 trial
  31. Cadonilimab

    The First People's Hospital of Lianyungang

    Lung Cancer

    phase 2 small molecule active

    1 trial
  32. Cadonilimab

    The First People's Hospital of Lianyungang

    Immunotherapy

    phase 2 small molecule active

    1 trial
  33. Caffeine 150 MG

    BRIGHT MINDS BIOSCIENCES INC.

    Cocaine Dependence

    phase 2 small molecule completed

    1 trial
  34. Caffeine citrate

    BRIGHT MINDS BIOSCIENCES INC.

    Retinopathy of Prematurity

    phase 2 small molecule completed

    1 trial
  35. Calcio levofolinato Teva Generics polvere per...

    Fondazione Telethon ETS

    Patients with metastatic colorectal cancer (mCRC) RAS-mutant

    phase 2 small molecule active

    1 trial
  36. Calcium Gluconate

    United Therapeutics Europe Ltd

    Trauma

    phase 2 small molecule active

    1 trial
  37. Calquence 100 mg film-coated tablets

    AstraZeneca

    mantle cell lymphoma (MCL)

    phase 2 small molecule active

    1 trial
  38. Camidanlumab Tesirine

    ADC Therapeutics SA

    Relapsed Hodgkin Lymphoma

    phase 2 small molecule completed

    1 trial
  39. Camostat Mesilate

    United Therapeutics Europe Ltd

    Severe Acute Respiratory Syndrome

    phase 2 small molecule completed

    1 trial
  40. Camrelizumab

    The First People's Hospital of Lianyungang

    Gastric Cancer Stage III

    phase 2 small molecule active

    1 trial
  41. Camrelizumab

    The First People's Hospital of Lianyungang

    Lung Cancer, Nonsmall Cell

    phase 2 small molecule active

    1 trial
  42. Camrelizumab

    The First People's Hospital of Lianyungang

    Locally Advanced or Metastatic Gastric Adenocarcinoma

    phase 2 small molecule active

    1 trial
  43. Camrelizumab

    The First People's Hospital of Lianyungang

    Melanoma

    phase 2 small molecule active

    1 trial
  44. Camrelizumab

    The First People's Hospital of Lianyungang

    Lung Neoplasms

    phase 2 small molecule active

    1 trial
  45. Camrelizumab

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Nasopharyngeal Carcinoma

    phase 2 small molecule active

    1 trial
  46. Camrelizumab

    The First People's Hospital of Lianyungang

    Breast Cancer

    phase 2 small molecule completed

    1 trial
  47. Camrelizumab

    The First People's Hospital of Lianyungang

    Nasopharyngeal Carcinoma

    phase 2 small molecule active

    1 trial
  48. Camrelizumab

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Adrenal Cortical Carcinoma

    phase 2 small molecule active

    1 trial

Frequently asked questions

How many Phase II pipeline programs are in the directory?

7,238 published programs match this development stage in our ClinicalTrials.gov index.

What defines this pipeline stage?

Phase and status reflect ClinicalTrials.gov registry fields at last sync. See our clinical trial phases reference for methodology.