Saturday, July 11, 2026

Intelligence · Clinical pipeline

Phase II Pipeline Programs

Proof-of-concept and dose-finding clinical programs in Phase II development.

Programs 7,238
Sponsors 1,771
Drugs 4,798

Quick answer

NovaPharmaNews tracks 7,238 phase ii pharmaceutical pipeline programs from ClinicalTrials.gov. Proof-of-concept and dose-finding clinical programs in Phase II development.

Top sponsors

Pipeline programs

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  1. COVAXIN(BBV152)

    Biotech Pharmaceutical Co.,

    Corona Virus Infection

    phase 2 mab completed

    1 trial
  2. COVID-19 Vaccine HIPRA

    Hipra Human Health S.L.

    COVID-19

    phase 2 mab completed

    1 trial
  3. COYA 302

    Coya Therapeutics

    Amyotrophic Lateral Sclerosis (ALS)

    phase 2 small molecule active

    1 trial
  4. CP101

    Finch Therapeutics Group

    Autism Spectrum Disorder

    phase 2 small molecule terminated

    1 trial
  5. CP101

    Finch Therapeutics Group

    Clostridium Difficile Infection

    phase 2 mab completed

    1 trial
  6. CPGJ602

    Sunshine Guojian Pharmaceutical (Shanghai) Co.,

    Metastatic Colorectal Cancer

    phase 2 small molecule active

    2 trials
  7. CPH-LET01

    Lacuna Pharma Pty Ltd

    Moderate and severe horizontal forehead lines.

    phase 2 small molecule active

    1 trial
  8. CPHE885B12201

    Novartis Pharmaceuticals

    Adult patients with relapsed and refractory multiple myeloma

    phase 2 small molecule active

    1 trial
  9. CPK850

    Novartis Pharmaceuticals

    Retinitis pigmentosa caused by biallelic mutations in the RLBP1 gene

    phase 2 small molecule active

    1 trial
  10. CPKC412A2218

    Novartis Pharmaceuticals

    untreated FLT3-mutated Acute Myeloid Leukemia

    phase 2 small molecule active

    1 trial
  11. CPKN605A12201

    Novartis Pharmaceuticals

    Atrial Fibrillation

    phase 2 small molecule active

    1 trial
  12. CPP-109 vigabatrin

    CATALYST PHARMACEUTICALS, INC.

    Methamphetamine Dependence

    phase 2 small molecule terminated

    1 trial
  13. CPT002/2018/PO001

    Fondazione Telethon ETS

    Metastatic colorectal cancer

    phase 2 small molecule active

    1 trial
  14. CPX-1 (Irinotecan HCl:Floxuridine) Liposome Injection

    Jazz Pharmaceuticals Ireland Limited

    Colorectal Neoplasms

    phase 2 small molecule completed

    1 trial
  15. CPX-351

    Jazz Pharmaceuticals Ireland Limited

    Leukemia, Myeloid, Acute

    phase 2 small molecule completed

    1 trial
  16. CPX-351

    Jazz Pharmaceuticals Ireland Limited

    Lymphoid Leukemia

    phase 2 small molecule completed

    1 trial
  17. CPX-351

    Jazz Pharmaceuticals Ireland Limited

    Myeloid Neoplasm

    phase 2 small molecule active

    1 trial
  18. CPX-351

    Jazz Pharmaceuticals Ireland Limited

    Acute Myeloid Leukemia (AML)

    phase 2 small molecule completed

    2 trials
  19. CPX-351

    Jazz Pharmaceuticals Ireland Limited

    Acute Myeloid Leukemia (AML) in Remission

    phase 2 small molecule active

    1 trial
  20. CPX-351

    Jazz Pharmaceuticals Ireland Limited

    Acute Myeloid Leukemia

    phase 2 small molecule completed

    7 trials
  21. CQUC398A12201

    Novartis Pharmaceuticals

    Knee osteoarthritis

    phase 2 small molecule active

    1 trial
  22. CQVM149C2201

    Novartis Pharmaceuticals

    Asthma

    phase 2 small molecule active

    1 trial
  23. CR-001

    CRESCENT BIOPHARMA, INC.

    Locally Advanced / Metastatic Solid Tumors

    phase 2 small molecule active

    1 trial
  24. CR6086-1-04

    Alphapharm Pty Ltd

    Pretreated mismatch-repair-proficient and microsatellite stable metastatic colorectal cancer, and other metastatic GI cancers

    phase 2 small molecule active

    1 trial
  25. CRAFT-T

    BRIGHT MINDS BIOSCIENCES INC.

    Heroin Dependence

    phase 2 other active

    1 trial
  26. CRB-601 monoclonal antibody

    Corbus Pharmaceuticals Holdings

    Solid Tumor

    phase 2 small molecule active

    1 trial
  27. CRB-701

    Corbus Pharmaceuticals Holdings

    Solid Tumor, Adult

    phase 2 small molecule active

    1 trial
  28. CRCFC-TEICO.SA.2022

    Verona Pharma Ireland Limited

    cystic fibrosis associated to persistent Staphylococcus aureus (including MRSA) infection

    phase 2 small molecule active

    1 trial
  29. CRD-4730, CRD-4730 matching placebo

    Lacuna Pharma Pty Ltd

    Catecholaminergic Polymorphic Ventricular Tachycardia

    phase 2 small molecule active

    1 trial
  30. CRD-4730-201

    Lacuna Pharma Pty Ltd

    Catecholaminergic Polymorphic Ventricular Tachycardia (CPVT)

    phase 2 small molecule active

    1 trial
  31. CRD-750-201

    Lacuna Pharma Pty Ltd

    Heart failure (HF) with reduced ejection fraction (HFrEF)

    phase 2 small molecule active

    1 trial
  32. CRD-750-202

    Lacuna Pharma Pty Ltd

    chronic heart failure

    phase 2 small molecule active

    1 trial
  33. CRISP ITCC-053

    Disc Medicine

    Neuroblastoma (NBL), Rhabdomyosarcoma (RMS), Inflammatory Myofibroblastic Tumors (IMT), Other ALK/ROS1/MET-positive malignancies, Anaplastic Large Cell Lymphoma (ALCL)

    phase 2 small molecule active

    1 trial
  34. CRN04894-09

    Lacuna Pharma Pty Ltd

    CONGENITAL ADRENAL HYPERPLASIA

    phase 2 other active

    1 trial
  35. CRN09682

    Crinetics Pharmaceuticals Europe GmbH

    SST2-positive Neuroendocrine Neoplasms

    phase 2 small molecule active

    1 trial
  36. CRN09682-191

    Lacuna Pharma Pty Ltd

    Metastatic or locally advanced SST2-positive neuroendocrine neoplasms in adults

    phase 2 other active

    1 trial
  37. CRV431 75mg

    Hepion Pharmaceuticals

    NASH - Nonalcoholic Steatohepatitis

    phase 2 small molecule completed

    1 trial
  38. CS-3150

    Daiichi Sankyo

    Diabetic Nephropathy

    phase 2 small molecule completed

    1 trial
  39. CS008

    Lacuna Pharma Pty Ltd

    Rheumatoid Arthritis

    phase 2 small molecule active

    1 trial
  40. CS1001

    Cstone Pharmaceuticals Ireland Limited

    Advanced Refractory Solid Tumors

    phase 2 small molecule completed

    1 trial
  41. CSCI-SKT-B1001

    Nordic Bioscience A/S

    Atopic dermatitis

    phase 2 small molecule active

    1 trial
  42. CSET 2020/3187

    The George Institute

    Adult patients with metastatic and/or unresectable Non-Small Cell Lung Cancer (NSCLC) who progressed on at least one line and not more than three lines of prior therapy for metastatic/unresectable NSCLC

    phase 2 other active

    1 trial
  43. CSET 2022-3571

    The George Institute

    Patients with hormone-receptor negative and HER2-negative (IHC 0, 1+ or IHC 2+/ISH-) breast cancer with early relapse while on (neo) adjuvant systemic treatment or within 12 months from the end of all treatments with curative intent.

    phase 2 other active

    1 trial
  44. CSET 2025/4053

    The George Institute

    Breast cancer

    phase 2 small molecule active

    1 trial
  45. CSET N° 2017/2523

    The George Institute

    Pancreatic well differentiated neuroendocrine tumors (NET)

    phase 2 other active

    1 trial
  46. CSET N° 2020/3188

    The George Institute

    Patients with hormone-receptor positive (HR+) and human epidermal growth factor receptor 2 negative (HER2-negative) advanced breast cancer (ABC) who have already received standard therapy for HR+/HER2-negative ABC, including only one line of chemotherapy for advanced/metastatic disease.

    phase 2 other active

    1 trial
  47. CSET N°2016/2454

    The George Institute

    Metastatic squamous cell carcinoma of head and neck, lung, esophagus, cervix, vagina, vulva or anus to be treated with SBRT

    phase 2 small molecule active

    1 trial
  48. CSET N°2017/2536

    The George Institute

    Adjuvant therapy after salvage surgery of high risk recurrent head and neck squamous cell carcinoma (HNSCC)

    phase 2 small molecule active

    1 trial

Frequently asked questions

How many Phase II pipeline programs are in the directory?

7,238 published programs match this development stage in our ClinicalTrials.gov index.

What defines this pipeline stage?

Phase and status reflect ClinicalTrials.gov registry fields at last sync. See our clinical trial phases reference for methodology.