Saturday, July 11, 2026
🇺🇸 FDA

Intelligence · Clinical pipeline

Phase II Pipeline Programs

Proof-of-concept and dose-finding clinical programs in Phase II development.

Programs 7,238
Sponsors 1,771
Drugs 4,798

Quick answer

NovaPharmaNews tracks 7,238 phase ii pharmaceutical pipeline programs from ClinicalTrials.gov. Proof-of-concept and dose-finding clinical programs in Phase II development.

Top sponsors

Pipeline programs

Page 26 of 151

  1. BO41932

    Hoffmann-La Roche

    Solid tumors

    phase 2 small molecule active

    1 trial

  2. BO42533

    Hoffmann-La Roche

    Squamous cell carcinoma of the head and neck (SCCHN)

    phase 2 small molecule active

    1 trial

  3. BO43249

    Hoffmann-La Roche

    Resectable Stage I-III Non-Small Cell Lung Cancer (NSCLC)

    phase 2 small molecule active

    1 trial

  4. BO43936

    Hoffmann-La Roche

    Untreated Locally Advanced Unresectable or Metastatic Renal Cell Carcinoma

    phase 2 other active

    1 trial

  5. BO44157

    Hoffmann-La Roche

    Previously Untreated Locally Advanced or Metastatic Urothelial Cancer

    phase 2 small molecule active

    1 trial

  6. BO44178

    Hoffmann-La Roche

    Previously untreated locally advanced or metastatic non-small cell lung cancer (NSCLC)

    phase 2 other active

    1 trial

  7. BO44426

    Hoffmann-La Roche

    Untreated Advanced or Metastatic Non-Small Cell Lung Cancer

    phase 2 small molecule active

    1 trial

  8. BO45853

    Hoffmann-La Roche

    Early-Stage, PIK3CA-Mutated Breast Cancer (BC)

    phase 2 small molecule active

    1 trial

  9. BOOST cells

    The George Institute

    Osteogenesis Imperfecta (OI) type III and severe type IV. Severe type of congenital Brittle bone disease.

    phase 2 small molecule active

    1 trial

  10. BOTOX 100 Allergan Units Powder for Solution for Injection

    Disc Medicine

    postoperative pancreatic fistulas

    phase 2 small molecule active

    1 trial

  11. BOTULINUM TOXIN , -

    The George Institute

    Myogenous temporomandibular disorders (TMDM)

    phase 2 small molecule active

    1 trial

  12. BP39144

    Hoffmann-La Roche

    Paroxysmal nocturnal hemoglobinuria (PNH)

    phase 2 small molecule active

    1 trial

  13. BP41072

    Hoffmann-La Roche

    Relapsed/Refractory B-Cell Non-Hodgkin’s Lymphoma (r/r B-cell NHL)

    phase 2 small molecule active

    1 trial

  14. BP42155

    Hoffmann-La Roche

    Alzheimer's disease

    phase 2 small molecule active

    1 trial

  15. BP42772

    Hoffmann-La Roche

    Advanced or metastatic squamous cell carcinoma of the esophagus

    phase 2 other active

    1 trial

  16. BP44745

    Hoffmann-La Roche

    Alzheimer’s Disease

    phase 2 small molecule active

    1 trial

  17. BP45381

    Hoffmann-La Roche

    BCG-Unresponsive High-Risk Non-Muscle Invasive Bladder Cancer (NMIBC)

    phase 2 small molecule active

    1 trial

  18. BP45703

    Hoffmann-La Roche

    Type 2 Diabetes Mellitus (T2D)

    phase 2 small molecule active

    1 trial

  19. BP46016

    Hoffmann-La Roche

    Progressive Forms of Multiple Sclerosis (PMS)

    phase 2 small molecule active

    1 trial

  20. BPF-CCRT (run-in)

    Hospital Authority, Hong Kong

    Stage III Esophageal Squamous Cell Carcinoma

    phase 2 small molecule active

    1 trial

  21. BPS804

    Mereo BioPharma Group plc

    Hypophosphatasia

    phase 2 small molecule completed

    1 trial

  22. BPS804

    Ultragenyx UK Limited

    Osteogenesis Imperfecta

    phase 2 small molecule completed

    1 trial

  23. BPS804

    Mereo BioPharma Group plc

    Chronic-kidney Disease Stage 5D on Stable Hemodialysis

    phase 2 small molecule terminated

    1 trial

  24. BPS804

    Mereo BioPharma Group plc

    Osteogenesis Imperfecta

    phase 2 small molecule terminated

    1 trial

  25. BPS804 20mg/Kg

    Mereo BioPharma Group plc

    Osteopenia

    phase 2 small molecule completed

    1 trial

  26. BRII-179

    Vir Biotechnology

    For Treatment of Chronic Hepatitis B Virus Infection

    phase 2 mab active

    1 trial

  27. BRII-835 (VIR-2218)

    Vir Biotechnology

    Hepatitis B, Chronic

    phase 2 small molecule completed

    1 trial

  28. BSF 208075

    Gilead Sciences Ireland UC

    Pulmonary Hypertension

    phase 2 small molecule completed

    1 trial

  29. BSMO 1-2018

    Wuhan Createrna Science and Technology Co., Ltd

    Basket tumors

    phase 2 small molecule active

    1 trial

  30. BT1718

    BICYCLE THERAPEUTICS

    Advanced Solid Tumours

    phase 2 small molecule completed

    1 trial

  31. BT8009, Zelenectide Pevedotin

    BICYCLE THERAPEUTICS

    NECTIN4 Amplified Advanced Breast Cancer

    phase 2 small molecule active

    1 trial

  32. BT8009-100

    BICYCLE THERAPEUTICS

    Nectin-4 Expressing Advanced Malignancies.

    phase 2 small molecule active

    1 trial

  33. BUL-5/ESD

    Dr. Falk Pharma GmbH

    Prevention of oesophageal strictures in adult patients after endoscopic submucosal dissection

    phase 2 small molecule active

    1 trial

  34. BV-2020/09

    Lacuna Pharma Pty Ltd

    Recurrent wheezing

    phase 2 small molecule active

    1 trial

  35. BVRS-GamVac-Combi

    BRIGHT MINDS BIOSCIENCES INC.

    MERS (Middle East Respiratory Syndrome)

    phase 2 small molecule active

    1 trial

  36. BW-20805 Injection

    Lacuna Pharma Pty Ltd

    Hereditary Angioedema

    phase 2 small molecule active

    1 trial

  37. BXCL501 (180 micrograms)

    BRIGHT MINDS BIOSCIENCES INC.

    Opioid Use Disorder

    phase 2 small molecule active

    1 trial

  38. BXCL501 Sublingual Film

    BioXcel Therapeutics

    Bipolar I Disorder

    phase 2 small molecule completed

    1 trial

  39. BXCL701

    BioXcel Therapeutics

    Metastatic Pancreatic Ductal Adenocarcinoma

    phase 2 small molecule active

    1 trial

  40. BXCL701 plus Pembrolizumab

    BioXcel Therapeutics

    Prostate Cancer

    phase 2 small molecule completed

    1 trial

  41. BZD discontinuation protocol

    BRIGHT MINDS BIOSCIENCES INC.

    Substance Use Disorders

    phase 2 small molecule completed

    1 trial

  42. Baclofen

    BRIGHT MINDS BIOSCIENCES INC.

    Marijuana Dependence

    phase 2 small molecule completed

    1 trial

  43. Baclofen

    BRIGHT MINDS BIOSCIENCES INC.

    Cocaine-Related Disorders

    phase 2 small molecule completed

    1 trial

  44. Bacteriophage

    Adaptive Biotechnologies Corp

    Prosthetic Joint Infection

    phase 2 small molecule terminated

    1 trial

  45. Bacteriophage Therapy

    Adaptive Biotechnologies Corp

    Urinary Tract Infection Bacterial

    phase 2 mab terminated

    1 trial

  46. Bacteriophage Therapy

    Adaptive Biotechnologies Corp

    Osteomyelitis

    phase 2 mab terminated

    1 trial

  47. Bactrim + compresse for Chronic Lymphocytic Leukemia

    Fondazione Telethon ETS

    Chronic Lymphocytic Leukemia

    phase 2 small molecule active

    1 trial

  48. Balinatunfib, Not the same excipients as test

    Sanofi-aventis Healthcare Pty Ltd

    Crohn's disease, Colitis Ulcerative

    phase 2 small molecule active

    1 trial

Frequently asked questions

How many Phase II pipeline programs are in the directory?

7,238 published programs match this development stage in our ClinicalTrials.gov index.

What defines this pipeline stage?

Phase and status reflect ClinicalTrials.gov registry fields at last sync. See our clinical trial phases reference for methodology.

Drug approvals, clinical trials, M&A, event intelligence, and company updates — weekly.

Customize topics & region
Topics
Region

No spam. Unsubscribe anytime. See our privacy policy.