Friday, July 10, 2026

Intelligence · Clinical pipeline

Phase II Pipeline Programs

Proof-of-concept and dose-finding clinical programs in Phase II development.

Programs 7,238
Sponsors 1,771
Drugs 4,798

Quick answer

NovaPharmaNews tracks 7,238 phase ii pharmaceutical pipeline programs from ClinicalTrials.gov. Proof-of-concept and dose-finding clinical programs in Phase II development.

Top sponsors

Pipeline programs

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  1. Autobiographical Memory Flexibility (MemFlex) training

    COGNITION THERAPEUTICS INC

    Major Depressive Disorder

    phase 2 other completed

    1 trial
  2. Autologous (self) mononuclear cells derived from umbilical cord blood

    Regeneron Ireland Designated Activity Company (DAC)

    Hypoplastic Left Heart Syndrome

    phase 2 mab active

    1 trial
  3. Autologous BCMA-targeting CAR T cells

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Multiple Myeloma in Relapse

    phase 2 mab active

    1 trial
  4. Autologous Bone Marrow Mononuclear Cells

    Lxo Ireland Designated Activity Company

    Peripheral Vascular Diseases

    phase 2 other completed

    1 trial
  5. Autologous CD5 CAR T-cells

    The First People's Hospital of Lianyungang

    T-Cell Acute Lymphocytic Leukemia

    phase 2 small molecule active

    1 trial
  6. Autologous CD5 CAR T-cells

    Universal Integrated

    T-Cell Acute Lymphocytic Leukemia

    phase 2 small molecule active

    1 trial
  7. Autologous CD7 CAR T-cell

    Universal Integrated

    T-cell Acute Lymphoblastic Leukemia

    phase 2 small molecule active

    1 trial
  8. Autologous Fat Transfer

    United Therapeutics Europe Ltd

    Wound

    phase 2 other completed

    1 trial
  9. Autologous Room Temperature stored Platelet transfusion

    United Therapeutics Europe Ltd

    Reversal of Platelet Aggregation Inhibitors

    phase 2 mab active

    1 trial
  10. Autologous Skin Fibroblasts

    United Therapeutics Europe Ltd

    Amputation

    phase 2 mab active

    1 trial
  11. Autologous Tumor Infiltrating Lymphocytes MDA-TIL

    Iovance Biotherapeutics B.V.

    Malignant Solid Neoplasm

    phase 2 mab terminated

    1 trial
  12. Autologous Volar Fibroblast Injection into the Terminal Limb of Amputees

    United Therapeutics Europe Ltd

    Amputation

    phase 2 other active

    1 trial
  13. Autologous adipose derived mesenchymal stem cells

    Lxo Ireland Designated Activity Company

    Critical Limb Ischemia (CLI)

    phase 2 small molecule completed

    1 trial
  14. Autologous bone marrow mononuclear cell transplantation

    EuroGen Pharmaceuticals Ltd

    Spinal Cord Injury

    phase 2 mab terminated

    1 trial
  15. Autologous hematopoietic stem cell infusion

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Prolonged Cytopenia Following CAR-T Therapy

    phase 2 mab active

    1 trial
  16. Autologous mesenchymal stem cells from adipose tissue.

    Lxo Ireland Designated Activity Company

    Autoimmune Diseases

    phase 2 other completed

    1 trial
  17. Avastin /ml concentrate for Advanced non-small-cell lung ca…

    Fondazione Telethon ETS

    Advanced non-small-cell lung cancer

    phase 2 small molecule active

    1 trial
  18. Avastin /ml concentrate for Patients with ras-mutated metas…

    Fondazione Telethon ETS

    Patients with ras-mutated metastatIc colorectal cancer

    phase 2 small molecule active

    1 trial
  19. Avastin 25 mg/ml concentrate for solution for infusion.

    Disc Medicine

    Barrett's esophagus, Colon carcinoma, gastrointestinal dysplasia

    phase 2 small molecule active

    1 trial
  20. Avastin® (bevacizumab)

    United Therapeutics Europe Ltd

    Corneal Neovascularization

    phase 2 small molecule completed

    1 trial
  21. Avatrombopag

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Severe Aplastic Anemia

    phase 2 small molecule active

    2 trials
  22. Avatrombopag

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Immune Thrombocytopenia

    phase 2 small molecule active

    1 trial
  23. Avatrombopag

    Hospital Authority, Hong Kong

    Chemotherapy-induced Thrombocytopenia

    phase 2 small molecule active

    1 trial
  24. Avelumab

    Nektar Therapeutics UK Limited

    Locally Advanced or Metastatic Urothelial Carcinoma

    phase 2 small molecule active

    1 trial
  25. Avelumab and Pepinemab

    VACCINEX, INC.

    Metastatic Pancreatic Adenocarcinoma

    phase 2 small molecule active

    1 trial
  26. Avenciguat

    Boehringer Ingelheim

    Chronic Kidney Disease

    phase 2 small molecule completed

    1 trial
  27. Avutometinib

    United Therapeutics Europe Ltd

    Glioblastoma Multiforme (GBM)

    phase 2 small molecule active

    1 trial
  28. Axatilimab

    Syndax Pharmaceuticals

    Chronic Graft-versus-host-disease

    phase 2 small molecule active

    2 trials
  29. Axatilimab

    Syndax Pharmaceuticals

    Idiopathic Pulmonary Fibrosis

    phase 2 small molecule active

    1 trial
  30. Axatilimab (INCA034176)

    Incyte

    Chronic Graft-Versus-Host Disease

    phase 2 small molecule active

    1 trial
  31. Axitinib

    United Therapeutics Europe Ltd

    Clear-cell Metastatic Renal Cell Carcinoma

    phase 2 small molecule completed

    1 trial
  32. Axitinib

    ADIAL PHARMACEUTICALS, INC.

    Melanoma

    phase 2 small molecule completed

    1 trial
  33. Axumin PET/CT

    HALOZYME THERAPEUTICS, INC.

    Prostate Cancer

    phase 2 small molecule completed

    1 trial
  34. Azacitidine

    Janssen Cilag International NV

    Myelodysplastic Syndromes

    phase 2 small molecule terminated

    1 trial
  35. Azacitidine

    The First People's Hospital of Lianyungang

    Philadelphia Chromosome

    phase 2 small molecule completed

    1 trial
  36. Azacitidine

    Takeda

    Myelodysplastic Syndromes

    phase 2 small molecule completed

    2 trials
  37. Azacitidine

    Syndax Pharmaceuticals

    Non-Small Cell Lung Cancer

    phase 2 small molecule completed

    1 trial
  38. Azacitidine (AZA) with Ruxolitinib

    The First People's Hospital of Lianyungang

    MDS/MPN

    phase 2 small molecule active

    1 trial
  39. Azacitidine Injection

    The First People's Hospital of Lianyungang

    B Acute Lymphoblastic Leukemia

    phase 2 small molecule active

    1 trial
  40. Azacitidine in Combination With Venetoclax

    The First People's Hospital of Lianyungang

    Hematologic Malignancy

    phase 2 small molecule active

    1 trial
  41. Azeliragon

    vTv Therapeutics

    Alzheimer Disease

    phase 2 small molecule terminated

    1 trial
  42. Azenosertib

    Zentalis Pharmaceuticals

    Breast Cancer

    phase 2 small molecule terminated

    1 trial
  43. Azenosertib

    Zentalis Pharmaceuticals

    Uterine Serous Carcinoma

    phase 2 small molecule active

    2 trials
  44. Azenosertib

    Zentalis Pharmaceuticals

    Ovarian Cancer

    phase 2 small molecule completed

    1 trial
  45. Azilsartan

    Takeda

    Hypertension

    phase 2 small molecule completed

    2 trials
  46. B-CIT and SPECT imaging

    United Therapeutics Europe Ltd

    Parkinson Disease

    phase 2 small molecule completed

    1 trial
  47. B-MAD chemotherapy

    Takeda

    Extranodal NK/T-cell Lymphoma

    phase 2 small molecule completed

    1 trial
  48. B013

    BRIGHT MINDS BIOSCIENCES INC.

    Platinum-resistant Recurrent Ovarian Cancer

    phase 2 small molecule active

    1 trial

Frequently asked questions

How many Phase II pipeline programs are in the directory?

7,238 published programs match this development stage in our ClinicalTrials.gov index.

What defines this pipeline stage?

Phase and status reflect ClinicalTrials.gov registry fields at last sync. See our clinical trial phases reference for methodology.