Friday, July 10, 2026

Intelligence · Clinical pipeline

Phase II Pipeline Programs

Proof-of-concept and dose-finding clinical programs in Phase II development.

Programs 7,238
Sponsors 1,771
Drugs 4,798

Quick answer

NovaPharmaNews tracks 7,238 phase ii pharmaceutical pipeline programs from ClinicalTrials.gov. Proof-of-concept and dose-finding clinical programs in Phase II development.

Top sponsors

Pipeline programs

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  1. Antimicrobial agent

    Lakewood-Amedex Biotherapeutics

    Diabetic Foot Ulcers (DFUs)

    phase 2 small molecule active

    1 trial
  2. Antipyrine-benzocaine otic solution

    United Therapeutics Europe Ltd

    Asthma

    phase 2 small molecule active

    1 trial
  3. Antithymocyte globulin (ATG)

    Ultragenyx UK Limited

    Myelodysplastic Syndrome

    phase 2 small molecule active

    1 trial
  4. Anvumetostat

    Amgen

    Advanced MTAP-null Solid Tumors

    phase 2 small molecule active

    1 trial
  5. Apalutamide

    Janssen Cilag International NV

    Salivary Gland Neoplasms

    phase 2 small molecule active

    1 trial
  6. Apatinib

    The First People's Hospital of Lianyungang

    Advanced Solid Tumors

    phase 2 small molecule active

    1 trial
  7. Apatinib

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Breast Cancer Metastatic

    phase 2 small molecule active

    1 trial
  8. Apatinib

    The First People's Hospital of Lianyungang

    Lung Cancer

    phase 2 small molecule active

    1 trial
  9. Apatinib

    Chinese University of Hong Kong

    Head and Neck Neoplasms

    phase 2 small molecule active

    1 trial
  10. Apatinib

    The First People's Hospital of Lianyungang

    Non Small Cell Lung Cancer

    phase 2 small molecule active

    1 trial
  11. Apatinib

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Lung Cancer

    phase 2 small molecule active

    1 trial
  12. Apatinib

    The First People's Hospital of Lianyungang

    Systematic Review of the pCR Rate of Apatinib Combined With Albumin Paclitaxel and Carboplatin Regimen for Neoadjuvant Therapy of Triple-negative Breast Cancer

    phase 2 small molecule active

    1 trial
  13. Apatinib

    The First People's Hospital of Lianyungang

    Intrahepatic Cholangiocarcinoma

    phase 2 small molecule active

    1 trial
  14. Apatinib

    The First People's Hospital of Lianyungang

    Advanced Esophageal Squamous Carcinoma

    phase 2 small molecule active

    1 trial
  15. Apatinib

    The First People's Hospital of Lianyungang

    Malignant Ascites

    phase 2 small molecule active

    1 trial
  16. Apatinib

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Metastatic Gastric Adenocarcinoma

    phase 2 small molecule active

    1 trial
  17. Apatinib

    Hospital Authority, Hong Kong

    Soft Tissue Sarcoma, Adult, Stage II

    phase 2 small molecule active

    1 trial
  18. Apatinib

    The First People's Hospital of Lianyungang

    Thyroid

    phase 2 small molecule active

    1 trial
  19. Apatinib

    The First People's Hospital of Lianyungang

    Breast Cancer

    phase 2 small molecule completed

    1 trial
  20. Apatinib Combined With SHR-1210 Injection

    The First People's Hospital of Lianyungang

    Hepatocellular Carcinoma

    phase 2 small molecule active

    1 trial
  21. Apatinib Mesylate +SHR-1210

    Chinese University of Hong Kong

    Hepatocellular Carcinoma

    phase 2 other active

    1 trial
  22. Apatinib mesylate tablet

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Nasopharyngeal Carcinoma

    phase 2 small molecule active

    1 trial
  23. Apatinib mesylate tablets

    The First People's Hospital of Lianyungang

    Gastric Cancer

    phase 2 small molecule active

    1 trial
  24. Apatinib+ SHR-1210(Camrelizumab)

    The First People's Hospital of Lianyungang

    Esophageal Cancer

    phase 2 small molecule active

    1 trial
  25. Apheresis and Bridging Therapy

    The First People's Hospital of Lianyungang

    Large B-cell Lymphoma

    phase 2 other completed

    1 trial
  26. Aplindore

    LIGAND PHARMACEUTICALS INC

    Restless Legs Syndrome

    phase 2 small molecule completed

    1 trial
  27. Aplindore

    LIGAND PHARMACEUTICALS INC

    Early Stage Parkinson's Disease

    phase 2 small molecule completed

    1 trial
  28. Apremilast

    Amgen

    Palmoplantaris Pustulosis

    phase 2 small molecule completed

    1 trial
  29. Aprepitant

    BRIGHT MINDS BIOSCIENCES INC.

    Cannabis Dependence

    phase 2 small molecule completed

    2 trials
  30. Aprepitant

    GlaxoSmithKline

    Nausea and Vomiting

    phase 2 small molecule completed

    1 trial
  31. Aprepitant injectable emulsion

    Heron Therapeutics

    COVID-19

    phase 2 small molecule terminated

    1 trial
  32. Ara-C Group

    The First People's Hospital of Lianyungang

    Acute Myeloid Leukemia

    phase 2 small molecule active

    1 trial
  33. Aramchol

    Galmed Pharmaceuticals

    Gallstones

    phase 2 small molecule terminated

    1 trial
  34. Aramchol

    Galmed Pharmaceuticals

    Non-Alcoholic Fatty Liver Disease

    phase 2 small molecule completed

    1 trial
  35. Aramchol

    Galmed Pharmaceuticals

    Fatty Liver

    phase 2 small molecule completed

    1 trial
  36. Aramchol meglumine

    Galmed Pharmaceuticals

    Primary Sclerosing Cholangitis

    phase 2 small molecule terminated

    1 trial
  37. Arazasetron besylate

    Orion Laboratories Pty.

    Cisplatine induced hearing loss

    phase 2 small molecule active

    1 trial
  38. Arbaclofen Placarbil

    Indivior Pty Ltd

    Alcohol Use Disorder

    phase 2 small molecule completed

    1 trial
  39. Argon/Oxygen mixture, OXYGEN

    Istituto Gentili S.r.l.

    Cardiac arrest

    phase 2 small molecule active

    1 trial
  40. Aripiprazole

    BRIGHT MINDS BIOSCIENCES INC.

    Substance Abuse

    phase 2 small molecule completed

    1 trial
  41. Aripiprazole + Cocaine

    BRIGHT MINDS BIOSCIENCES INC.

    Cocaine Abuse

    phase 2 small molecule completed

    1 trial
  42. Aritinercept

    Aurinia Pharmaceuticals

    Myasthenia Gravis, Generalized

    phase 2 small molecule active

    1 trial
  43. Arm 1: Standard Synchronous Group

    The First People's Hospital of Lianyungang

    Advanced Non-Small Cell Lung Cancer (NSCLC)

    phase 2 small molecule active

    1 trial
  44. Arm A

    The First People's Hospital of Lianyungang

    Esophageal Cancer

    phase 2 small molecule active

    1 trial
  45. Arm T1: Primatene Mist HFA

    Amphastar France Pharmaceuticals

    Asthma

    phase 2 small molecule completed

    1 trial
  46. Arm1

    Hospital Authority, Hong Kong

    Oral Squamous Cell Carcinoma

    phase 2 small molecule active

    1 trial
  47. Armodafinil

    Teva Pharma GmbH

    Stroke

    phase 2 small molecule completed

    1 trial
  48. Armodafinil

    Teva Pharma GmbH

    Bipolar I Depression

    phase 2 small molecule completed

    1 trial

Frequently asked questions

How many Phase II pipeline programs are in the directory?

7,238 published programs match this development stage in our ClinicalTrials.gov index.

What defines this pipeline stage?

Phase and status reflect ClinicalTrials.gov registry fields at last sync. See our clinical trial phases reference for methodology.