Friday, July 10, 2026
🇺🇸 FDA

Intelligence · Clinical pipeline

Phase II Pipeline Programs

Proof-of-concept and dose-finding clinical programs in Phase II development.

Programs 7,238
Sponsors 1,771
Drugs 4,798

Quick answer

NovaPharmaNews tracks 7,238 phase ii pharmaceutical pipeline programs from ClinicalTrials.gov. Proof-of-concept and dose-finding clinical programs in Phase II development.

Top sponsors

Pipeline programs

Page 2 of 151

  1. 1378-0023

    Boehringer Ingelheim

    chronic kidney disease

    phase 2 small molecule active

    1 trial

  2. 13914704178

    The First People's Hospital of Lianyungang

    Locally Advanced Esophageal Squamous Cell Carcinoma

    phase 2 small molecule active

    1 trial

  3. 1403-0032

    Boehringer Ingelheim

    Solid tumours

    phase 2 small molecule active

    1 trial

  4. 1425-0003

    Boehringer Ingelheim

    Crohn`s Disease (CD)

    phase 2 small molecule active

    1 trial

  5. 14308

    Bayer AG

    Patients symptomatic with pulmonary hypertension associated with left ventricular systolic dysfunction (PH-sLVD)

    phase 2 small molecule active

    1 trial

  6. 1434-0004

    Boehringer Ingelheim

    Focal segmental glomerulosclerosis

    phase 2 small molecule active

    1 trial

  7. 1447-0005

    Boehringer Ingelheim

    Major depressive disorder

    phase 2 other active

    1 trial

  8. 1462-0004

    Boehringer Ingelheim

    idiopathic pulmonary fibrosis

    phase 2 small molecule active

    1 trial

  9. 1462rot25ct

    Lacuna Pharma Pty Ltd

    Parkinson's disease

    phase 2 small molecule active

    1 trial

  10. 1479-0012

    Boehringer Ingelheim

    gastroesophageal junction adenocarcinoma, metastatic gastric adenocarcinoma, metastatic breast cancer, metastatic colorectal cancer, esophageal adenocarcinoma

    phase 2 small molecule active

    1 trial

  11. 1479-0044

    Boehringer Ingelheim

    locally advanced or metastatic NSCLC

    phase 2 small molecule active

    1 trial

  12. 1485-0018

    Boehringer Ingelheim

    Centre-involved diabetic macular edema

    phase 2 small molecule active

    1 trial

  13. 1490-0004

    Boehringer Ingelheim

    Progressive pulmonary fibrosis (PPF), Idiopathic pulmonary fibrosis (IPF)

    phase 2 small molecule active

    1 trial

  14. 1504-0001

    Boehringer Ingelheim

    Cystic fibrosis

    phase 2 small molecule active

    1 trial

  15. 1509-0004

    Boehringer Ingelheim

    Systemic lupus erythematosus

    phase 2 small molecule active

    1 trial

  16. 1537-LYMG

    Ningbo Cancer Hospital

    Advanced stage Hodgkin Lymphoma

    phase 2 small molecule active

    1 trial

  17. 1570-CL-0101

    Astellas Pharma GmbH

    Advanced Solid Tumors

    phase 2 small molecule active

    1 trial

  18. 16-739

    Disc Medicine

    Perinatal Arterial Ischemic Stroke (PAIS)

    phase 2 small molecule active

    1 trial

  19. 160001

    Takeda

    Primary Immunodeficiency Diseases (PID)

    phase 2 small molecule completed

    1 trial

  20. 160002

    Takeda

    Immune Thrombocytopenic Purpura (ITP)

    phase 2 small molecule completed

    1 trial

  21. 1634

    Ningbo Cancer Hospital

    Newly Diagnosed Medulloblastoma

    phase 2 small molecule active

    1 trial

  22. 16mg，KB

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Sepsis

    phase 2 small molecule active

    1 trial

  23. 17000139BLC2001

    Janssen-Cilag International N.V.

    Non-Muscle-Invasive Urothelial Carcinoma (NMIBC) of the Bladder

    phase 2 small molecule active

    1 trial

  24. 17000139BLC2002

    Janssen-Cilag International N.V.

    Muscle-Invasive Urothelial Carcinoma of the Bladder

    phase 2 small molecule active

    1 trial

  25. 17456

    Disc Medicine

    Chronic Kidney Disease

    phase 2 small molecule active

    1 trial

  26. 177Lu PSMA I&T solution for injection

    Wuhan Createrna Science and Technology Co., Ltd

    Recurrent grade 3 and grade 4 glioma

    phase 2 small molecule active

    1 trial

  27. 177Lu girentuximab

    Telix Innovations

    Advanced Cancer

    phase 2 small molecule active

    1 trial

  28. 177Lu-DOTA-EB-FAPI radionuclide therapy

    The First People's Hospital of Lianyungang

    Refractory Solid Tumor

    phase 2 small molecule completed

    1 trial

  29. 177Lu-DOTA-TLX591

    Telix Innovations

    Prostate Cancer

    phase 2 mab completed

    1 trial

  30. 177Lu-J591

    United Therapeutics Europe Ltd

    Prostate Cancer

    phase 2 small molecule active

    1 trial

  31. 177Lu-PSMA I&T_IRSTIRCCS

    Istituto Gentili S.r.l.

    Oligometastatic prostate carcinoma

    phase 2 small molecule active

    1 trial

  32. 177Lu-PSMA I&T_IRSTIRCCS

    Istituto Gentili S.r.l.

    PSMA PET/CT positive advanced/metastatic tumours

    phase 2 small molecule active

    1 trial

  33. 177Lu-PSMA-617

    United Therapeutics Europe Ltd

    Metastatic Hormone Naive Prostate Cancer

    phase 2 small molecule active

    1 trial

  34. 18-0254

    BRIGHT MINDS BIOSCIENCES INC.

    Methamphetamine Use Disorder

    phase 2 other active

    1 trial

  35. 1801

    ACTUATE THERAPEUTICS, INC.

    Refractory Hematologic Malignancies or Solid Tumors

    phase 2 small molecule active

    1 trial

  36. 18870

    Disc Medicine

    Chronic obstructive pulmonary disease (COPD), amyotrophic lateral sclerosis (ALS), multiple sclerosis (MS), and atypical Parkinson disorder (APD), particularly multiple system atrophy (MSA), progressive supranuclear palsy (PSP), and corticobasal syndrome (CBS).

    phase 2 small molecule active

    1 trial

  37. 18F-92

    The First People's Hospital of Lianyungang

    Alzheimer's Disease

    phase 2 small molecule active

    1 trial

  38. 18FMC225_FPG

    Fondazione Telethon ETS

    depression

    phase 2 small molecule active

    1 trial

  39. 19310

    Disc Medicine

    Head and neck squamous cell carcinoma (HNSCC)

    phase 2 other active

    1 trial

  40. 1μg/ml ESAT6-CFP10 and tuberculin purified protein derivative

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Tuberculosis

    phase 2 mab completed

    1 trial

  41. 2-deoxyglucose

    United Therapeutics Europe Ltd

    Prostate Cancer

    phase 2 small molecule terminated

    1 trial

  42. 2-methoxyestradiol

    CASI Pharmaceuticals

    Relapsed Multiple Myeloma

    phase 2 small molecule completed

    1 trial

  43. 20% N2O

    BRIGHT MINDS BIOSCIENCES INC.

    Opioid-Related Disorders

    phase 2 small molecule completed

    1 trial

  44. 20-27 PaTcH

    Ningbo Cancer Hospital

    Metastatic refractory Pancreatic Cancer

    phase 2 small molecule active

    1 trial

  45. 200908

    GlaxoSmithKline

    Systemic Lupus Erythematosus

    phase 2 small molecule active

    1 trial

  46. 201

    Y-Mabs Therapeutics A/S

    Treatment of high-risk neuroblastoma patients with primary refractory disease or incomplete response to salvage treatment in bone and/or bone marrow

    phase 2 small molecule active

    1 trial

  47. 2016/2369

    The George Institute

    pediatric cancer

    phase 2 small molecule active

    1 trial

  48. 2017/2558

    The George Institute

    Resectable mucosal melanomas

    phase 2 small molecule active

    1 trial

Frequently asked questions

How many Phase II pipeline programs are in the directory?

7,238 published programs match this development stage in our ClinicalTrials.gov index.

What defines this pipeline stage?

Phase and status reflect ClinicalTrials.gov registry fields at last sync. See our clinical trial phases reference for methodology.

Drug approvals, clinical trials, M&A, event intelligence, and company updates — weekly.

Customize topics & region
Topics
Region

No spam. Unsubscribe anytime. See our privacy policy.