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Intelligence · Clinical Pipeline

Phase II Pipeline Programs

Proof-of-concept and dose-finding clinical programs in Phase II development.

Programs
7,238

Quick answer

NovaPharmaNews tracks 7,238 phase ii pharmaceutical pipeline programs from ClinicalTrials.gov. Proof-of-concept and dose-finding clinical programs in Phase II development.

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  1. recombinant human Angiostatin protein

    CASI Pharmaceuticals

    Carcinoma, Non-Small-Cell Lung

    phase 2 small molecule completed

    1 trial

  2. recombinant human endostatin

    Peking University Third Hospital

    Melanoma

    phase 2 small molecule active

    1 trial

  3. recombinant human erythropoietin

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Hypoxic-Ischemic Encephalopathy

    phase 2 small molecule completed

    1 trial

  4. recombinant human erythropoietin (rhEpo)

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Infant, Premature

    phase 2 small molecule active

    1 trial

  5. recombinant human growth hormone

    Affiliated Hospital of Jiangnan University

    Phelan-McDermid Syndrome

    phase 2 small molecule completed

    1 trial

  6. recombinant humanized anti-CD25 monoclonal antibody

    The First People's Hospital of Lianyungang

    Transfusion Dependent Thalassemia

    phase 2 small molecule active

    1 trial

  7. relaxin

    Ultragenyx UK Limited

    Systemic Sclerosis

    phase 2 small molecule completed

    1 trial

  8. remicade (anti tumor necrosis factor inhibitor)

    Hospital Authority, Hong Kong

    Takayasu's Arteritis

    phase 2 small molecule active

    1 trial

  9. rencofilstat, 75 mg

    Hepion Pharmaceuticals

    NASH With Fibrosis

    phase 2 small molecule completed

    1 trial

  10. retinal pigment epithelium transplantation

    The First People's Hospital of Lianyungang

    Dry Age-related Macular Degeneration

    phase 2 mab active

    1 trial

  11. rezatapopt

    PMV Pharmaceuticals

    Advanced Solid Tumor

    phase 2 small molecule active

    1 trial

  12. rhASA

    Shire

    Late Metachromatic Leukodystrophy (MLD)

    phase 2 small molecule active

    1 trial

  13. rhASA

    Shire

    Late Metachromatic Leukodystrophy (MLD)

    phase 2 small molecule active

    1 trial

  14. rhGM-CSF

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Pulmonary Alveolar Proteinosis

    phase 2 small molecule active

    1 trial

  15. rhHNS-10 mg

    Takeda

    Sanfilippo Syndrome

    phase 2 mab terminated

    1 trial

  16. rhIGF-1/rhIGFBP-3

    Takeda

    Retinopathy of Prematurity (ROP)

    phase 2 small molecule completed

    1 trial

  17. rhIGF-I/rhIGFBP-3

    Takeda

    Retinopathy of Prematurity (ROP)

    phase 2 small molecule completed

    1 trial

  18. rhNGF New Lyo Formulation, OXYBUPROCAINE , SODIUM CHLORIDE , rhNGF New Lyo Formulation, The placebo consists of a lyophilized product packaged in 2R siliconized glass class I vials closed with a stopper and a flip off cap and administered after reconstitution with 2mL of diluent contained into a 2R glass class I vials closed with a stopper and a flip off cap. The diluent consists of DMSO, Sesame Extract 98%, Kollifor HS 0.15%, Sodium Chloride, Water For Injection. The product is reconstituted using an ada

    Dompe' Farmaceutici S.p.A.

    Dry Eye

    phase 2 small molecule active

    1 trial

  19. ribavirin (RBV)

    Boehringer Ingelheim

    Hepatitis C

    phase 2 small molecule completed

    1 trial

  20. ribose

    Ultragenyx UK Limited

    5'-Nucleotidase Syndrome

    phase 2 small molecule completed

    1 trial

  21. riliprubart

    Sanofi-aventis Healthcare Pty Ltd

    Chronic inflammatory demyelinating polyradiculoneuropathy

    phase 2 small molecule active

    1 trial

  22. riliprubart, riliprubart

    Sanofi-aventis Healthcare Pty Ltd

    Transplant Rejection

    phase 2 small molecule active

    1 trial

  23. risperidone

    Ultragenyx UK Limited

    Tourette Syndrome

    phase 2 small molecule completed

    1 trial

  24. rituximab

    Chinese University of Hong Kong

    Systemic Lupus Erythematosus

    phase 2 small molecule completed

    1 trial

  25. rituximab

    Ultragenyx UK Limited

    Purpura, Thrombocytopenic, Idiopathic

    phase 2 small molecule completed

    1 trial

  26. rituximab

    Children's Hospital of Fudan University

    Lymphoproliferative Disorder

    phase 2 mab completed

    1 trial

  27. rituximab

    United Therapeutics Europe Ltd

    Lymphoma

    phase 2 mab completed

    1 trial

  28. rituximab /Dexamethasone/cyclophosphamide

    The First People's Hospital of Lianyungang

    Treatment

    phase 2 small molecule active

    1 trial

  29. rolistobart, KEYTRUDA 25 mg/mL concentrate for solution for infusion, PACLITAXEL , CARBOPLATIN , MK-4830, MK-4830, PEMETREXED , boserolimab, vibostolimab

    Merck Sharp and Dohme

    non-small cell lung cancer

    phase 2 small molecule active

    1 trial

  30. rolistobart, MK-4830, KEYTRUDA 25 mg/mL concentrate for solution for infusion, MK-4830

    Merck Sharp and Dohme

    Non-small Cell Lung Cancer (NSCLC)

    phase 2 small molecule active

    1 trial

  31. rolistobart, boserolimab, MK-4830, KEYTRUDA 25 mg/mL concentrate for solution for infusion, MK-4830

    Merck Sharp and Dohme

    Non-small Cell Lung Cancer

    phase 2 small molecule active

    1 trial

  32. sabirnetug

    Acumen Pharmaceuticals

    Alzheimer Disease

    phase 2 small molecule active

    1 trial

  33. sapablursen

    IONIS PHARMACEUTICALS INC

    Phlebotomy Dependent Polycythemia Vera

    phase 2 small molecule active

    1 trial

  34. sapablursen

    IONIS PHARMACEUTICALS INC

    Beta Thalassemia Intermedia

    phase 2 small molecule terminated

    1 trial

  35. sapropterin

    BioMarin Pharmaceutical Australia Pty Ltd

    Autistic Disorder

    phase 2 small molecule completed

    1 trial

  36. sarcosine

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Schizophrenia

    phase 2 small molecule completed

    1 trial

  37. sarilumab

    Sanofi-aventis Healthcare Pty Ltd

    Systemic Juvenile Idiopathic Arthritis (sJIA)

    phase 2 small molecule active

    1 trial

  38. saxagliptin

    KYOWA KIRIN AUSTRALIA PTY LTD

    Diabetes, Type 2

    phase 2 small molecule completed

    1 trial

  39. scAAV8OTC

    Ultragenyx UK Limited

    Ornithine Transcarbamylase (OTC) Deficiency

    phase 2 gene therapy completed

    1 trial

  40. scAAV9/AGA

    Ultragenyx UK Limited

    Aspartylglucosaminuria

    phase 2 gene therapy active

    1 trial

  41. self-expandable 125I radioactive seeds-loaded-stent

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Cholangiocellular Carcinoma

    phase 2 other completed

    1 trial

  42. selinexor

    Karyopharm Therapeutics Inc

    Richter's Transformation

    phase 2 small molecule terminated

    1 trial

  43. selinexor (KPT-330)

    Karyopharm Therapeutics Inc

    Myelodysplastic Syndromes

    phase 2 small molecule completed

    1 trial

  44. serlopitant

    VYNE Therapeutics

    Prurigo Nodularis

    phase 2 small molecule completed

    1 trial

  45. setrusumab

    Mereo BioPharma Group plc

    Osteogenesis Imperfecta, Type I

    phase 2 small molecule completed

    1 trial

  46. sham group will undergo a procedure that will closely mimic the active injection but with no penetration of the globe.

    Laboratoire HRA Pharma

    Retinitis Pigmentosa

    phase 2 small molecule active

    1 trial

  47. sham group will undergo a procedure that will closely mimic the active injection but with no penetration of the globe.

    Laboratoire HRA Pharma

    Retinitis Pigmentosa

    phase 2 small molecule active

    1 trial

  48. silevertinib (BDTX-1535) monotherapy

    Blackmores Limited

    Non-Small Cell Lung Cancer

    phase 2 small molecule active

    1 trial

Frequently asked questions

How many Phase II pipeline programs are in the directory?

7,238 published programs match this development stage in our ClinicalTrials.gov index.

What defines this pipeline stage?

Phase and status reflect ClinicalTrials.gov registry fields at last sync. See our clinical trial phases reference for methodology.

Data attribution: Data sources · All pipeline programs

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