🇺🇸 FDA

Intelligence · Clinical Pipeline

Phase II Pipeline Programs

Proof-of-concept and dose-finding clinical programs in Phase II development.

Programs
7,238

Quick answer

NovaPharmaNews tracks 7,238 phase ii pharmaceutical pipeline programs from ClinicalTrials.gov. Proof-of-concept and dose-finding clinical programs in Phase II development.

Top sponsors

Page 146 of 151

  1. iv ibuprofen

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Extremely Premature Infants

    phase 2 small molecule active

    1 trial

  2. ivonescimab

    CERO THERAPEUTICS HOLDINGS, INC.

    pleural mesothelioma

    phase 2 small molecule active

    1 trial

  3. ivosidenib and nivolumab

    Agios Netherlands B.V.

    Advanced Solid Tumor

    phase 2 small molecule completed

    1 trial

  4. killed oral cholera vaccine

    International Peace Maternity and Child Health Hospital

    Cholera

    phase 2 mab completed

    1 trial

  5. l-tetrahydropalmatine (l-THP)

    BRIGHT MINDS BIOSCIENCES INC.

    Cocaine Use

    phase 2 small molecule terminated

    1 trial

  6. lactulose

    Ultragenyx UK Limited

    Portal Hypertension

    phase 2 small molecule completed

    1 trial

  7. lanadelumab

    Takeda

    COVID-19

    phase 2 mab completed

    1 trial

  8. laquinimod 0.3

    Teva Pharma GmbH

    Relapsing Remitting Multiple Sclerosis

    phase 2 small molecule completed

    1 trial

  9. lenalidomide combined with rituximab

    The First People's Hospital of Lianyungang

    Diffuse Large B Cell Lymphoma

    phase 2 small molecule active

    1 trial

  10. lestaurtinib

    Teva Pharma GmbH

    Polycythemia Vera

    phase 2 small molecule completed

    1 trial

  11. leucovorin+5-FU

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Colonic Diseases

    phase 2 small molecule active

    1 trial

  12. leucovorin, oxaliplatin, docetaxel, S-1

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Gastric Cancer

    phase 2 small molecule active

    1 trial

  13. leuprolide

    Ultragenyx UK Limited

    Spinal Muscular Atrophy

    phase 2 small molecule completed

    1 trial

  14. leuprolide

    Ultragenyx UK Limited

    Hyperandrogenism

    phase 2 small molecule completed

    1 trial

  15. leuprolide acetate

    Ultragenyx UK Limited

    Acanthosis Nigricans

    phase 2 small molecule completed

    1 trial

  16. levamisole

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Anemia

    phase 2 small molecule active

    1 trial

  17. levetiracetam

    BRIGHT MINDS BIOSCIENCES INC.

    Cocaine Dependence

    phase 2 small molecule completed

    2 trials

  18. levodopa

    United Therapeutics Europe Ltd

    Parkinson Disease

    phase 2 small molecule completed

    1 trial

  19. levodopa

    BRIGHT MINDS BIOSCIENCES INC.

    Cocaine Dependence

    phase 2 small molecule completed

    1 trial

  20. levothyroxine sodium

    Xeris Biopharma Holdings

    Hypothyroidism

    phase 2 small molecule completed

    1 trial

  21. linaclotide acetate

    IRONWOOD PHARMACEUTICALS INC

    Chronic Constipation

    phase 2 small molecule completed

    1 trial

  22. linagliptin low dose

    Boehringer Ingelheim

    Diabetes Mellitus, Type 2

    phase 2 small molecule completed

    1 trial

  23. linrodostat mesylate; IDO1 inhibitor, linrodostat mesylate; IDO1 inhibitor, Ipilimumab, Relatlimab intravenous, OPDIVO 10 mg/mL concentrate for solution for infusion., linrodostat mesylate; IDO1 inhibitor, Ipilimumab

    Bristol-Myers Squibb Australia Pty Ltd

    Advanced Malignant Tumors

    phase 2 small molecule active

    1 trial

  24. lisdexamfetamine dimesylate (SPD489)

    Takeda

    Binge Eating Disorder

    phase 2 small molecule completed

    1 trial

  25. long course radiotherapy + capecitabine + PD-1 monoclonal antibody treatment combinations

    BEONE MEDICINES AUS PTY LTD

    Colorectal Neoplasms

    phase 2 other active

    1 trial

  26. lorcaserin

    BRIGHT MINDS BIOSCIENCES INC.

    Nicotine Dependence

    phase 2 small molecule completed

    1 trial

  27. lotilaner

    Tarsus Pharmaceuticals

    Ocular Rosacea

    phase 2 small molecule active

    1 trial

  28. low dose Bivalent Enterovirus Vaccine (Vero Cell), Inactivated

    Sinovac Research and Development Co.,

    Hand, Foot and Mouth Disease

    phase 2 mab active

    1 trial

  29. low-dose Recombinant SARS-CoV-2 Vaccine (CHO cell)

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    COVID-19

    phase 2 mab completed

    1 trial

  30. low-dose lymphocyte immunotherapy

    Nanjing Zenshine Pharmaceuticals

    Unexplained Recurrent Miscarriage and Recurrent Implantation Failure

    phase 2 other completed

    1 trial

  31. lurbinectedin, JEMPERLI 500 mg concentrate for solution for infusion

    The George Institute

    Advanced/Recurrent Endometrial Cancer Patients with Disease Progression after Prior Therapy with Platinum-based Chemotherapy

    phase 2 small molecule active

    1 trial

  32. lymphocyte gene therapy

    Ultragenyx UK Limited

    Mucopolysaccharidosis II

    phase 2 gene therapy completed

    1 trial

  33. lymphokine-activated killer cells

    LISATA THERAPEUTICS, INC.

    Brain and Central Nervous System Tumors

    phase 2 mab terminated

    1 trial

  34. mFOLFOX6 + BIBF 1120

    Galmed Pharmaceuticals

    Colorectal Cancer

    phase 2 small molecule completed

    1 trial

  35. mFOLFOXIRI

    The First People's Hospital of Lianyungang

    Locally Advanced Rectal Cancer

    phase 2 small molecule active

    1 trial

  36. mRNA-3927

    Moderna Biotech Spain

    Propionic Acidemia

    phase 2 small molecule active

    1 trial

  37. mRNA-4157, BCG VACCINE

    Merck Sharp and Dohme

    Bladder cancer

    phase 2 small molecule active

    1 trial

  38. masitinib, masitinib, Placebo to 100mg masitinib, Placebo to 200mg masitinib

    AB Science

    Mast cell activation syndrome

    phase 2 small molecule active

    1 trial

  39. mavrilimumab

    Kiniksa Pharmaceuticals International, plc

    Giant Cell Arteritis

    phase 2 other completed

    1 trial

  40. megestrol acetate oral suspension + serplulimab + SOX

    The First People's Hospital of Lianyungang

    Stage III Gastric Cancer

    phase 2 small molecule active

    1 trial

  41. meningococcal ACWY (vaccine)

    GlaxoSmithKline

    Infections, Meningococcal

    phase 2 mab completed

    1 trial

  42. mesenchymal stem cell

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Lupus Nephritis

    phase 2 mab active

    1 trial

  43. mesenchymal stem cell

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Kidney Transplant

    phase 2 mab active

    1 trial

  44. metformin

    BRIGHT MINDS BIOSCIENCES INC.

    Type 2 Diabetes

    phase 2 small molecule active

    1 trial

  45. metformin

    Takeda

    Type 2 Diabetes

    phase 2 small molecule completed

    1 trial

  46. methoxsalen

    Ultragenyx UK Limited

    Epidermolysis Bullosa Acquisita

    phase 2 small molecule completed

    1 trial

  47. methylprednisolone

    Teva Pharma GmbH

    Multiple Sclerosis (MS)

    phase 2 small molecule terminated

    1 trial

  48. middle-dose Norovirus Bivalent (GI.1 / GII.4) Vaccine

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Norovirus Infections

    phase 2 mab active

    1 trial

Frequently asked questions

How many Phase II pipeline programs are in the directory?

7,238 published programs match this development stage in our ClinicalTrials.gov index.

What defines this pipeline stage?

Phase and status reflect ClinicalTrials.gov registry fields at last sync. See our clinical trial phases reference for methodology.

Data attribution: Data sources · All pipeline programs

Drug approvals, clinical trials, M&A, event intelligence, and company updates — weekly.

Customize topics & region
Topics
Region

No spam. Unsubscribe anytime. See our privacy policy.