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Intelligence · Clinical Pipeline

Phase II Pipeline Programs

Proof-of-concept and dose-finding clinical programs in Phase II development.

Programs
7,238

Quick answer

NovaPharmaNews tracks 7,238 phase ii pharmaceutical pipeline programs from ClinicalTrials.gov. Proof-of-concept and dose-finding clinical programs in Phase II development.

Top sponsors

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  1. mipomersen

    IONIS PHARMACEUTICALS INC

    Metabolic Diseases

    phase 2 small molecule completed

    1 trial

  2. mirtazapine

    BRIGHT MINDS BIOSCIENCES INC.

    Substance Abuse

    phase 2 small molecule completed

    1 trial

  3. mitoxantrone hydrochloride liposome

    The First People's Hospital of Lianyungang

    Relapsed/Refractory Acute Myeloid Leukaemia

    phase 2 small molecule active

    2 trials

  4. mitoxantrone liposome 16 and azacitidine

    NovaBridge Biosciences

    Angioimmunoblastic T-cell Lymphoma

    phase 2 small molecule active

    1 trial

  5. monoclonal factor IX replacement therapy

    Ultragenyx UK Limited

    Hemophilia B

    phase 2 small molecule completed

    1 trial

  6. mucoid exopolysaccharide P. aeruginosa immune globulin IV

    Ultragenyx UK Limited

    Cystic Fibrosis

    phase 2 small molecule completed

    1 trial

  7. mutual support group

    Hong Kong Baptist University

    Schizophrenia

    phase 2 other completed

    1 trial

  8. nab-paclitaxel

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Breast Cancer

    phase 2 small molecule active

    1 trial

  9. nal-IRI /Experimental

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Metastatic Gastric Adenocarcinoma

    phase 2 small molecule active

    1 trial

  10. naltrexone implant

    BRIGHT MINDS BIOSCIENCES INC.

    Opioid Use Disorder

    phase 2 small molecule active

    2 trials

  11. nanoliposomal irinotecan

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Head & Neck Cancer

    phase 2 small molecule completed

    1 trial

  12. nanoparticle albumin-bound paclitaxel/carboplatin

    The First People's Hospital of Lianyungang

    Non-small Cell Lung Cancer

    phase 2 small molecule active

    1 trial

  13. nasogastric tube decompression

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Pancreaticoduodenectomy

    phase 2 other active

    1 trial

  14. nedaplatin

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Central Nervous System Tumors

    phase 2 small molecule active

    1 trial

  15. neoadjuvant anti-PD-1

    Shanghai Chest Hospital

    Esophageal Cancer

    phase 2 small molecule active

    1 trial

  16. neratinib

    PUMA BIOTECHNOLOGY, INC.

    HER2-mutant Non-Small Cell Lung Cancer

    phase 2 small molecule completed

    1 trial

  17. neratinib

    PUMA BIOTECHNOLOGY, INC.

    Breast Neoplasms

    phase 2 small molecule completed

    3 trials

  18. nerve growth factor

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Traumatic Brain Injury

    phase 2 small molecule completed

    1 trial

  19. nicotinamide

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Cutaneous Lupus Erythematosus

    phase 2 small molecule active

    1 trial

  20. nicotinamide adenine dinucleotid/nicotinamide mononucleotide

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Immune Thrombocytopenia

    phase 2 small molecule active

    1 trial

  21. nicotine transdermal system

    BRIGHT MINDS BIOSCIENCES INC.

    Smoking Cessation

    phase 2 small molecule completed

    1 trial

  22. nilotinib

    United Therapeutics Europe Ltd

    Mucosal Lentiginous Melanoma

    phase 2 small molecule completed

    1 trial

  23. nitric oxide gel

    Hospital Authority, Hong Kong

    Neuropathic Pain

    phase 2 small molecule completed

    1 trial

  24. nivolumab

    Bristol-Myers Squibb

    Neoplasms by Site

    phase 2 mab completed

    1 trial

  25. nivolumab, ipilimumab

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Hepatocellular Carcinoma (HCC)

    phase 2 small molecule completed

    1 trial

  26. non-preserved sterile liquid formulation

    Lacuna Pharma Pty Ltd

    Type 2 diabetes and Obesity

    phase 2 small molecule active

    1 trial

  27. octreotide

    Ultragenyx UK Limited

    Hereditary Hemorrhagic Telangiectasia

    phase 2 small molecule completed

    1 trial

  28. olmesartan medoxomil

    Daiichi Sankyo

    Chronic Glomerulonephritis

    phase 2 small molecule completed

    1 trial

  29. olsalazine

    Ultragenyx UK Limited

    Ankylosing Spondylitis

    phase 2 small molecule completed

    1 trial

  30. oncolytic adenovirus expressing GMCSF

    CG Oncology

    Bladder Cancer

    phase 2 mab terminated

    1 trial

  31. ondansetron

    The First People's Hospital of Lianyungang

    Hepatocellular Carcinoma (HCC)

    phase 2 small molecule active

    1 trial

  32. online adaptive radiotherapy

    The First People's Hospital of Lianyungang

    Cervical Cancer

    phase 2 other active

    1 trial

  33. open discectomy

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Lumbar Disc Herniation

    phase 2 other active

    1 trial

  34. opiates

    BRIGHT MINDS BIOSCIENCES INC.

    Heroin Dependence

    phase 2 small molecule completed

    1 trial

  35. oral treprostinil

    United Therapeutics Europe Ltd

    PAH

    phase 2 small molecule completed

    1 trial

  36. orelabrutinib combined with rituximab regimen

    The First People's Hospital of Lianyungang

    Marginal Zone Lymphoma(MZL)

    phase 2 small molecule active

    1 trial

  37. oritavancin

    Targanta Netherlands B.V.

    Staphylococcal Skin Infections

    phase 2 small molecule completed

    1 trial

  38. osimertinib

    AstraZeneca

    Carcinoma

    phase 2 small molecule active

    1 trial

  39. osimertinib mesylate tablets and anlotinib hydrochloride capsules

    The First People's Hospital of Lianyungang

    Non Small Cell Lung Cancer

    phase 2 small molecule terminated

    1 trial

  40. oxaliplatin

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Stomach Neoplasms

    phase 2 small molecule active

    1 trial

  41. oxaliplatin (OXA), levofolinate calcium (l-LV), 5-FU, panitumumab

    Takeda

    Colorectal Carcinoma

    phase 2 small molecule completed

    1 trial

  42. oxycodone 15 mg

    BRIGHT MINDS BIOSCIENCES INC.

    Opioid-Related Disorders

    phase 2 small molecule completed

    1 trial

  43. p.DOM-WT1-37 DNA Vaccine and p.DOM-WT1-126 DNA Vaccine

    INOVIO PHARMACEUTICALS, INC.

    Leukaemia (Acute)

    phase 2 mab completed

    1 trial

  44. pCAR-19B cells

    Chongqing Precision Biotech Co., Ltd

    Acute Lymphoblastic Leukemia

    phase 2 mab active

    2 trials

  45. pUMVC3-IGFBP2-HER2-IGF1R Plasmid DNA Vaccine

    United Therapeutics Europe Ltd

    Anatomic Stage I Breast Cancer AJCC v8

    phase 2 mab active

    1 trial

  46. paclitaxel/carboplatin/lapatinib

    Hospital Authority, Hong Kong

    ErbB2-Positive Stage I-III Breast Cancer

    phase 2 small molecule active

    1 trial

  47. palifosfamide

    Alaunos Therapeutics

    Adult Central Nervous System Germ Cell Tumor

    phase 2 small molecule terminated

    1 trial

  48. pallidotomy

    Ultragenyx UK Limited

    Parkinson Disease

    phase 2 other completed

    1 trial

Frequently asked questions

How many Phase II pipeline programs are in the directory?

7,238 published programs match this development stage in our ClinicalTrials.gov index.

What defines this pipeline stage?

Phase and status reflect ClinicalTrials.gov registry fields at last sync. See our clinical trial phases reference for methodology.

Data attribution: Data sources · All pipeline programs

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