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Intelligence · Clinical Pipeline

Phase II Pipeline Programs

Proof-of-concept and dose-finding clinical programs in Phase II development.

Programs
7,238

Quick answer

NovaPharmaNews tracks 7,238 phase ii pharmaceutical pipeline programs from ClinicalTrials.gov. Proof-of-concept and dose-finding clinical programs in Phase II development.

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  1. pandemic influenza vaccine (H5N1 strain NIBRG-14)

    Sinovac Research and Development Co.,

    Pandemic Influenza

    phase 2 mab completed

    1 trial

  2. pazopanib (GW786034)

    GlaxoSmithKline

    Neoplasms, Uterine Cervix

    phase 2 small molecule completed

    1 trial

  3. pazopanib (GW786034) 400 mg

    GlaxoSmithKline

    Neoplasms, Breast

    phase 2 small molecule completed

    1 trial

  4. pectin

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Crohn's Disease

    phase 2 small molecule terminated

    1 trial

  5. pegcrisantaspase

    Jazz Pharmaceuticals Ireland Limited

    Acute Lymphoblastic Leukemia

    phase 2 small molecule terminated

    1 trial

  6. peginesatide

    Takeda

    Anemia

    phase 2 small molecule completed

    5 trials

  7. pelareorep, Tecentriq 840 mg concentrate for solution for infusion

    ONCOLYTICS BIOTECH INC

    Patients with advanced or metastatic gastrointestinal (GI) tumors.

    phase 2 small molecule active

    1 trial

  8. pembrolizumab

    The University of Hong Kong

    T-Cell Lymphoma

    phase 2 small molecule active

    1 trial

  9. pembrolizumab

    Hospital Authority, Hong Kong

    Locally Recurrent Cancer

    phase 2 small molecule active

    1 trial

  10. pembrolizumab

    The First People's Hospital of Lianyungang

    Advanced Non-squamous Non-small-cell Lung Cancer

    phase 2 small molecule active

    1 trial

  11. pemetrexed

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Brain Metastases

    phase 2 small molecule active

    1 trial

  12. pemetrexed

    United Therapeutics Europe Ltd

    Lung Cancer

    phase 2 small molecule completed

    1 trial

  13. penpulimab, lenalidomide, Rituximab, Gemcitabine, Oxaliplatin

    The First People's Hospital of Lianyungang

    Lymphoma, Large B-Cell, Diffuse

    phase 2 small molecule active

    1 trial

  14. pepinemab + pembrolizumab

    VACCINEX, INC.

    Recurrent/Metastatic Squamous Cell Carcinoma of the Head and Neck (HNSCC)

    phase 2 small molecule completed

    1 trial

  15. perindopril arginine

    United Therapeutics Europe Ltd

    Abdominal Aortic Aneurysm

    phase 2 small molecule completed

    1 trial

  16. pharmorubicin or pirarubicin

    The First People's Hospital of Lianyungang

    Upper Tract Urothelial Carcinoma

    phase 2 small molecule active

    1 trial

  17. phosphate buffered saline., FX06

    Lacuna Pharma Pty Ltd

    Acute Respiratory Distress Syndrome (ARDS)

    phase 2 small molecule active

    1 trial

  18. phosphate-buffered saline for SC administration

    Alnylam Netherlands B.V.

    Hereditary Hemorrhagic Telangiectasia (HHT)

    phase 2 small molecule active

    1 trial

  19. pimozide

    Ultragenyx UK Limited

    Tourette Syndrome

    phase 2 small molecule completed

    1 trial

  20. pioglitazone

    Takeda

    Asthma

    phase 2 small molecule completed

    1 trial

  21. pioglitazone

    Takeda

    Alzheimer Disease

    phase 2 small molecule completed

    1 trial

  22. placebo

    Universal Integrated

    Postprandial Distress Syndrome

    phase 2 small molecule active

    1 trial

  23. placebo

    Nektar Therapeutics UK Limited

    Opioid Induced Constipation (OIC)

    phase 2 small molecule completed

    1 trial

  24. placebo

    The First People's Hospital of Lianyungang

    COVID-19 Thalidomide

    phase 2 small molecule active

    1 trial

  25. placebo PH20 SC PFS, Vyvgart 1 000 mg solution for injection in pre-filled syringe

    argenx

    Systemic Sclerosis

    phase 2 small molecule active

    1 trial

  26. placebo mouthwash

    BRIGHT MINDS BIOSCIENCES INC.

    Dentinal Hypersensitivity

    phase 2 other completed

    1 trial

  27. placebo of BAY 3427080, BAY 3427080

    Bayer AG

    Sleep disturbances associated with menopause

    phase 2 small molecule active

    1 trial

  28. plain crystalline niacin, exercise, sauna

    United Therapeutics Europe Ltd

    Gulf War Illness

    phase 2 small molecule completed

    1 trial

  29. pneumococcal polysaccharide and protein conjugate vaccines

    United Therapeutics Europe Ltd

    Pneumococcal Infections

    phase 2 mab completed

    1 trial

  30. ponatinib - Phase 1

    Takeda

    Chronic Myeloid Leukemia (CML)

    phase 2 small molecule completed

    1 trial

  31. pregabalin

    United Therapeutics Europe Ltd

    Pain

    phase 2 small molecule completed

    1 trial

  32. pyrotinib and trastuzumab in combinition with neoadjuvant chemotherapy

    The First People's Hospital of Lianyungang

    HER2-positive Breast Cancer

    phase 2 small molecule active

    1 trial

  33. rAAV9.CMV.hNAGLU

    ABEONA THERAPEUTICS INC.

    Mucopolysaccharidosis Type 3 B

    phase 2 mab terminated

    1 trial

  34. rAvPAL-PEG

    BioMarin Pharmaceutical Australia Pty Ltd

    Phenylketonuria

    phase 2 small molecule completed

    3 trials

  35. rAvPAL-PEG 0.001 mg/kg

    BioMarin Pharmaceutical Australia Pty Ltd

    Phenylketonuria

    phase 2 small molecule completed

    1 trial

  36. rF1V-1018

    United Therapeutics Europe Ltd

    Prevention of Pneumonic Plague Resulting From Aerosol Exposure to Yersenia Pestis

    phase 2 mab active

    1 trial

  37. rF1V-1018

    United Therapeutics Europe Ltd

    Plague, Pneumonic

    phase 2 mab completed

    1 trial

  38. rHuPH20

    HALOZYME THERAPEUTICS, INC.

    Dermatitis, Allergic Contact

    phase 2 small molecule completed

    1 trial

  39. rTMS (repetitive transcranial magnetic stimulation)

    CNS Pharmaceuticals

    Obsessive-Compulsive Disorder

    phase 2 other active

    1 trial

  40. rVA576

    Akari Therapeutics Plc

    Bullous Pemphigoid (BP)

    phase 2 small molecule completed

    1 trial

  41. rVA576

    Akari Therapeutics Plc

    Keratoconjunctivitis, Atopic

    phase 2 small molecule terminated

    1 trial

  42. rabbit ATG, Cyclosporine, Levamisole

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Aplastic Anemia

    phase 2 small molecule completed

    1 trial

  43. radiation therapy

    Children's Hospital of Fudan University

    Brain Tumor

    phase 2 other completed

    1 trial

  44. raltitrexed combined with apatinib

    Chinese PLA General Hospital

    Colorectal Cancer

    phase 2 small molecule active

    1 trial

  45. ranibizumab

    CUMBERLAND PHARMACEUTICALS INC

    Retinal Vein Occlusion

    phase 2 small molecule completed

    1 trial

  46. rapcabtagene autoleucel

    Novartis Pharmaceuticals

    Scleroderma, Diffuse

    phase 2 mab active

    1 trial

  47. rasagiline mesylate

    Teva Pharma GmbH

    Multiple System Atrophy

    phase 2 small molecule completed

    1 trial

  48. real-tDCS with MI-BCI

    Hospital Authority, Hong Kong

    Stroke

    phase 2 other completed

    1 trial

Frequently asked questions

How many Phase II pipeline programs are in the directory?

7,238 published programs match this development stage in our ClinicalTrials.gov index.

What defines this pipeline stage?

Phase and status reflect ClinicalTrials.gov registry fields at last sync. See our clinical trial phases reference for methodology.

Data attribution: Data sources · All pipeline programs

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