Friday, July 10, 2026
🇺🇸 FDA

Intelligence · Clinical pipeline

Phase II Pipeline Programs

Proof-of-concept and dose-finding clinical programs in Phase II development.

Programs 7,238
Sponsors 1,771
Drugs 4,798

Quick answer

NovaPharmaNews tracks 7,238 phase ii pharmaceutical pipeline programs from ClinicalTrials.gov. Proof-of-concept and dose-finding clinical programs in Phase II development.

Top sponsors

Pipeline programs

Page 147 of 151

  1. lymphokine-activated killer cells

    LISATA THERAPEUTICS, INC.

    Brain and Central Nervous System Tumors

    phase 2 mab terminated

    1 trial

  2. mFOLFOX6 + BIBF 1120

    Galmed Pharmaceuticals

    Colorectal Cancer

    phase 2 small molecule completed

    1 trial

  3. mFOLFOXIRI

    The First People's Hospital of Lianyungang

    Locally Advanced Rectal Cancer

    phase 2 small molecule active

    1 trial

  4. mRNA 3210-P101

    Moderna Biotech Spain

    Participants with Phenylketonuria

    phase 2 small molecule active

    1 trial

  5. mRNA-3745-P102

    Moderna Biotech Spain

    Glycogen storage disease type 1a (GSD1a)

    phase 2 small molecule active

    1 trial

  6. mRNA-3927

    Moderna Biotech Spain

    Propionic Acidemia

    phase 2 small molecule active

    1 trial

  7. mRNA-3927-P101

    Moderna Biotech Spain

    Propionic Acidemia

    phase 2 small molecule active

    1 trial

  8. mRNA-4157, BCG VACCINE

    Merck Sharp and Dohme

    Bladder cancer

    phase 2 small molecule active

    1 trial

  9. mavrilimumab

    Kiniksa Pharmaceuticals International, plc

    Giant Cell Arteritis

    phase 2 other completed

    1 trial

  10. megestrol acetate oral suspension + serplulimab + SOX

    The First People's Hospital of Lianyungang

    Stage III Gastric Cancer

    phase 2 small molecule active

    1 trial

  11. meningococcal ACWY (vaccine)

    GlaxoSmithKline

    Infections, Meningococcal

    phase 2 mab completed

    1 trial

  12. mesenchymal stem cell

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Kidney Transplant

    phase 2 mab active

    1 trial

  13. mesenchymal stem cell

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Lupus Nephritis

    phase 2 mab active

    1 trial

  14. metformin

    BRIGHT MINDS BIOSCIENCES INC.

    Type 2 Diabetes

    phase 2 small molecule active

    1 trial

  15. metformin

    Takeda

    Type 2 Diabetes

    phase 2 small molecule completed

    1 trial

  16. methoxsalen

    Ultragenyx UK Limited

    Epidermolysis Bullosa Acquisita

    phase 2 small molecule completed

    1 trial

  17. methylprednisolone

    Teva Pharma GmbH

    Multiple Sclerosis (MS)

    phase 2 small molecule terminated

    1 trial

  18. middle-dose Norovirus Bivalent (GI.1 / GII.4) Vaccine

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Norovirus Infections

    phase 2 mab active

    1 trial

  19. mipomersen

    IONIS PHARMACEUTICALS INC

    Metabolic Diseases

    phase 2 small molecule completed

    1 trial

  20. mirtazapine

    BRIGHT MINDS BIOSCIENCES INC.

    Substance Abuse

    phase 2 small molecule completed

    1 trial

  21. mitoxantrone hydrochloride liposome

    The First People's Hospital of Lianyungang

    Relapsed/Refractory Acute Myeloid Leukaemia

    phase 2 small molecule active

    2 trials

  22. mitoxantrone liposome 16 and azacitidine

    NovaBridge Biosciences

    Angioimmunoblastic T-cell Lymphoma

    phase 2 small molecule active

    1 trial

  23. monoclonal factor IX replacement therapy

    Ultragenyx UK Limited

    Hemophilia B

    phase 2 small molecule completed

    1 trial

  24. mucoid exopolysaccharide P. aeruginosa immune globulin IV

    Ultragenyx UK Limited

    Cystic Fibrosis

    phase 2 small molecule completed

    1 trial

  25. mutual support group

    Hong Kong Baptist University

    Schizophrenia

    phase 2 other completed

    1 trial

  26. nab-paclitaxel

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Breast Cancer

    phase 2 small molecule active

    1 trial

  27. nal-IRI /Experimental

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Metastatic Gastric Adenocarcinoma

    phase 2 small molecule active

    1 trial

  28. naltrexone implant

    BRIGHT MINDS BIOSCIENCES INC.

    Opioid Use Disorder

    phase 2 small molecule active

    2 trials

  29. nanoliposomal irinotecan

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Head & Neck Cancer

    phase 2 small molecule completed

    1 trial

  30. nanoparticle albumin-bound paclitaxel/carboplatin

    The First People's Hospital of Lianyungang

    Non-small Cell Lung Cancer

    phase 2 small molecule active

    1 trial

  31. nasogastric tube decompression

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Pancreaticoduodenectomy

    phase 2 other active

    1 trial

  32. nedaplatin

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Central Nervous System Tumors

    phase 2 small molecule active

    1 trial

  33. neoadjuvant anti-PD-1

    Shanghai Chest Hospital

    Esophageal Cancer

    phase 2 small molecule active

    1 trial

  34. neratinib

    PUMA BIOTECHNOLOGY, INC.

    Breast Neoplasms

    phase 2 small molecule completed

    3 trials

  35. neratinib

    PUMA BIOTECHNOLOGY, INC.

    HER2-mutant Non-Small Cell Lung Cancer

    phase 2 small molecule completed

    1 trial

  36. nerve growth factor

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Traumatic Brain Injury

    phase 2 small molecule completed

    1 trial

  37. nicotinamide

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Cutaneous Lupus Erythematosus

    phase 2 small molecule active

    1 trial

  38. nicotinamide adenine dinucleotid/nicotinamide mononucleotide

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Immune Thrombocytopenia

    phase 2 small molecule active

    1 trial

  39. nicotine transdermal system

    BRIGHT MINDS BIOSCIENCES INC.

    Smoking Cessation

    phase 2 small molecule completed

    1 trial

  40. nilotinib

    United Therapeutics Europe Ltd

    Mucosal Lentiginous Melanoma

    phase 2 small molecule completed

    1 trial

  41. nitric oxide gel

    Hospital Authority, Hong Kong

    Neuropathic Pain

    phase 2 small molecule completed

    1 trial

  42. nivolumab

    Bristol-Myers Squibb

    Neoplasms by Site

    phase 2 mab completed

    1 trial

  43. nivolumab, ipilimumab

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Hepatocellular Carcinoma (HCC)

    phase 2 small molecule completed

    1 trial

  44. non-preserved sterile liquid formulation

    Lacuna Pharma Pty Ltd

    Type 2 diabetes and Obesity

    phase 2 small molecule active

    1 trial

  45. octreotide

    Ultragenyx UK Limited

    Hereditary Hemorrhagic Telangiectasia

    phase 2 small molecule completed

    1 trial

  46. olmesartan medoxomil

    Daiichi Sankyo

    Chronic Glomerulonephritis

    phase 2 small molecule completed

    1 trial

  47. olsalazine

    Ultragenyx UK Limited

    Ankylosing Spondylitis

    phase 2 small molecule completed

    1 trial

  48. oncolytic adenovirus expressing GMCSF

    CG Oncology

    Bladder Cancer

    phase 2 mab terminated

    1 trial

Frequently asked questions

How many Phase II pipeline programs are in the directory?

7,238 published programs match this development stage in our ClinicalTrials.gov index.

What defines this pipeline stage?

Phase and status reflect ClinicalTrials.gov registry fields at last sync. See our clinical trial phases reference for methodology.

Drug approvals, clinical trials, M&A, event intelligence, and company updates — weekly.

Customize topics & region
Topics
Region

No spam. Unsubscribe anytime. See our privacy policy.