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Intelligence · Clinical pipeline

Phase II Pipeline Programs

Proof-of-concept and dose-finding clinical programs in Phase II development.

Programs 7,238
Sponsors 1,771
Drugs 4,798

Quick answer

NovaPharmaNews tracks 7,238 phase ii pharmaceutical pipeline programs from ClinicalTrials.gov. Proof-of-concept and dose-finding clinical programs in Phase II development.

Top sponsors

Pipeline programs

Page 146 of 151

  1. heme arginate

    Ultragenyx UK Limited

    Porphyria

    phase 2 small molecule completed

    3 trials

  2. honeybee venom (Apitoxin (Korea) Apitox (USA))

    Apimeds Pharmaceuticals US

    Osteoarthritis of the Knee

    phase 2 small molecule completed

    1 trial

  3. hydrocortisone

    Ultragenyx UK Limited

    Bronchopulmonary Dysplasia

    phase 2 small molecule completed

    1 trial

  4. hyperbaric oxygen

    United Therapeutics Europe Ltd

    Breast Cancer

    phase 2 small molecule active

    1 trial

  5. iCasp9M28z T cell infusions

    United Therapeutics Europe Ltd

    Malignant Pleural Disease

    phase 2 gene therapy active

    1 trial

  6. idecabtagene vicleucel

    Celgene Europe Limited

    Relapsed and refractory multiple myeloma (RRMM), multiple myeloma (MM) with progression within 18 months of initial treatment/ or newly diagnosed multiple myeloma (NDMM) with suboptimal response post autologous stem cell transplant (ASCT) (Cohort 3 only)

    phase 2 small molecule active

    1 trial

  7. iloperidone

    Vanda Pharmaceuticals Netherlands B.V.

    Hypertension

    phase 2 small molecule active

    1 trial

  8. imvotamab

    ADC Therapeutics SA

    Non-Hodgkin Lymphoma

    phase 2 small molecule terminated

    1 trial

  9. indibulin

    Alaunos Therapeutics

    Advanced Solid Tumors

    phase 2 small molecule active

    2 trials

  10. induction chemotherapy and immunotherapy

    The First People's Hospital of Lianyungang

    ESCC

    phase 2 small molecule completed

    1 trial

  11. infliximab (Remicade)

    Universal Integrated

    COPD

    phase 2 small molecule completed

    1 trial

  12. infloran

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Enterocolitis, Necrotizing

    phase 2 other terminated

    1 trial

  13. infusion of MYOCET

    Teva Pharma GmbH

    Cerebral Lymphoma B Cell Refractory

    phase 2 small molecule terminated

    1 trial

  14. inhaled delta-8-THC 300mcg or 600mcg per dose

    Teva Pharma GmbH

    Cancer

    phase 2 small molecule terminated

    1 trial

  15. interleukin-4 PE38KDEL cytotoxin

    NEUROCRINE BIOSCIENCES INC

    Brain and Central Nervous System Tumors

    phase 2 mab completed

    1 trial

  16. intravenous infusion (IV) of Adebrelimab (ADE)

    The First People's Hospital of Lianyungang

    Advanced Hepatocellular Carcinoma (HCC)

    phase 2 small molecule active

    1 trial

  17. ipatasertib

    United Therapeutics Europe Ltd

    Solid Tumor

    phase 2 small molecule active

    1 trial

  18. irbesartan

    LIGAND PHARMACEUTICALS INC

    Hypertension

    phase 2 small molecule completed

    1 trial

  19. irradiation

    Ultragenyx UK Limited

    Brain Neoplasms

    phase 2 other active

    1 trial

  20. itraconazole

    Ultragenyx UK Limited

    Histoplasmosis

    phase 2 small molecule completed

    1 trial

  21. iv ibuprofen

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Extremely Premature Infants

    phase 2 small molecule active

    1 trial

  22. ivonescimab

    CERO THERAPEUTICS HOLDINGS, INC.

    pleural mesothelioma

    phase 2 small molecule active

    1 trial

  23. ivosidenib and nivolumab

    Agios Netherlands B.V.

    Advanced Solid Tumor

    phase 2 small molecule completed

    1 trial

  24. killed oral cholera vaccine

    International Peace Maternity and Child Health Hospital

    Cholera

    phase 2 mab completed

    1 trial

  25. l-tetrahydropalmatine (l-THP)

    BRIGHT MINDS BIOSCIENCES INC.

    Cocaine Use

    phase 2 small molecule terminated

    1 trial

  26. lactulose

    Ultragenyx UK Limited

    Portal Hypertension

    phase 2 small molecule completed

    1 trial

  27. lanadelumab

    Takeda

    COVID-19

    phase 2 mab completed

    1 trial

  28. laquinimod 0.3

    Teva Pharma GmbH

    Relapsing Remitting Multiple Sclerosis

    phase 2 small molecule completed

    1 trial

  29. lenalidomide combined with rituximab

    The First People's Hospital of Lianyungang

    Diffuse Large B Cell Lymphoma

    phase 2 small molecule active

    1 trial

  30. lestaurtinib

    Teva Pharma GmbH

    Polycythemia Vera

    phase 2 small molecule completed

    1 trial

  31. leucovorin+5-FU

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Colonic Diseases

    phase 2 small molecule active

    1 trial

  32. leuprolide

    Ultragenyx UK Limited

    Spinal Muscular Atrophy

    phase 2 small molecule completed

    1 trial

  33. leuprolide

    Ultragenyx UK Limited

    Hyperandrogenism

    phase 2 small molecule completed

    1 trial

  34. leuprolide acetate

    Ultragenyx UK Limited

    Acanthosis Nigricans

    phase 2 small molecule completed

    1 trial

  35. levamisole

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Anemia

    phase 2 small molecule active

    1 trial

  36. levetiracetam

    BRIGHT MINDS BIOSCIENCES INC.

    Cocaine Dependence

    phase 2 small molecule completed

    2 trials

  37. levodopa

    BRIGHT MINDS BIOSCIENCES INC.

    Cocaine Dependence

    phase 2 small molecule completed

    1 trial

  38. levodopa

    United Therapeutics Europe Ltd

    Parkinson Disease

    phase 2 small molecule completed

    1 trial

  39. levothyroxine sodium

    Xeris Biopharma Holdings

    Hypothyroidism

    phase 2 small molecule completed

    1 trial

  40. linaclotide acetate

    IRONWOOD PHARMACEUTICALS INC

    Chronic Constipation

    phase 2 small molecule completed

    1 trial

  41. linagliptin low dose

    Boehringer Ingelheim

    Diabetes Mellitus, Type 2

    phase 2 small molecule completed

    1 trial

  42. lisdexamfetamine dimesylate (SPD489)

    Takeda

    Binge Eating Disorder

    phase 2 small molecule completed

    1 trial

  43. lorcaserin

    BRIGHT MINDS BIOSCIENCES INC.

    Nicotine Dependence

    phase 2 small molecule completed

    1 trial

  44. lotilaner

    Tarsus Pharmaceuticals

    Ocular Rosacea

    phase 2 small molecule active

    1 trial

  45. low-dose Recombinant SARS-CoV-2 Vaccine (CHO cell)

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    COVID-19

    phase 2 mab completed

    1 trial

  46. low-dose lymphocyte immunotherapy

    Nanjing Zenshine Pharmaceuticals

    Unexplained Recurrent Miscarriage and Recurrent Implantation Failure

    phase 2 other completed

    1 trial

  47. lurbinectedin for Advanced/Recurrent Endometrial…

    The George Institute

    Advanced/Recurrent Endometrial Cancer Patients with Disease Progression after Prior Therapy with Platinum-based Chemotherapy

    phase 2 small molecule active

    1 trial

  48. lymphocyte gene therapy

    Ultragenyx UK Limited

    Mucopolysaccharidosis II

    phase 2 gene therapy completed

    1 trial

Frequently asked questions

How many Phase II pipeline programs are in the directory?

7,238 published programs match this development stage in our ClinicalTrials.gov index.

What defines this pipeline stage?

Phase and status reflect ClinicalTrials.gov registry fields at last sync. See our clinical trial phases reference for methodology.

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