Friday, July 10, 2026

Intelligence · Clinical pipeline

Phase II Pipeline Programs

Proof-of-concept and dose-finding clinical programs in Phase II development.

Programs 7,238
Sponsors 1,771
Drugs 4,798

Quick answer

NovaPharmaNews tracks 7,238 phase ii pharmaceutical pipeline programs from ClinicalTrials.gov. Proof-of-concept and dose-finding clinical programs in Phase II development.

Top sponsors

Pipeline programs

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  1. entinostat

    Syndax Pharmaceuticals

    Epithelial Ovarian Cancer

    phase 2 small molecule completed

    1 trial
  2. entinostat

    Syndax Pharmaceuticals

    Breast Cancer

    phase 2 small molecule completed

    4 trials
  3. entinostat

    Syndax Pharmaceuticals

    Estrogen Receptor-negative Breast Cancer

    phase 2 small molecule terminated

    1 trial
  4. eribulin mesylate + erlotinib

    Eisai Co.,

    Non-small Cell Lung Cancer

    phase 2 small molecule completed

    1 trial
  5. erlotinib [Tarceva]

    Hoffmann-La Roche

    Non-Small Cell Lung Cancer

    phase 2 small molecule completed

    1 trial
  6. erlotinib and bexarotene

    LIGAND PHARMACEUTICALS INC

    Carcinoma, Non-small-cell Lung

    phase 2 small molecule completed

    1 trial
  7. escitalopram

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Addiction

    phase 2 small molecule terminated

    1 trial
  8. etavopivat B 10041, etavopivat B 10042

    NovoThirteen

    Sickle Cell Disease

    phase 2 small molecule active

    1 trial
  9. etiprednol dicloacetate

    Teva Pharma GmbH

    Crohn's Disease

    phase 2 small molecule completed

    1 trial
  10. etrasimod

    MAIA Biotechnology

    Pouchitis

    phase 2 small molecule active

    1 trial
  11. everolimus

    United Therapeutics Europe Ltd

    Malignant Peripheral Nerve Sheath Tumors

    phase 2 small molecule completed

    1 trial
  12. evinacumab

    Regeneron UK Limited

    Severe Hypertriglyceridemia (sHTG)

    phase 2 small molecule completed

    1 trial
  13. evinacumab

    Regeneron UK Limited

    Hypertriglyceridemia

    phase 2 small molecule terminated

    1 trial
  14. evorpacept

    ALX ONCOLOGY HOLDINGS INC

    Head and Neck Cancer

    phase 2 small molecule active

    2 trials
  15. experimental group x-MAP

    The First People's Hospital of Lianyungang

    Metastatic Colorectal Cancer (mCRC)

    phase 2 other active

    1 trial
  16. extended-release buprenorphine (BXR)

    BRIGHT MINDS BIOSCIENCES INC.

    Opioid-use Disorder

    phase 2 small molecule on hold

    1 trial
  17. farletuzumab ecteribulin

    Bristol-Myers Squibb Australia Pty Ltd

    Metastatic Non-Small Cell Lung Cancer

    phase 2 small molecule active

    1 trial
  18. fecal microbiota

    The First People's Hospital of Lianyungang

    Insomnia Chronic

    phase 2 mab completed

    1 trial
  19. fetal nigral transplantation

    Ultragenyx UK Limited

    Parkinson Disease

    phase 2 other completed

    1 trial
  20. filgrastim

    Ultragenyx UK Limited

    Shwachman Syndrome

    phase 2 small molecule completed

    1 trial
  21. fluconazole

    Ultragenyx UK Limited

    Sporotrichosis

    phase 2 small molecule completed

    1 trial
  22. fluconazole

    Ultragenyx UK Limited

    Histoplasmosis

    phase 2 small molecule completed

    1 trial
  23. forodesine HCl

    Biocryst

    Chronic Lymphocytic Leukemia (CLL)

    phase 2 small molecule completed

    1 trial
  24. forodesine hydrochloride

    Biocryst

    Lymphoma

    phase 2 small molecule completed

    2 trials
  25. forodesine hydrochloride (BCX-1777)

    Biocryst

    Leukemia, T-Cell

    phase 2 small molecule completed

    1 trial
  26. forodesine hydrochloride (BCX-1777)

    Biocryst

    Leukemia, Lymphocytic, Chronic

    phase 2 small molecule completed

    1 trial
  27. forodesine hydrochloride (BCX-1777)

    Biocryst

    B-cell Acute Lymphoblastic Leukemia

    phase 2 small molecule completed

    1 trial
  28. fostamatinib

    RIGEL PHARMACEUTICALS INC

    Lymphoma

    phase 2 small molecule completed

    1 trial
  29. fremanezumab

    Teva Pharma GmbH

    Interstitial Cystitis

    phase 2 small molecule terminated

    1 trial
  30. fruquintinib

    Takeda

    Colon Cancer

    phase 2 small molecule active

    1 trial
  31. fulzerasib

    The First People's Hospital of Lianyungang

    Resectable NSCLC

    phase 2 small molecule active

    1 trial
  32. furmonertinib

    Sun Yat-sen University

    Non-small Cell Lung Cancer Metastatic

    phase 2 small molecule completed

    1 trial
  33. ganetespib

    United Therapeutics Europe Ltd

    Malignant Peripheral Nerve Sheath Tumors (MPNST)

    phase 2 small molecule completed

    1 trial
  34. gemcitabine

    Yung NA

    Muscle Invasive Bladder Urothelial Carcinoma

    phase 2 small molecule active

    1 trial
  35. gemcitabine and cisplatin

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Nasopharyngeal Squamous Cell Carcinoma

    phase 2 small molecule completed

    1 trial
  36. gemcitabine and oxaliplatin.

    The First People's Hospital of Lianyungang

    Gallbladder Carcinoma

    phase 2 small molecule active

    1 trial
  37. gene therapy

    PTC THERAPEUTICS, INC.

    Aromatic L-amino Acid Decarboxylase (AADC) Deficiency

    phase 2 small molecule completed

    1 trial
  38. genexolPM + cisplatin

    Solid Biosciences

    Locally Advanced Head and Neck Squamous Cell Carcinoma

    phase 2 small molecule completed

    1 trial
  39. glatiramer acetate

    Teva Pharma GmbH

    Crohns Disease

    phase 2 small molecule active

    1 trial
  40. glatiramer acetate 20 mg

    Teva Pharma GmbH

    Relapsing Remitting Multiple Sclerosis

    phase 2 small molecule completed

    1 trial
  41. glatiramer acetate 20 mg

    Teva Pharma GmbH

    Relapse-Remitting Multiple Sclerosis

    phase 2 small molecule completed

    1 trial
  42. glatiramer acetate with minocycline

    Teva Pharma GmbH

    Relapse Remitting Multiple Sclerosis

    phase 2 small molecule completed

    1 trial
  43. glucagon

    Xeris Biopharma Holdings

    Post-bariatric Hypoglycemia

    phase 2 small molecule completed

    1 trial
  44. golexanolone

    COGNITION THERAPEUTICS INC

    Primary Biliary Cholangitis (PBC)

    phase 2 small molecule active

    1 trial
  45. golidocitinib

    The First People's Hospital of Lianyungang

    IrAE

    phase 2 small molecule active

    1 trial
  46. growth hormone

    Ultragenyx UK Limited

    Turner's Syndrome

    phase 2 small molecule completed

    1 trial
  47. growth hormone

    Ultragenyx UK Limited

    Cystic Fibrosis

    phase 2 small molecule completed

    1 trial
  48. guanfacine-ER

    BRIGHT MINDS BIOSCIENCES INC.

    Cannabis Use

    phase 2 small molecule completed

    1 trial

Frequently asked questions

How many Phase II pipeline programs are in the directory?

7,238 published programs match this development stage in our ClinicalTrials.gov index.

What defines this pipeline stage?

Phase and status reflect ClinicalTrials.gov registry fields at last sync. See our clinical trial phases reference for methodology.