Friday, July 10, 2026

Intelligence · Clinical pipeline

Phase II Pipeline Programs

Proof-of-concept and dose-finding clinical programs in Phase II development.

Programs 7,238
Sponsors 1,771
Drugs 4,798

Quick answer

NovaPharmaNews tracks 7,238 phase ii pharmaceutical pipeline programs from ClinicalTrials.gov. Proof-of-concept and dose-finding clinical programs in Phase II development.

Top sponsors

Pipeline programs

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  1. clarithromycin

    BRIGHT MINDS BIOSCIENCES INC.

    Relapse/Refractory Multiple Myeloma

    phase 2 small molecule terminated

    1 trial
  2. coformulated emtricitabine (FTC) and tenofovir disoproxil fumarate (TDF) as PrEP

    BRIGHT MINDS BIOSCIENCES INC.

    HIV

    phase 2 small molecule completed

    1 trial
  3. combination with Disitamab Vedotin and with Tislelizumab and Capecitabine

    Hospital Authority, Hong Kong

    Gastric Cancer

    phase 2 small molecule active

    1 trial
  4. compound diclofenac sodium

    The First People's Hospital of Lianyungang

    Acute Abdominal Pain

    phase 2 small molecule active

    1 trial
  5. conivaptan

    CUMBERLAND PHARMACEUTICALS INC

    Liver Cirrhosis

    phase 2 small molecule completed

    1 trial
  6. conivaptan

    CUMBERLAND PHARMACEUTICALS INC

    Chronic Heart Failure

    phase 2 small molecule completed

    1 trial
  7. controlled release carvedilol

    BRIGHT MINDS BIOSCIENCES INC.

    Cocaine Dependence

    phase 2 small molecule completed

    1 trial
  8. convention therapy

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Stroke

    phase 2 small molecule completed

    1 trial
  9. conventional therapy plus low dose hUC-MSCs treatment

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Liver Cirrhosis

    phase 2 mab completed

    1 trial
  10. corticosteroids

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Acute Severe Colitis (ASC)

    phase 2 small molecule active

    1 trial
  11. corticosteroids combined with immunoglobulin and romiplostim

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Primary Immune Thrombocytopenia

    phase 2 small molecule active

    1 trial
  12. cyclophosphamide

    Ultragenyx UK Limited

    Pemphigus

    phase 2 small molecule completed

    1 trial
  13. cyclophosphamide

    Ultragenyx UK Limited

    Anemia, Hemolytic, Autoimmune

    phase 2 small molecule completed

    1 trial
  14. cyclosporine

    Ultragenyx UK Limited

    Sickle Cell Anemia

    phase 2 small molecule completed

    1 trial
  15. cyclosporine (reduced exposure) / everolimus

    Novartis Pharmaceuticals

    Kidney Transplantation

    phase 2 small molecule completed

    1 trial
  16. cytarabine

    Teva Pharma GmbH

    Acute Myeloid Leukemia With Multilineage Dysplasia Following Myelodysplastic Syndrome

    phase 2 small molecule terminated

    1 trial
  17. cytarabine

    Ultragenyx UK Limited

    Lupus Erythematosus, Systemic

    phase 2 small molecule completed

    1 trial
  18. d-cycloserine

    BRIGHT MINDS BIOSCIENCES INC.

    Panic Disorder

    phase 2 small molecule completed

    1 trial
  19. d-cycloserine

    BRIGHT MINDS BIOSCIENCES INC.

    COCAINE-RELATED DISORDERS

    phase 2 small molecule completed

    1 trial
  20. dabrafenib

    GlaxoSmithKline

    Solid Tumours

    phase 2 small molecule completed

    1 trial
  21. dapagliflozin

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Acute Kidney Injury

    phase 2 small molecule active

    1 trial
  22. deferoxamine

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Intracerebral Hemorrhage

    phase 2 small molecule active

    1 trial
  23. delandistrogene moxeparvovec

    Sarepta Therapeutics

    Muscular Dystrophy, Duchenne

    phase 2 gene therapy active

    2 trials
  24. delolimogene mupadenorepvec

    Chongqing Precision Biotech Co., Ltd

    Malignant Melanoma

    phase 2 gene therapy completed

    1 trial
  25. denileukin diftitox

    LIGAND PHARMACEUTICALS INC

    Drug/Agent Toxicity by Tissue/Organ

    phase 2 mab completed

    1 trial
  26. desogestrel/ethinyl estradiol and ethinyl estradiol

    Teva Pharma GmbH

    Hemostasis

    phase 2 small molecule completed

    1 trial
  27. disitamab vedotin

    Pfizer

    Urothelial Carcinoma

    phase 2 small molecule active

    1 trial
  28. docetaxel

    Sanofi Pasteur

    Nasopharyngeal Neoplasms

    phase 2 small molecule completed

    1 trial
  29. docetaxel and ketoconazole

    Hospital Authority, Hong Kong

    Metastatic Breast Cancer

    phase 2 small molecule completed

    1 trial
  30. docetaxel+CDDP

    Solid Biosciences

    Head and Neck Squamous Cell Carcinoma

    phase 2 small molecule terminated

    1 trial
  31. donepezil

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Cognitive Impairment

    phase 2 small molecule active

    1 trial
  32. donor-derived NK cell infusion

    Chongqing Precision Biotech Co., Ltd

    Non-small Cell Lung Cancer

    phase 2 mab active

    1 trial
  33. dovitinib lactate

    United Therapeutics Europe Ltd

    Gastrinoma

    phase 2 small molecule terminated

    1 trial
  34. doxorubicin, docetaxel

    Hospital Authority, Hong Kong

    Metastatic Breast Cancer

    phase 2 small molecule completed

    1 trial
  35. dronabinol

    BRIGHT MINDS BIOSCIENCES INC.

    HIV Infections

    phase 2 small molecule completed

    1 trial
  36. dupilumab

    Regeneron UK Limited

    Allergic Bronchopulmonary Aspergillosis

    phase 2 small molecule completed

    1 trial
  37. dupilumab

    Regeneron UK Limited

    Chronic Sinusitis

    phase 2 mab completed

    1 trial
  38. e-cigarette

    BRIGHT MINDS BIOSCIENCES INC.

    Nontherapeutic

    phase 2 other completed

    1 trial
  39. ecallantide 60 mg

    Takeda

    ACE Inhibitor Induced Angioedema

    phase 2 small molecule terminated

    1 trial
  40. edratide

    Teva Pharma GmbH

    Systemic Lupus Erythematosus

    phase 2 small molecule terminated

    1 trial
  41. electroacupuncture group

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Urinary Stress Incontinence

    phase 2 other completed

    1 trial
  42. elritercept

    Takeda

    Anemia in Patients with Very Low, Low, or Intermediate Risk Myelodysplastic Syndromes (MDS).

    phase 2 small molecule active

    1 trial
  43. eltrombopag

    Novartis Pharmaceuticals

    Thrombocytopaenia

    phase 2 small molecule completed

    1 trial
  44. employment-based reinforcement

    BRIGHT MINDS BIOSCIENCES INC.

    Opiate Dependence

    phase 2 other completed

    1 trial
  45. empowerment theory-based small group discussion

    BRIGHT MINDS BIOSCIENCES INC.

    HIV Infection

    phase 2 other completed

    1 trial
  46. emtricitabine/tenofovir alafenamide

    United Therapeutics Europe Ltd

    Acceptability of Health Care

    phase 2 small molecule completed

    1 trial
  47. enalapril

    Ultragenyx UK Limited

    Pseudohypoaldosteronism

    phase 2 small molecule completed

    1 trial
  48. encaleret

    BridgeBio Oncology Therapeutics

    Post-Surgical Hypoparathyroidism

    phase 2 small molecule completed

    1 trial

Frequently asked questions

How many Phase II pipeline programs are in the directory?

7,238 published programs match this development stage in our ClinicalTrials.gov index.

What defines this pipeline stage?

Phase and status reflect ClinicalTrials.gov registry fields at last sync. See our clinical trial phases reference for methodology.