Friday, July 10, 2026

Intelligence · Clinical pipeline

Phase II Pipeline Programs

Proof-of-concept and dose-finding clinical programs in Phase II development.

Programs 7,238
Sponsors 1,771
Drugs 4,798

Quick answer

NovaPharmaNews tracks 7,238 phase ii pharmaceutical pipeline programs from ClinicalTrials.gov. Proof-of-concept and dose-finding clinical programs in Phase II development.

Top sponsors

Pipeline programs

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  1. amobarbital/Gel-One (one dose)

    United Therapeutics Europe Ltd

    Osteoarthritis

    phase 2 small molecule completed

    1 trial
  2. anagrelide hydrochloride

    Takeda

    Essential Thrombocythaemia

    phase 2 small molecule completed

    1 trial
  3. anastrozole

    Atrium Therapeutics

    Female Breast Carcinoma

    phase 2 small molecule active

    1 trial
  4. anlotinib

    Fudan University

    Extensive-stage Small Cell Lung Cancer

    phase 2 small molecule active

    1 trial
  5. anlotinib

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Sarcoma, Soft Tissue

    phase 2 small molecule active

    1 trial
  6. anlotinib +TQB2450 + Oxaliplatin+S-1

    The First People's Hospital of Lianyungang

    Advanced Gastric or Gastroesophageal Junction (G/GEJ) Adenocarcinoma

    phase 2 small molecule active

    1 trial
  7. anlotinib combined with penpulimab

    The First People's Hospital of Lianyungang

    Non-small Cell Lung Cancer

    phase 2 small molecule active

    1 trial
  8. anlotinib+TQB2450+nab-paclitaxel+cisplatin

    The First People's Hospital of Lianyungang

    Advanced Biliary Tract Cancer

    phase 2 small molecule active

    1 trial
  9. anti-BCMA CAR-T

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Plasma Cell Leukemia

    phase 2 mab active

    1 trial
  10. anti-BCMA-CAR-T

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Multiple Myeloma

    phase 2 mab active

    2 trials
  11. anti-BCMA/CD3 bispecific antibody

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Multiple Myeloma

    phase 2 small molecule active

    1 trial
  12. anti-CD133-CAR vector-transduced T cells

    Chinese PLA General Hospital

    Liver Cancer

    phase 2 mab completed

    1 trial
  13. anti-CD7 CAR-pNK cells

    The First People's Hospital of Lianyungang

    Acute Myeloid Leukemia

    phase 2 mab active

    1 trial
  14. anti-FLT3 CAR-T

    The First People's Hospital of Lianyungang

    Acute Myeloid Leukemia

    phase 2 mab active

    1 trial
  15. anti-MUC1 CAR-pNK cells

    The First People's Hospital of Lianyungang

    Hepatocellular Carcinoma

    phase 2 mab active

    1 trial
  16. anti-thymocyte globulin

    Ultragenyx UK Limited

    Fanconi's Anemia

    phase 2 small molecule completed

    1 trial
  17. anti-thymocyte globulin

    Ultragenyx UK Limited

    Systemic Sclerosis

    phase 2 small molecule completed

    1 trial
  18. arginine butyrate

    Ultragenyx UK Limited

    Beta-Thalassemia

    phase 2 small molecule completed

    1 trial
  19. armodafinil

    Teva Pharma GmbH

    Schizophrenia

    phase 2 small molecule completed

    2 trials
  20. artesunate

    Hospital Authority, Hong Kong

    Colorectal Cancer

    phase 2 small molecule active

    1 trial
  21. asparaginase Erwinia chrysanthemi

    Jazz Pharmaceuticals Ireland Limited

    Acute Lymphoblastic Leukemia

    phase 2 small molecule completed

    1 trial
  22. aspirin and atorvastatin

    United Therapeutics Europe Ltd

    Cardiovascular Risk Factor

    phase 2 small molecule active

    1 trial
  23. ataluren

    PTC THERAPEUTICS, INC.

    Epilepsy

    phase 2 small molecule completed

    1 trial
  24. atomoxetine

    BRIGHT MINDS BIOSCIENCES INC.

    Substance Abuse

    phase 2 small molecule completed

    1 trial
  25. atumelnant

    Crinetics Pharmaceuticals Europe GmbH

    Cushing Syndrome

    phase 2 small molecule active

    1 trial
  26. atumelnant (CRN04894)

    Crinetics Pharmaceuticals Europe GmbH

    Congenital Adrenal Hyperplasia

    phase 2 small molecule active

    2 trials
  27. auranofin

    Ultragenyx UK Limited

    Chronic Lymphocytic Leukemia (CLL)

    phase 2 small molecule completed

    1 trial
  28. autologous adipose-derived mesenchymal stem cell transplantation

    Hospital Authority, Hong Kong

    Aging Problems

    phase 2 mab active

    1 trial
  29. autologous anti-BCMA chimeric antigen receptor T cells

    The First People's Hospital of Lianyungang

    ITP

    phase 2 mab active

    1 trial
  30. autologous dendritic cells pulsed with tumor lysate antigen Vaccine

    NORTHWEST BIOTHERAPEUTICS INC

    Giant Cell Glioblastoma

    phase 2 mab terminated

    1 trial
  31. autologous mesenchymal stem cells implantation

    Teva Pharma GmbH

    Tibial Fracture

    phase 2 other completed

    1 trial
  32. autologous skin fibroblasts

    United Therapeutics Europe Ltd

    Wounds and Injuries

    phase 2 mab active

    1 trial
  33. avelumab

    Nektar Therapeutics UK Limited

    Squamous Cell Carcinoma of the Head and Neck (SCCHN)

    phase 2 small molecule terminated

    1 trial
  34. avelumab

    Samsung Bioepis NL B.V.

    Lymphoma, Extranodal NK-T-Cell

    phase 2 small molecule active

    1 trial
  35. avelumab (PD-L1 inhibitor immunotherapy) + lurbinectedin

    Jazz Pharmaceuticals Ireland Limited

    Metastatic Cancer

    phase 2 small molecule terminated

    1 trial
  36. azenosertib

    Zentalis Pharmaceuticals

    High-Grade Serous Ovarian, Fallopian Tube or Primary Peritoneal Cancer

    phase 2 small molecule active

    1 trial
  37. befotertinib

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    NSCLC (Non-small Cell Lung Cancer)

    phase 2 small molecule active

    1 trial
  38. bendamustine

    Teva Pharma GmbH

    Multiple Myeloma

    phase 2 small molecule completed

    1 trial
  39. bendamustine

    Teva Pharma GmbH

    Hodgkin Lymphoma

    phase 2 small molecule active

    2 trials
  40. bendamustine and rituximab

    Teva Pharma GmbH

    Non-Hodgkin's Lymphoma

    phase 2 small molecule completed

    1 trial
  41. benmelstobart

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    SCLC, Extensive Stage

    phase 2 small molecule active

    1 trial
  42. bevacizumab

    United Therapeutics Europe Ltd

    Colorectal Cancer

    phase 2 mab terminated

    1 trial
  43. bevacizumab [Avastin]

    Hoffmann-La Roche

    Liver Cancer

    phase 2 small molecule completed

    1 trial
  44. bexarotene

    LIGAND PHARMACEUTICALS INC

    Cutaneous T-Cell Lymphoma

    phase 2 small molecule completed

    1 trial
  45. bexarotene

    LIGAND PHARMACEUTICALS INC

    Breast Cancer

    phase 2 small molecule completed

    1 trial
  46. bezuclastinib

    Cogent Biosciences

    Advanced Systemic Mastocytosis (AdvSM)

    phase 2 small molecule active

    1 trial
  47. bilateral permanent occlusion of uterine arteries

    Universal Integrated

    Other Abnormal Uterine and Vaginal Bleeding

    phase 2 other completed

    1 trial
  48. bimekizumab

    Lacuna Pharma Pty Ltd

    Moderate to Severe Plaque Psoriasis

    phase 2 small molecule active

    1 trial

Frequently asked questions

How many Phase II pipeline programs are in the directory?

7,238 published programs match this development stage in our ClinicalTrials.gov index.

What defines this pipeline stage?

Phase and status reflect ClinicalTrials.gov registry fields at last sync. See our clinical trial phases reference for methodology.