Friday, July 10, 2026
🇺🇸 FDA

Intelligence · Clinical pipeline

Phase II Pipeline Programs

Proof-of-concept and dose-finding clinical programs in Phase II development.

Programs 7,238
Sponsors 1,771
Drugs 4,798

Quick answer

NovaPharmaNews tracks 7,238 phase ii pharmaceutical pipeline programs from ClinicalTrials.gov. Proof-of-concept and dose-finding clinical programs in Phase II development.

Top sponsors

Pipeline programs

Page 141 of 151

  1. Zonisamide

    United Therapeutics Europe Ltd

    Alcohol Dependence

    phase 2 small molecule completed

    1 trial

  2. Zonisamide 100Mg Cap

    United Therapeutics Europe Ltd

    Hearing Loss, Noise-Induced

    phase 2 small molecule terminated

    2 trials

  3. Zopiclone

    The First People's Hospital of Lianyungang

    Insomnia Chronic

    phase 2 small molecule completed

    1 trial

  4. Zr89

    Disc Medicine

    giant cell arteritis, rheumatoid arthritis

    phase 2 small molecule active

    1 trial

  5. Zuberitamab

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    HSCT

    phase 2 small molecule active

    1 trial

  6. Zumsemetinib

    Aclaris Therapeutics

    Hormone Receptor Positive HER-2 Negative Metastatic Breast Cancer

    phase 2 small molecule active

    1 trial

  7. Zydena (Udenafil)

    Samsung Bioepis NL B.V.

    Vascular Dementia

    phase 2 small molecule active

    1 trial

  8. [11C]CPPC PET ligand

    United Therapeutics Europe Ltd

    ALS

    phase 2 small molecule active

    1 trial

  9. [123I] 5-IA

    United Therapeutics Europe Ltd

    Parkinson Disease

    phase 2 small molecule completed

    1 trial

  10. [123I]B-CIT

    United Therapeutics Europe Ltd

    Parkinson Disease

    phase 2 small molecule completed

    1 trial

  11. [123I]β-CIT

    United Therapeutics Europe Ltd

    Parkinson Disease

    phase 2 small molecule active

    1 trial

  12. [177Lu]-NeoB solution for infusion, AAA503

    Advanced Accelerator Applications

    Solid tumors known to overexpress GRPR and with [68Ga]-NeoB lesion uptake.

    phase 2 small molecule active

    1 trial

  13. [18F]Fluor-PEG-Folate

    Disc Medicine

    giant cell arteritis

    phase 2 small molecule active

    1 trial

  14. [18F]PI-2620

    The George Institute

    Down Syndrome, Alzheimer disease

    phase 2 small molecule active

    1 trial

  15. [18F]PI-2620

    The George Institute

    Down Syndrome., Alzheimer´s Disease.

    phase 2 small molecule active

    1 trial

  16. [18F]PI-2620

    The George Institute

    Progressive supranuclear palsy, Parkinson's disease

    phase 2 small molecule active

    1 trial

  17. [18F]Tetrafluoroborate

    Disc Medicine

    Differentiated Thyroid Cancer

    phase 2 small molecule active

    1 trial

  18. [203Pb]Pb-PSV359

    Perspective Therapeutics

    Pancreatic Ductal Adenocarcinoma

    phase 2 small molecule active

    1 trial

  19. [203Pb]VMT-α-NET

    Perspective Therapeutics

    Neuroendocrine Tumors Unresectable

    phase 2 small molecule active

    1 trial

  20. [203Pb]VMT01

    Perspective Therapeutics

    Recurrent Melanoma (Skin)

    phase 2 small molecule active

    1 trial

  21. [6,6-2H2]glucose

    Ultragenyx UK Limited

    Glycogen Storage Disease Type IA

    phase 2 mab completed

    1 trial

  22. [68Ga]BED003 injection

    Blue Earth Diagnostics Ireland Ltd

    Colorectal cancer (CRC), gastric cancer (GC), pancreatic ductal adenocarcinoma (PDAC), invasive lobular breast cancer (ILC), and epithelial ovarian cancer (EOC).

    phase 2 small molecule active

    1 trial

  23. [68Ga]FAPI-46

    Disc Medicine

    giant cell arteritis - polymyalgia rheumatica spectrum disease

    phase 2 small molecule active

    1 trial

  24. [68Ga]Ga-PentixaFor

    Disc Medicine

    Cardiac Sarcoidosis

    phase 2 small molecule active

    1 trial

  25. a standardized physical therapy program

    Hospital Authority, Hong Kong

    Frozen Shoulder

    phase 2 other completed

    1 trial

  26. abituzumab

    United Therapeutics Europe Ltd

    Metastatic Colorectal Cancer

    phase 2 small molecule terminated

    1 trial

  27. accelerated intermittent theta burst stimulation

    United Therapeutics Europe Ltd

    Long COVID

    phase 2 other active

    1 trial

  28. acetylsalicylic acid

    Protalix BioTherapeutics

    Upper Gastrointestinal Mucosal Damage

    phase 2 small molecule completed

    1 trial

  29. activated recombinant human factor VII

    Novo Nordisk A/S

    Acquired Bleeding Disorder

    phase 2 small molecule completed

    2 trials

  30. acupuncture

    Hospital Authority, Hong Kong

    Peripheral Neuropathy Grade 2 or Greater

    phase 2 other terminated

    1 trial

  31. aerobic exercise

    BRIGHT MINDS BIOSCIENCES INC.

    Nicotine Dependence

    phase 2 other completed

    1 trial

  32. aerosolized vancomycin or gentamicin

    Nektar Therapeutics UK Limited

    Ventilator Associated Pneumonia

    phase 2 small molecule completed

    1 trial

  33. affect regulation training

    BRIGHT MINDS BIOSCIENCES INC.

    Smoking Cessation

    phase 2 other completed

    1 trial

  34. aflibercept

    Regeneron UK Limited

    Neovascular (Wet) Age-Related Macular Degeneration

    phase 2 small molecule completed

    1 trial

  35. aflibercept + FOLFIRI

    Regeneron UK Limited

    Metastatic Colorectal Cancer

    phase 2 small molecule terminated

    1 trial

  36. aglatimagene besadenovec

    Candel Therapeutics

    Prostate Cancer

    phase 2 mab active

    1 trial

  37. aglatimagene besadenovec + valacyclovir

    Candel Therapeutics

    Prostate Cancer Patients Treated by Radiotherapy

    phase 2 mab active

    1 trial

  38. alb-interferon alfa 2b

    Novartis Pharmaceuticals

    Chronic Hepatitis C

    phase 2 small molecule completed

    1 trial

  39. albiglutide

    GlaxoSmithKline

    Diabetes Mellitus, Type 2

    phase 2 mab completed

    1 trial

  40. albuterol inhalation powder

    Amphastar France Pharmaceuticals

    Asthma

    phase 2 small molecule completed

    1 trial

  41. aleniglipron or placebo

    Structure Therapeutics

    Obesity

    phase 2 small molecule completed

    1 trial

  42. alisertib

    Takeda

    Malignant Rhabdoid Tumor

    phase 2 small molecule active

    1 trial

  43. allogeneic human mesenchymal stem cells (hMSCs)

    United Therapeutics Europe Ltd

    Non-ischemic Dilated Cardiomyopathy

    phase 2 mab active

    1 trial

  44. allopurinol

    Ultragenyx UK Limited

    Leishmaniasis

    phase 2 small molecule completed

    1 trial

  45. alpha 1H, Placebo product for Alpha1H

    Lacuna Pharma Pty Ltd

    Non-muscle invasive bladder cancer awaiting transurethral surgery

    phase 2 small molecule active

    1 trial

  46. alprazolam

    BRIGHT MINDS BIOSCIENCES INC.

    Anxiety Disorder

    phase 2 small molecule completed

    1 trial

  47. alvimopan

    Merck KGaA, Darmstadt, Germany

    Constipation

    phase 2 small molecule completed

    1 trial

  48. aminomidazole carboxamide riboside

    Ultragenyx UK Limited

    Lesch-Nyhan Syndrome

    phase 2 small molecule completed

    1 trial

Frequently asked questions

How many Phase II pipeline programs are in the directory?

7,238 published programs match this development stage in our ClinicalTrials.gov index.

What defines this pipeline stage?

Phase and status reflect ClinicalTrials.gov registry fields at last sync. See our clinical trial phases reference for methodology.

Drug approvals, clinical trials, M&A, event intelligence, and company updates — weekly.

Customize topics & region
Topics
Region

No spam. Unsubscribe anytime. See our privacy policy.