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Intelligence · Clinical pipeline

Phase II Pipeline Programs

Proof-of-concept and dose-finding clinical programs in Phase II development.

Programs 7,238
Sponsors 1,771
Drugs 4,798

Quick answer

NovaPharmaNews tracks 7,238 phase ii pharmaceutical pipeline programs from ClinicalTrials.gov. Proof-of-concept and dose-finding clinical programs in Phase II development.

Top sponsors

Pipeline programs

Page 136 of 151

  1. VX-371 + HS

    Vertex Pharmaceuticals (Australia) Pty.

    Cystic Fibrosis

    phase 2 small molecule completed

    1 trial

  2. VX-407

    Vertex Pharmaceuticals (Australia) Pty.

    Autosomal Dominant Polycystic Kidney Disease (ADPKD)

    phase 2 small molecule active

    4 trials

  3. VX-407 tablet

    Vertex Pharmaceuticals (Australia) Pty.

    Autosomal Dominant Polycystic Kidney Disease (ADPKD)

    phase 2 small molecule active

    1 trial

  4. VX-522 mRNA therapy

    Vertex Pharmaceuticals (Australia) Pty.

    Cystic Fibrosis

    phase 2 small molecule active

    1 trial

  5. VX-548

    Vertex Pharmaceuticals (Australia) Pty.

    Painful Lumbosacral Radiculopathy

    phase 2 small molecule completed

    1 trial

  6. VX-548

    Vertex Pharmaceuticals (Australia) Pty.

    Acute Pain

    phase 2 small molecule completed

    2 trials

  7. VX-561

    Vertex Pharmaceuticals (Australia) Pty.

    Cystic Fibrosis

    phase 2 small molecule terminated

    2 trials

  8. VX-659

    Vertex Pharmaceuticals (Australia) Pty.

    Cystic Fibrosis

    phase 2 small molecule completed

    2 trials

  9. VX-661

    Vertex Pharmaceuticals (Australia) Pty.

    Cystic Fibrosis

    phase 2 small molecule completed

    2 trials

  10. VX-670

    Vertex Pharmaceuticals (Australia) Pty.

    Myotonic Dystrophy Type 1 (DM1)

    phase 2 small molecule active

    2 trials

  11. VX-670 Solution for Injection/Infusion

    Vertex Pharmaceuticals (Australia) Pty.

    Myotonic Dystrophy

    phase 2 small molecule active

    1 trial

  12. VX-702

    Vertex Pharmaceuticals (Australia) Pty.

    Rheumatoid Arthritis

    phase 2 small molecule completed

    2 trials

  13. VX-765

    Vertex Pharmaceuticals (Australia) Pty.

    Psoriasis

    phase 2 small molecule completed

    1 trial

  14. VX-765

    Vertex Pharmaceuticals (Australia) Pty.

    Partial Epilepsy

    phase 2 small molecule completed

    1 trial

  15. VX-765 Part A

    Vertex Pharmaceuticals (Australia) Pty.

    Epilepsy

    phase 2 small molecule terminated

    1 trial

  16. VX-770

    Vertex Pharmaceuticals (Australia) Pty.

    Cystic Fibrosis

    phase 2 small molecule completed

    3 trials

  17. VX-787

    Vertex Pharmaceuticals (Australia) Pty.

    Influenza Virus

    phase 2 small molecule completed

    1 trial

  18. VX-814

    Vertex Pharmaceuticals (Australia) Pty.

    Alpha 1-Antitrypsin Deficiency

    phase 2 small molecule terminated

    1 trial

  19. VX-864

    Vertex Pharmaceuticals (Australia) Pty.

    Alpha-1 Antitrypsin Deficiency

    phase 2 small molecule terminated

    1 trial

  20. VX-864

    Vertex Pharmaceuticals (Australia) Pty.

    Alpha1-Antitrypsin Deficiency

    phase 2 small molecule completed

    1 trial

  21. VX-950

    Vertex Pharmaceuticals (Australia) Pty.

    Hepatitis C

    phase 2 small molecule completed

    2 trials

  22. VX-993

    Vertex Pharmaceuticals (Australia) Pty.

    Acute Pain

    phase 2 small molecule completed

    1 trial

  23. VX-993

    Vertex Pharmaceuticals (Australia) Pty.

    Diabetic Peripheral Neuropathic Pain

    phase 2 small molecule active

    1 trial

  24. VX15/2503

    VACCINEX, INC.

    Huntington's Disease

    phase 2 small molecule completed

    1 trial

  25. VX15/2503 + avelumab

    VACCINEX, INC.

    Carcinoma, Non-Small-Cell Lung

    phase 2 small molecule completed

    1 trial

  26. VX23-670-001

    Vertex Pharmaceuticals (Australia) Pty.

    Myotonic Dystrophy

    phase 2 small molecule active

    1 trial

  27. VX24-993-103

    Vertex Pharmaceuticals (Australia) Pty.

    Pain Associated With Diabetic Peripheral Neuropathy

    phase 2 small molecule active

    1 trial

  28. VY7523

    Voyager Therapeutics

    Alzheimer's Disease (AD)

    phase 2 small molecule active

    1 trial

  29. VYN201 Gel

    VYNE Therapeutics

    Non-segmental Vitiligo

    phase 2 small molecule terminated

    1 trial

  30. Vaborem 1 g/1 g powder for concentrate for solution for infusion

    A.Menarini Australia Pty Limited

    Suspected or confirmed Gram negative infections

    phase 2 small molecule active

    1 trial

  31. Vaccine

    Atrium Therapeutics

    Pediatric Cancer

    phase 2 mab active

    1 trial

  32. Vaccine PvCS N+C+R

    BRIGHT MINDS BIOSCIENCES INC.

    Malaria

    phase 2 mab completed

    1 trial

  33. Vaccine PvCS N+C+R 150 mcg

    BRIGHT MINDS BIOSCIENCES INC.

    Malaria, Vivax

    phase 2 mab active

    1 trial

  34. Vadadustat

    Akebia Europe Limited

    Chronic Kidney Disease

    phase 2 small molecule completed

    1 trial

  35. Valaciclovir/Aciclovir

    United Therapeutics Europe Ltd

    Critical Illness

    phase 2 small molecule completed

    1 trial

  36. Valbenazine

    NEUROCRINE BIOSCIENCES INC

    Tourette Syndrome

    phase 2 small molecule completed

    4 trials

  37. Valbenazine

    NEUROCRINE BIOSCIENCES INC

    Obsessive-Compulsive Disorder

    phase 2 small molecule active

    1 trial

  38. Valbenazine Oral Capsule

    NEUROCRINE BIOSCIENCES INC

    Trichotillomania (Hair-Pulling Disorder)

    phase 2 small molecule active

    1 trial

  39. Valemetostat Tosylate, Valemetostat Tosylate

    The George Institute

    Adult patients with histologically/cytologically confirmed progressive metastatic or recurrent solid tumor, who have selected chromatin remodeling deficiency in at least one of the following genes: SMARCB1, SMARCA4, SMARCA2, SMARCC1, SMARCC2, ARID1A, ARID1B, PBRM1, BAP1and other SWI/SNF sub-units; or molecularly (Wildtype) and phenotypically-selected Clear cell endometrial or ovarian carcinoma cancers.

    phase 2 small molecule active

    1 trial

  40. Valemetostat Tosylate, Valemetostat Tosylate

    Daiichi Sankyo

    Relapsed/Refractory Peripheral T-Cell Lymphoma

    phase 2 small molecule active

    1 trial

  41. Valoctocogene roxaparvovec

    BioMarin Pharmaceutical Australia Pty Ltd

    Hemophilia A With Inhibitor

    phase 2 mab active

    1 trial

  42. Valproate

    BRIGHT MINDS BIOSCIENCES INC.

    Bipolar Disorder

    phase 2 small molecule completed

    1 trial

  43. Valproic Acid

    United Therapeutics Europe Ltd

    Retinitis Pigmentosa

    phase 2 small molecule completed

    1 trial

  44. Valproic Acid

    United Therapeutics Europe Ltd

    Pain, Phantom

    phase 2 small molecule completed

    1 trial

  45. Valproic Acid Solution

    United Therapeutics Europe Ltd

    Acute Kidney Injury

    phase 2 small molecule terminated

    1 trial

  46. Vancomycin

    Cardiff Oncology

    Late Onset Neonatal Sepsis

    phase 2 small molecule terminated

    1 trial

  47. Vancomycin Pre-Treatment

    Seres Therapeutics

    Ulcerative Colitis

    phase 2 small molecule terminated

    1 trial

  48. Vancomycin and bowel lavage

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Slow Transit Constipation

    phase 2 small molecule active

    1 trial

Frequently asked questions

How many Phase II pipeline programs are in the directory?

7,238 published programs match this development stage in our ClinicalTrials.gov index.

What defines this pipeline stage?

Phase and status reflect ClinicalTrials.gov registry fields at last sync. See our clinical trial phases reference for methodology.

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