Friday, July 10, 2026
🇺🇸 FDA

Intelligence · Clinical pipeline

Phase II Pipeline Programs

Proof-of-concept and dose-finding clinical programs in Phase II development.

Programs 7,238
Sponsors 1,771
Drugs 4,798

Quick answer

NovaPharmaNews tracks 7,238 phase ii pharmaceutical pipeline programs from ClinicalTrials.gov. Proof-of-concept and dose-finding clinical programs in Phase II development.

Top sponsors

Pipeline programs

Page 134 of 151

  1. Upadacitinib

    AbbVie

    Non-Segmental Vitiligo

    phase 2 small molecule completed

    1 trial

  2. Upadacitinib

    AbbVie

    Hidradenitis Suppurativa (HS)

    phase 2 small molecule completed

    1 trial

  3. Upadacitinib, Upadacitinib

    AbbVie Deutschland GmbH & Co. KG

    Crohn's Disease (CD)

    phase 2 small molecule active

    1 trial

  4. Upamostat

    RedHill Biopharma

    SARS-CoV-2

    phase 2 small molecule completed

    1 trial

  5. Uplizna 100 mg concentrate for solution for infusion

    Amgen

    Generalized Myasthenia Gravis

    phase 2 small molecule active

    1 trial

  6. Uplizna 100 mg concentrate for solution for infusion

    Amgen

    Immunoglobulin G4 related Disease (IgG4-RD)

    phase 2 small molecule active

    1 trial

  7. Ursodeoxycholic acid

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    COVID-19

    phase 2 small molecule completed

    1 trial

  8. Ursodeoxycholic acid

    Hospital Authority, Hong Kong

    Hepatitis D

    phase 2 small molecule active

    1 trial

  9. Utidelone

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Breast Cancer

    phase 2 small molecule active

    1 trial

  10. V940-004

    Merck Sharp and Dohme

    Intermediate-high -risk RCC, high-risk RCC who have undergone nephrectomy, or M1 NED RCC who have undergone nephrectomy and metastasectomy.

    phase 2 small molecule active

    1 trial

  11. V940-005

    Merck Sharp and Dohme

    Muscle-invasive Urothelial Carcinoma

    phase 2 small molecule active

    1 trial

  12. V940-012

    Merck Sharp and Dohme

    Melanoma

    phase 2 small molecule active

    1 trial

  13. V940-013

    Merck Sharp and Dohme

    Non-small cell lung cancer stage IV

    phase 2 small molecule active

    1 trial

  14. VAC059

    United Therapeutics Europe Ltd

    Plasmodium Falciparum Malaria

    phase 2 mab completed

    1 trial

  15. VACl

    The First People's Hospital of Lianyungang

    Acute Myeloid Leukemia, Adult

    phase 2 small molecule active

    1 trial

  16. VAN00013

    Sanofi-aventis Healthcare Pty Ltd

    Meningococcal immunization

    phase 2 small molecule active

    1 trial

  17. VANCOMYCIN , MaaT013

    Lacuna Pharma Pty Ltd

    Gastrointestinal Acute Graft-versus-Host Disease (GI-aGvHD)

    phase 2 small molecule active

    1 trial

  18. VATS

    The First People's Hospital of Lianyungang

    Non-small Cell Lung Cancer

    phase 2 other active

    1 trial

  19. VB10.NEO

    Nektar Therapeutics UK Limited

    Locally Advanced or Metastatic Solid Tumours

    phase 2 mab completed

    1 trial

  20. VBR

    ASSEMBLY BIOSCIENCES, INC.

    Chronic Hepatitis B

    phase 2 small molecule terminated

    1 trial

  21. VC-02 Combination Product

    Vertex Pharmaceuticals (Australia) Pty.

    Type 1 Diabetes Mellitus With Hypoglycemia

    phase 2 other completed

    1 trial

  22. VCA-894A

    Vanda Pharmaceuticals Netherlands B.V.

    Charcot Marie Tooth Disease (CMT)

    phase 2 small molecule active

    1 trial

  23. VCAR33

    Vor Biopharma

    Leukemia, Myeloid, Acute

    phase 2 mab terminated

    1 trial

  24. VCH-222 or matching placebo

    Vertex Pharmaceuticals (Australia) Pty.

    Hepatitis C

    phase 2 small molecule completed

    1 trial

  25. VCH-759 (BCH-27759)

    Vertex Pharmaceuticals (Australia) Pty.

    Hepatitis C, Chronic

    phase 2 small molecule completed

    1 trial

  26. VDA-1102, VDA-1102 placebo

    Lacuna Pharma Pty Ltd

    Actinic keratosis

    phase 2 small molecule active

    1 trial

  27. VEC-162

    Vanda Pharmaceuticals Netherlands B.V.

    Circadian Rhythm Sleep Disorders

    phase 2 small molecule completed

    1 trial

  28. VEGF Trap Eye

    Regeneron UK Limited

    Macular Degeneration

    phase 2 small molecule completed

    1 trial

  29. VEGF inhibitor PTC299

    PTC THERAPEUTICS, INC.

    Kaposi's Sarcoma

    phase 2 small molecule terminated

    1 trial

  30. VEN (Venetoclax)

    The First People's Hospital of Lianyungang

    Myelodysplastic Neoplasms

    phase 2 small molecule active

    1 trial

  31. VEN (Venetoclax)

    The First People's Hospital of Lianyungang

    Adult T-cell Leukemia/Lymphoma

    phase 2 small molecule active

    1 trial

  32. VEN+AZA+Modified BUCY

    The First People's Hospital of Lianyungang

    Allogeneic Hematopoietic Stem Cell Transplantation

    phase 2 small molecule active

    2 trials

  33. VESANOID 10 mg, capsule molle

    The George Institute

    Oligometastatic solid cancer

    phase 2 small molecule active

    1 trial

  34. VESLETEPLIRSEN(SRP-5051)

    Sarepta Therapeutics

    Duchenne Muscular Dystrophy

    phase 2 small molecule active

    1 trial

  35. VESPA

    Fondazione Telethon ETS

    Metastatic pancreatic ductal adenocarcinoma (mPDAC)

    phase 2 small molecule active

    1 trial

  36. VGFT-OD-0508

    Regeneron UK Limited

    Macular Degeneration

    phase 2 mab completed

    1 trial

  37. VGX 3100

    INOVIO PHARMACEUTICALS, INC.

    Cervical Intraepithelial Neoplasia

    phase 2 mab completed

    1 trial

  38. VGX-3100

    INOVIO PHARMACEUTICALS, INC.

    Vulvar High Grade Squamous Intraepithelial Lesion (HSIL)

    phase 2 mab completed

    1 trial

  39. VGX-3100

    INOVIO PHARMACEUTICALS, INC.

    Anal Neoplasm

    phase 2 mab completed

    1 trial

  40. VHIO17002

    The George Institute

    Subjects with advanced solid tumour

    phase 2 small molecule active

    1 trial

  41. VHIO19001

    The George Institute

    Resectable Gastric cancer (GC) or Gastroesophageal Junction cancer (GEJC)

    phase 2 small molecule active

    1 trial

  42. VHIO23001

    The George Institute

    Metastatic colorectal cancer

    phase 2 small molecule active

    1 trial

  43. VHIO23002

    The George Institute

    Advanced selected solid tumors: melanoma, non-small cell lung cancer (NSCLC) and cervical cancer.

    phase 2 small molecule active

    1 trial

  44. VHIO24002

    The George Institute

    Patients with localized renal cell carcinoma

    phase 2 small molecule active

    1 trial

  45. VINORELBINE for Hodgkin’s lymphoma

    Fondazione Telethon ETS

    Hodgkin’s lymphoma

    phase 2 small molecule active

    1 trial

  46. VIR-2218

    Vir Biotechnology

    Hepatitis D, Chronic

    phase 2 small molecule active

    1 trial

  47. VIR-2218

    Vir Biotechnology

    Chronic Hepatitis B

    phase 2 small molecule completed

    1 trial

  48. VIR-2218

    Alnylam Netherlands B.V.

    Chronic Hepatitis B

    phase 2 small molecule completed

    2 trials

Frequently asked questions

How many Phase II pipeline programs are in the directory?

7,238 published programs match this development stage in our ClinicalTrials.gov index.

What defines this pipeline stage?

Phase and status reflect ClinicalTrials.gov registry fields at last sync. See our clinical trial phases reference for methodology.

Drug approvals, clinical trials, M&A, event intelligence, and company updates — weekly.

Customize topics & region
Topics
Region

No spam. Unsubscribe anytime. See our privacy policy.