Saturday, July 11, 2026

Intelligence · Clinical pipeline

Phase II Pipeline Programs

Proof-of-concept and dose-finding clinical programs in Phase II development.

Programs 7,238
Sponsors 1,771
Drugs 4,798

Quick answer

NovaPharmaNews tracks 7,238 phase ii pharmaceutical pipeline programs from ClinicalTrials.gov. Proof-of-concept and dose-finding clinical programs in Phase II development.

Top sponsors

Pipeline programs

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  1. Toripalimab

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Triple-Negative Breast Cancer (TNBC)

    phase 2 small molecule active

    1 trial
  2. Toripalimab

    The First People's Hospital of Lianyungang

    Pancreatic Carcinoma

    phase 2 small molecule active

    1 trial
  3. Toripalimab

    Coherus Oncology

    Head and Neck Squamous Cell Carcinoma (HNSCC) - Recurrent/Metastatic (R/M)

    phase 2 small molecule active

    1 trial
  4. Toripalimab

    Coherus Oncology

    Localized Colon Carcinoma

    phase 2 small molecule active

    1 trial
  5. Toripalimab

    The First People's Hospital of Lianyungang

    Adenocarcinoma of the Stomach

    phase 2 small molecule active

    1 trial
  6. Toripalimab

    Coherus Oncology

    Sinonasal Cancer

    phase 2 small molecule active

    1 trial
  7. Toripalimab

    The First People's Hospital of Lianyungang

    Small Cell Lung Cancer Limited Stage

    phase 2 small molecule terminated

    1 trial
  8. Toripalimab

    The First People's Hospital of Lianyungang

    Upper Tract Urothelial Carcinoma

    phase 2 small molecule active

    1 trial
  9. Toripalimab

    The First People's Hospital of Lianyungang

    Urinary Bladder Neoplasms

    phase 2 small molecule active

    1 trial
  10. Toripalimab

    Yongchang Zhang

    Advanced Non Small Cell Lung Cancer

    phase 2 small molecule completed

    1 trial
  11. Toripalimab

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Tracheal Squamous Cell Carcinoma

    phase 2 small molecule active

    1 trial
  12. Toripalimab

    The First People's Hospital of Lianyungang

    Breast Cancer

    phase 2 small molecule active

    1 trial
  13. Toripalimab + Chemotherapy

    Coherus Oncology

    Head and Neck Cancer

    phase 2 small molecule active

    1 trial
  14. Toripalimab + Chemotherapy

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Thymic Epithelial Tumor

    phase 2 small molecule active

    1 trial
  15. Toripalimab+Nedaplatin+Albumin Paclitaxel

    The First People's Hospital of Lianyungang

    Locally Advanced Esophageal Squamous Cell Carcinoma

    phase 2 small molecule active

    1 trial
  16. Toripalimab-tpzi

    Coherus Oncology

    Squamous Cell Carcinoma

    phase 2 small molecule active

    1 trial
  17. Total Neoadjuvant Treatment

    The First People's Hospital of Lianyungang

    Biliary Tract Neoplasms

    phase 2 small molecule active

    1 trial
  18. Tovorafenib, Tovorafenib

    Lacuna Pharma Pty Ltd

    RAF-Altered, Recurrent or Progressive Low-Grade Glioma and Advanced Solid Tumors in pediatric patients

    phase 2 small molecule active

    1 trial
  19. Tovorafenib, Tovorafenib

    AXIM BIOTECHNOLOGIES, INC.

    craniopharyngioma

    phase 2 small molecule active

    1 trial
  20. Tozorakimab

    AstraZeneca

    Asthma

    phase 2 small molecule active

    1 trial
  21. Tradipitant

    Vanda Pharmaceuticals Netherlands B.V.

    Obesity

    phase 2 small molecule completed

    1 trial
  22. Tradipitant

    Vanda Pharmaceuticals Netherlands B.V.

    Healthy Volunteer

    phase 2 small molecule completed

    1 trial
  23. Traditional Chinese acupuncture

    The University of Hong Kong

    Phonotraumatic Injuries

    phase 2 other active

    1 trial
  24. Traditional fabricated prosthetic socket

    United Therapeutics Europe Ltd

    Amputation

    phase 2 other completed

    1 trial
  25. Tralokinumab 300 mg, Q2W

    MedImmune

    Asthma

    phase 2 mab completed

    1 trial
  26. Tramadol

    BRIGHT MINDS BIOSCIENCES INC.

    Opioid-Related Disorders

    phase 2 small molecule completed

    2 trials
  27. Trametinib (GSK1120212)

    ADIAL PHARMACEUTICALS, INC.

    Melanoma

    phase 2 small molecule completed

    1 trial
  28. Tranexamic Acid

    United Therapeutics Europe Ltd

    Anterior Cruciate Ligament Reconstruction

    phase 2 small molecule active

    1 trial
  29. Tranexamic Acid

    Neuroscience Trials Australia

    Intracerebral Haemorrhage

    phase 2 small molecule completed

    1 trial
  30. Tranexamic Acid

    United Therapeutics Europe Ltd

    Hemorrhage

    phase 2 small molecule completed

    1 trial
  31. TransCon CNP, Placebo for TransCon CNP

    Lacuna Pharma Pty Ltd

    Achondroplasia in Children and Adolescents

    phase 2 small molecule active

    1 trial
  32. TransCon PTH

    Ascendis Pharma Bone Diseases A/S

    Hypoparathyroidism (HP) in Adults

    phase 2 small molecule active

    1 trial
  33. Transarterial chemoembolization

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Unresectable Colorectal Cancer

    phase 2 other active

    1 trial
  34. Transdermal Nicotine Patch

    BRIGHT MINDS BIOSCIENCES INC.

    Cigarette Smoking

    phase 2 small molecule completed

    1 trial
  35. Transdermal Nicotine patch

    BRIGHT MINDS BIOSCIENCES INC.

    Tobacco Smoking

    phase 2 small molecule completed

    1 trial
  36. Transplantation of Autologous stem cell [MNCs] .

    Hospital Authority, Hong Kong

    Spinal Cord Injury.

    phase 2 mab active

    1 trial
  37. Trastuzumab

    PUMA BIOTECHNOLOGY, INC.

    Metastatic Colorectal Cancer

    phase 2 small molecule active

    1 trial
  38. Trastuzumab

    United Therapeutics Europe Ltd

    Metastatic Colon Adenocarcinoma

    phase 2 mab terminated

    1 trial
  39. Trastuzumab

    United Therapeutics Europe Ltd

    Metastatic Colorectal Adenocarcinoma

    phase 2 small molecule completed

    1 trial
  40. Trastuzumab

    KAZIA THERAPEUTICS LTD

    Breast Cancer

    phase 2 small molecule terminated

    1 trial
  41. Trastuzumab deruxtecan

    AstraZeneca

    Advanced Solid Tumors With HER2 Mutation,eg:Colorectal,Urothelial,Gastric, Hepatobiliary,Endometrial,Melanoma,Ovarian,Cervical,Salivary Gland,Pancreatic,Breast

    phase 2 small molecule active

    1 trial
  42. Trastuzumab in Combination with TS-ONE and cisplatin

    Hospital Authority, Hong Kong

    Gastric Cancer

    phase 2 small molecule active

    1 trial
  43. Treatment as Usual

    Camp4 Therapeutics Corp

    Post-Traumatic Stress Disorder

    phase 2 other completed

    1 trial
  44. Treprostinil

    United Therapeutics Europe Ltd

    Ischemia Reperfusion Injury

    phase 2 small molecule active

    1 trial
  45. Treprostinil Inhalation Solution

    United Therapeutics Europe Ltd

    Respiratory Distress Syndrome, Adult

    phase 2 small molecule terminated

    1 trial
  46. Trevogrumab-Part A

    Regeneron UK Limited

    Obesity

    phase 2 small molecule active

    1 trial
  47. Triamcinolone Acetonide Acetate and Urea Cream.

    Universal Integrated

    Psoriasis Vulgaris

    phase 2 small molecule active

    1 trial
  48. Trichostatin A

    Vanda Pharmaceuticals Netherlands B.V.

    Onychomycosis of Toenail

    phase 2 small molecule active

    1 trial

Frequently asked questions

How many Phase II pipeline programs are in the directory?

7,238 published programs match this development stage in our ClinicalTrials.gov index.

What defines this pipeline stage?

Phase and status reflect ClinicalTrials.gov registry fields at last sync. See our clinical trial phases reference for methodology.