Saturday, July 11, 2026

Intelligence · Clinical pipeline

Phase II Pipeline Programs

Proof-of-concept and dose-finding clinical programs in Phase II development.

Programs 7,238
Sponsors 1,771
Drugs 4,798

Quick answer

NovaPharmaNews tracks 7,238 phase ii pharmaceutical pipeline programs from ClinicalTrials.gov. Proof-of-concept and dose-finding clinical programs in Phase II development.

Top sponsors

Pipeline programs

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  1. Temozolomide

    The First People's Hospital of Lianyungang

    Cytokine-Induced Killer Cells

    phase 2 small molecule active

    1 trial
  2. Temsirolimus

    PUMA BIOTECHNOLOGY, INC.

    Breast Cancer

    phase 2 small molecule completed

    1 trial
  3. Tenecteplase

    Neuroscience Trials Australia

    Ischemic Stroke

    phase 2 small molecule completed

    1 trial
  4. Teniposide administration

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Extensive-stage Small Cell Lung Cancer (ES-SCLC)

    phase 2 small molecule active

    1 trial
  5. Tenofovir Alafenamide

    Vir Biotechnology

    Chronic Hepatitis B

    phase 2 small molecule completed

    1 trial
  6. Tenofovir gel

    United Therapeutics Europe Ltd

    HIV Infections

    phase 2 small molecule completed

    1 trial
  7. Tenofovir/lamivudine/lopinavir-ritonavir

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    HIV

    phase 2 small molecule completed

    1 trial
  8. Tepotinib

    Serono Europe Limited

    Advanced (Stage IIIB/IV) Non-small Cell Lung Cancer (NSCLC) With MET Exon 14 (METex14) Skipping Alterations or MET Amplification

    phase 2 small molecule active

    1 trial
  9. Tepotinib

    Merck Sharp and Dohme

    Lung Cancer

    phase 2 small molecule active

    1 trial
  10. Terbinafin "Moberg Pharma" for Distal Subungual Onychomycosis

    Lacuna Pharma Pty Ltd

    Distal Subungual Onychomycosis

    phase 2 small molecule active

    1 trial
  11. Teriflunomide

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Immune Thrombocytopenia

    phase 2 small molecule active

    2 trials
  12. Teriparatide

    United Therapeutics Europe Ltd

    Spinal Cord Injury

    phase 2 small molecule completed

    1 trial
  13. Tesamorelin 2 Milligrams (MG)

    United Therapeutics Europe Ltd

    Peripheral Nerve Injuries

    phase 2 small molecule active

    1 trial
  14. Test Drug

    BRIGHT MINDS BIOSCIENCES INC.

    Heroin Dependence

    phase 2 small molecule terminated

    1 trial
  15. Testosterone Enanthate 100 MG/ML Injectable Solution

    Hospital Authority, Hong Kong

    Castration-resistant Prostate Cancer

    phase 2 small molecule active

    1 trial
  16. Testosterone Gel applied by a pump

    United Therapeutics Europe Ltd

    Spinal Cord Injury

    phase 2 small molecule active

    1 trial
  17. Testosterone cypionate

    United Therapeutics Europe Ltd

    Castration Resistant Metastatic Prostate Cancer

    phase 2 small molecule completed

    1 trial
  18. Tetrahydrobiopterin

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Radiation Enteritis

    phase 2 small molecule active

    1 trial
  19. Teverelix TFA

    Nordic Bioscience A/S

    Advanced prostate cancer

    phase 2 small molecule active

    1 trial
  20. Tevimbra 100 mg concentrate for solution for infusion

    Ningbo Cancer Hospital

    Patients with Hepatocellular Carcinoma (HCC) and Child-Pugh B, ALBI grade 1 or 2 liver function, pretreated or not by tyrosine kinase inhibitors and not pretreated with immunotherapy.

    phase 2 small molecule active

    1 trial
  21. Tezacaftor/Ivacaftor + Ivacaftor

    Vertex Pharmaceuticals (Australia) Pty.

    Cystic Fibrosis

    phase 2 small molecule completed

    1 trial
  22. Thalidomide and methotrexate

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    T-LGL Leukemia

    phase 2 small molecule active

    1 trial
  23. The BiRCh Study

    Insmed Limited

    Chronic Rhinosinusitis without Nasal Polyps (CRSsNP)

    phase 2 small molecule active

    1 trial
  24. The Modular Protocol for Mental Health

    COGNITION THERAPEUTICS INC

    Major Depressive Disorder

    phase 2 other completed

    1 trial
  25. The Placebo composition is the same of the IMP except the active ingredient

    Fondazione Telethon ETS

    Optic Pathway Glioma (OPG)

    phase 2 small molecule active

    1 trial
  26. Theory-based counseling program

    BRIGHT MINDS BIOSCIENCES INC.

    HIV Infections

    phase 2 other completed

    1 trial
  27. Thiotepa

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Hematologic Malignancies

    phase 2 small molecule active

    1 trial
  28. Thyroplasty

    United Therapeutics Europe Ltd

    Vocal Cord Paralysis Unilateral

    phase 2 other completed

    1 trial
  29. Tiagabine

    BRIGHT MINDS BIOSCIENCES INC.

    Cocaine-Related Disorders

    phase 2 small molecule completed

    1 trial
  30. Tibolone

    United Therapeutics Europe Ltd

    Menopause

    phase 2 small molecule completed

    1 trial
  31. Tideglusib

    Rhythm Pharmaceuticals Netherlands B.V.

    Arrhythmogenic Cardiomyopathy

    phase 2 small molecule active

    1 trial
  32. TigetT10_MPSIH

    Orchard Therapeutics (Netherlands) B.V.

    Mucopolysaccharidosis type I Hurler

    phase 2 small molecule active

    1 trial
  33. Tildacerfont

    SPRUCE BIOSCIENCES, INC.

    Congenital Adrenal Hyperplasia

    phase 2 small molecule terminated

    1 trial
  34. Tildacerfont

    SPRUCE BIOSCIENCES, INC.

    Polycystic Ovary Syndrome

    phase 2 small molecule terminated

    1 trial
  35. Tildacerfont/Placebo

    SPRUCE BIOSCIENCES, INC.

    Congenital Adrenal Hyperplasia

    phase 2 small molecule terminated

    2 trials
  36. Tiotropium HFA BAI 4.5 mcg

    Teva Pharma GmbH

    COPD

    phase 2 small molecule completed

    1 trial
  37. Tiotropium HFA BAI 5 mcg

    Teva Pharma GmbH

    Chronic Obstructive Pulmonary Disease

    phase 2 small molecule terminated

    1 trial
  38. Tipifarnib

    Kura Oncology

    Relapsed or Refractory Peripheral T-Cell Lymphoma

    phase 2 small molecule completed

    1 trial
  39. Tipifarnib

    Kura Oncology

    HNSCC

    phase 2 small molecule completed

    1 trial
  40. Tipifarnib

    Kura Oncology

    HRAS Gene Mutation

    phase 2 small molecule completed

    1 trial
  41. Tipifarnib

    Kura Oncology

    Leukemia, Myelomonocytic, Chronic

    phase 2 small molecule completed

    1 trial
  42. Tipifarnib

    Kura Oncology

    Myelodysplastic Syndromes

    phase 2 small molecule terminated

    1 trial
  43. Tipifarnib

    Kura Oncology

    Thyroid Cancer

    phase 2 small molecule completed

    1 trial
  44. Tipranavir

    Boehringer Ingelheim

    HIV Infections

    phase 2 small molecule completed

    1 trial
  45. Tiragolumab

    Hoffmann-La Roche

    Cervical Cancer

    phase 2 small molecule completed

    1 trial
  46. Tiragolumab for HNSCC, metastatic deficient mis…

    Disc Medicine

    HNSCC, metastatic deficient mismatch repair (dMMR)/MSI-high (MSI-H) tumors, irresectable or metastatic melanoma, locally advanced or metastatic solid tumor

    phase 2 small molecule active

    1 trial
  47. Tiratricol

    Ultragenyx UK Limited

    Allan-Herndon-Dudley Syndrome

    phase 2 small molecule active

    1 trial
  48. Tiratricol, Tiratricol

    Rare Thyroid Therapeutics International AB

    Monocarboxylate Transporter 8 (MCT8) deficiency

    phase 2 small molecule active

    1 trial

Frequently asked questions

How many Phase II pipeline programs are in the directory?

7,238 published programs match this development stage in our ClinicalTrials.gov index.

What defines this pipeline stage?

Phase and status reflect ClinicalTrials.gov registry fields at last sync. See our clinical trial phases reference for methodology.