Saturday, July 11, 2026

Intelligence · Clinical pipeline

Phase II Pipeline Programs

Proof-of-concept and dose-finding clinical programs in Phase II development.

Programs 7,238
Sponsors 1,771
Drugs 4,798

Quick answer

NovaPharmaNews tracks 7,238 phase ii pharmaceutical pipeline programs from ClinicalTrials.gov. Proof-of-concept and dose-finding clinical programs in Phase II development.

Top sponsors

Pipeline programs

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  1. TGRX-326

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Non-small Cell Lung Cancer

    phase 2 small molecule active

    1 trial
  2. THALASSA 2.0

    MEDA Pharma GmbH & Co. KG

    post-COVID-19 Condition (PCC)

    phase 2 small molecule active

    1 trial
  3. THC

    BRIGHT MINDS BIOSCIENCES INC.

    THC

    phase 2 small molecule active

    1 trial
  4. THIO-101

    MAIA Biotechnology

    Non-Small Cell Lung Cancer

    phase 2 small molecule active

    1 trial
  5. THOR-707

    Sanofi Pasteur

    Metastasis

    phase 2 small molecule terminated

    1 trial
  6. THOR-707

    Sanofi Pasteur

    Malignant Melanoma

    phase 2 small molecule terminated

    1 trial
  7. THYMOGLOBULINE for haematological malignancies

    The George Institute

    haematological malignancies

    phase 2 small molecule active

    1 trial
  8. TIMP-GLIA

    Takeda

    Celiac Disease

    phase 2 small molecule completed

    2 trials
  9. TISAGENLECLEUCEL

    Novartis Pharmaceuticals

    High-risk B-cell acute lymphoblastic leukemia

    phase 2 small molecule active

    1 trial
  10. TISAGENLECLEUCEL

    Novartis Pharmaceuticals

    Adult patients with refractory or relapsed follicular lymphoma

    phase 2 small molecule active

    1 trial
  11. TISLELIZUMAB

    Fondazione Telethon ETS

    Hodgkin lymphoma

    phase 2 small molecule active

    1 trial
  12. TKM-080301

    Arbutus Biopharma Corp

    Cancer

    phase 2 small molecule completed

    1 trial
  13. TKM-080301

    Arbutus Biopharma Corp

    Hepatocellular Carcinoma

    phase 2 small molecule completed

    1 trial
  14. TL-895, TL-895

    Lacuna Pharma Pty Ltd

    B Cell Malignancies and Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma

    phase 2 small molecule active

    1 trial
  15. TL-895-201

    Lacuna Pharma Pty Ltd

    Indolent Systemic Mastocytosis

    phase 2 small molecule active

    1 trial
  16. TMC207

    BRIGHT MINDS BIOSCIENCES INC.

    Pulmonary Tuberculosis

    phase 2 small molecule completed

    1 trial
  17. TMC207

    Janssen Cilag International NV

    Tuberculosis

    phase 2 small molecule completed

    1 trial
  18. TMC207 (J)

    BRIGHT MINDS BIOSCIENCES INC.

    Pulmonary Tuberculosis

    phase 2 small molecule completed

    1 trial
  19. TMC435

    Elan Pharma International

    Hepatitis C

    phase 2 small molecule completed

    1 trial
  20. TMP-08012024-3

    Lacuna Pharma Pty Ltd

    Chronic spontaneous urticaria

    phase 2 small molecule active

    1 trial
  21. TMP-18122023-58

    Lacuna Pharma Pty Ltd

    Adults with ADHD and moderate to severe depression

    phase 2 small molecule active

    1 trial
  22. TN-201

    Tenaya Therapeutics

    Hypertrophic Cardiomyopathy

    phase 2 gene therapy active

    1 trial
  23. TNFα Monoclonal Antibody

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Spinal Cord Injuries

    phase 2 small molecule active

    1 trial
  24. TNG260

    Tango Therapeutics

    Non Small Cell Lung Cancer

    phase 2 small molecule active

    1 trial
  25. TNG348

    Tango Therapeutics

    Breast Cancer

    phase 2 small molecule terminated

    1 trial
  26. TNG456

    Tango Therapeutics

    Non Small Cell Lung Cancer

    phase 2 small molecule active

    1 trial
  27. TNG462

    Revolution Medicines

    PDAC

    phase 2 small molecule active

    1 trial
  28. TNG462

    Tango Therapeutics

    Locally Advanced Solid Tumor

    phase 2 small molecule active

    1 trial
  29. TNG908

    Tango Therapeutics

    Locally Advanced Solid Tumor

    phase 2 small molecule terminated

    1 trial
  30. TNG908-C101

    Tango Therapeutics

    "Ph1: •Locally advanced (LA) or metastatic MTAP-deleted (met.MTAP-del.) solid tumors •MTAP-del.relapsed or refrac. Grade 4 astrocytoma or glioblastoma multiforme (R/R GBM) Ph2: A1:LA or met.MTAP-del. squamous and nonsquamous NSCLC A2:LA or met.MTAP-del. mesothelioma A3:LA or met.MTAP-del. sarcoma A4:LA or met.MTAP-del. pancreatic ductal adenocarcinoma or adenosquamous carcinoma w/predominantly adenocarcinoma histology A5:Other LA or met.MTAP-del. solid tumors A6:MTAP-del. R/R GBM"

    phase 2 small molecule active

    1 trial
  31. TNT-OES-2

    Disc Medicine

    oesophageal cancer, oesophagogastric junction cancer

    phase 2 small molecule active

    1 trial
  32. TNTL capsule

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Accidental Exposure While Preparing Drug for Administration

    phase 2 small molecule completed

    1 trial
  33. TNX-102 SL

    Tonix Pharmaceuticals Holding

    Post-Acute Sequelae of SARS-CoV-2 (PASC) Infection

    phase 2 small molecule completed

    1 trial
  34. TNX-1300

    Tonix Pharmaceuticals Holding

    Cocaine Intoxication

    phase 2 small molecule terminated

    1 trial
  35. TNX-1300 (Injection)

    BRIGHT MINDS BIOSCIENCES INC.

    Cocaine Use

    phase 2 small molecule terminated

    1 trial
  36. TNX-1500

    Tonix Pharmaceuticals Holding

    Kidney Transplant

    phase 2 small molecule active

    1 trial
  37. TNX-1900

    Tonix Pharmaceuticals Holding

    Chronic Migraine

    phase 2 small molecule completed

    1 trial
  38. TNX-201

    Tonix Pharmaceuticals Holding

    Tension-Type Headache

    phase 2 small molecule completed

    1 trial
  39. TNX-601 ER

    Tonix Pharmaceuticals Holding

    Depression

    phase 2 small molecule completed

    1 trial
  40. TOCILIZUMAB for Mantle Cell Lymphoma

    Fondazione Telethon ETS

    Mantle Cell Lymphoma

    phase 2 small molecule active

    1 trial
  41. TOP-N53-02

    Lacuna Pharma Pty Ltd

    Digital ulcers in systemic sclerosis

    phase 2 small molecule active

    1 trial
  42. TOPIRAMATE

    Disc Medicine

    human immunodeficiency virus 1 (HIV-1)

    phase 2 small molecule active

    1 trial
  43. TOUR006-T01

    Tour Hekla

    Thyroid Eye Disease

    phase 2 small molecule active

    1 trial
  44. TP-03

    Tarsus Pharmaceuticals

    Meibomian Gland Dysfunction

    phase 2 small molecule completed

    1 trial
  45. TP-05 (lotilaner) Low Dose

    Tarsus Pharmaceuticals

    Lyme Disease

    phase 2 small molecule active

    1 trial
  46. TP-38

    Teva Pharma GmbH

    Glioblastoma Multiforme

    phase 2 small molecule completed

    1 trial
  47. TP-38

    Teva Pharma GmbH

    Recurrent Glioblastoma Multiforme

    phase 2 small molecule completed

    1 trial
  48. TPC induction chemotherapy

    Sun Yat-sen University

    Nasopharyngeal Carcinoma

    phase 2 small molecule active

    1 trial

Frequently asked questions

How many Phase II pipeline programs are in the directory?

7,238 published programs match this development stage in our ClinicalTrials.gov index.

What defines this pipeline stage?

Phase and status reflect ClinicalTrials.gov registry fields at last sync. See our clinical trial phases reference for methodology.