Saturday, July 11, 2026

Intelligence · Clinical pipeline

Phase II Pipeline Programs

Proof-of-concept and dose-finding clinical programs in Phase II development.

Programs 7,238
Sponsors 1,771
Drugs 4,798

Quick answer

NovaPharmaNews tracks 7,238 phase ii pharmaceutical pipeline programs from ClinicalTrials.gov. Proof-of-concept and dose-finding clinical programs in Phase II development.

Top sponsors

Pipeline programs

Page 122 of 151
  1. Soquelitinib

    Corvus Pharmaceuticals

    Atopic Dermatitis

    phase 2 small molecule active

    2 trials
  2. Sorafenib

    United Therapeutics Europe Ltd

    Lung Cancer

    phase 2 small molecule completed

    1 trial
  3. Sorafenib (Nexavar, BAY43-9006) plus Doxorubicin

    Bayer HealthCare AG

    Carcinoma, Hepatocellular

    phase 2 small molecule completed

    1 trial
  4. Sotagliflozin

    LEXICON PHARMACEUTICALS, INC.

    Type 1 Diabetes

    phase 2 small molecule active

    2 trials
  5. Sotagliflozin

    LEXICON PHARMACEUTICALS, INC.

    Cardiac Failure Aggravated

    phase 2 small molecule terminated

    1 trial
  6. Soticlestat

    Takeda

    Complex Regional Pain Syndrome

    phase 2 small molecule completed

    1 trial
  7. Soticlestat

    Takeda

    15q Duplication Syndrome

    phase 2 small molecule completed

    1 trial
  8. Soticlestat

    Takeda

    Epilepsy

    phase 2 small molecule terminated

    1 trial
  9. Sotrovimab

    Vir Biotechnology

    COVID-19

    phase 2 mab terminated

    1 trial
  10. Sotrovimab (Gen1)

    Vir Biotechnology

    Covid19

    phase 2 mab completed

    1 trial
  11. Sparsentan

    Travere Therapeutics

    ANCA Associated Vasculitis

    phase 2 small molecule active

    1 trial
  12. Spermidine

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Radiation-induced Xerostomia

    phase 2 small molecule active

    1 trial
  13. Spesolimab

    Boehringer Ingelheim

    Generalized Pustular Psoriasis

    phase 2 small molecule active

    1 trial
  14. Spironolactone 25mg

    Hospital Authority, Hong Kong

    Atrial Fibrillation

    phase 2 small molecule active

    1 trial
  15. Splinting

    United Therapeutics Europe Ltd

    Hand Osteoarthritis

    phase 2 other completed

    1 trial
  16. Spray of spirulina derivatives

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Radiation-induced Oral Mucositis

    phase 2 small molecule active

    1 trial
  17. Stanate

    Mallinckrodt Pharmaceuticals Ireland Limited

    Hyperbilirubinemia

    phase 2 small molecule completed

    1 trial
  18. Standard Cognitive Behavioral Treatment

    BRIGHT MINDS BIOSCIENCES INC.

    Substance-Related Disorders

    phase 2 other completed

    1 trial
  19. Standard Treatment As Usual (TAU)

    BRIGHT MINDS BIOSCIENCES INC.

    Substance Abuse

    phase 2 other completed

    1 trial
  20. Standard drug counseling

    BRIGHT MINDS BIOSCIENCES INC.

    Opiate Dependence

    phase 2 other completed

    1 trial
  21. Standard intervention (counseling + self-help written materials)

    BRIGHT MINDS BIOSCIENCES INC.

    Tobacco Use

    phase 2 other completed

    1 trial
  22. Standard lymphodepletion regimen

    Kyverna Therapeutics

    Stiff-Person Syndrome

    phase 2 mab active

    1 trial
  23. Standard of Care with Lofexidine

    BRIGHT MINDS BIOSCIENCES INC.

    Opioid Withdrawal (Disorder)

    phase 2 small molecule active

    1 trial
  24. Standard of care and PrEP Choice at Enrollment

    BRIGHT MINDS BIOSCIENCES INC.

    HIV

    phase 2 other active

    1 trial
  25. Stellate Ganglion Block injection with ropivicane

    United Therapeutics Europe Ltd

    Post Traumatic Stress Disorder (PTSD)

    phase 2 other completed

    1 trial
  26. Stem Cell Educator

    The First People's Hospital of Lianyungang

    Alopecia Areata

    phase 2 other active

    1 trial
  27. Stem cell infusion

    Lxo Ireland Designated Activity Company

    Critical Limb Ischemia (CLI)

    phase 2 small molecule terminated

    1 trial
  28. Stem cells

    Takeda

    Rheumatoid Arthritis Aggravated

    phase 2 gene therapy completed

    1 trial
  29. Steroids switch

    United Therapeutics Europe Ltd

    Prostate Cancer

    phase 2 small molecule completed

    1 trial
  30. Stivarga 40 mg film-coated tablets

    Ningbo Cancer Hospital

    Bone sarcoma

    phase 2 small molecule active

    1 trial
  31. Stivarga 40 mg film-coated tablets

    Istituto Gentili S.r.l.

    grade 1, 2 and 3 meningioma

    phase 2 small molecule active

    1 trial
  32. Streptococcus salivarius K12

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Head and Neck Squamous Cell Carcinoma

    phase 2 small molecule completed

    1 trial
  33. Stromal-vascular fraction

    Century Therapeutics

    Knee Osteoarthritis

    phase 2 mab active

    1 trial
  34. Study 3: Chronic care management

    BRIGHT MINDS BIOSCIENCES INC.

    Smoking, Tobacco

    phase 2 other completed

    1 trial
  35. Sub-tenon injection of saline followed by a sub-tenon injection of aflibercept

    Regeneron UK Limited

    Thyroid Eye Disease

    phase 2 small molecule completed

    1 trial
  36. Subcutaneous injection of TAK-850

    Takeda

    Influenza Infection

    phase 2 small molecule completed

    1 trial
  37. Sublingual film containing Dexmedetomidine

    BioXcel Therapeutics

    Agitation,Psychomotor

    phase 2 small molecule completed

    1 trial
  38. Suboxone Remote Observed Dosing

    BRIGHT MINDS BIOSCIENCES INC.

    Opioid-use Disorder

    phase 2 other completed

    1 trial
  39. Sugammadex Injection 2mg/kg

    BRIGHT MINDS BIOSCIENCES INC.

    Anesthesia, General

    phase 2 small molecule completed

    1 trial
  40. Sunvozertinib

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Potentially Resectable EGFR Exon 20 Insertion Non-Small Cell Lung Cancer

    phase 2 small molecule active

    1 trial
  41. Sunvozertinib, Sunvozertinib

    Lacuna Pharma Pty Ltd

    Non-Small Cell Lung Cancer

    phase 2 small molecule active

    1 trial
  42. Surgery

    Ultragenyx UK Limited

    Spastic Diplegia

    phase 2 other active

    1 trial
  43. Surufatinib

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Biliary Tract Cancer

    phase 2 small molecule active

    1 trial
  44. Surufatinib + Serplulimab+Albumin-paclitaxel + Gemcitabine

    Sun Yat-sen University

    Locally Advanced Pancreatic Cancer

    phase 2 small molecule active

    1 trial
  45. Surzebiclimab

    BeiGene

    Locally Advanced or Metastatic Solid Tumors for Phase 1, Dose Escalation and Phase 2 Safety Lead-in

    phase 2 small molecule completed

    1 trial
  46. Surzebiclimab

    BEONE MEDICINES AUS PTY LTD

    Locally Advanced or Metastatic Solid Tumors for Phase 1, Dose Escalation and Phase 2 Safety Lead-in

    phase 2 small molecule completed

    1 trial
  47. Suspension of autologous mononuclear cells separated from bone marrow aspirate

    The George Institute

    chronic limb-threatening ischemia, diabetic foot ulcers

    phase 2 small molecule active

    1 trial
  48. Sustanon 250, solution injectable

    The George Institute

    Androgen deficiency, palliative care

    phase 2 small molecule active

    1 trial

Frequently asked questions

How many Phase II pipeline programs are in the directory?

7,238 published programs match this development stage in our ClinicalTrials.gov index.

What defines this pipeline stage?

Phase and status reflect ClinicalTrials.gov registry fields at last sync. See our clinical trial phases reference for methodology.