Saturday, July 11, 2026

Intelligence · Clinical pipeline

Phase II Pipeline Programs

Proof-of-concept and dose-finding clinical programs in Phase II development.

Programs 7,238
Sponsors 1,771
Drugs 4,798

Quick answer

NovaPharmaNews tracks 7,238 phase ii pharmaceutical pipeline programs from ClinicalTrials.gov. Proof-of-concept and dose-finding clinical programs in Phase II development.

Top sponsors

Pipeline programs

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  1. Rilzabrutinib

    Sanofi-aventis Healthcare Pty Ltd

    Warm autoimmune hemolytic anemia

    phase 2 small molecule active

    1 trial
  2. Rilzabrutinib

    Lacuna Pharma Pty Ltd

    Immune Thrombocytopenia

    phase 2 small molecule active

    1 trial
  3. Rilzabrutinib, Rilzabrutinib

    Sanofi-aventis Healthcare Pty Ltd

    Immune system diseases

    phase 2 small molecule active

    1 trial
  4. Rimonabant

    BRIGHT MINDS BIOSCIENCES INC.

    Schizophrenia

    phase 2 small molecule terminated

    1 trial
  5. Risperidone

    BRIGHT MINDS BIOSCIENCES INC.

    Cocaine-Related Disorders

    phase 2 small molecule terminated

    6 trials
  6. Risperidone

    Indivior Pty Ltd

    Schizophrenia

    phase 2 small molecule completed

    1 trial
  7. Ritanserin

    BRIGHT MINDS BIOSCIENCES INC.

    Cocaine-Related Disorders

    phase 2 small molecule completed

    1 trial
  8. Ritonavir

    Abbott Australasia Pty Ltd

    Sarcoma, Kaposi

    phase 2 small molecule completed

    1 trial
  9. Rituximab

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Immune Thrombocytopenia

    phase 2 small molecule active

    1 trial
  10. Rituximab

    United Therapeutics Europe Ltd

    Fatigue

    phase 2 mab completed

    1 trial
  11. Rituximab

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Severe Aplastic Anemia

    phase 2 small molecule active

    1 trial
  12. Rituximab

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Diffuse Large B Cell Lymphoma

    phase 2 small molecule active

    1 trial
  13. Rituximab

    BEONE MEDICINES AUS PTY LTD

    Chronic Lymphocytic Leukemia

    phase 2 mab active

    1 trial
  14. Rituximab Paclitaxel Ruxolitinib

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Refractory Diffuse Large B-cell Lymphoma

    phase 2 small molecule active

    1 trial
  15. Rituximab combined with Daratumumab(Anti-CD38 Monoclonal Antibody)

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Immune Thrombocytopenia

    phase 2 small molecule active

    1 trial
  16. Rocatinlimab

    Amgen

    Asthma

    phase 2 small molecule active

    1 trial
  17. Roflumilast

    Arcutis Biotherapeutics

    Plaque Psoriasis

    phase 2 small molecule completed

    1 trial
  18. Roflumilast

    Takeda

    Chronic Obstructive Pulmonary Disease

    phase 2 small molecule terminated

    1 trial
  19. Roflumilast Cream 0.05%

    Arcutis Biotherapeutics

    Atopic Dermatitis

    phase 2 small molecule completed

    1 trial
  20. Roflumilast Cream 0.3%

    Arcutis Biotherapeutics

    Plaque Psoriasis

    phase 2 small molecule completed

    1 trial
  21. Roflumilast Foam 0.3%

    Arcutis Biotherapeutics

    Seborrheic Dermatitis

    phase 2 small molecule completed

    1 trial
  22. Roflumilast foam 0.3%

    Arcutis Biotherapeutics

    Plaque Psoriasis

    phase 2 small molecule completed

    1 trial
  23. Roflumilast topical 0.3% foam

    Arcutis Biotherapeutics

    Non-segmental Vitiligo

    phase 2 small molecule active

    1 trial
  24. Roginolisib

    United Therapeutics Europe Ltd

    Leukemia

    phase 2 small molecule active

    1 trial
  25. Romidepsin

    Fondazione Telethon ETS

    Anaplastic Large T-cell Lymphoma ALK negative, Angioimmunoblastic T-cell Lymphoma, Peripheral T-cell lymphoma, NOS

    phase 2 small molecule active

    1 trial
  26. Romidepsin

    Takeda

    Lymphoma, T-Cell, Peripheral

    phase 2 small molecule terminated

    1 trial
  27. Romiplostim

    The First People's Hospital of Lianyungang

    MDS (Myelodysplastic Syndrome)

    phase 2 small molecule active

    1 trial
  28. Romiplostim

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Immune Thrombocytopenia (ITP)

    phase 2 small molecule completed

    1 trial
  29. Romiplostim N01

    Hospital Authority, Hong Kong

    Chemotherapy-induced Thrombocytopenia

    phase 2 small molecule active

    1 trial
  30. Ropidoxuridine

    Shuttle Pharmaceuticals Holdings

    Glioblastoma, IDH-wildtype

    phase 2 small molecule terminated

    1 trial
  31. Ropivacaine injection

    United Therapeutics Europe Ltd

    Stress Disorders, Post-Traumatic

    phase 2 small molecule active

    2 trials
  32. Rostafuroxin

    WINDTREE THERAPEUTICS INC /DE/

    Hypertension

    phase 2 small molecule completed

    1 trial
  33. Rotarix™

    GlaxoSmithKline

    Infections, Rotavirus

    phase 2 mab completed

    1 trial
  34. Rotigotine Transdermal System [Neupro]

    BRIGHT MINDS BIOSCIENCES INC.

    Substance-Related Disorders

    phase 2 small molecule active

    1 trial
  35. Routine Template-based lymphadenectomy

    The First People's Hospital of Lianyungang

    Lymph Node Dissection

    phase 2 other active

    1 trial
  36. Roxadustat

    Peking University Third Hospital

    Coronary Artery Bypass

    phase 2 small molecule terminated

    1 trial
  37. Rozlytrek 200 mg hard capsules

    Hoffmann-La Roche

    Locally Advanced or Metastatic Solid Tumors that Harbor NTRK1/2/3, ROS1, or ALK Gene Rearrangements

    phase 2 small molecule active

    1 trial
  38. Rucaparib

    United Therapeutics Europe Ltd

    Cervical Cancer

    phase 2 small molecule terminated

    1 trial
  39. RuxoTam; A phase II study to evaluate safety... for Myelofibrosis

    Disc Medicine

    Myelofibrosis

    phase 2 other active

    1 trial
  40. Ruxolitinib

    The First People's Hospital of Lianyungang

    Bronchiolitis Obliterans Syndrome

    phase 2 small molecule active

    1 trial
  41. Ruxolitinib

    ACTUATE THERAPEUTICS, INC.

    Myelofibrosis

    phase 2 small molecule completed

    1 trial
  42. Ruxolitinib

    RIGEL PHARMACEUTICALS INC

    Coronavirus

    phase 2 small molecule completed

    1 trial
  43. Ruxolitinib

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    aGVHD

    phase 2 small molecule completed

    1 trial
  44. Ruxolitinib 5 MG BID Oral Tablet

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    The Prophylactic Value of Ruxolitinib for aGVHD in HSCT Recipients of AA

    phase 2 small molecule active

    1 trial
  45. S-1

    United Therapeutics Europe Ltd

    Locally Advanced or Metastatic Pancreatic Cancer

    phase 2 small molecule completed

    1 trial
  46. S-1

    United Therapeutics Europe Ltd

    Advanced Non-Small Cell Lung Cancer

    phase 2 small molecule completed

    2 trials
  47. S-337395

    Shionogi B.V.

    Respiratory Syncytial Virus Infections

    phase 2 small molecule active

    1 trial
  48. S-606001 matching placebo, S-606001

    Shionogi B.V.

    Late-onset Pompe disease.

    phase 2 small molecule active

    1 trial

Frequently asked questions

How many Phase II pipeline programs are in the directory?

7,238 published programs match this development stage in our ClinicalTrials.gov index.

What defines this pipeline stage?

Phase and status reflect ClinicalTrials.gov registry fields at last sync. See our clinical trial phases reference for methodology.