Saturday, July 11, 2026

Intelligence · Clinical pipeline

Phase II Pipeline Programs

Proof-of-concept and dose-finding clinical programs in Phase II development.

Programs 7,238
Sponsors 1,771
Drugs 4,798

Quick answer

NovaPharmaNews tracks 7,238 phase ii pharmaceutical pipeline programs from ClinicalTrials.gov. Proof-of-concept and dose-finding clinical programs in Phase II development.

Top sponsors

Pipeline programs

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  1. Psilocybin

    Compass Therapeutics

    Body Dysmorphic Disorders

    phase 2 small molecule completed

    1 trial
  2. Psilocybin

    Compass Therapeutics

    Post Traumatic Stress Disorder

    phase 2 small molecule completed

    1 trial
  3. Psilocybin

    Compass Therapeutics

    Treatment-Resistant Major Depressive Disorder

    phase 2 small molecule terminated

    1 trial
  4. Psilocybin (Usona Institute)

    United Therapeutics Europe Ltd

    Spinal Cord Injury

    phase 2 small molecule active

    1 trial
  5. Pucotenlimab

    Zhejiang Provincial People's Hospital

    Pancreatic Cancer

    phase 2 mab active

    1 trial
  6. Pucotenlimab

    Sun Yat-sen University

    Colorectal Cancer (CRC)

    phase 2 small molecule active

    1 trial
  7. Pulmonary Rehabilitation (PR)

    United Therapeutics Europe Ltd

    Non-small Cell Lung Cancer Stage III

    phase 2 other active

    1 trial
  8. Pumecitinib Nasal Spray 0.3%

    Prime Medicine

    Seasonal Allergic Rhinitis

    phase 2 small molecule active

    1 trial
  9. Purified Inactivated Zika Virus Vaccine (PIZV)

    Takeda

    Healthy Volunteers

    phase 2 mab terminated

    1 trial
  10. Purified Vero Rabies Vaccine Serum Free (VRVg)

    Sanofi Pasteur

    Rabies

    phase 2 mab completed

    1 trial
  11. PvCS/Montanide ISA-51 VG Vaccine

    BRIGHT MINDS BIOSCIENCES INC.

    Plasmodium Vivax Malaria

    phase 2 mab active

    1 trial
  12. Pyrotinib

    The First People's Hospital of Lianyungang

    Breast Cancer

    phase 2 small molecule active

    1 trial
  13. QAMS-containing PMMA

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Oral Health

    phase 2 other completed

    1 trial
  14. QBW251

    Novartis Pharmaceuticals

    Pulmonary Disease, Chronic Obstructive

    phase 2 small molecule completed

    1 trial
  15. QGC001

    Quantum Biopharma

    Hypertension

    phase 2 small molecule completed

    1 trial
  16. QGC001

    Quantum Biopharma

    Heart Failure

    phase 2 small molecule terminated

    1 trial
  17. QGC001

    Quantum Biopharma

    Essential Hypertension

    phase 2 small molecule completed

    1 trial
  18. QINLOCK 50 mg tablets

    Lacuna Pharma Pty Ltd

    Advanced gastrointestinal stromal tumor (GIST)

    phase 2 small molecule active

    1 trial
  19. QL1706

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Platinum-resistant Recurrent Ovarian Cancer

    phase 2 small molecule active

    1 trial
  20. QL1706

    The First People's Hospital of Lianyungang

    Local Advanced Esophageal Cancer

    phase 2 small molecule active

    1 trial
  21. QL1706 (Iparomlimab/Tuvonralimab)

    The First People's Hospital of Lianyungang

    Gastric Cancer Stage III

    phase 2 small molecule active

    1 trial
  22. QL1706 (bispecific antibody targeting PD-1 and CLTA-4)

    The First People's Hospital of Lianyungang

    Esophageal Squamous Cell Carcinoma (ESCC)

    phase 2 small molecule active

    1 trial
  23. QL1706-2025-086

    The First People's Hospital of Lianyungang

    Cervical Cancer Stage IVA

    phase 2 other active

    1 trial
  24. QR-010

    ProQR Therapeutics N.V.

    Cystic Fibrosis

    phase 2 small molecule completed

    2 trials
  25. QR-1123

    ProQR Therapeutics N.V.

    Autosomal Dominant Retinitis Pigmentosa

    phase 2 small molecule active

    1 trial
  26. QR-421a

    ProQR Therapeutics N.V.

    Retinitis Pigmentosa

    phase 2 small molecule completed

    1 trial
  27. QTORIN 3.9% rapamycin anhydrous gel

    PALVELLA THERAPEUTICS, INC.

    Cutaneous Venous Malformations

    phase 2 small molecule active

    1 trial
  28. QUILT-2.005

    Immunitybio Ireland Limited

    Non-Muscle Invasive Bladder Cancer

    phase 2 small molecule active

    1 trial
  29. QUINTIS

    The George Institute

    Metastatic Colorectal Cancer without liver metastases

    phase 2 small molecule active

    1 trial
  30. Qinbudan

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Pulmonary Tuberculosis

    phase 2 small molecule completed

    1 trial
  31. Qingying oral liquid and modified Da Huang-Huang Lian Xiexin mouthwash

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Radiation-induced Oral Mucositis

    phase 2 small molecule active

    1 trial
  32. Qishen Granules

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Heart Failure

    phase 2 small molecule active

    1 trial
  33. Qizhi weitong granules(High)

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Irritable Bowel Syndrome

    phase 2 small molecule active

    1 trial
  34. Quadriceps strength training

    Hospital Authority, Hong Kong

    Patellofemoral Pain Syndrome

    phase 2 other active

    1 trial
  35. Quadrivalent influenza vaccine

    Green Valley (Shanghai) Pharmaceuticals Co.,

    Influenza

    phase 2 mab completed

    1 trial
  36. Quemliclustat

    Arcus Biosciences

    Oligometastatic Prostate Cancer

    phase 2 small molecule active

    1 trial
  37. Quetiapine

    BRIGHT MINDS BIOSCIENCES INC.

    Cannabis Dependence

    phase 2 small molecule completed

    1 trial
  38. QuitAdvisorMD Software Algorithm

    BRIGHT MINDS BIOSCIENCES INC.

    Smoking

    phase 2 other active

    1 trial
  39. Quizartinib

    AXIM BIOTECHNOLOGIES, INC.

    newly diagnosed pediatric FLT3-ITD positive and NPM1 wild-type AML

    phase 2 small molecule active

    1 trial
  40. Quizartinib

    Daiichi Sankyo

    Acute Myeloid Leukemia

    phase 2 small molecule active

    1 trial
  41. Qutenza

    United Therapeutics Europe Ltd

    Pulmonary Hypertension

    phase 2 small molecule completed

    1 trial
  42. Qutenza (8% capsaicin)

    United Therapeutics Europe Ltd

    Pulmonary Hypertension

    phase 2 small molecule completed

    1 trial
  43. R-EPOCH in Combination With Ibrutinib

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Richter Transformation

    phase 2 small molecule active

    1 trial
  44. R01DA029050

    BRIGHT MINDS BIOSCIENCES INC.

    Drug Abuse

    phase 2 other completed

    1 trial
  45. R10597-ONC-22114

    Lacuna Pharma Pty Ltd

    Melanoma, Advanced Solid Tumours, Clear-Cell Renal-Cell Carcinoma (ccRCC)

    phase 2 small molecule active

    1 trial
  46. R13335-PAH-2365

    Lacuna Pharma Pty Ltd

    Pulmonary Arterial Hypertension (PAH)

    phase 2 small molecule active

    1 trial
  47. R1979-ONC-1625

    Lacuna Pharma Pty Ltd

    B-cell non-Hodgkin lymphoma (NHL)

    phase 2 small molecule active

    1 trial
  48. R2810-ONC-2045

    Lacuna Pharma Pty Ltd

    Advanced Non-Small Cell Lung Cancer

    phase 2 small molecule active

    1 trial

Frequently asked questions

How many Phase II pipeline programs are in the directory?

7,238 published programs match this development stage in our ClinicalTrials.gov index.

What defines this pipeline stage?

Phase and status reflect ClinicalTrials.gov registry fields at last sync. See our clinical trial phases reference for methodology.