Saturday, July 11, 2026

Intelligence · Clinical pipeline

Phase II Pipeline Programs

Proof-of-concept and dose-finding clinical programs in Phase II development.

Programs 7,238
Sponsors 1,771
Drugs 4,798

Quick answer

NovaPharmaNews tracks 7,238 phase ii pharmaceutical pipeline programs from ClinicalTrials.gov. Proof-of-concept and dose-finding clinical programs in Phase II development.

Top sponsors

Pipeline programs

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  1. Ponatinib

    Takeda

    Pediatric Philadelphia Chromosome-positive Acute Lymphoblastic Leukemia (Ph+ALL)

    phase 2 small molecule terminated

    1 trial
  2. Ponatinib

    Takeda

    Myeloid Leukemia, Chronic, Chronic Phase

    phase 2 small molecule completed

    1 trial
  3. Ponatinib

    Takeda

    Chronic Myeloid Leukemia

    phase 2 small molecule completed

    1 trial
  4. Population Council #323

    United Therapeutics Europe Ltd

    Contraception

    phase 2 small molecule completed

    1 trial
  5. Postoperative adjuvant lenvatinib

    The First People's Hospital of Lianyungang

    Hepatocellular Carcinoma (HCC)

    phase 2 small molecule active

    1 trial
  6. Povetacicept

    Vertex Pharmaceuticals (Australia) Pty.

    Myasthenia Gravis, Generalized

    phase 2 small molecule active

    1 trial
  7. Praliciguat

    Akebia Europe Limited

    Focal Segmental Glomerulosclerosis

    phase 2 small molecule active

    1 trial
  8. Pramlintide+Metreleptin

    Takeda

    Obesity

    phase 2 small molecule terminated

    1 trial
  9. Prazosin

    BRIGHT MINDS BIOSCIENCES INC.

    Continuous Methamphetamine Abuse

    phase 2 small molecule completed

    1 trial
  10. Pre-Quit Nicotine Lozenges

    BRIGHT MINDS BIOSCIENCES INC.

    Smoking Cessation

    phase 2 small molecule completed

    1 trial
  11. Pre-operative chemotherapy

    Nanjing Zenshine Pharmaceuticals

    Gastric Cancers

    phase 2 small molecule active

    1 trial
  12. Pre-operative chemotherapy

    The First People's Hospital of Lianyungang

    Non-small Cell Lung Cancer

    phase 2 small molecule active

    1 trial
  13. PreSave

    Fondazione Telethon ETS

    Muscle-Invasive Bladder cancer

    phase 2 small molecule active

    1 trial
  14. Precision Cells

    Ningbo Cancer Hospital

    Precision Cell Immunotherapy

    phase 2 mab active

    1 trial
  15. Prednisone

    Nanjing Children's Hospital

    Henoch-Schoenlein Purpura Nephritis

    phase 2 small molecule active

    1 trial
  16. Prednisone

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Langerhans Cell Histiocytosis of Bone

    phase 2 small molecule active

    1 trial
  17. Prednisone + Jakavi(ruxolitinib)

    Yung NA

    GVHD - Graft-Versus-Host Disease

    phase 2 small molecule active

    1 trial
  18. Pregabalin

    Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University

    Neuropathic Pain

    phase 2 small molecule completed

    1 trial
  19. Premier Lifestyle Intervention with DASH Diet

    NORTHWEST BIOTHERAPEUTICS INC

    Weight Loss

    phase 2 other completed

    1 trial
  20. Preoperative lanreotide treatment

    The First People's Hospital of Lianyungang

    Acromegaly

    phase 2 small molecule active

    1 trial
  21. Presatovir

    Gilead Sciences Ireland UC

    Respiratory Syncytial Virus

    phase 2 small molecule completed

    1 trial
  22. Preservative-free, ophthalmic solution

    Laboratoire HRA Pharma

    Paediatric myopia

    phase 2 small molecule active

    1 trial
  23. PrimeC

    NeuroSense Therapeutics

    Amyotrophic Lateral Sclerosis

    phase 2 small molecule completed

    1 trial
  24. PrimeC

    NeuroSense Therapeutics

    Alzheimer Disease

    phase 2 small molecule terminated

    1 trial
  25. Pro insulin peptide

    Cardiff Oncology

    Type 1 Diabetes

    phase 2 small molecule completed

    1 trial
  26. ProHema-CB

    Zafatek

    Hematologic Malignancies

    phase 2 mab terminated

    1 trial
  27. ProSpare

    United Therapeutics Europe Ltd

    Cancer

    phase 2 other active

    1 trial
  28. ProTmune

    Zafatek

    Hematologic Malignancies

    phase 2 mab completed

    1 trial
  29. Probiotics Compound (Biolosion)

    Sun Yat-sen University

    Advanced Urothelial Carcinoma

    phase 2 small molecule active

    1 trial
  30. Prodige 54 SAMCO

    CERO THERAPEUTICS HOLDINGS, INC.

    COLORECTAL METASTATIC CANCER WITH MICROSATELLITE INSTABILITY

    phase 2 small molecule active

    1 trial
  31. Product

    Novo Nordisk A/S

    Women with an indication for IVF/ICSI

    phase 2 small molecule active

    1 trial
  32. Progesterone

    BRIGHT MINDS BIOSCIENCES INC.

    Cannabis Use

    phase 2 small molecule completed

    1 trial
  33. Progesterone

    BRIGHT MINDS BIOSCIENCES INC.

    Tobacco Use Disorder

    phase 2 small molecule completed

    1 trial
  34. Programmed Cell Death Protein 1 Inhibitor

    Chinese University of Hong Kong

    Locally Advanced Esophageal Squamous Cell Carcinoma

    phase 2 small molecule active

    1 trial
  35. Proleukin

    BRIGHT MINDS BIOSCIENCES INC.

    Alzheimer Disease

    phase 2 small molecule active

    1 trial
  36. Proleukin 18 x 106 IE Poeder voor oplossing voor injectie of infusie

    Disc Medicine

    MDS with excess blasts, MDS/AML or AML patients

    phase 2 small molecule active

    1 trial
  37. Propranolol

    BRIGHT MINDS BIOSCIENCES INC.

    Cocaine Dependence

    phase 2 small molecule completed

    2 trials
  38. Propranolol

    BRIGHT MINDS BIOSCIENCES INC.

    Cocaine-Related Disorders

    phase 2 small molecule completed

    1 trial
  39. Prostate alone IMRT

    United Therapeutics Europe Ltd

    Prostate Cancer

    phase 2 other active

    1 trial
  40. Protocol number 8

    The George Institute

    Glioblstoma WHO grade IV

    phase 2 small molecule active

    1 trial
  41. Provisc

    AEON Biopharma

    Steroid Induced Glaucoma

    phase 2 small molecule completed

    1 trial
  42. Provox Vega voice prosthesis 22.5 Fr

    ATOSSA THERAPEUTICS, INC.

    Total Laryngectomy

    phase 2 other completed

    1 trial
  43. Provox voice prosthesis

    ATOSSA THERAPEUTICS, INC.

    Total Laryngectomy

    phase 2 other completed

    1 trial
  44. Psilocybin

    BRIGHT MINDS BIOSCIENCES INC.

    Opioid Use Disorder

    phase 2 small molecule active

    1 trial
  45. Psilocybin

    BRIGHT MINDS BIOSCIENCES INC.

    Healthy

    phase 2 small molecule completed

    1 trial
  46. Psilocybin

    Compass Therapeutics

    Anorexia Nervosa

    phase 2 small molecule completed

    2 trials
  47. Psilocybin

    COGNITION THERAPEUTICS INC

    Treatment Resistant Depression

    phase 2 small molecule completed

    1 trial
  48. Psilocybin

    BRIGHT MINDS BIOSCIENCES INC.

    Tobacco Use Disorder

    phase 2 small molecule active

    1 trial

Frequently asked questions

How many Phase II pipeline programs are in the directory?

7,238 published programs match this development stage in our ClinicalTrials.gov index.

What defines this pipeline stage?

Phase and status reflect ClinicalTrials.gov registry fields at last sync. See our clinical trial phases reference for methodology.