Saturday, July 11, 2026

Intelligence · Clinical pipeline

Phase II Pipeline Programs

Proof-of-concept and dose-finding clinical programs in Phase II development.

Programs 7,238
Sponsors 1,771
Drugs 4,798

Quick answer

NovaPharmaNews tracks 7,238 phase ii pharmaceutical pipeline programs from ClinicalTrials.gov. Proof-of-concept and dose-finding clinical programs in Phase II development.

Top sponsors

Pipeline programs

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  1. Placebo capsules

    BRIGHT MINDS BIOSCIENCES INC.

    Pain Threshold

    phase 2 small molecule completed

    1 trial
  2. Placebo de macitentan 10 mg, MACITENTAN

    Pari Pharma GmbH

    Inoperable Chronic thromboembolic pulmonary hyperTension, Pneumology

    phase 2 small molecule active

    1 trial
  3. Placebo for ABBV-142

    AbbVie Deutschland GmbH & Co. KG

    Idiopathic Pulmonary Fibrosis

    phase 2 small molecule active

    1 trial
  4. Placebo for ACP-204 capsules

    Lacuna Pharma Pty Ltd

    Lewy Body Dementia Psychosis (LBDP)

    phase 2 small molecule active

    1 trial
  5. Placebo for AMG 133, AMG 133

    Amgen

    Type 2 Diabetes Mellitus

    phase 2 small molecule active

    1 trial
  6. Placebo for AMG 451, Rocatinlimab

    Amgen

    Moderate-to-severe Asthma

    phase 2 small molecule active

    1 trial
  7. Placebo for AZD4144, AZD4144

    AstraZeneca AB

    Sepsis-associated acute kidney injury (AKI)

    phase 2 small molecule active

    1 trial
  8. Placebo for AZD5148, AZD5148

    AstraZeneca AB

    Recurrence of Clostridioides difficile Infection

    phase 2 small molecule active

    1 trial
  9. Placebo for GSK5784283.

    GlaxoSmithKline

    Asthma

    phase 2 small molecule active

    1 trial
  10. Placebo for JNJ-95597528, JNJ-95597528

    Janssen-Cilag International N.V.

    Moderate to Severe Atopic Dermatitis

    phase 2 small molecule active

    1 trial
  11. Placebo for KER-012, cibotercept

    Keros Therapeutics

    Pulmonary Arterial Hypertension

    phase 2 small molecule active

    1 trial
  12. Placebo for LAD603, LAD603

    Almirall, S.A.

    Alopecia areata

    phase 2 small molecule active

    1 trial
  13. Placebo for MK-7240, tulisokibart

    Merck Sharp and Dohme

    Radiographic axial spondyloarthritis (as known as ankylosing spondylitis)

    phase 2 small molecule active

    1 trial
  14. Placebo for ML-007C-MA bilayer tablet

    MapLight Therapeutics

    Hallucinations and Delusions Associated with Alzheimer’s Disease Psychosis

    phase 2 small molecule active

    1 trial
  15. Placebo for SPT-300

    Seaport Therapeutics

    Major Depressive Disorder (MDD), with or without Anxious Distress

    phase 2 small molecule active

    1 trial
  16. Placebo for bms-986435-01

    Bristol-Myers Squibb Australia Pty Ltd

    Heart failure with preserved ejection fraction (HFpEF)

    phase 2 small molecule active

    1 trial
  17. Placebo matching BI 764198, BI 764198

    Boehringer Ingelheim

    Proteinuric kidney diseases

    phase 2 small molecule active

    1 trial
  18. Placebo of IPN10200, IPN10200

    Ipsen

    Cervical Dystonia

    phase 2 small molecule active

    1 trial
  19. Placebo of NAL, NACYSTELYN

    Laboratoire HRA Pharma

    Obstructive Sleep Apnea

    phase 2 small molecule active

    1 trial
  20. Placebo oral capsule

    United Therapeutics Europe Ltd

    Osteoarthritis, Knee

    phase 2 small molecule completed

    1 trial
  21. Placebo session 1, Aprepitant session 2

    BRIGHT MINDS BIOSCIENCES INC.

    Cocaine Dependence

    phase 2 small molecule completed

    1 trial
  22. Placebo to AVTX-009, AVTX-009

    Avalo Therapeutics

    Hidradenitis suppurativa (HS)

    phase 2 small molecule active

    1 trial
  23. Placebo to BAY 3401016, BAY 3401016

    Bayer AG

    Alport Syndrome, Chronic kidney disease

    phase 2 small molecule active

    1 trial
  24. Placebo to BI 765423, BI 765423

    Boehringer Ingelheim

    Idiopathic Pulmonary Fibrosis (IPF)

    phase 2 small molecule active

    1 trial
  25. Placebo to MK-6194, MK-6194

    Merck Sharp and Dohme

    Non segmental vitiligo

    phase 2 small molecule active

    1 trial
  26. Placebo to Match GSK3915393 Tablet

    GlaxoSmithKline

    Idiopathic Pulmonary Fibrosis

    phase 2 small molecule active

    1 trial
  27. Placebo to Match GSK3965193 Tablets

    GlaxoSmithKline

    Hepatitis B

    phase 2 small molecule active

    1 trial
  28. Placebo to match ACP-204

    Lacuna Pharma Pty Ltd

    Alzheimer Disease psychosis

    phase 2 small molecule active

    1 trial
  29. Placebo to match IMP Lu AG09222

    H. Lundbeck A/S

    Migraine

    phase 2 small molecule active

    1 trial
  30. Placebo to match IMP TEV-56286, Emrusolmin

    Lacuna Pharma Pty Ltd

    Multiple System Atrophy

    phase 2 small molecule active

    1 trial
  31. Placebo to match LY3540378

    Eli Lilly Co.

    Heart Failure with Preserved Ejection Fraction, Heart Failure

    phase 2 small molecule active

    1 trial
  32. Placebo to match LY3556050

    Eli Lilly Co.

    Diabetic Peripheral Neuropathy

    phase 2 small molecule active

    1 trial
  33. Placebo to match LY3848575

    Eli Lilly Co.

    Neuropathic Pain; Distal Sensory Polyneuropathy

    phase 2 small molecule active

    1 trial
  34. Placebo transplantation

    Chinese Academy of Sciences

    Primary Ovarian Insufficiency

    phase 2 mab active

    1 trial
  35. Placebo, APG777

    Apogee Therapeutics

    Atopic Dermatitis

    phase 2 small molecule active

    1 trial
  36. Placebo, BFB759

    Blue Earth Diagnostics Ireland Ltd

    Hidradenitis Suppurativa

    phase 2 small molecule active

    1 trial
  37. Placebo, GLUCOPHAGE 500 mg tabletki powlekane

    Bial Portela & Companhia S.A.

    idiopathic infertility

    phase 2 small molecule active

    1 trial
  38. Placebos

    BRIGHT MINDS BIOSCIENCES INC.

    Cannabis

    phase 2 small molecule completed

    1 trial
  39. Plasma rich in growth factors

    The George Institute

    Low Reserve Ovarian

    phase 2 small molecule active

    1 trial
  40. Plerixafor

    SANGAMO THERAPEUTICS, INC

    Sickle Cell Disease

    phase 2 mab completed

    1 trial
  41. Plerixafor

    Cardiff Oncology

    Acute Myeloid Leukaemia

    phase 2 small molecule completed

    1 trial
  42. Plerixafor

    The First People's Hospital of Lianyungang

    Relapsed Adult ALL

    phase 2 small molecule active

    1 trial
  43. Pluvicto 1 000 MBq/mL solution for injection/infusion

    Ningbo Cancer Hospital

    Clear Cell Renal Cell Carcinoma (ccRCC)

    phase 2 small molecule active

    1 trial
  44. Pociredir

    Fulcrum Therapeutics

    Sickle Cell Disease

    phase 2 small molecule active

    2 trials
  45. PolyCore

    Lacuna Pharma Pty Ltd

    End-Stage Kidney Disease

    phase 2 small molecule active

    1 trial
  46. Pomalidomide

    Celgene Europe Limited

    Multiple Myeloma

    phase 2 small molecule completed

    1 trial
  47. Ponatinib

    Takeda

    GIST

    phase 2 small molecule completed

    1 trial
  48. Ponatinib

    Cardiff Oncology

    Acute Lymphoblastic Leukemia, Adult

    phase 2 small molecule active

    1 trial

Frequently asked questions

How many Phase II pipeline programs are in the directory?

7,238 published programs match this development stage in our ClinicalTrials.gov index.

What defines this pipeline stage?

Phase and status reflect ClinicalTrials.gov registry fields at last sync. See our clinical trial phases reference for methodology.