Saturday, July 11, 2026
🇺🇸 FDA

Intelligence · Clinical pipeline

Phase II Pipeline Programs

Proof-of-concept and dose-finding clinical programs in Phase II development.

Programs 7,238
Sponsors 1,771
Drugs 4,798

Quick answer

NovaPharmaNews tracks 7,238 phase ii pharmaceutical pipeline programs from ClinicalTrials.gov. Proof-of-concept and dose-finding clinical programs in Phase II development.

Top sponsors

Pipeline programs

Page 100 of 151

  1. PTC857

    PTC THERAPEUTICS, INC.

    Amyotrophic Lateral Sclerosis

    phase 2 small molecule terminated

    1 trial

  2. PTC857-CNS-001-ALS

    PTC THERAPEUTICS, INC.

    Amyotrophic Lateral Sclerosis

    phase 2 small molecule active

    1 trial

  3. PTC923

    PTC THERAPEUTICS, INC.

    BH4 Deficiency

    phase 2 small molecule completed

    1 trial

  4. PTCL S-IDE

    Fondazione Telethon ETS

    Relapsed or Refractory Peripheral T-cell Lymphomas

    phase 2 small molecule active

    1 trial

  5. PTG-100

    Protagonist Therapeutics, Inc

    Ulcerative Colitis

    phase 2 small molecule terminated

    1 trial

  6. PTG-300

    Protagonist Therapeutics, Inc

    β-thalassemia

    phase 2 small molecule completed

    2 trials

  7. PTG-300

    Protagonist Therapeutics, Inc

    Polycythemia Vera

    phase 2 small molecule completed

    2 trials

  8. PTG-300

    Protagonist Therapeutics, Inc

    Hereditary Hemochromatosis

    phase 2 small molecule completed

    1 trial

  9. PTG-CARCIK-CD19

    Fondazione Telethon ETS

    B-Non Hodgkin Lymphoma and Chronic Lymphocytic Leukemia

    phase 2 small molecule active

    1 trial

  10. PTG-CARCIK-CD19

    Fondazione Telethon ETS

    B cell precursor Acute Lymphoblastic Leukemia

    phase 2 small molecule active

    1 trial

  11. PTH

    Blackmores Limited

    Osteoporosis

    phase 2 small molecule completed

    1 trial

  12. PTR-01

    BridgeBio Oncology Therapeutics

    Recessive Dystrophic Epidermolysis Bullosa

    phase 2 small molecule completed

    1 trial

  13. PTT101

    Alphapharm Pty Ltd

    Central nervous system (CNS) lymphoma; recurrent or refractory primary or isolated secondary

    phase 2 small molecule active

    1 trial

  14. PTX-022

    PALVELLA THERAPEUTICS, INC.

    Microcystic Lymphatic Malformation

    phase 2 small molecule completed

    1 trial

  15. PTX-022

    PALVELLA THERAPEUTICS, INC.

    Angiokeratomas

    phase 2 small molecule active

    1 trial

  16. PTX-022

    PALVELLA THERAPEUTICS, INC.

    BCCs in Gorlin Syndrome Patients

    phase 2 small molecule completed

    1 trial

  17. PUL-042 Inhalation Solution

    United Therapeutics Europe Ltd

    COVID-19

    phase 2 small molecule completed

    2 trials

  18. PUMA-ALI-1201

    PUMA BIOTECHNOLOGY, INC.

    Hormone receptor positive (HR+), human epidermal growth factor receptor 2 negative (HER2-) recurrent or metastatic breast cancer (MBC)

    phase 2 small molecule active

    1 trial

  19. PURSUIT

    AstraZeneca AB

    Dyslipidemia Dyslipidemias are alterations to the plasma lipid profile associated often with clinical condition. A common form of dyslipidemia is Hypercholesterolemia due to high level of LDL-cholesterol, which is a major risk factor for Cardiovascular Disease (CVD), such as Ischemic Heart Disease and Ischemic Stroke. CVD is a leading cause of global mortality and a contributor to disability.

    phase 2 small molecule active

    1 trial

  20. PV-10

    PROVECTUS BIOPHARMACEUTICALS, INC.

    Melanoma

    phase 2 small molecule active

    2 trials

  21. PV-10 (10% rose bengal disodium)

    PROVECTUS BIOPHARMACEUTICALS, INC.

    Melanoma

    phase 2 small molecule completed

    1 trial

  22. PVS-10200

    Takeda

    Peripheral Artery Disease

    phase 2 mab completed

    1 trial

  23. PVX 2024-01

    Lacuna Pharma Pty Ltd

    Subjects having local anesthesia for dental procedures.

    phase 2 small molecule active

    1 trial

  24. PYX-201

    Pyxis Oncology

    Advanced Solid Tumors

    phase 2 small molecule active

    1 trial

  25. PYX-201-102

    Pyxis Oncology

    Advanced Solid Tumors

    phase 2 other active

    1 trial

  26. Paclitaxel

    Merck KGaA, Darmstadt, Germany

    Esophageal Squamous Cell Carcinoma

    phase 2 small molecule active

    1 trial

  27. Paclitaxel

    CNS Pharmaceuticals

    Ovarian Cancer

    phase 2 small molecule completed

    1 trial

  28. Paclitaxel

    Jazz Pharmaceuticals Ireland Limited

    Gastroesophageal Adenocarcinoma

    phase 2 small molecule active

    1 trial

  29. Paclitaxel

    Cardiff Oncology

    Carcinosarcoma

    phase 2 small molecule active

    1 trial

  30. Paclitaxel

    ONCOLYTICS BIOTECH INC

    Metastatic Breast Cancer

    phase 2 small molecule completed

    1 trial

  31. Paclitaxel

    PUMA BIOTECHNOLOGY, INC.

    Breast Cancer

    phase 2 small molecule completed

    1 trial

  32. Paclitaxel

    ONCOLYTICS BIOTECH INC

    Breast Cancer Metastatic

    phase 2 small molecule active

    1 trial

  33. Paclitaxel

    Takeda

    Endometrial Neoplasms

    phase 2 small molecule completed

    1 trial

  34. Paclitaxel

    United Therapeutics Europe Ltd

    Clinical Stage III Gastric Cancer AJCC v8

    phase 2 small molecule active

    1 trial

  35. Paclitaxel

    Takeda

    Ovarian Cancer

    phase 2 small molecule completed

    1 trial

  36. Paclitaxel /ml Concentrate for Resectable Locally Advanced Ora…

    Fondazione Telethon ETS

    Resectable Locally Advanced Oral Cavity Squamous Cell Carcinoma

    phase 2 small molecule active

    1 trial

  37. Paclitaxel and TAK-228

    Takeda

    Metastatic Urothelial Cancer

    phase 2 other active

    1 trial

  38. Pacritinib

    MEDA Pharma GmbH & Co. KG

    Patients with myelofibrosis and platelets counts between 50 - 120 x 10e9/L

    phase 2 small molecule active

    1 trial

  39. Pacritinib

    Takeda

    Primary Myelofibrosis

    phase 2 mab terminated

    1 trial

  40. Pacritinib

    Karyopharm Therapeutics Inc

    Myelofibrosis

    phase 2 small molecule active

    1 trial

  41. Palbociclib 125Mg Tab

    United Therapeutics Europe Ltd

    ER+ Breast Cancer

    phase 2 small molecule active

    1 trial

  42. Palifosfamide Tris and Doxorubicin

    Alaunos Therapeutics

    Soft Tissue Sarcoma

    phase 2 small molecule active

    1 trial

  43. Palmidrol

    United Therapeutics Europe Ltd

    Chemotherapy-Induced Peripheral Neuropathy

    phase 2 small molecule active

    1 trial

  44. Paltusotine tablets, Paltusotine tablets

    Lacuna Pharma Pty Ltd

    Acromegaly

    phase 2 small molecule active

    1 trial

  45. Pancreatoduodenectomy

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Pancreatic Cancer

    phase 2 other active

    1 trial

  46. Panitumumab

    Takeda

    Squamous Cell Carcinoma of Head and Neck

    phase 2 small molecule completed

    1 trial

  47. Panitumumab

    BRIGHT MINDS BIOSCIENCES INC.

    Advanced Head and Neck Squamous Cancer

    phase 2 small molecule completed

    1 trial

  48. Panitumumab

    United Therapeutics Europe Ltd

    Metastatic Colon Adenocarcinoma

    phase 2 mab active

    1 trial

Frequently asked questions

How many Phase II pipeline programs are in the directory?

7,238 published programs match this development stage in our ClinicalTrials.gov index.

What defines this pipeline stage?

Phase and status reflect ClinicalTrials.gov registry fields at last sync. See our clinical trial phases reference for methodology.

Drug approvals, clinical trials, M&A, event intelligence, and company updates — weekly.

Customize topics & region
Topics
Region

No spam. Unsubscribe anytime. See our privacy policy.