Tuesday, July 21, 2026

Intelligence · Clinical pipeline

Phase II Pipeline Programs

Proof-of-concept and dose-finding clinical programs in Phase II development.

Programs 135
Sponsors 800
Drugs 4,222

Quick answer

NovaPharmaNews tracks 135 phase ii pharmaceutical pipeline programs from ClinicalTrials.gov. Proof-of-concept and dose-finding clinical programs in Phase II development.

Top sponsors

Pipeline programs

Page 3 of 3
  1. REOLYSIN®

    ONCOLYTICS BIOTECH INC

    Osteosarcoma

    phase 2 mab completed

    1 trial
  2. Riluzole Oral Soluble Film

    Aquestive Therapeutics

    ALS

    phase 2 small molecule terminated

    1 trial
  3. Rimonabant

    BRIGHT MINDS BIOSCIENCES INC.

    Schizophrenia

    phase 2 small molecule terminated

    1 trial
  4. Risperidone

    Indivior Pty Ltd

    Schizophrenia

    phase 2 small molecule completed

    1 trial
  5. SNOXA12C401

    Lacuna Pharma Pty Ltd

    Glioblastoma

    phase 2 small molecule active

    1 trial
  6. Sabin-Based Inactivated Poliomyelitis Vaccine (sIPV)

    Takeda

    Poliomyelitis

    phase 2 mab terminated

    1 trial
  7. Selinexor

    Karyopharm Therapeutics Inc

    Glioblastoma

    phase 2 small molecule terminated

    1 trial
  8. Selinexor

    Karyopharm Therapeutics Inc

    Thymoma

    phase 2 small molecule active

    1 trial
  9. Semaglutide

    United Therapeutics Europe Ltd

    Cardiomyopathy

    phase 2 small molecule active

    1 trial
  10. Sodium Oxybate

    Jazz Pharmaceuticals Ireland Limited

    Schizophrenia

    phase 2 small molecule completed

    1 trial
  11. TD-9855 Group 1

    Theravance Biopharma Ireland Umited

    Fibromyalgia

    phase 2 small molecule completed

    1 trial
  12. TTP435

    vTv Therapeutics

    Obesity

    phase 2 small molecule completed

    1 trial
  13. TYRA-300 0.125 mg/kg

    Tyra Biosciences

    Achondroplasia

    phase 2 small molecule active

    1 trial
  14. Talampanel

    Teva Pharma GmbH

    ALS

    phase 2 small molecule completed

    1 trial
  15. Temozolomide

    PUMA BIOTECHNOLOGY, INC.

    Glioblastoma

    phase 2 small molecule active

    1 trial
  16. Tipifarnib

    Kura Oncology

    HNSCC

    phase 2 small molecule completed

    1 trial
  17. Tirzepatide

    Regeneron UK Limited

    Obesity

    phase 2 small molecule completed

    1 trial
  18. Tislelizumab

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    HNSCC

    phase 2 small molecule active

    1 trial
  19. Tislelizumab combined with chemoradiotherapy

    The First People's Hospital of Lianyungang

    ESCC

    phase 2 small molecule active

    1 trial
  20. Tradipitant

    Vanda Pharmaceuticals Netherlands B.V.

    Obesity

    phase 2 small molecule completed

    1 trial
  21. Triheptanoin

    Ultragenyx UK Limited

    ALS

    phase 2 small molecule completed

    1 trial
  22. Trilaciclib

    The First People's Hospital of Lianyungang

    Osteosarcoma

    phase 2 small molecule active

    1 trial
  23. Umbralisib

    TG THERAPEUTICS, INC.

    Lymphoma

    phase 2 small molecule terminated

    1 trial
  24. Vaccine PvCS N+C+R

    BRIGHT MINDS BIOSCIENCES INC.

    Malaria

    phase 2 mab completed

    1 trial
  25. Xyrem (sodium oxybate) oral solution

    Jazz Pharmaceuticals Ireland Limited

    Fibromyalgia

    phase 2 small molecule completed

    1 trial
  26. ZN-d5

    Zentalis Pharmaceuticals

    Amyloidosis

    phase 2 small molecule completed

    1 trial
  27. aleniglipron or placebo

    Structure Therapeutics

    Obesity

    phase 2 small molecule completed

    1 trial
  28. armodafinil

    Teva Pharma GmbH

    Schizophrenia

    phase 2 small molecule completed

    2 trials
  29. autologous anti-BCMA chimeric antigen receptor T cells

    The First People's Hospital of Lianyungang

    ITP

    phase 2 mab active

    1 trial
  30. certepetide

    LISATA THERAPEUTICS, INC.

    Cholangiocarcinoma

    phase 2 small molecule active

    1 trial
  31. forodesine hydrochloride

    Biocryst

    Lymphoma

    phase 2 small molecule completed

    2 trials
  32. fostamatinib

    RIGEL PHARMACEUTICALS INC

    Lymphoma

    phase 2 small molecule completed

    1 trial
  33. heme arginate

    Ultragenyx UK Limited

    Porphyria

    phase 2 small molecule completed

    3 trials
  34. induction chemotherapy and immunotherapy

    The First People's Hospital of Lianyungang

    ESCC

    phase 2 small molecule completed

    1 trial
  35. levamisole

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Anemia

    phase 2 small molecule active

    1 trial
  36. mutual support group

    Hong Kong Baptist University

    Schizophrenia

    phase 2 other completed

    1 trial
  37. peginesatide

    Takeda

    Anemia

    phase 2 small molecule completed

    5 trials
  38. rituximab

    United Therapeutics Europe Ltd

    Lymphoma

    phase 2 mab completed

    1 trial
  39. vosoritide

    BioMarin Pharmaceutical Australia Pty Ltd

    Achondroplasia

    phase 2 mab active

    1 trial

Frequently asked questions

How many Phase II pipeline programs are in the directory?

135 published programs match this development stage in our ClinicalTrials.gov index.

What defines this pipeline stage?

Phase and status reflect ClinicalTrials.gov registry fields at last sync. See our clinical trial phases reference for methodology.