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Intelligence · Clinical pipeline

Phase I Pipeline Programs

First-in-human and early clinical safety studies in Phase I.

Programs 4,713
Sponsors 1,771
Drugs 4,798

Quick answer

NovaPharmaNews tracks 4,713 phase i pharmaceutical pipeline programs from ClinicalTrials.gov. First-in-human and early clinical safety studies in Phase I.

Top sponsors

Pipeline programs

Page 95 of 99

  1. casdatifan

    Arcus Biosciences

    Clear Cell Renal Cell Carcinoma

    phase 1 small molecule active

    1 trial

  2. cefprozil

    Teva Pharma GmbH

    Healthy

    phase 1 small molecule completed

    1 trial

  3. cemiplimab

    Regeneron UK Limited

    Relapsed/Refractory Aggressive B-Cell Lymphoma

    phase 1 small molecule active

    1 trial

  4. cimetidine (or acyclovir)

    BRIGHT MINDS BIOSCIENCES INC.

    Healthy

    phase 1 small molecule completed

    1 trial

  5. ciprofloxacin

    BRIGHT MINDS BIOSCIENCES INC.

    Healthy

    phase 1 small molecule completed

    1 trial

  6. cisplatin oxaliplatin tegafur

    The First People's Hospital of Lianyungang

    Gastric Cancer

    phase 1 small molecule active

    1 trial

  7. cocaine

    BRIGHT MINDS BIOSCIENCES INC.

    Cocaine Use

    phase 1 small molecule completed

    1 trial

  8. cocaine hydrochloride

    BRIGHT MINDS BIOSCIENCES INC.

    Cocaine Dependence

    phase 1 small molecule completed

    1 trial

  9. colchicine

    Ultragenyx UK Limited

    Cirrhosis

    phase 1 small molecule active

    1 trial

  10. conivaptan hydrochloride

    CUMBERLAND PHARMACEUTICALS INC

    Kidney Diseases

    phase 1 small molecule completed

    1 trial

  11. conivaptan hydrochloride

    CUMBERLAND PHARMACEUTICALS INC

    Liver Disease

    phase 1 small molecule completed

    2 trials

  12. cyclophosphamide

    Evidence Based Cataract Study Group

    Malignant Pleural Mesothelioma (MPM)

    phase 1 small molecule active

    1 trial

  13. cyclophosphamide

    Ultragenyx UK Limited

    Multiple Sclerosis

    phase 1 small molecule completed

    1 trial

  14. d-amphetamine

    BRIGHT MINDS BIOSCIENCES INC.

    Cocaine-Related Disorders

    phase 1 small molecule completed

    1 trial

  15. d-amphetamine

    BRIGHT MINDS BIOSCIENCES INC.

    Cocaine Dependence

    phase 1 small molecule completed

    1 trial

  16. d-amphetamine

    BRIGHT MINDS BIOSCIENCES INC.

    Cocaine Use Disorder

    phase 1 small molecule active

    1 trial

  17. d-cycloserine

    United Therapeutics Europe Ltd

    Chronic Obstructive Pulmonary Disease

    phase 1 small molecule active

    1 trial

  18. dMAb AZD5396

    INOVIO PHARMACEUTICALS, INC.

    Healthy Volunteers

    phase 1 other completed

    1 trial

  19. danoprevir

    Hoffmann-La Roche

    Healthy Volunteer

    phase 1 small molecule completed

    1 trial

  20. darinaparsin

    Alaunos Therapeutics

    Lymphoma

    phase 1 small molecule terminated

    1 trial

  21. darinaparsin

    Alaunos Therapeutics

    Advanced Solid Tumors

    phase 1 small molecule completed

    1 trial

  22. decitabine

    Karyopharm Therapeutics Inc

    Acute Myeloid Leukemia

    phase 1 small molecule completed

    1 trial

  23. delta 9 tetrahydrocannabinol

    BRIGHT MINDS BIOSCIENCES INC.

    COMT Gene Polymorphism

    phase 1 small molecule completed

    1 trial

  24. dendritic cell

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Recurrent Ovarian Cancer

    phase 1 mab active

    1 trial

  25. dexlansoprazole injection

    The First People's Hospital of Lianyungang

    Safety Issues

    phase 1 small molecule completed

    1 trial

  26. domestic polysaccharide superparamagnetic iron oxide nanoparticle

    The First People's Hospital of Lianyungang

    Chronic Kidney Diseases

    phase 1 small molecule completed

    1 trial

  27. drug condition

    BRIGHT MINDS BIOSCIENCES INC.

    Cannabis

    phase 1 small molecule completed

    1 trial

  28. eASC

    Takeda

    Localized Adverse Reaction to Administration of Drug

    phase 1 gene therapy completed

    1 trial

  29. engineered autologous T cells

    United Therapeutics Europe Ltd

    Prostate Cancer

    phase 1 mab active

    1 trial

  30. entinostat

    Syndax Pharmaceuticals

    Lung Cancer

    phase 1 small molecule completed

    1 trial

  31. eszopiclone

    BRIGHT MINDS BIOSCIENCES INC.

    Marijuana Dependence

    phase 1 small molecule completed

    1 trial

  32. etrumadenant

    Arcus Biosciences

    GastroEsophageal Cancer

    phase 1 small molecule completed

    1 trial

  33. evorpacept

    ALX ONCOLOGY HOLDINGS INC

    Acute Myeloid Leukemia

    phase 1 small molecule terminated

    1 trial

  34. evorpacept

    ALX ONCOLOGY HOLDINGS INC

    Higher Risk Myelodysplastic Syndromes

    phase 1 small molecule terminated

    1 trial

  35. fRPE cells

    The First People's Hospital of Lianyungang

    Age Related Macular Degeneration

    phase 1 small molecule active

    1 trial

  36. filgrastim

    Ultragenyx UK Limited

    Fanconi's Anemia

    phase 1 small molecule active

    1 trial

  37. firibastat

    Quantum Biopharma

    Healthy Volunteers

    phase 1 small molecule completed

    1 trial

  38. forodesine hydrochloride

    Biocryst

    Cancer

    phase 1 small molecule completed

    1 trial

  39. galidesivir

    Biocryst

    Marburg Virus Disease

    phase 1 small molecule completed

    1 trial

  40. gene therapy

    Ultragenyx UK Limited

    Familial Hypercholesterolemia

    phase 1 other completed

    1 trial

  41. givosiran (ALN-AS1)

    Alnylam Netherlands B.V.

    Acute Intermittent Porphyria

    phase 1 small molecule completed

    1 trial

  42. hCD19.IL15.CAR-iNKT

    The First People's Hospital of Lianyungang

    Acute Lymphoblastic Leukemia

    phase 1 small molecule active

    1 trial

  43. hGH-ViaDerm™ System (hGH or somatropin)

    Teva Pharma GmbH

    Growth Hormone Deficiency

    phase 1 small molecule completed

    1 trial

  44. hUCB

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Acute Ischemic Stroke

    phase 1 other completed

    1 trial

  45. hVEGF-A

    SANGAMO THERAPEUTICS, INC

    Diabetic Neuropathy

    phase 1 gene therapy completed

    1 trial

  46. haploid allogeneic NK cell therapy

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Acute Myeloid Leukemia

    phase 1 mab active

    1 trial

  47. high-dose Group ACYW135X Meningococcal Conjugate Vaccine

    Sinovac Research and Development Co.,

    Meningococcal Meningitis

    phase 1 mab active

    1 trial

  48. high-fat diet group（AD16 20mg）

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Alzheimer Disease

    phase 1 other completed

    1 trial

Frequently asked questions

How many Phase I pipeline programs are in the directory?

4,713 published programs match this development stage in our ClinicalTrials.gov index.

What defines this pipeline stage?

Phase and status reflect ClinicalTrials.gov registry fields at last sync. See our clinical trial phases reference for methodology.

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