Autoimmune & immunology · Phase I Pipeline

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Autoimmune & immunology Phase I programs: NovaPharmaNews indexes 167 matching clinical development programs from ClinicalTrials.gov with sponsor, modality, and NCT cross-links.

Top sponsors

Pipeline programs

Page 1 of 4

1% icotinib hydrochloride cream

Betta Pharmaceuticals Co.,

Psoriasis

phase 1 small molecule completed

1 trial
1474-0002

Boehringer Ingelheim

Plaque psoriasis

phase 1 other active

1 trial
221458

GlaxoSmithKline

Systemic Lupus Erythematosus

phase 1 other active

1 trial
221615

GlaxoSmithKline

Systemic Lupus Erythematosus

phase 1 other active

1 trial
300134

GlaxoSmithKline

Systemic Lupus Erythematosus

phase 1 other active

1 trial
50 mg LX3305 QD

LEXICON PHARMACEUTICALS, INC.

Rheumatoid Arthritis

phase 1 small molecule completed

1 trial
608

Sunshine Guojian Pharmaceutical (Shanghai) Co.,

Moderate to Severe Plaque Psoriasis

phase 1 small molecule active

1 trial
88545223PSO1001

Janssen-Cilag International N.V.

Psoriasis

phase 1 other active

1 trial
A clinical study of MK-2420 in healthy men (MK-2420-003)

Merck Sharp and Dohme

Rheumatoid arthritis

phase 1 other active

1 trial
A clinical study of MK-2420 in healthy people (MK-2420-002)

Merck Sharp and Dohme

Rheumatoid arthritis

phase 1 other active

1 trial
A study to assess the effect of single and re... for Plaque Psoriasis

Janssen-Cilag International N.V.

Plaque Psoriasis

phase 1 other active

1 trial
A148_01PK2408

Lacuna Pharma Pty Ltd

Active psoriatic arthritis, Moderately to severely active Crohn’s disease, Moderate-to-severe plaque psoriasis, Moderately to severely active ulcerative colitis

phase 1 other active

1 trial
AB-101

Artiva Biotherapeutics

Lupus Nephritis - WHO Class III

phase 1 small molecule active

1 trial
AB-101

Artiva Biotherapeutics

Rheumatoid Arthritis

phase 1 small molecule active

1 trial
ABI-M201

ASSEMBLY BIOSCIENCES, INC.

Ulcerative Colitis Chronic Mild

phase 1 small molecule terminated

1 trial
AFN50 injection

The First People's Hospital of Lianyungang

Autoimmune Diseases

phase 1 mab active

1 trial
AGMB129-01-CL-109

Agomab Therapeutics NV

Fibrostenotic Crohn’s disease

phase 1 other active

1 trial
ALLO-329

Allogene Therapeutics

Systemic Lupus Erythematosus (With and Without Nephritis)

phase 1 gene therapy active

1 trial
AN OPEN-LABEL for Intramuscular administration of…

Lacuna Pharma Pty Ltd

Intramuscular administration of triamcinolone acetonide Lisapharma (Injectable suspension of triamcinolone acetonide) is indicated for systemic corticosteroid therapy in morbid conditions such as allergic syndrome (to control severe or debilitating conditions not treatable in a conventional way), dermatoses, generalized rheumatoid arthritis and other connective tissue diseases.

phase 1 other active

1 trial
APVO210

Aptevo Therapeutics

Psoriasis

phase 1 mab terminated

1 trial
ARQ-151- cream 0.3%

Arcutis Biotherapeutics

Plaque Psoriasis

phase 1 small molecule completed

1 trial
ARQ-154 Foam 0.3%

Arcutis Biotherapeutics

Psoriasis

phase 1 small molecule completed

1 trial
ART-I02

BRIGHT MINDS BIOSCIENCES INC.

Arthritis, Rheumatoid

phase 1 gene therapy active

1 trial
ATA3219

Evidence Based Cataract Study Group

Lupus Nephritis

phase 1 small molecule terminated

1 trial
ATHENA CAR-T

The First People's Hospital of Lianyungang

Lupus Erythematosus, Systemic

phase 1 mab active

1 trial
AUTO1-SL1

Autolus GmbH

Severe, Refractory Systemic Lupus Erythematosus

phase 1 other active

1 trial
Allogeneic CD19/BCMA-targeted CAR-γδT cell injection

Xiyuan Hospital of China Academy of Chinese Medical Sciences

Refractory/Relapsed Systemic Lupus Erythematosus

phase 1 mab active

1 trial
An open-label for inteneded for treatment of - ac…

Lacuna Pharma Pty Ltd

inteneded for treatment of - active rheumatoid arthritis in adult patients, - polyarthritic forms of severe, active juvenile idiopathic arthritis, when the response to nonsteroidal anti-inflammatory drugs has been inadequate, - severe recalcitrant disabling psoriasis which is not adequately responsive to other forms of therapy and severe psoriatic arthritis in adult patients, - mild-to-moderate Crohn’s disease, either alone or in combination with corticosteroids, in adult patients refractory or intolerant to thiopurines.

phase 1 other active

1 trial
Anti-Macrophage Migration Inhibitory Factor (Anti-MIF) Antibody

Takeda

Systemic Lupus Erythematosus

phase 1 small molecule terminated

1 trial
Atorvastatin

Lakefront Biotherapeutics NV

Rheumatoid Arthritis

phase 1 small molecule completed

1 trial
Azercabtagene zapreleucel (azer-cel)

TG THERAPEUTICS, INC.

B-cell Mediated Autoimmune Disorders

phase 1 small molecule active

1 trial
BCMA/CD70 CAR-T cells

Chongqing Precision Biotech Co., Ltd

Systemic Lupus Erythematosus

phase 1 mab active

1 trial
BMS-986202

Bristol-Myers Squibb

Psoriasis

phase 1 small molecule completed

1 trial
C6341001

Pfizer Australia Pty Ltd

Rheumatoid arthritis and Systemic Lupus Erythematosus

phase 1 other active

1 trial
CA061-1001

Celgene Europe Limited

Systemic Sclerosis, Rheumatoid Arthritis (RA), Idiopathic Inflammatory Myopathy, Systemic Lupus Erythematosus (SLE)

phase 1 other active

1 trial
CA061-1006

Celgene Europe Limited

Myasthenia gravis (MG), Progressive Multiple Sclerosis (PMS), Relapsing Multiple Sclerosis (RMS)

phase 1 other active

1 trial
CAIN457E22101

Novartis Pharmaceuticals

Polymyalgia rheumatica (PMR), Giant cell arteritis (GCA)

phase 1 other active

1 trial
CB-010

Caribou Biosciences

Systemic Lupus Erythematosus

phase 1 small molecule terminated

1 trial
CBP-307

S.L

Autoimmune Diseases

phase 1 small molecule completed

2 trials
CBP-307

Connect Biopharm

Autoimmune Diseases

phase 1 small molecule completed

1 trial
CD19 CAR-T cells

Chongqing Precision Biotech Co., Ltd

Systemic Lupus Erythematosus

phase 1 mab active

1 trial
CD19 targeted CAR-T cells

Chongqing Precision Biotech Co., Ltd

SLE (Systemic Lupus)

phase 1 mab active

1 trial
CD19/BCMA in vivo CAR-T

Xiyuan Hospital of China Academy of Chinese Medical Sciences

Autoimmune Diseases

phase 1 small molecule active

1 trial
CLN-978

Cullinan Therapeutics

Rheumatoid Arthritis (RA

phase 1 small molecule active

1 trial
CLN-978-RA-101

Cullinan Therapeutics

Treatment-Refractory Rheumatoid Arthritis

phase 1 other active

1 trial
CLN-978-SL-101

Cullinan Therapeutics

Systemic Lupus Erythematosus

phase 1 other active

1 trial
CNCT19 CAR-T cell therapy

Xiyuan Hospital of China Academy of Chinese Medical Sciences

Autoimmune Hemolytic Anemia

phase 1 mab active

1 trial
CNCT19 cell injection

Juventas Cell Therapy

Neurological Autoimmune Diseases

phase 1 mab active

1 trial

Frequently asked questions

How many autoimmune & immunology Phase I programs exist?

167 programs match both the therapeutic area and stage filters in our published index.

Quick answer

Top sponsors

Pipeline programs

1% icotinib hydrochloride cream

1474-0002

221458

221615

300134

50 mg LX3305 QD

608

88545223PSO1001

A clinical study of MK-2420 in healthy men (MK-2420-003)

A clinical study of MK-2420 in healthy people (MK-2420-002)

A study to assess the effect of single and re... for Plaque Psoriasis

A148_01PK2408

AB-101

AB-101

ABI-M201

AFN50 injection

AGMB129-01-CL-109

ALLO-329

AN OPEN-LABEL for Intramuscular administration of…

APVO210

ARQ-151- cream 0.3%

ARQ-154 Foam 0.3%

ART-I02

ATA3219

ATHENA CAR-T

AUTO1-SL1

Allogeneic CD19/BCMA-targeted CAR-γδT cell injection

An open-label for inteneded for treatment of - ac…

Anti-Macrophage Migration Inhibitory Factor (Anti-MIF) Antibody

Atorvastatin

Azercabtagene zapreleucel (azer-cel)

BCMA/CD70 CAR-T cells

BMS-986202

C6341001

CA061-1001

CA061-1006

CAIN457E22101

CB-010

CBP-307

CBP-307

CD19 CAR-T cells

CD19 targeted CAR-T cells

CD19/BCMA in vivo CAR-T

CLN-978

CLN-978-RA-101

CLN-978-SL-101

CNCT19 CAR-T cell therapy

CNCT19 cell injection

Frequently asked questions

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