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Intelligence · Clinical Pipeline

Phase I Pipeline Programs

First-in-human and early clinical safety studies in Phase I.

Programs
4,713

Quick answer

NovaPharmaNews tracks 4,713 phase i pharmaceutical pipeline programs from ClinicalTrials.gov. First-in-human and early clinical safety studies in Phase I.

Top sponsors

Page 67 of 99

  1. PRT12396

    Prelude Therapeutics Inc

    Polycythemia Vera (PV)

    phase 1 small molecule active

    1 trial

  2. PRT1419

    Prelude Therapeutics Inc

    Multiple Myeloma

    phase 1 small molecule completed

    1 trial

  3. PRT1419

    Prelude Therapeutics Inc

    Sarcoma

    phase 1 small molecule completed

    1 trial

  4. PRT1419

    Prelude Therapeutics Inc

    Acute Myeloid Leukemia

    phase 1 small molecule terminated

    1 trial

  5. PRT2527

    Prelude Therapeutics Inc

    Aggressive B-Cell Non-Hodgkin's Lymphoma (NHL)

    phase 1 small molecule completed

    1 trial

  6. PRT2527

    Prelude Therapeutics Inc

    Sarcoma

    phase 1 small molecule completed

    1 trial

  7. PRT3645

    Prelude Therapeutics Inc

    Breast Cancer

    phase 1 small molecule completed

    1 trial

  8. PRT543

    Prelude Therapeutics Inc

    Relapsed/Refractory Advanced Solid Tumors

    phase 1 small molecule completed

    1 trial

  9. PRT7732

    Prelude Therapeutics Inc

    Advanced Solid Tumor

    phase 1 small molecule terminated

    1 trial

  10. PRT811

    Prelude Therapeutics Inc

    Advanced Solid Tumor

    phase 1 small molecule completed

    1 trial

  11. PRV-002

    Odyssey Therapeutics

    Traumatic Brain Injury (TBI)

    phase 1 small molecule completed

    1 trial

  12. PRX-105

    Protalix BioTherapeutics

    Organophosphate Exposure

    phase 1 small molecule completed

    1 trial

  13. PRX-P4-003, (-)-FCF

    Praxis Precision Medicines

    Healthy Volunteers

    phase 1 small molecule completed

    1 trial

  14. PSA/IL-2/GM-CSF

    United Therapeutics Europe Ltd

    Prostate Cancer

    phase 1 mab active

    1 trial

  15. PTC299

    PTC THERAPEUTICS, INC.

    Leukemia, Myeloid, Acute

    phase 1 small molecule terminated

    1 trial

  16. PTC299

    PTC THERAPEUTICS, INC.

    Metastatic Breast Cancer

    phase 1 small molecule completed

    1 trial

  17. PTC299

    PTC THERAPEUTICS, INC.

    Advanced Cancer

    phase 1 small molecule terminated

    1 trial

  18. PTC596

    PTC THERAPEUTICS, INC.

    High Grade Glioma

    phase 1 small molecule active

    1 trial

  19. PTC596

    PTC THERAPEUTICS, INC.

    Cancer

    phase 1 small molecule completed

    1 trial

  20. PTG-100

    Protagonist Therapeutics, Inc

    Celiac Disease

    phase 1 small molecule completed

    1 trial

  21. PTG-300

    Protagonist Therapeutics, Inc

    Healthy Volunteers

    phase 1 small molecule completed

    1 trial

  22. PTOC1

    Chongqing Precision Biotech Co., Ltd

    Systemic Lupus Erythematosus

    phase 1 mab active

    1 trial

  23. PV-10 (10% rose bengal disodium)

    PROVECTUS BIOPHARMACEUTICALS, INC.

    Cancer Metastatic to the Liver

    phase 1 small molecule active

    1 trial

  24. PV-10 (rose bengal disodium 10%)

    PROVECTUS BIOPHARMACEUTICALS, INC.

    Breast Cancer

    phase 1 small molecule completed

    1 trial

  25. PV-10 (rose bengal disodium, 10%)

    PROVECTUS BIOPHARMACEUTICALS, INC.

    Melanoma

    phase 1 small molecule completed

    1 trial

  26. PVSRIPO

    United Therapeutics Europe Ltd

    Invasive Breast Cancer

    phase 1 mab completed

    1 trial

  27. PYX-106

    Pyxis Oncology

    Solid Tumor

    phase 1 small molecule active

    1 trial

  28. PYX-201

    Pyxis Oncology

    Solid Tumor

    phase 1 small molecule active

    1 trial

  29. Pacing Lead

    Rhythm Pharmaceuticals Netherlands B.V.

    Heart Failure

    phase 1 other completed

    1 trial

  30. Paclitaxel

    Jazz Pharmaceuticals Ireland Limited

    Ovarian Cancer

    phase 1 small molecule active

    1 trial

  31. Paclitaxel

    Hospital Authority, Hong Kong

    Ovarian Cancer

    phase 1 small molecule active

    1 trial

  32. Palazestrant

    Olema Pharmaceuticals

    Metastatic Breast Cancer

    phase 1 small molecule active

    1 trial

  33. Palbociclib + Taselisib / Pictilisib

    United Therapeutics Europe Ltd

    Advanced Solid Tumours

    phase 1 small molecule completed

    1 trial

  34. Panobinostat (LBH589), Carboplatin and Paclitaxel

    BRIGHT MINDS BIOSCIENCES INC.

    Advanced Solid Tumors

    phase 1 small molecule active

    1 trial

  35. Pantoprazole Sodium 40 mg delayed-release tablets

    Teva Pharma GmbH

    Healthy

    phase 1 small molecule completed

    2 trials

  36. Paracetamol 1000mg Tablets, Diphenhydramin-Hevert Injektionslösung, Diphenhydramine Hydrochloride Tablets 25 mg, LYNOZYFIC 200 mg concentrate for solution for infusion, LYNOZYFIC 5 mg concentrate for solution for infusion, Dexamethasone 3.3 mg/ml solution for injection/infusion, REGN17372

    Lacuna Pharma Pty Ltd

    Relapsed/Refractory Multiple Myeloma

    phase 1 small molecule active

    1 trial

  37. Parotid Gland

    BRIGHT MINDS BIOSCIENCES INC.

    Cocaine-Related Disorders

    phase 1 other completed

    1 trial

  38. Paroxetine HCl

    Teva Pharma GmbH

    Healthy

    phase 1 small molecule completed

    2 trials

  39. Part 1

    Harmony Biosciences Holdings

    Drug Interaction

    phase 1 small molecule completed

    1 trial

  40. Part 1 TPST-1120

    Tempest Therapeutics

    Hepatocellular Carcinoma

    phase 1 small molecule completed

    1 trial

  41. Part 1: Cream

    BRIGHT MINDS BIOSCIENCES INC.

    Systemic Exposure to Sunscreen Ingredients

    phase 1 small molecule completed

    1 trial

  42. Part A: Dose Escalation of Cantrixil

    KAZIA THERAPEUTICS LTD

    Ovarian Neoplasms

    phase 1 small molecule completed

    1 trial

  43. Pazopanib

    GlaxoSmithKline

    Neoplasms, Colorectal

    phase 1 small molecule completed

    1 trial

  44. PegInterferon

    Vertex Pharmaceuticals (Australia) Pty.

    Chronic Hepatitis C

    phase 1 small molecule completed

    1 trial

  45. Pegfilgrastim

    Biotech Pharmaceutical Co.,

    Breast Cancer

    phase 1 small molecule completed

    1 trial

  46. Peginterferon lambda

    Biotech Pharmaceutical Co.,

    Hepatitis C

    phase 1 mab completed

    1 trial

  47. Pegylated Recombinant Candida Utilis Uricase for Injection

    Sunshine Guojian Pharmaceutical (Shanghai) Co.,

    Gout

    phase 1 small molecule active

    1 trial

  48. Pelareorep

    ONCOLYTICS BIOTECH INC

    Breast Cancer

    phase 1 mab terminated

    1 trial

Frequently asked questions

How many Phase I pipeline programs are in the directory?

4,713 published programs match this development stage in our ClinicalTrials.gov index.

What defines this pipeline stage?

Phase and status reflect ClinicalTrials.gov registry fields at last sync. See our clinical trial phases reference for methodology.

Data attribution: Data sources · All pipeline programs

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