Wednesday, June 10, 2026

Intelligence · Patents

Patents expiring in 2044

Annual patent cliff calendar for 2044 — US pharmaceutical patents by expiration date.

Patents
1,766

Quick answer

1,766 indexed pharmaceutical patents have expiration dates in 2044. Browse by soonest expiry with links to assignee companies and related drugs.

  1. US 11999773

    Anti-BCMA chimeric antigen receptors

    Cartesian Therapeutics, Inc. · Granted Tue Jun 04 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 30 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  2. IT 202200024948

    Composti attivatori dei canali potassio KV7.2/KV7.3

    ANGELINI PHARMA S P A [IT] · Granted Wed Jun 05 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Tue May 31 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  3. IT 202200024963

    Composti attivatori dei canali potassio Kv7.2/Kv7.3

    ANGELINI PHARMA S P A [IT] · Granted Wed Jun 05 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Tue May 31 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  4. US 2024180883

    TREATMENT OF MIGRAINE

    ALLERGAN PHARMACEUTICALS INT LTD [IE] · Granted Thu Jun 06 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Wed Jun 01 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  5. US 12005220

    Microneedle patch for immunostimulatory drug delivery

    Veradermics Incorporated · Granted Tue Jun 11 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 06 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  6. US 12006517

    Method for purification of bacteriophage particles

    Adaptive Phage Therapeutics, Inc. · Granted Tue Jun 11 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 06 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  7. US 12006522

    Polynucleotides encoding engineered meganucleases having specificity for recognition sequences in the dystrophin gene

    Precision BioSciences, Inc. · Granted Tue Jun 11 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 06 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  8. US 12006365

    Human anti-semaphorin 4D antibody

    VACCINEX, INC. · Granted Tue Jun 11 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 06 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  9. US 12006516

    Differentiation of pancreatic endocrine cells

    Vertex Pharmaceuticals Incorporated · Granted Tue Jun 11 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 06 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  10. US 12006329

    Protein degraders and uses thereof

    Kymera Therapeutics, Inc. · Granted Tue Jun 11 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 06 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  11. US 12006364

    Anti-CD100 antibodies and methods for using the same

    VACCINEX, INC. · Granted Tue Jun 11 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 06 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  12. US 12006363

    Anti-tetraspanin 33 agents and compositions and methods for making and using the same

    BioLegend, Inc. · Granted Tue Jun 11 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 06 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  13. US 12006355

    Nanobodies against cystic fibrosis transmembrane conductance regulator (CFTR) inhibitory factor (Cif)

    The Regents of the University of California · Granted Tue Jun 11 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 06 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  14. US 12006321

    Substituted pyrazolo[1,5-a]pyrimidines as apelin receptor agonists

    SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE · Granted Tue Jun 11 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 06 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  15. US 12006294

    Therapeutic compounds

    Regents of the University of Minnesota · Granted Tue Jun 11 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 06 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  16. US 12006298

    Polymorphic compounds and uses thereof

    Aldeyra Therapeutics, Inc. · Granted Tue Jun 11 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 06 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  17. US 12005115

    Epstein-barr virus vaccines

    The United States of America as Represented by the Secretary of the Department of Health and Human Services · Granted Tue Jun 11 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 06 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  18. US 12005123

    Conjugate of isotretinoin and peptide

    CAREGEN CO., LTD. · Granted Tue Jun 11 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 06 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  19. US 12005126

    Compositions for oral administration of pentosan polysulfate in form of nanoparticles with improved intestinal absorption

    ALMIRA PHARMA SRL · Granted Tue Jun 11 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 06 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  20. US 12005074

    Extrahepatic delivery

    Alnylam Pharmaceuticals, Inc. · Granted Tue Jun 11 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 06 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  21. US 12005066

    Cobinamide compounds as a cyanide, sulfide, or methane-thiol antidote

    The Regents of the University of California · Granted Tue Jun 11 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 06 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  22. US 12005081

    Chimeric receptors and methods of use thereof

    Senti Biosciences, Inc. · Granted Tue Jun 11 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 06 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  23. US 12005052

    Topical roflumilast formulation having improved delivery and plasma half-life

    ARCUTIS BIOTHERAPEUTICS, INC. · Granted Tue Jun 11 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 06 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  24. US 12005060

    Ophthalmic formulations of methotrexate

    Aldeyra Therapeutics, Inc. · Granted Tue Jun 11 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 06 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  25. US 12005055

    Methods for shrinking pituitary tumors

    Corcept Therapeutics Incorporated · Granted Tue Jun 11 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 06 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  26. US 12005127

    DNA-PK inhibitors

    Vertex Pharmaceuticals Incorporated · Granted Tue Jun 11 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 06 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  27. US 12005080

    Method for promoting proliferation of immune cells

    Oricell Therapeutics Co., Ltd. · Granted Tue Jun 11 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 06 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  28. US 12005124

    Muscle targeting complexes and uses thereof for treating dystrophinopathies

    Dyne Therapeutics, Inc. · Granted Tue Jun 11 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 06 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  29. US 12004819

    System and method of performing treatment along a lumen network

    Covidien LP · Granted Tue Jun 11 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 06 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  30. US 12006340

    Nucleotide hemi-sulfate salt for the treatment of hepatitis c virus

    Atea Pharmaceuticals, Inc. · Granted Tue Jun 11 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 06 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  31. US 12006348

    T-cell modulatory multimeric polypeptide with conjugation sites and methods of use thereof

    Cue Biopharma, Inc. · Granted Tue Jun 11 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 06 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  32. US 12006341

    Methods of detection and removal of rhabdoviruses from cell lines

    Takeda Vaccines, Inc. · Granted Tue Jun 11 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 06 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  33. US 12005061

    Ophthalmic formulations of methotrexate

    Aldeyra Therapeutics, Inc. · Granted Tue Jun 11 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 06 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  34. US 12005069

    Bortezomib compositions

    MAIA PHARMACEUTICALS, INC. · Granted Tue Jun 11 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 06 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  35. US 12005054

    Piperidinyl-3-(aryloxy)propanamides and propanoates

    Takeda Pharmaceutical Company Limited · Granted Tue Jun 11 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 06 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  36. US 12005086

    Microbiome related immunotherapies

    Finch Therapeutics Holdings LLC · Granted Tue Jun 11 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 06 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  37. US 12005051

    Topical roflumilast formulation having improved delivery and plasma half life

    ARCUTIS BIOTHERAPEUTICS, INC. · Granted Tue Jun 11 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 06 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  38. US 12005118

    Pharmaceutical compositions comprising meloxicam

    AXSOME THERAPEUTICS, INC. · Granted Tue Jun 11 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 06 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  39. US 12005036

    Methods of administering solriamfetol to lactating women

    AXSOME MALTA LTD. · Granted Tue Jun 11 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 06 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  40. US 12005139

    Ophthalmic formulations and related methods

    ETERNATEAR, INC. · Granted Tue Jun 11 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 06 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  41. US 12005194

    Configurable oxygen concentrator and related method

    SEPARATION DESIGN GROUP LLC · Granted Tue Jun 11 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 06 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  42. CA 3256311

    MÉTHODES D'AMÉLIORATION DE LA SANTÉ OSSEUSE AU MOYEN DE PRODUITS ENRICHIS EN EXOSOMES DE LAIT BOVIN ET DE VITAMINE K2

    ABBOTT LAB [US] · Granted Thu Jun 13 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Wed Jun 08 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  43. US 12012459

    OX40-binding polypeptides and uses thereof

    Inhibrx, Inc. · Granted Tue Jun 18 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 13 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  44. US 12011390

    Lacrimal drug delivery device

    The Regents of the University of Colorado, a Body Corporate · Granted Tue Jun 18 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 13 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  45. US 12012384

    Dextrorphan prodrugs and processes for making and using them

    Zevra Therapeutics, Inc. · Granted Tue Jun 18 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 13 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  46. US 12012468

    Cyclic polypeptides for PCSK9 inhibition

    RA PHARMACEUTICALS, INC. · Granted Tue Jun 18 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 13 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  47. US 12012445

    Anti-VEGF protein compositions and methods for producing the same

    REGENERON PHARMACEUTICALS, INC. · Granted Tue Jun 18 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 13 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  48. US 12013406

    Methods of detecting anti-folic acid antibodies and uses thereof

    The Board of Regents of the University of Texas System · Granted Tue Jun 18 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 13 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

Frequently asked questions

How many pharma patents expire in 2044?

1,766 published patents in our USPTO index have expiration dates falling in calendar year 2044.