Wednesday, June 10, 2026

Intelligence · Patents

Patents expiring in 2044

Annual patent cliff calendar for 2044 — US pharmaceutical patents by expiration date.

Patents
1,766

Quick answer

1,766 indexed pharmaceutical patents have expiration dates in 2044. Browse by soonest expiry with links to assignee companies and related drugs.

  1. US 11992528

    Compositions and methods for conjugating activatable antibodies

    CytomX Therapeutics, Inc. · Granted Tue May 28 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 23 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  2. US 11993644

    Antigen binding molecules targeting SARS-CoV-2

    Generate Biomedicines, Inc. · Granted Tue May 28 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 23 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  3. US 11993658

    Anti-BCMA antibodies and treatment methods

    Sutro Biopharma, Inc. · Granted Tue May 28 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 23 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  4. US 11993603

    Preparation for 6-amino-1H-pyrazolo[3,4-d]pyrimidine-based JAK kinase inhibitor and application thereof

    CHINA PHARMACEUTICAL UNIVERSITY · Granted Tue May 28 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 23 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  5. US 11993580

    Methods of treating neurological disorders

    Neumora Therapeutics, Inc. · Granted Tue May 28 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 23 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  6. US 11993638

    GM-CSF mimetics and methods of making and using same

    The Regents of the University of Colorado, a Body Corporate · Granted Tue May 28 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 23 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  7. US 11993600

    Saturated spirocyclics as antiviral agents

    Enanta Pharmaceuticals, Inc. · Granted Tue May 28 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 23 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  8. US 11992531

    C3-carbon linked glutarimide degronimers for target protein degradation

    C4 THERAPEUTICS, INC. · Granted Tue May 28 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 23 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  9. US 11992530

    Therapeutic uses for sodium thiosulfate and formulations

    Fennec Pharn ceuticals Inc. · Granted Tue May 28 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 23 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  10. US 11993569

    3-amino-4-halocyclopentene carboxylic acids as inactivators of aminotransferases

    Northwestern University · Granted Tue May 28 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 23 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  11. US 11993570

    Cationic lipids

    Takeda Pharmaceutical Company Limited · Granted Tue May 28 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 23 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  12. US 11992514

    Ready-to-use bivalirudin compositions

    MAIA PHARMACEUTICALS, INC. · Granted Tue May 28 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 23 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  13. US 11992523

    Method for producing chikungunya virus (CHIKV) virus-like particles comprising the C, E2, and E1 structural proteins

    The United States of America, as represented by the Secretary, Department of Health and Human Services · Granted Tue May 28 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 23 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  14. US 11992519

    Chimeric antigen receptor (CAR) that targets chemokine receptor CCR4 and its use

    The United States of America, as represented by the Secretary, Department of Health and Human Services · Granted Tue May 28 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 23 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  15. AU 2022390453

    NOVEL HETEROARYL-UREA COMPOUNDS AS KV7.2 INHIBITORS

    ANGELINI PHARMA S P A [IT] · Granted Thu May 30 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Wed May 25 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  16. US 11999753

    Tetrahydropyridopyrimidine pan-KRas inhibitors

    Mirati Therapeutics, Inc. · Granted Tue Jun 04 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 30 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  17. US 11998529

    Non-sedating dexmedetomidine treatment regimens

    BioXcel Therapeutics, Inc. · Granted Tue Jun 04 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 30 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  18. US 11999693

    Synthetic sphingolipid-like molecules, drugs, methods of their synthesis and methods of treatment

    The Regents of the University of California · Granted Tue Jun 04 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 30 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  19. US 11999773

    Anti-BCMA chimeric antigen receptors

    Cartesian Therapeutics, Inc. · Granted Tue Jun 04 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 30 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  20. US 12000839

    Methods for characterizing disulfide bonds

    REGENERON PHARMACEUTICALS, INC. · Granted Tue Jun 04 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 30 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  21. US 11999683

    Lipocationic dendrimers and uses thereof

    The Board of Regents of the University of Texas System · Granted Tue Jun 04 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 30 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  22. US 11998589

    PEGylated peptide amphiphile nanofibers and methods of use

    Northwestern University · Granted Tue Jun 04 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 30 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  23. US 11998513

    Two-part nitric oxide generating topical compositions

    THE REGENTS OF THE UNIVERSITY OF MICHIGAN · Granted Tue Jun 04 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 30 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  24. US 11999747

    Furoquinolinediones as inhibitors of TDP2

    The United States of America as Represented by the Secretary, Dept. of Health and Human Services · Granted Tue Jun 04 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 30 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  25. US 11998557

    Halogenated psilocybin derivatives and methods of using

    Enveric Biosciences Canada Inc. · Granted Tue Jun 04 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 30 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  26. US 11998606

    Compounds and methods for selective proteolysis of glucocorticoid receptors

    The Board of Regents of the University of Texas System · Granted Tue Jun 04 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 30 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  27. US 11999748

    Exatecan derivatives, linker-payloads, and conjugates and thereof

    GENEQUANTUM HEALTHCARE (SUZHOU) CO., LTD. · Granted Tue Jun 04 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 30 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  28. US 12000829

    Selection of patients for combination therapy

    Syndax Pharmaceuticals, Inc. · Granted Tue Jun 04 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 30 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  29. US 11999971

    Stem cell derived islet differentiation

    Vertex Pharmaceuticals Incorporated · Granted Tue Jun 04 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 30 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  30. US 11999799

    Anti-TMPRSS2 antibodies and antigen-binding fragments

    REGENERON PHARMACEUTICALS, INC. · Granted Tue Jun 04 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 30 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  31. US 11999796

    Anti-CD70 chimeric antigen receptors

    The United States of America, as represented by the Secretary, Department of Health and Human Services · Granted Tue Jun 04 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 30 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  32. US 11999778

    VH4 antibodies and compositions comprising the same

    The Board of Regents of the University of Texas System · Granted Tue Jun 04 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 30 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  33. US 11998565

    Trace element compositions, methods of making and use

    American Regent, Inc. · Granted Tue Jun 04 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 30 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  34. US 11999750

    Crystalline forms of (S)-5-benzyl-N-(5-methyl-4-oxo-2,3,4,5-tetrahydropyrido [3,2-B][1,4]oxazepin-3-yl)-4H-1,2,4-triazole-3-carboxamide

    DENALI THERAPEUTICS INC. · Granted Tue Jun 04 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 30 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  35. US 11999727

    Compounds and methods of use

    Tango Therapeutics, Inc. · Granted Tue Jun 04 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 30 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  36. US 11999731

    EGFR dimer disruptors and use of the same

    THE REGENTS OF THE UNIVERSITY OF MICHIGAN · Granted Tue Jun 04 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 30 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  37. US 11999720

    Pyrazolylacylpyrazoline compounds and method for treating pain

    United States Government as represented by the Department of Veterans Affairs · Granted Tue Jun 04 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 30 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  38. US 11998604

    Therapeutic uses for sodium thiosulfate formulations

    Fennec Pharmaceuticals, Inc. · Granted Tue Jun 04 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 30 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  39. US 11998639

    Formulations of (R)-2-amino-3-phenylpropyl carbamate

    AXSOME MALTA LTD. · Granted Tue Jun 04 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 30 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  40. US 11998635

    Targeted extracellular vesicles comprising membrane proteins with engineered glycosylation sites

    Northwestern University · Granted Tue Jun 04 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 30 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  41. US 11998552

    Pharmaceutical compositions comprising meloxicam

    AXSOME THERAPEUTICS, INC. · Granted Tue Jun 04 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 30 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  42. US 11998571

    Pharmaceutical composition comprising stem cell-conditioned medium and exosome isolated therefrom as active ingredient for prevention or treatment of ocular disease

    DESIGNED CELLS CO., LTD. · Granted Tue Jun 04 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 30 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  43. US 11998568

    Processes for production of tumor infiltrating lymphocytes and uses of same in immunotherapy

    Iovance Biotherapeutics, Inc. · Granted Tue Jun 04 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 30 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  44. US 11998576

    Direct-fed microbials

    MICROBIAL DISCOVERY GROUP, LLC · Granted Tue Jun 04 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 30 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  45. US 11998521

    Use of an RXR agonist in treating drug resistant HER2+ cancers

    The Board of Regents of the University of Texas System · Granted Tue Jun 04 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 30 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  46. US 11998520

    Methods for decreasing injuries associated with intraoperative hypotension

    United States Government as represented by the Department of Veterans Affairs · Granted Tue Jun 04 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 30 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  47. US 11998516

    Methods and compositions for treating depression using cyclobenzaprine

    TONIX PHARMA LIMITED · Granted Tue Jun 04 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 30 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  48. US 11998528

    Non-sedating dexmedetomidine treatment regimens

    BioXcel Therapeutics, Inc. · Granted Tue Jun 04 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 30 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

Frequently asked questions

How many pharma patents expire in 2044?

1,766 published patents in our USPTO index have expiration dates falling in calendar year 2044.