Wednesday, June 10, 2026

Intelligence · Patents

Patents expiring in 2042

Annual patent cliff calendar for 2042 — US pharmaceutical patents by expiration date.

Patents
1,738

Quick answer

1,738 indexed pharmaceutical patents have expiration dates in 2042. Browse by soonest expiry with links to assignee companies and related drugs.

  1. US 11414488

    Methods for treating cancer

    BicycleRD Limited · Granted Tue Aug 16 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 11 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  2. US 11413264

    Carbamoyl phenylalaninol analogs and uses thereof

    Jazz Pharmaceuticals Ireland Limited · Granted Tue Aug 16 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 11 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  3. US 11413296

    Viscous budesonide for the treatment of inflammatory diseases of the gastrointestinal tract

    The Regents of the University of California · Granted Tue Aug 16 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 11 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  4. US 11414455

    Toll-like receptor 2 ligands and methods of making and using thereof

    Arizona Board of Regents on Behalf of the University of Arizona · Granted Tue Aug 16 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 11 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  5. US 11413301

    Composition comprising sea cucumber extract as effective ingredient for preventing and treating Bruch's membrane dysfunction-related disease

    Altregen Co., Ltd. · Granted Tue Aug 16 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 11 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  6. US 11413274

    Methods and compositions associated with the granulocyte colony-stimulating factor receptor

    Ligand Pharmaceuticals Incorporated · Granted Tue Aug 16 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 11 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  7. US 11413303

    Methods for treatment of arthritis

    GALECTIN THERAPEUTICS, INC. · Granted Tue Aug 16 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 11 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  8. US 11414379

    SPAK kinase inhibitors as neuroprotective agents

    United States Government as represented by the Department of Veterans Affairs · Granted Tue Aug 16 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 11 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  9. US 11414458

    Identification of MHC class I phospho-peptide antigens from breast cancer utilizing SHLA technology and complementary enrichment strategies

    The Board of Regents of the University of Oklahoma · Granted Tue Aug 16 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 11 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  10. US 11414657

    Modified CRISPR RNA and modified single CRISPR RNA and uses thereof

    Ionis Pharmaceuticals, Inc. · Granted Tue Aug 16 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 11 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  11. US 11414494

    Anti-GITR antibodies and uses thereof

    REGENERON PHARMACEUTICALS, INC. · Granted Tue Aug 16 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 11 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  12. US 11414496

    Anti-CD38 binding domains

    Takeda Pharmaceutical Company Limited · Granted Tue Aug 16 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 11 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  13. US 11413240

    Methylene blue solution for the treatment of oral lesions

    The Board of Regents of the University of Texas System · Granted Tue Aug 16 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 11 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  14. US 11420976

    Heterocyclic compounds as anti-viral agents

    Enanta Pharmaceuticals, Inc. · Granted Tue Aug 23 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 18 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  15. US 11419934

    Use of VDAS to enhance immunomodulating therapies against tumors

    Oncotelic Therapeutics, Inc. · Granted Tue Aug 23 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 18 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  16. US 11419942

    Angiotensinogen (AGT) iRNA compositions and methods of use thereof

    Alnylam Pharmaceuticals, Inc. · Granted Tue Aug 23 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 18 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  17. US 11420936

    Hypoxia inducible factor-2(alpha) inhibitors and their use in the treatment of diseases

    NIKANG THERAPEUTICS, INC. · Granted Tue Aug 23 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 18 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  18. US 11420945

    Solid state forms of Pemafibrate

    TEVA PHARMACEUTICALS INTERNATIONAL GMBH · Granted Tue Aug 23 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 18 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  19. US 11420965

    Pyrimidine compound as JAK kinase inhibitor

    Theravance Biopharma R&D IP, LLC · Granted Tue Aug 23 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 18 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  20. US 11421231

    Modulation of Huntington expression

    Ionis Pharmaceuticals, Inc. · Granted Tue Aug 23 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 18 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  21. US 11419898

    Combinatorial cancer immunotherapy

    Senti Biosciences, Inc. · Granted Tue Aug 23 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 18 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  22. US 11419943

    Polymer-sunitinib conjugates

    Nektar Therapeutics · Granted Tue Aug 23 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 18 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  23. US 11419835

    Method of treatment and prevention of bacterial vaginosis

    Evofem, Inc. · Granted Tue Aug 23 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 18 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  24. US 11419875

    Compounds and compositions for treating hematological disorders

    Aurigene Discovery Technologies Limited · Granted Tue Aug 23 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 18 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  25. US 11419883

    Inhibiting senescent processes in beta cells for the prevention of type 1 diabetes

    The Regents of the University of California · Granted Tue Aug 23 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 18 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  26. US 11419949

    Adeno-associated virus variant capsids and methods of use thereof

    4D MOLECULAR THERAPEUTICS INC. · Granted Tue Aug 23 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 18 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  27. US 11421007

    Zinc finger protein compositions for modulation of huntingtin (Htt)

    Sangamo Therapeutics, Inc. · Granted Tue Aug 23 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 18 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  28. US 11421034

    Combination anti-CSF1R and anti-PD-1 antibody combination therapy for pancreatic cancer

    Five Prime Therapeutics, Inc. · Granted Tue Aug 23 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 18 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  29. US 11421036

    Methods of treating eosinophilic esophagitis by administering an antibody which inhibits interleukin-4 receptor (IL-4R)

    REGENERON PHARMACEUTICALS, INC. · Granted Tue Aug 23 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 18 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  30. US 11421284

    Methods for predicting drug responsiveness in cancer patients

    Allarity Therapeutics Europe ApS · Granted Tue Aug 23 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 18 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  31. US 11422132

    Peptides and uses thereof for diagnosing and treating myasthenia gravis

    The Regents of the University of California · Granted Tue Aug 23 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 18 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  32. US 11421021

    Immunogenic compositions comprising Staphylococcus aureus leukocidin LukA and LukB derived polypeptides

    INTEGRATED BIOTHERAPEUTIC VACCINES, INC. · Granted Tue Aug 23 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 18 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  33. US 11419888

    Composition and method for promoting reduction of heat stress in animals

    Arizona Board of Regents on Behalf of the University of Arizona · Granted Tue Aug 23 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 18 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  34. US 11420931

    Lipid containing formulations

    ARBUTUS BIOPHARMA CORPORATION · Granted Tue Aug 23 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 18 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  35. US 11420929

    Phenoxy acetic acids and phenyl propionic acids as PPAR delta agonists

    VTV THERAPEUTICS LLC · Granted Tue Aug 23 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 18 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  36. US 11420942

    Crystalline forms of [3-(4- {2-butyl-1-[4-(4-chloro-phenoxy)-phenyl]-1H-imidazol-4-yl} -phenoxy)-propyl]-diethyl-amine

    VTV THERAPEUTICS LLC · Granted Tue Aug 23 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 18 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  37. US 11419812

    Methods for delivering etanercept preparations into a lumen of the intestinal tract using a swallowable drug delivery device

    Rani Therapeutics, LLC · Granted Tue Aug 23 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 18 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  38. US 11419844

    Halogenated xanthene composition and method for treating hematologic cancers

    Provectus Pharmatech, Inc. · Granted Tue Aug 23 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 18 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  39. US 11419318

    Genetically modified rat comprising a humanized TRKB locus

    REGENERON PHARMACEUTICALS, INC. · Granted Tue Aug 23 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 18 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  40. US 11419869

    Dosage forms and regimens for amino acid compounds

    Pliant Therapeutics, Inc. · Granted Tue Aug 23 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 18 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  41. US 11421010

    T cells expressing membrane-anchored IL-12 for the treatment of cancer

    The Board of Regents of the University of Texas System · Granted Tue Aug 23 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 18 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  42. WO 2022177965

    COMPOSITIONS NUTRITIONNELLES COMPRENANT DES OLIGOSACCHARIDES DU LAIT HUMAIN ET DE L'IMMUNOGLOBULINE BOVINE

    ABBOTT LAB [US] · Granted Thu Aug 25 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Wed Aug 20 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  43. US 11426467

    Dosage regimes for the administration of an anti-CD25 ADC

    ADC THERAPEUTICS SA · Granted Tue Aug 30 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 25 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  44. US 11427820

    Methods and means for efficient skipping of exon 45 in Duchenne muscular dystrophy pre-mRNA

    BIOMARIN TECHNOLOGIES B.V. · Granted Tue Aug 30 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 25 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  45. US 11427838

    Materials and methods for treatment of myotonic dystrophy type 1 (DM1) and other related disorders

    Vertex Pharmaceuticals Incorporated · Granted Tue Aug 30 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 25 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  46. US 11427823

    Targeted compositions

    ARBUTUS BIOPHARMA CORPORATION · Granted Tue Aug 30 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 25 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  47. US 11427644

    Dual antigen-induced bipartite functional complementation

    Julius-Maximilians-Universitat Wurzburg · Granted Tue Aug 30 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 25 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  48. US 11427634

    Human anti-semaphorin 4D antibody

    VACCINEX, INC. · Granted Tue Aug 30 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 25 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

Frequently asked questions

How many pharma patents expire in 2042?

1,738 published patents in our USPTO index have expiration dates falling in calendar year 2042.