Wednesday, June 10, 2026

Intelligence · Patents

Patents expiring in 2041

Annual patent cliff calendar for 2041 — US pharmaceutical patents by expiration date.

Patents
2,000

Quick answer

2,000 indexed pharmaceutical patents have expiration dates in 2041. Browse by soonest expiry with links to assignee companies and related drugs.

  1. US 10954289

    Anti-SARS-CoV-2-spike glycoprotein antibodies and antigen-binding fragments

    REGENERON PHARMACEUTICALS, INC. · Granted Tue Mar 23 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Mar 18 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  2. US 10953031

    Compounds and methods for treating neurological and cardiovascular conditions

    The Board of Regents of the University of Texas System · Granted Tue Mar 23 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Mar 18 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  3. US 10953046

    Processes for production of tumor infiltrating lymphocytes and uses of same in immunotherapy

    Iovance Biotherapeutics, Inc. · Granted Tue Mar 23 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Mar 18 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  4. US 10954268

    Method of treating melanocortin-4 receptor-associated disorders in heterozygous carriers

    RHYTHM PHARMACEUTICALS, INC. · Granted Tue Mar 23 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Mar 18 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  5. US 10954291

    Monoclonal antibodies that specifically bind to matrilin-3 and their use

    The United States of America, as represented by the Secretary, Department of Health and Human Services · Granted Tue Mar 23 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Mar 18 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  6. US 10954516

    GNAQ targeted dsRNA compositions and methods for inhibiting expression

    Alnylam Pharmaceuticals, Inc. · Granted Tue Mar 23 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Mar 18 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  7. US 10953003

    Methods for treating cancer

    X4 Pharmaceuticals, Inc. · Granted Tue Mar 23 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Mar 18 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  8. US 10954294

    Correctly folded etanercept in high purity and excellent yield

    Coherus BioSciences, Inc. · Granted Tue Mar 23 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Mar 18 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  9. US 10954529

    Minimal volume reprogramming of mononuclear cells

    Fate Therapeutics, Inc. · Granted Tue Mar 23 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Mar 18 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  10. US 10954498

    Modified cascade ribonucleoproteins and uses thereof

    Caribou Biosciences, Inc. · Granted Tue Mar 23 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Mar 18 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  11. US 10954259

    Preparation of psilocybin, different polymorphic forms, intermediates, formulations and their use

    Compass Pathfinder Limited · Granted Tue Mar 23 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Mar 18 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  12. US 10954295

    Correctly folded etanercept in high purity and excellent yield

    Coherus BioSciences, Inc. · Granted Tue Mar 23 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Mar 18 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  13. US 10954198

    Benzylideneguanidine derivatives and therapeutic use for the treatment of protein misfolding diseases

    United Kingdom Research and Innovation · Granted Tue Mar 23 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Mar 18 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  14. US 10953209

    Treating tumors using TTFields combined with a PARP inhibitor

    The Board of Regents of the University of Texas System · Granted Tue Mar 23 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Mar 18 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  15. US 10954304

    Neutralizing antibodies to the αvβ8 integrin complex for immunotherapy

    The Regents of the University of California · Granted Tue Mar 23 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Mar 18 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  16. US 10953047

    Processes for production of tumor infiltrating lymphocytes and uses of same in immunotherapy

    Iovance Biotherapeutics, Inc. · Granted Tue Mar 23 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Mar 18 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  17. US 10953040

    Methods of treating bacterial infections with penam β-lactam antibiotics and branched poly(ethylenimine)

    The Board of Regents of the University of Oklahoma · Granted Tue Mar 23 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Mar 18 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  18. US 10953018

    Emulsion formulations of aprepitant

    Heron Therapeutics, Inc. · Granted Tue Mar 23 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Mar 18 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  19. US 10952996

    ALK5 inhibitors

    Theravance Biopharma R&D IP, LLC · Granted Tue Mar 23 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Mar 18 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  20. US 10952978

    Hepatitis B antiviral agents

    Enanta Pharmaceuticals, Inc. · Granted Tue Mar 23 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Mar 18 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  21. US 10954192

    Pyrrolomycins and methods of using the same

    BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA · Granted Tue Mar 23 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Mar 18 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  22. US 10952993

    Therapeutic uses of glucokinase activators in combination with insulin or insulin analogs

    VTV THERAPEUTICS LLC · Granted Tue Mar 23 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Mar 18 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  23. US 10954530

    Retroviral and lentiviral vectors

    AUTOLUS LIMITED · Granted Tue Mar 23 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Mar 18 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  24. US 10953026

    N-acetyl mannosammine as a therapeutic agent

    The United States of America, as represented by the Secretary, Department of Health and Human Services · Granted Tue Mar 23 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Mar 18 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  25. WO 2021052960

    COMPOSITION RADIOPHARMACEUTIQUE CONCENTRÉE, STABLE

    ADVANCED ACCELERATOR APPLICATIONS ITALY SRL [IT] · Granted Thu Mar 25 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Wed Mar 20 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  26. WO 2021053040

    MÉTHODES DE RADIOMARQUAGE D'ANTAGONISTES DE GRPR ET LEURS KITS

    ADVANCED ACCELERATOR APPLICATIONS ITALY SRL [IT] · Granted Thu Mar 25 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Wed Mar 20 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  27. US 10961232

    Substituted pyrazines as ATR kinase inhibitors

    Vertex Pharmaceuticals Incorporated · Granted Tue Mar 30 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Mar 25 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  28. US 10961238

    Modulators of hedgehog (Hh) signaling pathway

    E-Therapeutics PLC · Granted Tue Mar 30 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Mar 25 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  29. US 10960051

    Methods of treating dry eye syndrome

    REGENTREE, LLC · Granted Tue Mar 30 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Mar 25 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  30. US 10960085

    Modulation of liver genes

    Sangamo Therapeutics, Inc. · Granted Tue Mar 30 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Mar 25 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  31. US 10959952

    Use of exosomes for the treatment of disease

    The Board of Regents of the University of Texas System · Granted Tue Mar 30 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Mar 25 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  32. US 10959956

    Controlled release dosage forms for high dose, water soluble and hygroscopic drug substances

    Jazz Pharmaceuticals, Inc. · Granted Tue Mar 30 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Mar 25 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  33. US 10961301

    Cell-penetrating anti-DNA antibodies and uses thereof inhibit DNA repair

    The United States Government represented by the Department of Veterans Affairs · Granted Tue Mar 30 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Mar 25 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  34. US 10961283

    Self-assembling insect ferritin nanoparticles for display of co-assembled trimeric antigens

    The United States of America, as represented by the Secretary, Department of Health and Human Services · Granted Tue Mar 30 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Mar 25 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  35. US 10960029

    Devices and methods for umbilical cord processing

    The Board of Regents of the University of Texas System · Granted Tue Mar 30 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Mar 25 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  36. US 10959988

    Crystalline forms of 3-[5-(2-fluorophenyl)-[1,2,4]oxadiazol-3-yl]-benzoic acid for the treatment of disease

    PTC THERAPEUTICS, INC. · Granted Tue Mar 30 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Mar 25 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  37. US 10961282

    Variant adeno-associated viruses and methods of using

    The Regents of the University of California · Granted Tue Mar 30 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Mar 25 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  38. US 10961205

    1,2,4-oxadiazole derivatives as immunomodulators

    Aurigene Discovery Technologies Limited · Granted Tue Mar 30 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Mar 25 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  39. US 10960044

    Powder formulation having hypoglycemic and hypolipidemic functions and method for preparing the same

    INFINITUS (CHINA) COMPANY LTD. · Granted Tue Mar 30 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Mar 25 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  40. US 10959984

    Methods for treating cancer with RORγ inhibitors

    The Regents of the University of California · Granted Tue Mar 30 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Mar 25 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  41. US 10959938

    Combination of (3S,3S′) 4,4′-disulfanediylbis(3-aminobutane 1-sulfonic acid) and a second antihypertensive agent

    QUANTUM GENOMICS · Granted Tue Mar 30 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Mar 25 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  42. US 10960039

    Composition, preparation method and use of the same in manufacture of a product for relieving thyroid nodules

    INFINITUS (CHINA) COMPANY LTD. · Granted Tue Mar 30 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Mar 25 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  43. US 10960000

    Abuse resistant pharmaceutical compositions

    RECRO GAINESVILLE LLC · Granted Tue Mar 30 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Mar 25 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  44. US 10960079

    Conjugates of an IL-2 moiety and a polymer

    Nektar Therapeutics · Granted Tue Mar 30 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Mar 25 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  45. US 10959976

    Methods and compositions for treating excessive sleepiness

    Jazz Pharmaceuticals Ireland Limited · Granted Tue Mar 30 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Mar 25 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  46. US 10960016

    Capsules containing high doses of krill phospholipids

    AKER BIOMARINE ANTARCTIC AS · Granted Tue Mar 30 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Mar 25 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  47. US 10960046

    Method of treating melanocortin-4 receptor pathway-associated disorders

    RHYTHM PHARMACEUTICALS, INC. · Granted Tue Mar 30 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Mar 25 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  48. US 10960045

    Methods and compositions for the treatment of epidermolysis bullosa

    Compass Therapeutics LLC · Granted Tue Mar 30 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Mar 25 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

Frequently asked questions

How many pharma patents expire in 2041?

2,000 published patents in our USPTO index have expiration dates falling in calendar year 2041.