Wednesday, June 10, 2026

Intelligence · Patents

Patents expiring in 2041

Annual patent cliff calendar for 2041 — US pharmaceutical patents by expiration date.

Patents
2,000

Quick answer

2,000 indexed pharmaceutical patents have expiration dates in 2041. Browse by soonest expiry with links to assignee companies and related drugs.

  1. US 10961205

    1,2,4-oxadiazole derivatives as immunomodulators

    Aurigene Discovery Technologies Limited · Granted Tue Mar 30 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Mar 25 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  2. US 10960044

    Powder formulation having hypoglycemic and hypolipidemic functions and method for preparing the same

    INFINITUS (CHINA) COMPANY LTD. · Granted Tue Mar 30 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Mar 25 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  3. US 10959984

    Methods for treating cancer with RORγ inhibitors

    The Regents of the University of California · Granted Tue Mar 30 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Mar 25 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  4. US 10959938

    Combination of (3S,3S′) 4,4′-disulfanediylbis(3-aminobutane 1-sulfonic acid) and a second antihypertensive agent

    QUANTUM GENOMICS · Granted Tue Mar 30 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Mar 25 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  5. US 10960039

    Composition, preparation method and use of the same in manufacture of a product for relieving thyroid nodules

    INFINITUS (CHINA) COMPANY LTD. · Granted Tue Mar 30 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Mar 25 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  6. US 10959976

    Methods and compositions for treating excessive sleepiness

    Jazz Pharmaceuticals Ireland Limited · Granted Tue Mar 30 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Mar 25 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  7. US 10960046

    Method of treating melanocortin-4 receptor pathway-associated disorders

    RHYTHM PHARMACEUTICALS, INC. · Granted Tue Mar 30 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Mar 25 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  8. US 10960051

    Methods of treating dry eye syndrome

    REGENTREE, LLC · Granted Tue Mar 30 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Mar 25 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  9. US 10961535

    Compositions and agents against hepatitis B virus and uses thereof

    ARCTURUS THERAPEUTICS, INC. · Granted Tue Mar 30 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Mar 25 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  10. US 10960079

    Conjugates of an IL-2 moiety and a polymer

    Nektar Therapeutics · Granted Tue Mar 30 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Mar 25 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  11. WO 2021058549

    ANTAGONISTE GRPR RADIOMARQUÉ POUR L'UTILISATION COMME AGENT THÉRAGNOSTIQUE

    ADVANCED ACCELERATOR APPLICATIONS ITALY SRL [IT] · Granted Thu Apr 01 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Wed Mar 27 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  12. CA 3156009

    POLYTHERAPIE AVEC DES ANTAGONISTES DU CGRP

    ALLERGAN PHARMACEUTICALS INT LTD [IE] · Granted Thu Apr 01 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Wed Mar 27 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  13. US 10968261

    Methods and compositions for genome engineering

    Sangamo Therapeutics, Inc. · Granted Tue Apr 06 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Apr 01 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  14. US 10968442

    Chimeric clotting factors

    BIOVERATIV THERAPEUTICS INC. · Granted Tue Apr 06 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Apr 01 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  15. US 10967346

    Microspheres and method for producing them

    Shenkar Engineering Design Art · Granted Tue Apr 06 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Apr 01 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  16. US 10968166

    4-(P-quinonyl)-2-hydroxybutanamide derivatives for treatment of mitochondrial diseases

    PTC THERAPEUTICS, INC. · Granted Tue Apr 06 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Apr 01 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  17. US 10968178

    IP6K inhibitors

    Takeda Pharmaceutical Company Limited · Granted Tue Apr 06 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Apr 01 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  18. US 10968180

    Piperidine derivatives as HDAC1/2 inhibitors

    Regenacy Pharmaceuticals, Inc. · Granted Tue Apr 06 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Apr 01 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  19. US 10967017

    Traditional Chinese medicine composition and use thereof

    INFINITUS (CHINA) COMPANY LTD. · Granted Tue Apr 06 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Apr 01 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  20. US 10967058

    Foot-and-mouth disease vaccine

    United States of America as represented by the Secretary of the Air Force · Granted Tue Apr 06 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Apr 01 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  21. US 10967051

    Methods and compositions for treating NAFLD, hepatic steatosis, and sequelae thereof

    Oramed Ltd. · Granted Tue Apr 06 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Apr 01 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  22. US 10967065

    Compounds for treating biofilm infection

    The Board of Regents of the University of Texas System · Granted Tue Apr 06 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Apr 01 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  23. US 10967072

    Short interfering RNA templated lipoprotein particles (siRNA-TLP)

    Northwestern University · Granted Tue Apr 06 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Apr 01 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  24. US 10968201

    Bicyclic carboxamides and methods of use thereof

    TEMPEST THERAPEUTICS, INC. · Granted Tue Apr 06 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Apr 01 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  25. US 10968203

    Pyrimidinyl-pyridyloxy-naphthyl compounds and methods of treating IRE1-related diseases and disorders

    The Regents of the University of California · Granted Tue Apr 06 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Apr 01 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  26. US 10968213

    Cyclopropanamine compound and use thereof

    Takeda Pharmaceutical Company Limited · Granted Tue Apr 06 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Apr 01 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  27. US 10968206

    Cannabinergic nitrate esters and related analogs

    Northwestern University · Granted Tue Apr 06 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Apr 01 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  28. US 10968222

    2-azabicyclo hexane JAK inhibitor compound

    Theravance Biopharma R&D IP, LLC · Granted Tue Apr 06 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Apr 01 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  29. US 10967062

    Functionalized nanoparticles and methods of use thereof

    Regents of the University of Minnesota · Granted Tue Apr 06 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Apr 01 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  30. US 10966977

    Combination of anti-CD20 antibody, P13 kinase-delta selective inhibitor, and BTK inhibitor to treat b-cell proliferative disorders

    TG Therapeutics, Inc. · Granted Tue Apr 06 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Apr 01 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  31. US 10968211

    Hepatitis B core protein modulators

    ASSEMBLY BIOSCIENCES, INC. · Granted Tue Apr 06 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Apr 01 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  32. US 10968231

    Substituted cyclyl-acetic acid derivatives for the treatment of metabolic disorders

    Takeda Pharmaceutical Company Limited · Granted Tue Apr 06 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Apr 01 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  33. US 10968495

    Lactobacillus reuteri and use thereof

    INFINITUS (CHINA) COMPANY LTD. · Granted Tue Apr 06 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Apr 01 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  34. US 10968249

    Bile acid derivatives as FXR/TGR5 agonists and methods of use thereof

    Enanta Pharmaceuticals, Inc. · Granted Tue Apr 06 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Apr 01 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  35. US 10968205

    Pyrazolo and triazolo bicyclic compounds as JAK kinase inhibitors

    Theravance Biopharma R&D IP, LLC · Granted Tue Apr 06 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Apr 01 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  36. US 10967063

    Surfactant-free, water-free formable composition and breakable foams and their uses

    Vyne Therapeutics Inc. · Granted Tue Apr 06 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Apr 01 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  37. US 10967016

    Traditional Chinese medicine composition and use thereof

    INFINITUS (CHINA) COMPANY LTD. · Granted Tue Apr 06 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Apr 01 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  38. US 10966931

    Controlled release dosage forms for high dose, water soluble and hygroscopic drug substances

    Jazz Pharmaceuticals, Inc. · Granted Tue Apr 06 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Apr 01 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  39. US 10968248

    Trinucleotide mRNA cap analogs

    Arcturus, Inc. · Granted Tue Apr 06 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Apr 01 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  40. US 10968452

    Polynucleotide agents targeting aminolevulinic acid synthase-1 (ALAS1) and uses thereof

    Alnylam Pharmaceuticals, Inc. · Granted Tue Apr 06 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Apr 01 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  41. US 10968278

    Compositions comprising IL6R antibodies for the treatment of uveitis and macular edema and methods of using same

    REGENERON PHARMACEUTICALS, INC. · Granted Tue Apr 06 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Apr 01 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  42. US 10966970

    Fused tricyclic compounds and uses thereof in medicine

    SUNSHINE LAKE PHARMA CO., LTD. · Granted Tue Apr 06 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Apr 01 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  43. US 10967050

    Therapeutic agent preparations for delivery into a lumen of the intestinal tract using a swallowable drug delivery device

    Rani Therapeutics, LLC · Granted Tue Apr 06 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Apr 01 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  44. US 10966950

    Use of an RXR agonist in treating HER2+ cancers

    The Board of Regents of the University of Texas System · Granted Tue Apr 06 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Apr 01 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  45. US 10967011

    Compositions and methods

    Seres Therapeutics, Inc. · Granted Tue Apr 06 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Apr 01 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  46. WO 2021064188

    COMBINAISON COMPRENANT UN INHIBITEUR DE HDAC, UN INHIBITEUR DE CTLA-4 ET UN INHIBITEUR DE PD-1 OU UN INHIBITEUR DE PD-L1 POUR LE TRAITEMENT DU CANCER

    4SC AG [DE] · Granted Thu Apr 08 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Wed Apr 03 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  47. CN 112638413

    Oral immunotherapy unit dose dispensing systems and methods

    ALLERGEN RES CORPORATION · Granted Fri Apr 09 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Thu Apr 04 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  48. US 10975388

    Methods and compositions for nucleic acid and protein payload delivery

    LIGANDAL, INC. · Granted Tue Apr 13 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Apr 08 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

Frequently asked questions

How many pharma patents expire in 2041?

2,000 published patents in our USPTO index have expiration dates falling in calendar year 2041.