Wednesday, June 10, 2026

Intelligence · Patents

Patents expiring in 2041

Annual patent cliff calendar for 2041 — US pharmaceutical patents by expiration date.

Patents
2,000

Quick answer

2,000 indexed pharmaceutical patents have expiration dates in 2041. Browse by soonest expiry with links to assignee companies and related drugs.

  1. US 11174219

    Neprilysin inhibitors

    Theravance Biopharma R&D IP, LLC · Granted Tue Nov 16 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 11 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  2. US 11174212

    2,3,5-trimelthyl-6-nonylcyclohexa-2,5-diene-1,4-dione for suppressing and treating alpha-synucleinopathies, tauopathies, and other disorders

    PTC THERAPEUTICS, INC. · Granted Tue Nov 16 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 11 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  3. US 11174272

    1-arylcarbonyl-4-oxy-piperidine compounds useful for the treatment of neurodegenerative diseases

    Takeda Pharmaceutical Company Limited · Granted Tue Nov 16 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 11 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  4. US 11173227

    Wound dressings and applications thereof

    The Board of Regents of the University of Texas System · Granted Tue Nov 16 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 11 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  5. US 11173173

    Methods for treating chemoresistant cancer-initiating cells

    UNIVERSITY OF CONNECTICUT · Granted Tue Nov 16 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 11 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  6. US 11173318

    Method of repairing age and disease immune dysfunction and cellular senescence with lymphoid stem cells and then re-applying those for therapeutic use

    Advanced Neuroregenerative Therapies, LLC. · Granted Tue Nov 16 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 11 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  7. US 11174232

    Substituted heterocyclyl derivatives as CDK inhibitors

    Aurigene Discovery Technologies Limited · Granted Tue Nov 16 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 11 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  8. US 11174291

    Silstatin compounds

    ARIZONA BOARD OF REGENTS FOR AND ON BEHALF OF ARIZONA STATE UNIVERSITY · Granted Tue Nov 16 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 11 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  9. US 11173118

    Emulsion formulations of an NK-1 receptor antagonist and uses thereof

    Heron Therapeutics, Inc. · Granted Tue Nov 16 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 11 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  10. US 11173146

    Selective activators of the intermediate conductance CA2+activated K+ channel KCa3.1 and their methods of use

    The Regents of the University of California · Granted Tue Nov 16 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 11 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  11. US 11173129

    Nanowire-coated microdevice and method of making and using the same

    The Regents of the University of California · Granted Tue Nov 16 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 11 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  12. US 11173136

    Method for modulating metabolism

    Brightseed, Inc. · Granted Tue Nov 16 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 11 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  13. US 11173164

    Compositions comprising triterpenoids

    REGENERA PHARMA LTD. · Granted Tue Nov 16 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 11 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  14. US 11173208

    Liquid formulation comprising GM-CSF neutralizing compound

    TAKEDA GMBH · Granted Tue Nov 16 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 11 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  15. US 11173291

    Implantable drug delivery devices for localized drug delivery

    The Regents of the University of California · Granted Tue Nov 16 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 11 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  16. US 11173235

    Nitrite eluting devices and methods of use thereof

    Cook Regentec LLC · Granted Tue Nov 16 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 11 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  17. US 11173183

    Compositions for fecal floral transplantation and methods for making and using them and devices for delivering them

    Finch Therapeutics Holdings LLC · Granted Tue Nov 16 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 11 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  18. US 11173100

    Multi-part dental cement

    KURARAY NORITAKE DENTAL INC. · Granted Tue Nov 16 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 11 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  19. US 11172694

    Core-shell structure with titanium dioxide core

    SOLID CHEMICALS GMBH · Granted Tue Nov 16 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 11 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  20. CA 3172190

    COMPOSITION COMPRENANT DU METHYLFOLATE

    ALFASIGMA SPA [IT] · Granted Thu Nov 18 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Wed Nov 13 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  21. CA 3177888

    ANTICORPS ANTI-HEMOJUVELINE (HJV) DE TRAITEMENT DE L'ANEMIE DE MALADIES CHRONIQUES

    DISC MEDICINE INC [US] · Granted Thu Nov 18 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Wed Nov 13 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  22. CA 3177686

    COMPOSITIONS COMPRENANT DE LA TROPOELASTINE RETICULEE A DE L'ACIDE HYALURONIQUE ET LEURS PROCEDES D'UTILISATION

    ALLERGAN PHARMACEUTICALS INT LTD [IE] · Granted Thu Nov 18 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Wed Nov 13 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  23. CA 3172871

    COMPOSITIONS DE POLYPEPTIDES DE FUSION D'IL-2 ET LEURS PROCEDES DE FABRICATION ET D'UTILISATION

    ALKERMES PHARMA IRELAND LTD [IE] · Granted Thu Nov 18 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Wed Nov 13 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  24. CA 3172874

    COMPOSITIONS DE POLYPEPTIDES DE FUSION D'IL-2 ET LEURS PROCEDES DE FABRICATION ET D'UTILISATION

    ALKERMES PHARMA IRELAND LTD [IE] · Granted Thu Nov 18 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Wed Nov 13 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  25. US 11179327

    Compositions and methods for the treatment of presbyopia

    Lenz Therapeutics, Inc. · Granted Tue Nov 23 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 18 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  26. US 11179320

    Self-regulating osmotic gastroretentive drug delivery systems

    Amneal Complex Products Research LLC · Granted Tue Nov 23 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 18 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  27. US 11179328

    Compositions and methods for the treatment of presbyopia

    Lenz Therapeutics, Inc. · Granted Tue Nov 23 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 18 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  28. US 11179370

    Cannabinoid receptor antagonists/inverse agonists useful for treating disease conditions, including metabolic disorders and cancers

    Jenrin Discovery, LLC · Granted Tue Nov 23 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 18 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  29. US 11179394

    Method for treating cancer using a combination of Chk1 and ATR inhibitors

    Vertex Pharmaceuticals Incorporated · Granted Tue Nov 23 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 18 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  30. US 11179477

    Method of using adeno-associated virus with variant capsid

    4D MOLECULAR THERAPEUTICS INC. · Granted Tue Nov 23 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 18 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  31. US 11180483

    Substituted reverse pyrimidine Bmi-1 inhibitors

    PTC THERAPEUTICS, INC. · Granted Tue Nov 23 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 18 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  32. US 11180517

    Preparation of psilocybin, different polymorphic forms, intermediates, formulations and their use

    Compass Pathfinder Limited · Granted Tue Nov 23 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 18 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  33. US 11181520

    Systems and methods for high-resolution imaging

    The Board of Regents of the University of Texas System · Granted Tue Nov 23 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 18 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  34. US 11180518

    Phenyl-heterocycle-phenyl derivatives for use in the treatment or prevention of melanoma

    Ludwig-Maximilians-Universitat Munchen · Granted Tue Nov 23 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 18 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  35. US 11180562

    Method of treating or delaying progression of an epidermal growth factor receptor (EGFR)-related disorder by administering activatable EGFR-binding antibodies

    CytomX Therapeutics, Inc. · Granted Tue Nov 23 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 18 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  36. US 11180531

    Bicyclic peptide ligands specific for Nectin-4

    BicycleTx Limited · Granted Tue Nov 23 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 18 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  37. US 11180529

    Alpha-v beta-6 integrin ligands and uses thereof

    Arrowhead Pharmaceuticals, Inc. · Granted Tue Nov 23 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 18 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  38. US 11180499

    Phosphodiesterase inhibitors

    BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA · Granted Tue Nov 23 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 18 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  39. US 11179435

    Hangover alleviating composition containing conjugate of sesamol and peptide as active ingredient

    CAREGEN CO., LTD. · Granted Tue Nov 23 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 18 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  40. US 11179439

    Methods and compositions for preventing and treating damage to the heart

    The Regents of the University of California · Granted Tue Nov 23 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 18 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  41. US 11179400

    Heterocyclic compounds as RSV inhibitors

    Enanta Pharmaceuticals, Inc. · Granted Tue Nov 23 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 18 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  42. US 11179419

    Restimulation of cryopreserved tumor infiltrating lymphocytes

    Iovance Biotherapeutics, Inc. · Granted Tue Nov 23 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 18 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  43. US 11179467

    Exenatide modifier and use thereof

    BrightGene Bio-Medical Technology Co., Ltd. · Granted Tue Nov 23 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 18 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  44. US 11179486

    Wet wiper

    KURARAY KURAFLEX CO., LTD. · Granted Tue Nov 23 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 18 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  45. US 11179494

    Collagenous tissue repair device

    Northwestern University · Granted Tue Nov 23 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 18 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  46. US 11180452

    Methods and compositions for selectively inhibiting pathogenic microbes

    The Board of Regents of the University of Oklahoma · Granted Tue Nov 23 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 18 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  47. US 11180444

    Polyimino ketoaldehydes

    NOVUM SPERO LTD · Granted Tue Nov 23 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 18 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  48. US 11180466

    2-benzoylaminobenzamide derivatives as Bcl-3 inhibitors

    University College Cardiff Consultants Limited · Granted Tue Nov 23 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 18 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

Frequently asked questions

How many pharma patents expire in 2041?

2,000 published patents in our USPTO index have expiration dates falling in calendar year 2041.