Wednesday, June 10, 2026
🇺🇸 FDA

Intelligence · Patents

Patents expiring in 2041

Annual patent cliff calendar for 2041 — US pharmaceutical patents by expiration date.

Patents
2,000

Quick answer

2,000 indexed pharmaceutical patents have expiration dates in 2041. Browse by soonest expiry with links to assignee companies and related drugs.

  1. US 11000562

    Use of isolated fractions of mastic gum for treating optic neuropathy

    REGENERA PHARMA LTD. · Granted Tue May 11 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 06 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  2. US 11000520

    Buprenorphine dosing regimens

    Indivior UK Limited · Granted Tue May 11 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 06 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  3. US 11000568

    Means and methods for treating copper-related diseases

    THE REGENTS OF THE UNIVERSITY OF MICHIGAN · Granted Tue May 11 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 06 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  4. US 11001627

    Correctly folded etanercept in high purity and excellent yield

    Coherus BioSciences, Inc. · Granted Tue May 11 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 06 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  5. US 11000409

    Devices and methods for slurry generation

    MIRAKI INNOVATION THINK TANK LLC · Granted Tue May 11 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 06 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  6. US 11000595

    Modulators of PCSK9 expression

    Ionis Pharmaceuticals, Inc. · Granted Tue May 11 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 06 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  7. US 11000599

    Peptidic self-assembly for nucleic acid delivery

    S. M. DISCOVERY GROUP INC. · Granted Tue May 11 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 06 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  8. US 11000517

    Dosage and formulation

    Almirall, S.A. · Granted Tue May 11 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 06 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  9. US 11000588

    Etanercept formulations stabilized with sodium chloride

    Coherus BioSciences, Inc. · Granted Tue May 11 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 06 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  10. US 11000600

    Exon skipping oligomer conjugates for muscular dystrophy

    Sarepta Therapeutics, Inc. · Granted Tue May 11 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 06 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  11. US 11000602

    Delivery of small interfering RNA and micro RNA through nanogels containing hydrophobic pseudo-peptides

    The Board of Regents of the University of Texas System · Granted Tue May 11 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 06 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  12. US 11008337

    Chiral diaryl macrocycles as modulators of protein kinases

    TURNING POINT THERAPEUTICS, INC. · Granted Tue May 18 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 13 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  13. US 11007183

    Cancer treatments using combinations of PI3K/Akt pathway and ERK inhibitors

    Biomed Valley Discoveries, Inc. · Granted Tue May 18 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 13 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  14. US 11007184

    Cancer treatments using combinations of type 2 MEK and ERK inhibitors

    Biomed Valley Discoveries, Inc. · Granted Tue May 18 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 13 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  15. US 11007163

    Glutarate compounds for treating ischemia-reperfusion injuries

    The Regents of the University of California · Granted Tue May 18 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 13 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  16. US 11007193

    2,4-pyrimidinediamine compounds and their uses

    Rigel Pharmaceuticals, Inc. · Granted Tue May 18 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 13 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  17. US 11007186

    Methods of treating RBP4 related diseases with triazolopyridines

    Belite Bio, Inc · Granted Tue May 18 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 13 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  18. US 11007248

    Suppression of allergic lung inflammation and hyperreactivity

    The Regents of the University of California · Granted Tue May 18 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 13 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  19. US 11007201

    Corticotropin releasing factor receptor antagonists

    SPRUCE BIOSCIENCES, INC. · Granted Tue May 18 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 13 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  20. US 11008325

    Inhibitors of cancer invasion, attachment, and/or metastasis

    SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE · Granted Tue May 18 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 13 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  21. US 11008360

    Indoleacetic acid derivative and preparation method and pharmaceutical use thereof

    Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences · Granted Tue May 18 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 13 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  22. US 11008334

    Compositions and methods for treating cancer

    The Regents of the University of California · Granted Tue May 18 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 13 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  23. US 11007254

    Compositions and methods for treating central nervous system injury

    United States Government as represented by the Department of Veterans Affairs · Granted Tue May 18 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 13 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  24. US 11007226

    Processes for production of tumor infiltrating lymphocytes and uses of same in immunotherapy

    Iovance Biotherapeutics, Inc. · Granted Tue May 18 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 13 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  25. US 11008309

    Substituted benzofuranyl and benzoxazolyl compounds and uses thereof

    Karyopharm Therapeutics Inc. · Granted Tue May 18 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 13 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  26. US 11008564

    Processing engineered FMDV P1 polypeptide using an alternative TEV protease

    The Government of the United States of America, as represented by the Secretary of Homeland Security · Granted Tue May 18 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 13 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  27. US 11008381

    Antibodies to oxidized phospholipids

    The Regents of the University of California · Granted Tue May 18 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 13 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  28. US 11008314

    Compounds and methods for modulating interleukin-2-inducible t-cell kinase

    Corvus Pharmaceuticals, Inc. · Granted Tue May 18 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 13 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  29. US 11008304

    Tetrazole containing apoptosis signal-regulating kinase 1 inhibitors and methods of use thereof

    Enanta Pharmaceuticals, Inc. · Granted Tue May 18 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 13 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  30. US 11007261

    Compositions and methods of vaccination against dengue virus in children and young adults

    Takeda Vaccines, Inc. · Granted Tue May 18 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 13 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  31. US 11007217

    Compositions comprising nanosilica particles and their use in methods of activating T lymphocytes for therapy

    United Kingdom Research and Innovation · Granted Tue May 18 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 13 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  32. US 11007171

    Treatment and prevention of joint disorders

    Summit Innovation Labs LLC · Granted Tue May 18 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 13 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  33. US 11006626

    Compounds for protection of cells

    Sulfateq B.V. · Granted Tue May 18 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 13 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  34. US 11008305

    DNA-PK inhibitors

    Vertex Pharmaceuticals Incorporated · Granted Tue May 18 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 13 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  35. US 11008378

    Compositions and methods for immunomodulation in an organism

    UNIVERSITY OF CONNECTICUT · Granted Tue May 18 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 13 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  36. US 11008372

    Targeting proteins for degradation

    The Board of Regents of the University of Texas System · Granted Tue May 18 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 13 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  37. US 11007385

    Use of cellular extracts for skin rejuvenation

    REGENICS AS · Granted Tue May 18 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 13 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  38. US 11007157

    Toxic aldehyde related diseases and treatment

    Aldeyra Therapeutics, Inc. · Granted Tue May 18 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 13 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  39. US 11007270

    Polymer-semaxanib moiety conjugates

    Nektar Therapeutics · Granted Tue May 18 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 13 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  40. US 11007249

    Compositions comprising pregnancy specific glycoproteins and methods of use thereof

    The United States of America, as represented by the Secretary, Department of Health and Human Services · Granted Tue May 18 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 13 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  41. US 11007265

    Vaccines having an antigen and interleukin-21 as an adjuvant

    Inovio Pharmaceuticals, Inc. · Granted Tue May 18 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 13 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  42. US 11007147

    Hydrogel toxin-absorbing or binding nanoparticles

    The Regents of the University of California · Granted Tue May 18 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 13 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  43. US 11007255

    Cancer vaccines and methods of treatment using the same

    Inovio Pharmaceuticals, Inc. · Granted Tue May 18 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 13 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  44. US 11008553

    Halogenation of complex organic compounds

    THE REGENTS OF THE UNIVERSITY OF MICHIGAN · Granted Tue May 18 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 13 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  45. US 11008289

    Crystalline freebase forms of a biphenyl compound

    Theravance Biopharma R&D IP, LLC · Granted Tue May 18 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 13 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  46. US 11007263

    Development of a novel live attenuated African Swine Fever vaccine based in the deletion of gene I177L

    The United States of America, as represented by the Secretary of Agriculture · Granted Tue May 18 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 13 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  47. US 11007281

    Nano/micromotors for active and dynamic intracellular payload delivery

    The Regents of the University of California · Granted Tue May 18 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 13 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  48. US 11008551

    Method to increase the infectivity of virus particles

    THE TRUSTEES OF PRINCETON UNIVERSITY · Granted Tue May 18 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 13 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

Frequently asked questions

How many pharma patents expire in 2041?

2,000 published patents in our USPTO index have expiration dates falling in calendar year 2041.

Drug approvals, clinical trials, M&A, event intelligence, and company updates — weekly.

Customize topics & region
Topics
Region

No spam. Unsubscribe anytime. See our privacy policy.