Wednesday, June 10, 2026

Intelligence · Patents

Patents expiring in 2041

Annual patent cliff calendar for 2041 — US pharmaceutical patents by expiration date.

Patents
2,000

Quick answer

2,000 indexed pharmaceutical patents have expiration dates in 2041. Browse by soonest expiry with links to assignee companies and related drugs.

  1. US 10995335

    RNAi agents and compositions for inhibiting expression of angiopoietin-like 3 (ANGPTL3), and methods of use

    Arrowhead Pharmaceuticals, Inc. · Granted Tue May 04 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Apr 29 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  2. US 10995328

    Materials and methods for treatment of autosomal dominant cone-rod dystrophy

    CRISPR THERAPEUTICS AG · Granted Tue May 04 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Apr 29 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  3. US 10995150

    Methods for inhibiting atherosclerosis by administering an anti-PCSK9 antibody

    REGENERON PHARMACEUTICALS, INC. · Granted Tue May 04 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Apr 29 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  4. US 10995100

    Bicyclic heterocyclyl derivatives as IRAK4 inhibitors

    Aurigene Discovery Technologies Limited · Granted Tue May 04 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Apr 29 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  5. US 10995156

    Acid-degradable and bioerodible modified polyhydroxylated materials

    The Regents of the University of California · Granted Tue May 04 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Apr 29 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  6. US 10995061

    SPAK kinase inhibitors as neuroprotective agents

    United States Government as represented by the Department of Veterans Affairs · Granted Tue May 04 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Apr 29 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  7. US 10994014

    Bacterially derived, intact minicells for delivery of therapeutic agents to brain tumors

    EnGeneIC Molecular Delivery Pty Ltd · Granted Tue May 04 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Apr 29 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  8. US 10993959

    Methods and compositions for increasing the suppressive function of regulatory T-cells (Tregs)

    Regents of the University of Minnesota · Granted Tue May 04 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Apr 29 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  9. US 10993948

    RNA polymerase I inhibitors and uses thereof

    TEL HASHOMER MEDICAL RESEARCH INFRASTRUCTURE AND SERVICES LTD. · Granted Tue May 04 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Apr 29 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  10. US 10993936

    Method of treating one or more symptoms of pulmonary fibrosis by administering inhibitors of nicotinamide phosphoribotransferase

    Arizona Board of Regents on Behalf of the University of Arizona · Granted Tue May 04 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Apr 29 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  11. US 10993419

    Genetically modified cells, tissues, and organs for treating disease

    Regents of the University of Minnesota · Granted Tue May 04 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Apr 29 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  12. US 10993983

    Cyclic peptide epitopes and small-molecule mimics for inducing autophagy

    The Board of Regents of the University of Texas System · Granted Tue May 04 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Apr 29 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  13. US 10994016

    Graphene oxide mediated cellular delivery of gadolinium-labeled molecules

    Northwestern University · Granted Tue May 04 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Apr 29 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  14. US 10993999

    Materials and methods for producing improved lentiviral vector particles

    IMMUNE DESIGN CORP. · Granted Tue May 04 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Apr 29 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  15. US 10993967

    Combinatorial cancer immunotherapy

    Senti Biosciences, Inc. · Granted Tue May 04 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Apr 29 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  16. US 10995317

    NK cells exhibiting an adaptive phenotype and methods for preparing and for using

    Regents of the University of Minnesota · Granted Tue May 04 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Apr 29 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  17. US 10995089

    Zaindole derivatives and their use as ERK kinase inhibitors

    AGV Discovery · Granted Tue May 04 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Apr 29 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  18. US 10994019

    Bicyclic peptide-toxin conjugates specific for MT1-MMP

    BicycleRD Limited · Granted Tue May 04 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Apr 29 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  19. US 10995336

    Serpina1 iRNA compositions and methods of use thereof

    Alnylam Pharmaceuticals, Inc. · Granted Tue May 04 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Apr 29 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  20. US 2021128573

    DOSING REGIMENS FOR USE IN TREATING MYELOFIBROSIS AND MPN-RELATED DISORDERS WITH NAVITOCLAX

    ABBVIE INC [US] · Granted Thu May 06 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Wed May 01 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  21. US 11000520

    Buprenorphine dosing regimens

    Indivior UK Limited · Granted Tue May 11 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 06 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  22. US 11000568

    Means and methods for treating copper-related diseases

    THE REGENTS OF THE UNIVERSITY OF MICHIGAN · Granted Tue May 11 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 06 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  23. US 11000493

    Solid solution compositions and use in chronic inflammation

    Infirst Healthcare Limited · Granted Tue May 11 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 06 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  24. US 11000517

    Dosage and formulation

    Almirall, S.A. · Granted Tue May 11 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 06 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  25. US 11000595

    Modulators of PCSK9 expression

    Ionis Pharmaceuticals, Inc. · Granted Tue May 11 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 06 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  26. US 11000599

    Peptidic self-assembly for nucleic acid delivery

    S. M. DISCOVERY GROUP INC. · Granted Tue May 11 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 06 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  27. US 11000600

    Exon skipping oligomer conjugates for muscular dystrophy

    Sarepta Therapeutics, Inc. · Granted Tue May 11 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 06 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  28. US 11000711

    Compositions for forming films having a desired degree of obscuration and methods of making and using the same

    W.R. Grace & Co.-Conn. · Granted Tue May 11 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 06 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  29. US 11000562

    Use of isolated fractions of mastic gum for treating optic neuropathy

    REGENERA PHARMA LTD. · Granted Tue May 11 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 06 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  30. US 11000561

    Adeno-associated virus purification methods

    Takeda Pharmaceutical Company Limited · Granted Tue May 11 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 06 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  31. US 11000593

    Cellular or viral membrane coated nanostructures and uses thereof

    The Regents of the University of California · Granted Tue May 11 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 06 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  32. US 11001578

    N-((HET)arylmethyl)-heteroaryl-carboxamides compounds as plasma kallikrein inhibitors

    KalVista Pharmaceuticals Limited · Granted Tue May 11 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 06 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  33. US 11001564

    Substituted chromane-8-carboxamide compounds and analogues thereof, and methods using same

    ARBUTUS BIOPHARMA CORPORATION · Granted Tue May 11 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 06 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  34. US 11000602

    Delivery of small interfering RNA and micro RNA through nanogels containing hydrophobic pseudo-peptides

    The Board of Regents of the University of Texas System · Granted Tue May 11 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 06 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  35. US 11001641

    Monoclonal antibody therapy for pancreas cancer

    PRECISION BIOLOGICS, INC. · Granted Tue May 11 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 06 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  36. US 11001594

    Heterocyclic modulators of HIF activity for treatment of disease

    The Board of Regents of the University of Texas System · Granted Tue May 11 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 06 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  37. US 11001551

    Controlled release pharmaceutical formulations

    United Therapeutics Corporation · Granted Tue May 11 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 06 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  38. US 11000579

    Recombinant Eimeria maxima protein delivered as nanoparticles

    The United States of America, as represented by the Secretary of Agriculture · Granted Tue May 11 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 06 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  39. US 11000513

    Anhydrous compositions of mTOR inhibitors and methods of use

    PALVELLA THERAPEUTICS, INC. · Granted Tue May 11 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 06 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  40. US 11000481

    Composite preparation of mosapride and rabeprazole

    KOREA UNITED PHARM. INC. · Granted Tue May 11 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 06 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  41. US 11001820

    Delivery of therapeutic agents by a collagen binding protein

    Montefiore Medical Center · Granted Tue May 11 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 06 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  42. US 11001627

    Correctly folded etanercept in high purity and excellent yield

    Coherus BioSciences, Inc. · Granted Tue May 11 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 06 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  43. US 11000409

    Devices and methods for slurry generation

    MIRAKI INNOVATION THINK TANK LLC · Granted Tue May 11 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 06 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  44. US 11000570

    Isoform Nell-1 peptide

    The Regents of the University of California · Granted Tue May 11 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 06 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  45. US 11000502

    Antimicrobial compositions comprising copper-hydroxypyrone complexes

    United Kingdom Research and Innovation · Granted Tue May 11 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 06 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  46. US 11000576

    Enzymes and methods for cleaving n-glycans from glycoproteins

    The Regents of the University of California · Granted Tue May 11 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 06 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  47. US 11000588

    Etanercept formulations stabilized with sodium chloride

    Coherus BioSciences, Inc. · Granted Tue May 11 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 06 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  48. US 11001592

    DNA polymerase IIIC inhibitors and use thereof

    Acurx Pharmaceuticals, Inc. · Granted Tue May 11 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 06 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

Frequently asked questions

How many pharma patents expire in 2041?

2,000 published patents in our USPTO index have expiration dates falling in calendar year 2041.