Wednesday, June 10, 2026

Intelligence · Patents

Patents expiring in 2040

Annual patent cliff calendar for 2040 — US pharmaceutical patents by expiration date.

Patents
1,866

Quick answer

1,866 indexed pharmaceutical patents have expiration dates in 2040. Browse by soonest expiry with links to assignee companies and related drugs.

  1. US 10548953

    Factor VIII-XTEN fusions and uses thereof

    BIOVERATIV THERAPEUTICS INC. · Granted Tue Feb 04 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 30 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  2. US 10548890

    Parenteral formulations of lipophilic pharmaceutical agents and methods for preparing and using the same

    Platform Brightworks Two, Ltd. · Granted Tue Feb 04 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 30 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  3. US 10548886

    Methods of treatment using a JAK inhibitor compound

    Theravance Biopharma R&D IP, LLC · Granted Tue Feb 04 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 30 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  4. US 10548946

    Therapeutic compositions for neutralizing type I interferons, and methods of use

    The Government of the United States, as represented by the Secretary of the Army · Granted Tue Feb 04 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 30 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  5. US 10548962

    Use of the salmonella SPP type III secretion proteins as a protective vaccination

    The Board of Regents for Oklahoma State University · Granted Tue Feb 04 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 30 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  6. US 10548850

    Therapeutic composition comprising insulin prepared for delivery into an intestinal tract

    Rani Therapeutics, LLC · Granted Tue Feb 04 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 30 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  7. US 10548883

    Benzotriazole-derived α and β-unsaturated amide compound used as TGF-β RI inhibitor

    Medshine Discovery Inc. · Granted Tue Feb 04 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 30 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  8. US 10550084

    Substituted 1-hydroxy-pyridin-2(1H)-ones, and methods of making and using same

    ARBUTUS BIOPHARMA CORPORATION · Granted Tue Feb 04 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 30 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  9. US 10548899

    Quinazolinone and benzotriazinone compounds with cholinergic muscarinin M1 receptor positive allosteric modulator activity

    Takeda Pharmaceutical Company Limited · Granted Tue Feb 04 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 30 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  10. US 10548860

    HIF-1 modulator paint formulation and uses thereof

    United States Government as represented by the Department of Veterans Affairs · Granted Tue Feb 04 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 30 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  11. US 10550081

    Crystalline freebase forms of a biphenyl compound

    Theravance Biopharma R&D IP, LLC · Granted Tue Feb 04 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 30 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  12. US 10548984

    RVG Derived peptides

    UNITED ARAB EMIRATES UNIVERSITY · Granted Tue Feb 04 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 30 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  13. US 10548954

    Factor IX polypeptides and methods of use thereof

    BIOVERATIV THERAPEUTICS INC. · Granted Tue Feb 04 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 30 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  14. US 10548971

    MERS-CoV vaccine

    Inovio Pharmaceuticals, Inc. · Granted Tue Feb 04 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 30 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  15. US 10548979

    Light-activated compositions and methods using the same

    The Regents of the University of Colorado, a Body Corporate · Granted Tue Feb 04 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 30 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  16. US 10548302

    Fibrillin-1 mutations for modeling neonatal progeroid syndrome with congenital lipodystrophy

    REGENERON PHARMACEUTICALS, INC. · Granted Tue Feb 04 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 30 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  17. US 10548905

    Amorphous onapristone compositions and methods of making the same

    CONTEXT BIOPHARMA, INC. · Granted Tue Feb 04 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 30 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  18. US 10550129

    1-arylcarbonyl-4-oxy-piperidine compounds useful for the treatment of neurodegenerative diseases

    Takeda Pharmaceutical Company Limited · Granted Tue Feb 04 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 30 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  19. US 10550118

    JAK inhibitors containing a 4-membered heterocyclic amide

    Theravance Biopharma R&D IP, LLC · Granted Tue Feb 04 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 30 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  20. US 10550163

    Peptide fragments of netrin-1 and compositions and methods thereof

    The Regents of the University of California · Granted Tue Feb 04 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 30 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  21. US 10550157

    Compositions and methods for treating central nervous system (CNS) disorders and mood disorders

    Arizona Board of Regents on Behalf of the University of Arizona · Granted Tue Feb 04 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 30 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  22. US 10550192

    Antigen-binding proteins that antagonize leptin receptor

    REGENERON PHARMACEUTICALS, INC. · Granted Tue Feb 04 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 30 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  23. US 2020040086

    PHARMACEUTICAL COMBINATIONS COMPRISING AN ANTI-LY75 ANTIBODY

    BERLIN CHEMIE AG [DE] · Granted Thu Feb 06 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Wed Feb 01 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  24. CA 3103888

    PROCEDE DE PURIFICATION DE SULFATE D'ISAVUCONAZONIUM

    BASILEA PHARM INT AG [CH] · Granted Thu Feb 06 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Wed Feb 01 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  25. US 10555929

    Methods for the treatment of nonalcoholic fatty liver disease and/or lipodystrophy

    Coherus BioSciences, Inc. · Granted Tue Feb 11 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 06 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  26. US 10555961

    Materials and methods for treating bacterial infections using C-1 gentamicin

    United States Government as represented by the Department of Veterans Affairs · Granted Tue Feb 11 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 06 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  27. US 10556890

    Heteroaryl compounds and methods of use thereof

    PGI Drug Discovery LLC · Granted Tue Feb 11 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 06 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  28. US 10556021

    Nanocarriers for drug delivery

    The Regents of the University of California · Granted Tue Feb 11 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 06 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  29. US 10556897

    Protein kinase inhibitors

    Princeton Drug Discovery, Inc · Granted Tue Feb 11 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 06 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  30. US 10555964

    Composition and method for promoting reduction of heat stress in animals

    Arizona Board of Regents on Behalf of the University of Arizona · Granted Tue Feb 11 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 06 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  31. US 10556875

    Bis-diazeniumdiolate compounds as anti-cancer agents

    ARIZONA BOARD OF REGENTS FOR AND ON BEHALF OF ARIZONA STATE UNIVERSITY · Granted Tue Feb 11 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 06 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  32. US 10555928

    Cannabis extracts and methods of preparing and using same

    United Cannabis Corp. · Granted Tue Feb 11 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 06 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  33. US 10556916

    Zirconium-89 oxine complex as a cell labeling agent for positron emission tomography

    The United States of America, as represented by the Secretary, Department of Health and Human Services · Granted Tue Feb 11 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 06 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  34. US 10556861

    Ionizable cationic lipid for RNA delivery

    ARCTURUS THERAPEUTICS, INC. · Granted Tue Feb 11 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 06 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  35. US 10556256

    Antibacterial water

    Takeda Pharmaceutical Company Limited · Granted Tue Feb 11 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 06 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  36. US 10556881

    Nrf2 activating compounds and uses thereof

    Rigel Pharmaceuticals, Inc. · Granted Tue Feb 11 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 06 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  37. US 10555963

    Klotho protein and related compounds for the treatment and diagnosis of cancer

    TEL HASHOMER MEDICAL RESEARCH INFRASTRUCTURE AND SERVICES LTD. · Granted Tue Feb 11 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 06 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  38. US 10556001

    Thermal inactivation of rotavirus

    The United States of America, as represented by the Secretary, Department of Health and Human Services · Granted Tue Feb 11 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 06 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  39. US 10556860

    hTERT modulators and methods of use

    THE ARIZONA BOARD OF REGENTS · Granted Tue Feb 11 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 06 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  40. US 10556891

    Compositions and methods for inhibition of the JAK pathway

    Rigel Pharmaceuticals, Inc. · Granted Tue Feb 11 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 06 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  41. US 10557137

    Modulating apolipoprotein (a) expression

    Ionis Pharmaceuticals, Inc. · Granted Tue Feb 11 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 06 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  42. US 10557118

    Compositions and methods for prevention or treatment of neoplastic disease in a mammalian subject

    The Government of the United States of American, as represented by the Secretary, Department of Health and Human Services · Granted Tue Feb 11 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 06 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  43. US 10556940

    T cell receptors recognizing HLA-Cw8 restricted mutated KRAS

    The United States of America, as represented by the Secretary, Department of Health and Human Services · Granted Tue Feb 11 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 06 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  44. US 10556892

    Piperazinyl methanone NAAA inhibitors

    The Regents of the University of California · Granted Tue Feb 11 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 06 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  45. US 10555997

    Antigens and vaccines directed against human enteroviruses

    SENTINEXT THERAPEUTICS Sdn Bhd · Granted Tue Feb 11 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 06 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  46. US 10555942

    Emetine compounds for treatment and prevention of flavivirus infection

    The United States of America, as represented by the Secretary, Department of Health and Human Services · Granted Tue Feb 11 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 06 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  47. US 10555960

    Use of an aminoglycoside for nonsense mutation suppression and the treatment of disease

    PTC THERAPEUTICS, INC. · Granted Tue Feb 11 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 06 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  48. US 10556945

    Antagonist antibodies directed against calcitonin gene-related peptide and methods using same

    TEVA PHARMACEUTICALS INTERNATIONAL GMBH · Granted Tue Feb 11 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 06 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

Frequently asked questions

How many pharma patents expire in 2040?

1,866 published patents in our USPTO index have expiration dates falling in calendar year 2040.