Wednesday, June 10, 2026

Intelligence · Patents

Patents expiring in 2040

Annual patent cliff calendar for 2040 — US pharmaceutical patents by expiration date.

Patents
1,866

Quick answer

1,866 indexed pharmaceutical patents have expiration dates in 2040. Browse by soonest expiry with links to assignee companies and related drugs.

  1. US 10543257

    Lentiviral vector for treating hemoglobin disorders

    The United States of America, as represented by the Secretary, Department of Health and Human Services · Granted Tue Jan 28 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 23 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  2. US 10544126

    Sulfonyl piperidine derivatives and their use for treating prokineticin mediated diseases

    Takeda Pharmaceutical Company Limited · Granted Tue Jan 28 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 23 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  3. US 10544145

    P2X3 and/or P2X2/3 compounds and methods

    Asana BioSciences, LLC · Granted Tue Jan 28 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 23 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  4. US 10544467

    Solid tumor methylation markers and uses thereof

    The Regents of the University of California · Granted Tue Jan 28 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 23 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  5. US 10543192

    Glycopyrrolate salts

    Dermira, Inc. · Granted Tue Jan 28 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 23 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  6. US 10543181

    Toxic aldehyde related diseases and treatment

    Aldeyra Therapeutics, Inc. · Granted Tue Jan 28 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 23 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  7. US 10544199

    Interferon alpha 2B variants

    TEVA PHARMACEUTICALS AUSTRALIA PTY LTD · Granted Tue Jan 28 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 23 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  8. US 10543221

    Beta-lactamase inhibitors, formulations, and uses thereof

    The Regents of the University of California · Granted Tue Jan 28 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 23 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  9. US 10544232

    Methods for treating patients with heterozygous familial hypercholesterolemia (heFH) with an anti-PCSK9 antibody

    REGENERON PHARMACEUTICALS, INC. · Granted Tue Jan 28 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 23 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  10. US 10543481

    Targeted, metal-catalyzed fluorination of complex compounds with fluoride ion via decarboxylation

    THE TRUSTEES OF PRINCETON UNIVERSITY · Granted Tue Jan 28 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 23 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  11. US 10544113

    Thiazolidinone compounds and use thereof

    Regents of the University of Minnesota · Granted Tue Jan 28 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 23 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  12. US 10544085

    Oils having antibacterial activity

    The United States of America, as represented by the Secretary of Agriculture · Granted Tue Jan 28 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 23 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  13. US 10544111

    Heterocyclic compound

    Takeda Pharmaceutical Company Limited · Granted Tue Jan 28 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 23 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  14. US 10543280

    Stabilization of biomolecules using sugar polymers

    The Regents of the University of California · Granted Tue Jan 28 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 23 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  15. US 10543282

    Targeted peptide conjugates

    Marker Gene Technologies, Inc · Granted Tue Jan 28 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 23 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  16. US 10543283

    Intranasal administration of guanidinylated aminoglycosides

    The Regents of the University of California · Granted Tue Jan 28 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 23 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  17. US 10544223

    Combination therapy with an anti-axl antibody-drug conjugate

    ADC THERAPEUTICS SA · Granted Tue Jan 28 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 23 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  18. US 10544392

    Methods of isolating T cells and T cell receptors having antigenic specificity for a cancer-specific mutation from peripheral blood

    The United States of America, as represented by the Secretary, Department of Health and Human Services · Granted Tue Jan 28 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 23 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  19. US 10543268

    Genetically engineered swine influenza virus and uses thereof

    The United States of America, as represented by the Secretary of Agriculture · Granted Tue Jan 28 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 23 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  20. US 10543337

    Nitric oxide delivery devices

    THE REGENTS OF THE UNIVERSITY OF MICHIGAN · Granted Tue Jan 28 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 23 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  21. US 10544406

    Characterization of four prophage endolysins specific for clostridium perfringens

    The United States of America, as represented by the Secretary of Agriculture · Granted Tue Jan 28 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 23 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  22. US 10544108

    Hydrazide containing nuclear transport modulators and uses thereof

    Karyopharm Therapeutics Inc. · Granted Tue Jan 28 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 23 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  23. US 10543222

    Therapy for inhibition of single-stranded RNA virus replication

    RedHill Biopharma Ltd. · Granted Tue Jan 28 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 23 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  24. US 10544418

    RNAi inhibition of alpha-ENaC expression

    Arrowhead Pharmaceuticals, Inc. · Granted Tue Jan 28 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 23 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  25. US 10544188

    Inhibitor of apoptosis protein (IAP) antagonists

    SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE · Granted Tue Jan 28 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 23 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  26. US 2020030466

    Stable, concentrated radionuclide complex solutions

    ADVANCED ACCELERATOR APPLICATIONS ITALY SRL [IT] · Granted Thu Jan 30 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Wed Jan 25 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  27. US 2020030465

    Stable, concentrated radionuclide complex solutions

    ADVANCED ACCELERATOR APPLICATIONS ITALY SRL [IT] · Granted Thu Jan 30 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Wed Jan 25 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  28. US 10548863

    Process to prepare treprostinil, the active ingredient in Remodulin®

    United Therapeutics Corporation · Granted Tue Feb 04 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 30 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  29. US 10550407

    Methods and compositions for RNA-directed target DNA modification and for RNA-directed modulation of transcription

    The Regents of the University of California · Granted Tue Feb 04 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 30 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  30. US 10550386

    Monomers and oligonucleotides comprising cycloaddition adduct(s)

    Alnylam Pharmaceuticals, Inc. · Granted Tue Feb 04 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 30 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  31. US 10548850

    Therapeutic composition comprising insulin prepared for delivery into an intestinal tract

    Rani Therapeutics, LLC · Granted Tue Feb 04 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 30 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  32. US 10550164

    Brachyury deletion mutants, non-yeast vectors encoding Brachyury deletion mutants, and their use

    The United States of America, as represented by the Secretary, Department of Health and Human Services · Granted Tue Feb 04 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 30 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  33. US 10548879

    (2R,4R)-5-(5′-chloro-2′-fluorobiphenyl-4-yl)-2-hydroxy-4-[(5-methyloxazole-2-carbonyl)amino]pentanoic acid

    Theravance Biopharma R&D IP, LLC · Granted Tue Feb 04 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 30 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  34. US 10548875

    Glycopyrrolate salts

    Dermira, Inc. · Granted Tue Feb 04 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 30 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  35. US 10553318

    Individual and cohort pharmacological phenotype prediction platform

    THE REGENTS OF THE UNIVERSITY OF MICHIGAN · Granted Tue Feb 04 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 30 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  36. US 10548987

    Antibody-drug conjugates for targeting CD56-positive tumors

    The United States of America, as represented by the Secretary, Department of Health and Human Services · Granted Tue Feb 04 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 30 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  37. US 10550156

    Ang (1-7) derivative oligopeptides and methods for using and producing the same

    Arizona Board of Regents on Behalf of the University of Arizona · Granted Tue Feb 04 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 30 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  38. US 10548856

    Compounds and methods for modulating serotonin receptors in the periphery

    Northwestern University · Granted Tue Feb 04 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 30 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  39. US 10548970

    Human rotavirus G9P[6] strain and use as a vaccine

    The United States of America, as represented by the Secretary, Department of Health and Human Services · Granted Tue Feb 04 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 30 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  40. US 10548964

    Antigens and vaccines directed against human enteroviruses

    SENTINEXT THERAPEUTICS Sdn Bhd · Granted Tue Feb 04 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 30 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  41. US 10548890

    Parenteral formulations of lipophilic pharmaceutical agents and methods for preparing and using the same

    Platform Brightworks Two, Ltd. · Granted Tue Feb 04 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 30 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  42. US 10548886

    Methods of treatment using a JAK inhibitor compound

    Theravance Biopharma R&D IP, LLC · Granted Tue Feb 04 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 30 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  43. US 10548883

    Benzotriazole-derived α and β-unsaturated amide compound used as TGF-β RI inhibitor

    Medshine Discovery Inc. · Granted Tue Feb 04 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 30 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  44. US 10548860

    HIF-1 modulator paint formulation and uses thereof

    United States Government as represented by the Department of Veterans Affairs · Granted Tue Feb 04 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 30 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  45. US 10548302

    Fibrillin-1 mutations for modeling neonatal progeroid syndrome with congenital lipodystrophy

    REGENERON PHARMACEUTICALS, INC. · Granted Tue Feb 04 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 30 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  46. US 10548889

    Compositions of CXCR4 inhibitors and methods of preparation and use

    X4 Pharmaceuticals, Inc. · Granted Tue Feb 04 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 30 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  47. US 10548877

    Aromatic ring compound

    Takeda Pharmaceutical Company Limited · Granted Tue Feb 04 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 30 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  48. US 10548948

    Methods of treating fungal infections

    United States of America as represented by the Secretary of the Air Force · Granted Tue Feb 04 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 30 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

Frequently asked questions

How many pharma patents expire in 2040?

1,866 published patents in our USPTO index have expiration dates falling in calendar year 2040.