Wednesday, June 10, 2026
🇺🇸 FDA

Intelligence · Patents

Patents expiring in 2039

Annual patent cliff calendar for 2039 — US pharmaceutical patents by expiration date.

Patents
1,782

Quick answer

1,782 indexed pharmaceutical patents have expiration dates in 2039. Browse by soonest expiry with links to assignee companies and related drugs.

  1. US 10501516

    Peptide compound

    Takeda Pharmaceutical Company Limited · Granted Tue Dec 10 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 05 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  2. US 10501507

    Griffithsin mutants

    The United States of America, as represented by the Secretary, Department of Health and Human Services · Granted Tue Dec 10 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 05 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  3. US 10500290

    Peptide reagents and methods for detection and targeting of dysplasia, early cancer and cancer

    THE REGENTS OF THE UNIVERSITY OF MICHIGAN · Granted Tue Dec 10 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 05 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  4. US 10501500

    Methods of detection and removal of rhabdoviruses from cell lines

    Takeda Vaccines, Inc. · Granted Tue Dec 10 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 05 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  5. US 10501490

    Taccalonolide microtubule stabilizers

    The Board of Regents of the University of Texas System · Granted Tue Dec 10 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 05 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  6. US 10501504

    Adhesin as immunogen against enterotoxigenic Escherichia coli

    United States of America as represented by the Secretary of the Air Force · Granted Tue Dec 10 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 05 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  7. US 10501470

    Use of asarinin in preparation of medicines for treating various coughs

    THE FIRST AFFILIATED HOSPITAL OF GUANGZHOU MEDICAL UNIVERSITY · Granted Tue Dec 10 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 05 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  8. US 10501482

    Compounds for treating spinal muscular atrophy

    PTC THERAPEUTICS, INC. · Granted Tue Dec 10 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 05 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  9. US 10501439

    DNA-PK inhibitors

    Vertex Pharmaceuticals Incorporated · Granted Tue Dec 10 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 05 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  10. US 10501428

    Thymoquinone derivatives for treatment of cancer

    UNITED ARAB EMIRATES UNIVERSITY · Granted Tue Dec 10 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 05 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  11. US 10500281

    Injectable long-acting local anesthetic semi-solid formulations and its compositions

    MIRA PHARMA CORPORATION · Granted Tue Dec 10 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 05 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  12. US 10501435

    Substituted quinazoline compounds and uses thereof for modulating glucocerebrosidase activity

    Northwestern University · Granted Tue Dec 10 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 05 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  13. US 10501558

    Modified Fc proteins comprising site-specific non-natural amino acid residues, conjugates of the same, methods of their preparation and methods of their use

    Sutro Biopharma, Inc. · Granted Tue Dec 10 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 05 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  14. EP 3576795

    ORALES SCHILDDRÜSENTHERAPEUTIKUM

    BERLIN CHEMIE AG [DE] · Granted Wed Dec 11 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Tue Dec 06 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  15. US 2019374520

    TREATMENT OF MIGRAINE

    ALLERGAN PHARMACEUTICALS INT LTD [IE] · Granted Thu Dec 12 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Wed Dec 07 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  16. US 2019374518

    TREATMENT OF MIGRAINE

    ALLERGAN PHARMACEUTICALS INT LTD [IE] · Granted Thu Dec 12 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Wed Dec 07 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  17. US 10508140

    Peptide having hair growth-promoting activity and/or melanin generation-promoting activity, and use thereof

    CAREGEN CO., LTD. · Granted Tue Dec 17 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 12 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  18. US 10508129

    Pharmaceutical targeting of a mammalian cyclic di-nucleotide signaling pathway

    The Board of Regents of the University of Texas System · Granted Tue Dec 17 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 12 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  19. US 10507284

    Daily periodic target-zone modulation in the model predictive control problem for artificial pancreas for type I diabetes applications

    The Regents of the University of California · Granted Tue Dec 17 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 12 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  20. US 10507211

    Treatment for hereditary neuropathy with liability to pressure palsies (HNPP)

    THE UNITED STATES AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS · Granted Tue Dec 17 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 12 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  21. US 10507225

    Powder for regulating intestinal flora and protecting gastric mucosa, preparation method and use thereof

    INFINITUS (CHINA) COMPANY LTD. · Granted Tue Dec 17 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 12 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  22. US 10508103

    Benzimidazole-linked indole compound acting as novel divalent IAP antagonist

    Medshine Discovery Inc. · Granted Tue Dec 17 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 12 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  23. US 10508106

    Bicyclic BET bromodomain inhibitors and uses thereof

    The United States of America, as represented by the Secretary, Department of Health and Human Services · Granted Tue Dec 17 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 12 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  24. US 10508307

    Methods of diagnosing chronic obstructive pulmonary disease (COPD) using novel molecular biomarkers

    Transgenion—International Institute for Regenerative Translational Medicine GmbH · Granted Tue Dec 17 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 12 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  25. US 10508083

    Substituted piperidine compound and use thereof

    Takeda Pharmaceutical Company Limited · Granted Tue Dec 17 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 12 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  26. US 10507237

    Attenuated African swine fever virus vaccine

    The Pirbright Institute · Granted Tue Dec 17 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 12 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  27. US 10507239

    V1/V2 fragments of a HIV-1 envelope glycoprotein

    The Regents of the University of California · Granted Tue Dec 17 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 12 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  28. US 10507187

    Regenerative tissue grafts and methods of making same

    The Government of the United States of America as represented by the Secretary of the Deptartment of Health and Human Services · Granted Tue Dec 17 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 12 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  29. US 10508122

    Heterocyclic hydroxamic acids as protein deacetylase inhibitors and dual protein deacetylase-protein kinase inhibitors and methods of use thereof

    The Regents of the University of Colorado, a Body Corporate · Granted Tue Dec 17 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 12 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  30. US 10508136

    Peptides and compositions for prevention of cell adhesion and methods of using same

    TEL HASHOMER MEDICAL RESEARCH INFRASTRUCTURE AND SERVICES LTD. · Granted Tue Dec 17 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 12 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  31. US 10508134

    Peptide compositions and methods of use

    THE REGENTS OF THE UNIVERSITY OF MICHIGAN · Granted Tue Dec 17 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 12 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  32. CA 3102476

    ASSOCIATIONS PHARMACEUTIQUES

    BERLIN CHEMIE AG [DE] · Granted Thu Dec 19 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Wed Dec 14 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  33. US 10512609

    Formulations of (R)-2-amino-3-phenylpropyl carbamate

    Jazz Pharmaceuticals Ireland Limited · Granted Tue Dec 24 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 19 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  34. US 10512669

    Blockade of inflammatory proteases with cyclic peptides

    The Regents of the University of California · Granted Tue Dec 24 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 19 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  35. US 10512691

    Systems and methods for targeted imaging and ablation of cardiac cells

    THE REGENTS OF THE UNIVERSITY OF MICHIGAN · Granted Tue Dec 24 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 19 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  36. US 10513532

    Compound containing dexpanthenol

    Julius-Maximilians-Universitat Wurzburg · Granted Tue Dec 24 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 19 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  37. US 10513543

    Antigen chimera, antigen composition, vaccine, method of preparing the same and cassette thereof

    SHANGHAI UNITED CELL BIOTECHNOLOGY CO., LTD. · Granted Tue Dec 24 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 19 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  38. US 10513558

    Anti-PD1 antibodies, activatable anti-PD1 antibodies, and methods of use thereof

    CytomX Therapeutics, Inc. · Granted Tue Dec 24 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 19 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  39. US 10513712

    Methods and compositions for RNA-directed target DNA modification and for RNA-directed modulation of transcription

    The Regents of the University of California · Granted Tue Dec 24 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 19 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  40. US 10513703

    Hepatitis B virus (HBV) iRNA compositions and methods of use thereof

    Alnylam Pharmaceuticals, Inc. · Granted Tue Dec 24 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 19 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  41. US 10513587

    Self-integrating hydrogels and methods for making the same

    THE REGENTS OF THE UNIVERSITY OF MICHIGAN · Granted Tue Dec 24 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 19 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  42. US 10513557

    Anti-ASIC1 antibodies and uses thereof

    REGENERON PHARMACEUTICALS, INC. · Granted Tue Dec 24 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 19 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  43. US 10513542

    Minicircle DNA vector vaccine platform for foot-and-mouth disease and methods thereof

    The Government of the United States of America, as represented by the Secretary of Homeland Security · Granted Tue Dec 24 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 19 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  44. US 10513549

    Cleavage-activatable interferon-alpha proprotein

    CytomX Therapeutics, Inc. · Granted Tue Dec 24 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 19 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  45. US 10513533

    Tunicamycin related compounds with anti-bacterial activity

    The United States of America, as represented by the Secretary of Agriculture · Granted Tue Dec 24 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 19 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  46. US 10513526

    Solid state forms of spiro-oxindole compounds

    Xenon Pharmaceuticals Inc. · Granted Tue Dec 24 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 19 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  47. US 10513521

    Compositions and methods for inhibiting BMP

    The United States of America, as represented by the Secretary, Department of Health and Human Services · Granted Tue Dec 24 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 19 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  48. US 10512687

    Compositions and methods for enhanced innate immunity

    The Regents of the University of Colorado, a Body Corporate · Granted Tue Dec 24 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 19 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

Frequently asked questions

How many pharma patents expire in 2039?

1,782 published patents in our USPTO index have expiration dates falling in calendar year 2039.

Drug approvals, clinical trials, M&A, event intelligence, and company updates — weekly.

Customize topics & region
Topics
Region

No spam. Unsubscribe anytime. See our privacy policy.