Wednesday, June 10, 2026

Intelligence · Patents

Patents expiring in 2039

Annual patent cliff calendar for 2039 — US pharmaceutical patents by expiration date.

Patents
1,782

Quick answer

1,782 indexed pharmaceutical patents have expiration dates in 2039. Browse by soonest expiry with links to assignee companies and related drugs.

  1. US 10493057

    Acetogenin molecules having antiplatelet and/or antithrombic activities, and methods and compositions thereof

    INSTITUTO TECNOLÓGICO Y DE ESTUDIOS SUPERIORES DE MONTERREY · Granted Tue Dec 03 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 28 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  2. US 10493066

    Fumarate analogs and uses thereof

    Rigel Pharmaceuticals, Inc. · Granted Tue Dec 03 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 28 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  3. US 10493069

    Methods of treating behavioral syndromes using pipradrol

    OVID THERAPEUTICS INC. · Granted Tue Dec 03 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 28 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  4. US 10493065

    Formulations and methods of manufacturing formulations for use in colonic evacuation

    RedHill Biopharma Ltd. · Granted Tue Dec 03 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 28 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  5. US 10493103

    Peroxide formulations and methods and applicators for using the same

    Aclaris Therapeutics, Inc. · Granted Tue Dec 03 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 28 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  6. US 10493098

    Mesoporous silica-coated nanoparticles

    Regents of the University of Minnesota · Granted Tue Dec 03 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 28 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  7. US 10493092

    Antisense compounds

    Ionis Pharmaceuticals, Inc. · Granted Tue Dec 03 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 28 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  8. US 10493149

    Stable anti-OSMR antibody formulation

    Kiniksa Pharmaceuticals, GmbH · Granted Tue Dec 03 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 28 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  9. US 10493151

    Etanercept formulations stabilized with sodium chloride

    Coherus BioSciences, Inc. · Granted Tue Dec 03 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 28 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  10. US 10493162

    Somatostatin receptor-based cancer therapy

    The Board of Regents of the University of Texas System · Granted Tue Dec 03 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 28 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  11. US 10494316

    Process for the preparation of deuterated ethanol from D2O

    Deuteria Beverages, LLC · Granted Tue Dec 03 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 28 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  12. US 10494683

    Nitrate- and nitrite-reducing probiotic feed additive

    The United States of America, as represented by the Secretary of Agriculture · Granted Tue Dec 03 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 28 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  13. US 10494347

    Processes for the preparation of uracil derivatives

    Neurocrine Biosciences, Inc. · Granted Tue Dec 03 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 28 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  14. US 10494382

    Crystalline solvate comprising 3-((1R,3s,5S)-3-((7-((5-methyl-1H-pyrazol-3-yl)amino)-1,6-naphthyridin-5-yl)amino-8-azabicyclo[3.2.1]octan-8-yl)propanenitrile, methanol, N-N-dimethylformamide, and water

    Theravance Biopharma R&D IP, LLC · Granted Tue Dec 03 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 28 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  15. US 10494402

    Peptides that stimulate subcutaneous adipogenesis

    The Regents of the University of California · Granted Tue Dec 03 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 28 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  16. US 10500261

    Synthetic antigen constructs against campylobacter jejuni

    United States of America as represented by the Secretary of the Air Force · Granted Tue Dec 10 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 05 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  17. US 10499682

    Micronutrient formulation in electronic cigarettes

    New Age Beverage Corporation · Granted Tue Dec 10 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 05 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  18. US 10500194

    Covalent small molecule DCN1 inhibitors and therapeutic methods using the same

    THE REGENTS OF THE UNIVERSITY OF MICHIGAN · Granted Tue Dec 10 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 05 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  19. US 10500264

    Development of mutations useful for attenuating dengue viruses and chimeric dengue viruses

    The United States of America, as represented by the Secretary, Department of Health and Human Services · Granted Tue Dec 10 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 05 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  20. US 10500277

    Combination tumor treatment with drug-loaded, bispecific ligand-targeted minicells and interferon-gamma

    EnGeneIC Molecular Delivery Pty Ltd · Granted Tue Dec 10 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 05 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  21. US 10500284

    Pharmaceutical formulation

    Semnur Pharmaceuticals, Inc. · Granted Tue Dec 10 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 05 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  22. US 10501444

    Inhibitors of influenza virus replication, application methods and uses thereof

    SUNSHINE LAKE PHARMA CO., LTD. · Granted Tue Dec 10 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 05 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  23. US 10501511

    Low molecular polypeptide for preventing and treating inflammation and use thereof

    SHANGHAI FIRST PEOPLE'S HOSPITAL · Granted Tue Dec 10 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 05 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  24. US 10501558

    Modified Fc proteins comprising site-specific non-natural amino acid residues, conjugates of the same, methods of their preparation and methods of their use

    Sutro Biopharma, Inc. · Granted Tue Dec 10 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 05 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  25. US 10500167

    Droplet-embedded microfibers, and methods and devices for preparing and using same

    THE TRUSTEES OF PRINCETON UNIVERSITY · Granted Tue Dec 10 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 05 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  26. US 10500156

    Multi-compartmental macrophage delivery

    Northwestern University · Granted Tue Dec 10 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 05 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  27. US 10500177

    Glutarate compounds for treating ischemia-reperfusion injuries

    The Regents of the University of California · Granted Tue Dec 10 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 05 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  28. US 10500175

    Compositions and methods for the treatment of cancer

    KoDiscovery, LLC · Granted Tue Dec 10 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 05 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  29. US 10500238

    Use of gram negative species to treat atopic dermatitis

    The United States of America, as represented by the Secretary, Department of Health and Human Services · Granted Tue Dec 10 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 05 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  30. US 10500208

    Emulsion formulations of aprepitant

    Heron Therapeutics, Inc. · Granted Tue Dec 10 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 05 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  31. US 10500216

    Optimizing mifepristone absorption

    Corcept Therapeutics Incorporated · Granted Tue Dec 10 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 05 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  32. US 10500218

    Uptake of pharmaceuticals within cyclodextrin-based porous materials

    Northwestern University · Granted Tue Dec 10 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 05 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  33. US 10500229

    Targeted disruption of the MHC cell receptor

    Sangamo Therapeutics, Inc. · Granted Tue Dec 10 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 05 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  34. US 10500246

    Compositions for delivery to and treatment of atherosclerotic plaques

    SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE · Granted Tue Dec 10 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 05 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  35. US 10500256

    Polymers for delivery of therapeutic proteins

    The Board of Regents of the University of Texas System · Granted Tue Dec 10 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 05 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  36. US 10500271

    Compositions and methods for self-adjuvanting vaccines against microbes and tumors

    The Regents of the University of California · Granted Tue Dec 10 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 05 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  37. US 10500262

    Synthetic antigen constructs against Campylobacter jejuni

    United States of America as represented by the Secretary of the Air Force · Granted Tue Dec 10 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 05 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  38. US 10500269

    Human rotavirus vaccine strains and diagnostics

    The United States of America, as represented by the Secretary, Department of Health and Human Services · Granted Tue Dec 10 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 05 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  39. US 10500290

    Peptide reagents and methods for detection and targeting of dysplasia, early cancer and cancer

    THE REGENTS OF THE UNIVERSITY OF MICHIGAN · Granted Tue Dec 10 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 05 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  40. US 10501435

    Substituted quinazoline compounds and uses thereof for modulating glucocerebrosidase activity

    Northwestern University · Granted Tue Dec 10 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 05 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  41. US 10500281

    Injectable long-acting local anesthetic semi-solid formulations and its compositions

    MIRA PHARMA CORPORATION · Granted Tue Dec 10 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 05 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  42. US 10501428

    Thymoquinone derivatives for treatment of cancer

    UNITED ARAB EMIRATES UNIVERSITY · Granted Tue Dec 10 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 05 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  43. US 10501439

    DNA-PK inhibitors

    Vertex Pharmaceuticals Incorporated · Granted Tue Dec 10 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 05 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  44. US 10501482

    Compounds for treating spinal muscular atrophy

    PTC THERAPEUTICS, INC. · Granted Tue Dec 10 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 05 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  45. US 10501470

    Use of asarinin in preparation of medicines for treating various coughs

    THE FIRST AFFILIATED HOSPITAL OF GUANGZHOU MEDICAL UNIVERSITY · Granted Tue Dec 10 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 05 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  46. US 10501504

    Adhesin as immunogen against enterotoxigenic Escherichia coli

    United States of America as represented by the Secretary of the Air Force · Granted Tue Dec 10 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 05 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  47. US 10501490

    Taccalonolide microtubule stabilizers

    The Board of Regents of the University of Texas System · Granted Tue Dec 10 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 05 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  48. US 10501500

    Methods of detection and removal of rhabdoviruses from cell lines

    Takeda Vaccines, Inc. · Granted Tue Dec 10 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 05 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

Frequently asked questions

How many pharma patents expire in 2039?

1,782 published patents in our USPTO index have expiration dates falling in calendar year 2039.