Wednesday, June 10, 2026

Intelligence · Patents

Patents expiring in 2039

Annual patent cliff calendar for 2039 — US pharmaceutical patents by expiration date.

Patents
1,782

Quick answer

1,782 indexed pharmaceutical patents have expiration dates in 2039. Browse by soonest expiry with links to assignee companies and related drugs.

  1. US 10179155

    Phosphodiesterase-4 inhibiting phytochemical compositions

    Nature's Sunshine Products, Inc. · Granted Tue Jan 15 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 10 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  2. US 10179112

    Viral vector nanocapsule for targeting gene therapy and its preparation

    The Regents of the University of California · Granted Tue Jan 15 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 10 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  3. US 10179168

    HPV particles and uses thereof

    Aura Biosciences, Inc. · Granted Tue Jan 15 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 10 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  4. US 10179912

    RNA modulating oligonucleotides with improved characteristics for the treatment of duchenne and becker muscular dystrophy

    BIOMARIN TECHNOLOGIES B.V. · Granted Tue Jan 15 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 10 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  5. US 10179131

    Hepatitis B antiviral agents

    Enanta Pharmaceuticals, Inc. · Granted Tue Jan 15 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 10 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  6. US 10179114

    Phenolic coatings and methods of making and using same

    Northwestern University · Granted Tue Jan 15 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 10 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  7. US 10179142

    Treatment and/or prevention of bone metastasis

    Arizona Board of Regents on Behalf of the University of Arizona · Granted Tue Jan 15 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 10 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  8. US 10179151

    Methods of transdifferentiation and methods of use thereof

    TEL HASHOMER MEDICAL RESEARCH INFRASTRUCTURE AND SERVICES LTD. · Granted Tue Jan 15 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 10 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  9. US 10179119

    Method of treatment

    VANDA PHARMACEUTICALS INC. · Granted Tue Jan 15 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 10 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  10. US 10179173

    Semi-solid delivery systems

    Regents of the University of Minnesota · Granted Tue Jan 15 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 10 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  11. US 10179819

    Anti-PSMA antibodies, bispecific antigen-binding molecules that bind PSMA and CD3, and uses thereof

    REGENERON PHARMACEUTICALS, INC. · Granted Tue Jan 15 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 10 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  12. US 10179187

    Bioresorbable embolization microspheres

    Regents of the University of Minnesota · Granted Tue Jan 15 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 10 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  13. US 10182997

    Liposomal curcumin for treatment of cancer

    The Board of Regents of the University of Texas System · Granted Tue Jan 22 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 17 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  14. US 10183011

    Anti-depression compounds

    The Board of Regents of the University of Texas System · Granted Tue Jan 22 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 17 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  15. US 10183021

    sGC stimulators

    IRONWOOD PHARMACEUTICALS, INC. · Granted Tue Jan 22 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 17 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  16. US 10182994

    Nanoparticulate complex of nicotine and cerium oxide and use thereof

    The United States of America, as represented by the Secretary, Department of Health and Human Services · Granted Tue Jan 22 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 17 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  17. US 10183055

    Ang-(1-7) derivative oligopeptides for the treatment of pain and other indications

    Arizona Board of Regents on Behalf of the University of Arizona · Granted Tue Jan 22 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 17 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  18. US 10182988

    Liposomal particles, methods of making same and uses thereof

    Northwestern University · Granted Tue Jan 22 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 17 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  19. US 10183915

    Axially chiral isomers, and preparation methods therefor and pharmaceutical uses thereof

    Medshine Discovery Inc. · Granted Tue Jan 22 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 17 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  20. US 10183942

    JAK kinase inhibitor compounds for treatment of respiratory disease

    Theravance Biopharma R&D IP, LLC · Granted Tue Jan 22 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 17 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  21. US 10183917

    Tricyclic compounds and uses thereof in medicine

    SUNSHINE LAKE PHARMA CO., LTD. · Granted Tue Jan 22 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 17 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  22. US 10184125

    Modulation of TMPRSS6 expression

    Ionis Pharmaceuticals, Inc. · Granted Tue Jan 22 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 17 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  23. US 10184124

    RNA interference in ocular indications

    Phio Pharmaceuticals Corp. · Granted Tue Jan 22 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 17 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  24. US 10183033

    Triptolide prodrugs

    Regents of the University of Minnesota · Granted Tue Jan 22 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 17 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  25. US 10184931

    Methods and systems for measuring and using the oxidation-reduction potential of a biological sample

    Aytu BioScience, Inc. · Granted Tue Jan 22 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 17 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  26. US 10183944

    Pyrimido-pyridazinone compounds and methods of use thereof

    Asana BioSciences, LLC · Granted Tue Jan 22 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 17 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  27. US 10183933

    Isoindolinone inhibitors of phosphatidylinositol 3-kinase

    Vertex Pharmaceuticals Incorporated · Granted Tue Jan 22 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 17 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  28. US 10183927

    Crystalline forms of C21H22Cl2N4O2

    Vertex Pharmaceuticals Incorporated · Granted Tue Jan 22 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 17 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  29. US 10183972

    BK channel-modulating peptides and their use

    The Board of Regents of the University of Texas System · Granted Tue Jan 22 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 17 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  30. US 10182984

    Targeted interferons demonstrate potent apoptotic and anti-tumor activities

    The Regents of the University of California · Granted Tue Jan 22 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 17 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  31. US 10184004

    CD47 targeted therapies for the treatment of infectious disease

    The United States of America, as represented by the Secretary, Department of Health and Human Services · Granted Tue Jan 22 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 17 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  32. US 10182979

    Biodegradable microspheres

    Regents of the University of Minnesota · Granted Tue Jan 22 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 17 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  33. US 10183936

    Hepatitis B core protein allosteric modulators

    ASSEMBLY BIOSCIENCES, INC. · Granted Tue Jan 22 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 17 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  34. US 10183080

    Use of single dendritic wedge cell penetrating peptides to facilitate cellular delivery of nanoparticles and nanoparticles carrying cargos

    The Government of the United States of America, as represented by the Secretary of the Navy · Granted Tue Jan 22 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 17 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  35. CA 3070264

    ASSOCIATIONS PHARMACEUTIQUES COMPRENANT UN ANTICORPS ANTI-BST-1 ET UN ANALOGUE DE CYTIDINE

    BERLIN CHEMIE AG [DE] · Granted Thu Jan 24 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Wed Jan 19 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  36. WO 2019016112

    COMPOSÉS DE QUINOLÉINE À SUBSTITUTION EN POSITIONS 1, 2, 3 ET 4 UTILISÉS EN TANT QUE MODULATEURS DE S1P

    ABBVIE DEUTSCHLAND [DE] · Granted Thu Jan 24 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Wed Jan 19 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  37. WO 2019016609

    TRAITEMENT DE LÉSIONS NON INFLAMMATOIRES

    ALLERGAN PHARMACEUTICALS INT LTD [IE] · Granted Thu Jan 24 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Wed Jan 19 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  38. US 10188739

    Compositions and methods for administering insulin or insulin-like protein to the brain

    XENETIC BIOSCIENCES, INC. · Granted Tue Jan 29 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 24 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  39. US 10188644

    Process of making stable abuse-deterrent oral formulations

    Collegium Pharmaceutical, Inc. · Granted Tue Jan 29 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 24 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  40. US 10188633

    Identification of small molecules that facilitate therapeutic exon skipping

    The Regents of the University of California · Granted Tue Jan 29 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 24 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  41. US 10188608

    Oxidized cellulose microspheres

    Covidien LP · Granted Tue Jan 29 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 24 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  42. US 10188461

    Selective fat removal using photothermal heating

    The Regents of the University of California · Granted Tue Jan 29 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 24 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  43. US 10188135

    Method for inducing satiety

    Stokely-Van Camp, Inc. · Granted Tue Jan 29 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 24 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  44. US 10189846

    Hepatitis B antiviral agents

    Enanta Pharmaceuticals, Inc. · Granted Tue Jan 29 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 24 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  45. US 10189784

    N-(5-((aryl or heteroaryl)methyloxy)pentyl)-substituted iminosugars as inhibitors of glucosylceramide synthase

    ACADEMISCH MEDISCH CENTRUM · Granted Tue Jan 29 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 24 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  46. US 10189952

    Degradable thiol-ene polymers

    The Regents of the University of Colorado, a body · Granted Tue Jan 29 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 24 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  47. US 10188619

    Solid solution compositions and use in chronic inflammation

    Infirst Healthcare Limited · Granted Tue Jan 29 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 24 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  48. US 10188614

    Particulate materials

    Nektar Therapeutics · Granted Tue Jan 29 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 24 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

Frequently asked questions

How many pharma patents expire in 2039?

1,782 published patents in our USPTO index have expiration dates falling in calendar year 2039.