Wednesday, June 10, 2026

Intelligence · Patents

Patents expiring in 2039

Annual patent cliff calendar for 2039 — US pharmaceutical patents by expiration date.

Patents
1,782

Quick answer

1,782 indexed pharmaceutical patents have expiration dates in 2039. Browse by soonest expiry with links to assignee companies and related drugs.

  1. US 10413565

    Nanostructures for modulating intercellular communication and uses thereof

    Northwestern University · Granted Tue Sep 17 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 12 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  2. EP 3539539

    TABLETTENFORMULIERUNGEN AUS (+)-2-[1-(3-ETHOXY-4-METHOXYPHENYL)-2-METHYLSULFONYLETHYL]-4-ACETYLAMINOISOINDOLIN-1,3-DION

    CELGENE CORP [US] · Granted Wed Sep 18 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Tue Sep 13 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  3. US 2019282668

    PTH Compounds with Low Peak-To-Trough Ratios

    ASCENDIS PHARMA BONE DISEASES AS [DK] · Granted Thu Sep 19 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Wed Sep 14 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  4. US 10420769

    Methods and compositions for inhibition of polymerase

    BioCryst Pharmaceuticals, Inc. · Granted Tue Sep 24 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 19 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  5. US 10422807

    Indirect homogeneous mobility shift assays for the detection of biologics in patient samples

    PRECISION IBD, INC. · Granted Tue Sep 24 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 19 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  6. US 10420747

    Cancer treatment method using ailanthone compounds

    EAST CHINA NORMAL UNIVERSITY · Granted Tue Sep 24 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 19 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  7. US 10420751

    Methods of treating inflammatory bowel disease with AMD3100 and tacrolimus

    MedRegen, LLC · Granted Tue Sep 24 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 19 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  8. US 10420758

    Indolinyl-sulfonamide inhibitors of tankyrase and methods of use thereof

    The Board of Regents of the University of Texas System · Granted Tue Sep 24 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 19 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  9. US 10420773

    Methods of treating developmental disorders and/or seizure disorders with etifoxine

    OVID THERAPEUTICS INC. · Granted Tue Sep 24 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 19 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  10. US 10420793

    Composition of novel carbohydrate drug for treatment of human diseases

    GALECTIN THERAPEUTICS, INC. · Granted Tue Sep 24 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 19 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  11. US 10420811

    Cultivation of selenium-rich Cyclocarya paliurus plant, extraction and use of active ingredients thereof

    INFINITUS (CHINA) COMPANY LTD. · Granted Tue Sep 24 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 19 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  12. US 10420832

    Synthetic peptide-based emergency vaccine against foot and mouth disease (FMD)

    United Biomedical, Inc. · Granted Tue Sep 24 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 19 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  13. US 10420812

    Drug combinations and uses in treating a coughing condition

    Infirst Healthcare Limited · Granted Tue Sep 24 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 19 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  14. US 10420813

    Competitive inhibitors of invariant chain expression and/or ectopic clip binding

    The Regents of the University of Colorado, a Body Corporate · Granted Tue Sep 24 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 19 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  15. US 10421798

    Factor VIII compositions and methods of making and using same

    BIOVERATIV THERAPEUTICS INC. · Granted Tue Sep 24 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 19 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  16. US 10420705

    Container assembly

    MEDISCA PHARMACEUTIQUE INC. · Granted Tue Sep 24 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 19 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  17. US 10420829

    Chlamydia vaccine

    The United States of America, as represented by the Secretary, Department of Health and Human Services · Granted Tue Sep 24 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 19 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  18. US 10422004

    Diagnostic method for distinguishing forms of esophageal eosinophilia

    The Regents of the University of California · Granted Tue Sep 24 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 19 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  19. US 10420918

    Compositions and methods for reducing traumatic edema of the central nervous system

    The Regents of the University of California · Granted Tue Sep 24 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 19 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  20. US 10421722

    Sulfur-containing compounds targeting vesicular acetylcholine transporter

    The Regents of the University of California · Granted Tue Sep 24 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 19 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  21. US 10420834

    Recombinant metapneumovirus F proteins and their use

    The United States of America, as represented by the Secretary, Department of Health and Human Services · Granted Tue Sep 24 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 19 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  22. US 10420851

    Stabilized radiolabeled anti-CD45 immunoglobulin compositions

    Actinium Phamaceuticals, Inc. · Granted Tue Sep 24 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 19 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  23. US 10421715

    Pleuromutilin derivative having 2-amino phenyl mercaptan side chain as well as preparation method and application thereof

    SOUTH CHINA AGRICULTURAL UNIVERSITY · Granted Tue Sep 24 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 19 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  24. US 10421752

    Compositions and methods for inhibition of the JAK pathway

    Rigel Pharmaceuticals, Inc. · Granted Tue Sep 24 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 19 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  25. US 10421773

    Bone-selective osteogenic oxysterol bisphosphonate analogs

    The Regents of the University of California · Granted Tue Sep 24 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 19 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  26. US 10421804

    Anti-Zika virus antibodies and methods of use

    REGENERON PHARMACEUTICALS, INC. · Granted Tue Sep 24 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 19 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  27. US 10421805

    Anti-hepatitis C antibodies and antigen binding fragments thereof

    United Kingdom Research and Innovation · Granted Tue Sep 24 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 19 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  28. US 10421838

    Methods for preparing polymeric reagents and compositions of polymeric reagents

    Nektar Therapeutics · Granted Tue Sep 24 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 19 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  29. US 10421980

    Methods and compositions for RNA-directed target DNA modification and for RNA-directed modulation of transcription

    The Regents of the University of California · Granted Tue Sep 24 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 19 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  30. US 10421964

    UNA oligomers and compositions for treating amyloidosis

    ARCTURUS THERAPEUTICS, INC. · Granted Tue Sep 24 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 19 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  31. US 10421945

    Agents and methods to elicit anti-tumor immune response

    The United States of America, as represented by the Secretary, Department of Health and Human Services · Granted Tue Sep 24 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 19 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  32. US 10421952

    Mutant organophosphorus acid anhydrolase enzymes having increased catalytic efficiency on V-agents

    The United States of America as represented by the Secretary of the Army · Granted Tue Sep 24 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 19 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  33. US 10421963

    Oligonucleotide therapy for leber congenital amaurosis

    ProQR Therapeutics II B.V. · Granted Tue Sep 24 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 19 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  34. US 10421813

    Oncostatin M receptor antigen binding proteins

    Kiniksa Pharmaceuticals, GmbH · Granted Tue Sep 24 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 19 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  35. US 10421802

    Human monoclonal antibodies against the middle east respiratory syndrome coronavirus (MERS-CoV) and engineered bispecific fusions with inhibitory peptides

    The United States of America, as represented by the Secretary, Department of Health and Human Services · Granted Tue Sep 24 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 19 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  36. US 10421765

    Tetrahydropyrido[4,3-d]pyrimidine inhibitors of ATR kinase

    The Board of Regents of the University of Texas System · Granted Tue Sep 24 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 19 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  37. US 10420833

    Combinatorial platform for the display of surface adjuvants and antigens

    The Board of Regents of the University of Texas System · Granted Tue Sep 24 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 19 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  38. US 10420799

    Processes for production of tumor infiltrating lymphocytes and uses of same in immunotherapy

    Iovance Biotherapeutics, Inc. · Granted Tue Sep 24 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 19 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  39. US 10420748

    Methods of treatment associated with the granulocyte colony-stimulating factor receptor

    Ligand Pharmaceuticals Incorporated · Granted Tue Sep 24 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 19 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  40. US 10420720

    Volatile anesthetic compositions comprising extractive solvents for regional anesthesia and/or pain relief

    The Board of Regents of the University of Texas System · Granted Tue Sep 24 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 19 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  41. WO 2019180199

    COMPOSITION AQUEUSE STABLE DE PHOSPHOCRÉATINE

    ALFASIGMA SPA [IT] · Granted Thu Sep 26 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Wed Sep 21 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  42. CA 3094934

    FORMULATIONS AQUEUSES STABLES D'ANTICORPS ANTI-TAU

    ABBVIE DEUTSCHLAND [DE] · Granted Thu Sep 26 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Wed Sep 21 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  43. US 10426839

    Pharmaceutical compositions comprising meloxicam

    AXSOME THERAPEUTICS, INC. · Granted Tue Oct 01 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 26 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  44. US 10426807

    Bone and joint protection composition and use thereof

    INFINITUS (CHINA) COMPANY LTD. · Granted Tue Oct 01 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 26 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  45. US 10426810

    Tangerine peel extract and its preparation and application

    INFINITUS (CHINA) COMPANY LTD. · Granted Tue Oct 01 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 26 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  46. US 10428008

    Nitroalkene non steroidal anti-inflammatory drugs (NA-NSAIDs) and methods of treating inflammation related conditions

    INSTITUT PASTEUR DE MONTEVIDEO · Granted Tue Oct 01 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 26 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  47. US 10426848

    Humanized FcγR mice

    REGENERON PHARMACEUTICALS, INC. · Granted Tue Oct 01 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 26 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  48. US 10428013

    Amide compound, preparation method and uses thereof

    China State Institute of Pharmaceutical Industry · Granted Tue Oct 01 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 26 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

Frequently asked questions

How many pharma patents expire in 2039?

1,782 published patents in our USPTO index have expiration dates falling in calendar year 2039.