Wednesday, June 10, 2026
🇺🇸 FDA

Intelligence · Patents

Patents expiring in 2039

Annual patent cliff calendar for 2039 — US pharmaceutical patents by expiration date.

Patents
1,782

Quick answer

1,782 indexed pharmaceutical patents have expiration dates in 2039. Browse by soonest expiry with links to assignee companies and related drugs.

  1. US 10370661

    Nucleic acid functionalized nanoparticles for therapeutic applications

    Northwestern University · Granted Tue Aug 06 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 01 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  2. US 10370656

    Nucleic acid functionalized nanoparticles for therapeutic applications

    Northwestern University · Granted Tue Aug 06 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 01 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  3. US 10370488

    Stimulus-responsive poly(lactic-co-glycolic)-based polymers and nanoparticles formed therefrom

    The Regents of the University of California · Granted Tue Aug 06 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 01 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  4. US 10370439

    Prevention of tissue ischemia and related methods

    The United States of America, as represented by the Secretary, Department of Health and Human Services · Granted Tue Aug 06 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 01 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  5. US 10370430

    Recombinant factor VIII proteins

    BIOVERATIV THERAPEUTICS INC. · Granted Tue Aug 06 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 01 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  6. US 10370380

    Octahydropyrrolo[3,4-c]pyrrole derivatives and uses thereof

    SUNSHINE LAKE PHARMA CO., LTD. · Granted Tue Aug 06 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 01 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  7. US 10370371

    Substituted pyrimidine Bmi-1 inhibitors

    PTC THERAPEUTICS, INC. · Granted Tue Aug 06 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 01 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  8. US 10370367

    IRAK inhibitors and method for making and using

    Rigel Pharmaceuticals, Inc. · Granted Tue Aug 06 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 01 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  9. US 10370419

    Tuberculosis vaccine compositions and related methods

    THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXTAS SYSTEM · Granted Tue Aug 06 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 01 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  10. US 10370357

    Method for producing sulfonyl chloride compound

    Takeda Pharmaceutical Company Limited · Granted Tue Aug 06 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 01 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  11. US 10370361

    Polymorphs and solid forms of a pyrimidinylamino-pyrazole compound, and methods of production

    DENALI THERAPEUTICS INC. · Granted Tue Aug 06 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 01 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  12. US 10370348

    Tocopherol and tocopheryl quinone derivatives as correctors of lysosomal storage disorders

    The United States of America, as represented by the Secretary, Department of Health and Human Services · Granted Tue Aug 06 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 01 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  13. US 10370349

    Functionalised benzopyran compounds and use thereof

    Kazia Therapeutics Limited · Granted Tue Aug 06 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 01 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  14. US 10370345

    Amyloid targeting agents and methods of using the same

    The Regents of the University of California · Granted Tue Aug 06 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 01 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  15. US 10369226

    Biodegradable lipids for the delivery of active agents

    Alnylam Pharmaceuticals, Inc. · Granted Tue Aug 06 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 01 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  16. US 10369232

    Allele selective gene editing and uses thereof

    ARCTURUS THERAPEUTICS, INC. · Granted Tue Aug 06 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 01 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  17. US 10369229

    Methods and compositions for liposomal formulation of antigens and uses thereof

    The Regents of the University of California · Granted Tue Aug 06 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 01 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  18. US 10369225

    Pharmaceutical compositions comprising meloxicam

    AXSOME THERAPEUTICS, INC. · Granted Tue Aug 06 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 01 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  19. US 10369208

    Methods for the induction of immune responses in a subject compromising administering virus-like particles (VLPS) prepared from Chikungunya virus structural proteins

    The United States of America, as represented by the Secretary, Department of Health and Human Services · Granted Tue Aug 06 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 01 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  20. US 10369182

    Compositions and methods for treating insomnia and other sleep related disorders

    Script Essentials, LLC · Granted Tue Aug 06 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 01 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  21. US 10369184

    Composition and use thereof in manufacture of product for improving intestinal function

    INFINITUS (CHINA) COMPANY LTD. · Granted Tue Aug 06 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 01 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  22. US 10369195

    Methods and compositions for preventing and treating damage to the heart

    The Regents of the University of California · Granted Tue Aug 06 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 01 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  23. US 10369145

    Coumarin derivatives and methods of use in treating hyperproliferative diseases

    DISCOVERYBIOMED, INC. · Granted Tue Aug 06 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 01 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  24. US 10369224

    Pharmaceutical compositions comprising meloxicam

    AXSOME THERAPEUTICS, INC. · Granted Tue Aug 06 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 01 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  25. US 10369142

    Combination dosage form of a mu opioid receptor antagonist and an opioid agent

    Theravance Biopharma R&D IP, LLC · Granted Tue Aug 06 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 01 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  26. US 10369148

    2,4-pyrimidinediamine compounds and their uses

    Rigel Pharmaceuticals, Inc. · Granted Tue Aug 06 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 01 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  27. US 10369118

    Method of reducing scarring

    Cole Research & Design, LLC · Granted Tue Aug 06 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 01 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  28. US 10369131

    Ultrapure tetrahydrocannabinol-11-oic acids

    Corbus Pharmaceuticals, Inc. · Granted Tue Aug 06 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 01 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  29. US 10369106

    Efficient aqueous encapsulation and controlled release of bioactive agents

    THE REGENTS OF THE UNIVERSITY OF MICHIGAN · Granted Tue Aug 06 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 01 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  30. US 10369103

    Neuroprotective liposome compositions and methods for treatment of stroke

    The Board of Regents of the University of Texas System · Granted Tue Aug 06 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 01 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  31. US 10368569

    Natural sweetener

    MONTERO GIDA SANAYI VE TICARET A.S. · Granted Tue Aug 06 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 01 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  32. US 10368543

    Pest control using natural pest control agent blends

    TYRATECH, INC. · Granted Tue Aug 06 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 01 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  33. US 10369098

    Methods for localized drug delivery

    Compass Therapeutics LLC · Granted Tue Aug 06 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 01 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  34. US 10369201

    Methods and compositions for treating Huntington's disease

    Sangamo Therapeutics, Inc. · Granted Tue Aug 06 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 01 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  35. US 10370679

    Modified immunization vectors

    ARIZONA BOARD OF REGENTS, A BODY CORPORATE OF THE STATE OF ARIZONA ACTING FOR AND ON BEHALF OF ARIZONA STATE UNIVERSITY · Granted Tue Aug 06 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 01 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  36. US 10370449

    Methods for treating skin infection by administering an IL-4R antagonist

    REGENERON PHARMACEUTICALS, INC. · Granted Tue Aug 06 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 01 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  37. US 10370366

    Pyridazinone compounds and methods for the treatment of cystic fibrosis

    Flatley Discovery Lab, LLC · Granted Tue Aug 06 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 01 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  38. US 10370360

    Small-molecule inhibitors targeting discoidin domain receptor 1 and uses thereof

    The Board of Regents of the University of Texas System · Granted Tue Aug 06 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 01 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  39. US 10370333

    Sulfonamide compounds and uses as TNAP inhibitors

    SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE · Granted Tue Aug 06 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 01 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  40. US 10369173

    Optimized methods for generation of cardiac stem cells from cardiac tissue and their use in cardiac therapy

    Capricor, Inc. · Granted Tue Aug 06 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 01 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  41. US 10369158

    Pharmaceutical packaging for estriol therapy

    The Regents of the University of California · Granted Tue Aug 06 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 01 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  42. US 10369141

    Methods of improving cell-based therapy

    The Regents of the University of California · Granted Tue Aug 06 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 01 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  43. MA 46343

    SCHÉMA POSOLOGIQUE POUR UN COMPOSÉ DE PTH À LIBÉRATION CONTRÔLÉE

    ASCENDIS PHARMA BONE DISEASES AS [DK] · Granted Wed Aug 07 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Tue Aug 02 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  44. US 10376489

    Wound healing

    The Regents of the University of California · Granted Tue Aug 13 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 08 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  45. US 10376495

    Small molecules that mimic or antagonize actions of granulocyte colony-stimulating-factor (G-CSF)

    The United States Government as Represented by the Department of Veterans · Granted Tue Aug 13 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 08 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  46. US 10376515

    Analogs of adenosine monophosphate (AMP) as inhibitors of ubiquitin-like modifier-activating enzyme ATG7

    Northwestern University · Granted Tue Aug 13 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 08 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  47. US 10376552

    Memory improving composition comprising arillus longan, semen nelumbinis, poria and semen juglandis

    INFINITUS (CHINA) COMPANY LTD. · Granted Tue Aug 13 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 08 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  48. US 10376525

    Treprostinil administration by inhalation

    United Therapeutics Corporation · Granted Tue Aug 13 2019 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 08 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

Frequently asked questions

How many pharma patents expire in 2039?

1,782 published patents in our USPTO index have expiration dates falling in calendar year 2039.

Drug approvals, clinical trials, M&A, event intelligence, and company updates — weekly.

Customize topics & region
Topics
Region

No spam. Unsubscribe anytime. See our privacy policy.