Wednesday, June 10, 2026
🇺🇸 FDA

Intelligence · Patents

Patents expiring in 2035

Annual patent cliff calendar for 2035 — US pharmaceutical patents by expiration date.

Patents
1,447

Quick answer

1,447 indexed pharmaceutical patents have expiration dates in 2035. Browse by soonest expiry with links to assignee companies and related drugs.

  1. US 9157069

    Method of producing pancreatic hormone-producing cells

    Takeda Pharmaceutical Company Limited · Granted Tue Oct 13 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 08 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  2. US 9161969

    Protection against influenza infection by granulocyte-macrophage colony stimulating factor

    The Board of Regents of the University of Texas System · Granted Tue Oct 20 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 15 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  3. US 9163258

    Method for the treatment of obesity

    The United States of America, as represented by the Secretary, Department of Health and Human Services · Granted Tue Oct 20 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 15 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  4. US 9161948

    Peptide oligonucleotide conjugates

    Sarepta Therapeutics, Inc. · Granted Tue Oct 20 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 15 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  5. US 9161995

    Methods and compositions for alteration of a cystic fibrosis transmembrane conductance regulator (CFTR) gene

    Sangamo Biosciences, Inc. · Granted Tue Oct 20 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 15 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  6. US 9161936

    Laquinimod for treatment of GABA mediated disorders

    TEVA PHARMACEUTICAL INDUSTRIES, LTD. · Granted Tue Oct 20 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 15 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  7. US 9161984

    Formulations and methods of use for alpha connexin C-terminal (ACT) peptides

    FIRSTSTRING RESEARCH, INC. · Granted Tue Oct 20 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 15 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  8. US 9162982

    4-[2-(2-fluorophenoxy methyl)phenyl]piperidine compounds

    Theravance Biopharma R&D IP, LLC · Granted Tue Oct 20 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 15 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  9. US 9163042

    Prodrugs of pyridone amides useful as modulators of sodium channels

    Vertex Pharmaceuticals Incorporated · Granted Tue Oct 20 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 15 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  10. US 9163248

    Targeting pseudotyped retroviral vectors

    The Regents of the University of California · Granted Tue Oct 20 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 15 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  11. US 9163236

    Pharmaceutical composition comprising NANOG SHRNA, and method of using NANOG SHRNA to treat cancer

    The United States of America as Represented by the Secretary, Dept. of Health and Human Services · Granted Tue Oct 20 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 15 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  12. US 9163244

    Suppressors of CpG oligonucleotides and methods of use

    The United States of America as Represented by the Secretary of the Department of Health and Human Services · Granted Tue Oct 20 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 15 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  13. US 9163215

    Generation of lineage-restricted progenitor cells from differentiated cells

    The Regents of the University of California · Granted Tue Oct 20 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 15 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  14. US 9163085

    Anti-OX40 antibodies and methods of treating cancer

    The Board of Regents of the University of Texas System · Granted Tue Oct 20 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 15 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  15. US 9163235

    Inhibitors of the miR-15 family of micro-RNAs

    MIRAGEN THERAPEUTICS, INC. · Granted Tue Oct 20 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 15 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  16. US 9162968

    Cyclohexane-1,3-diones for use in the treatment of amyotrophic lateral sclerosis

    Northwestern University · Granted Tue Oct 20 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 15 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  17. US 9161735

    Systems, compositions, and methods for local imaging and treatment of pain

    The Regents of the University of California · Granted Tue Oct 20 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 15 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  18. US 9161935

    Use of laquinimod for treating Crohn's disease patients who failed first-line anti-TNF therapy

    TEVA PHARMACEUTICAL INDUSTRIES, LTD. · Granted Tue Oct 20 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 15 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  19. US 9161990

    Hydrochloride salts of a glycopeptide-cephalosporin antbiotic compond

    THERAVANCE BIOPHARMA ANTIBIOTICS IP, LLC · Granted Tue Oct 20 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 15 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  20. US 9163245

    Compositions for linking zinc finger modules

    Sangamo Biosciences, Inc. · Granted Tue Oct 20 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 15 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  21. US 9163271

    Methods and compositions for the production of orthogonal tRNA-aminoacyl tRNA synthetase pairs

    The Regents of the University of California · Granted Tue Oct 20 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 15 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  22. US 9162980

    Anti-depression compounds

    The Board of Regents of the University of Texas System · Granted Tue Oct 20 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 15 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  23. US 9163022

    Tricyclic compounds as modulators of TNF-α synthesis and as PDE4 inhibitors

    VTV THERAPEUTICS LLC · Granted Tue Oct 20 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 15 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  24. US 9163068

    Influenza virus recombinant proteins

    The United States of America as Represented by The Secretary of the Department of Health and Human Services National Institutes of Health Office of Technology Transfer · Granted Tue Oct 20 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 15 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  25. US 9162989

    2,4-Pyrimidinediamine compounds and their uses

    Rigel Pharmaceuticals, Inc. · Granted Tue Oct 20 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 15 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  26. US 9168227

    Multi-encapsulated microspheres made with oxidized cellulose for in-situ reactions

    Covidien LP · Granted Tue Oct 27 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 22 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  27. US 9168262

    Estriol therapy for multiple sclerosis and other autoimmune diseases

    The Regents of the University of California · Granted Tue Oct 27 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 22 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  28. US 9169238

    Solid pharmaceutical composition

    Takeda Pharmaceutical Company Limited · Granted Tue Oct 27 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 22 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  29. US 9168297

    Regulation of skin pigmentation by neuregulin-1 (NRG-1)

    The United States of America, as represented by the Secretary, Department of Health and Human Services · Granted Tue Oct 27 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 22 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  30. US 9168311

    Oligomer-dantrolene conjugates and related compounds

    Nektar Therapeutics · Granted Tue Oct 27 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 22 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  31. US 9169182

    Chrysophaentin analogs that inhibit FtsZ protein

    The United States of America, as represented by the Secretary, Department of Health and Human Services · Granted Tue Oct 27 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 22 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  32. US 9169249

    Protein kinase C inhibitors and uses thereof

    Rigel Pharmaceuticals, Inc. · Granted Tue Oct 27 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 22 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  33. US 9169296

    Expression and assembly of human group C rotavirus-like particles and uses thereof

    The United States of America, as represented by the Secretary, Department of Health and Human Services · Granted Tue Oct 27 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 22 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  34. US 9169294

    Anti-angiogenic molecules, nanostructures and uses thereof

    Northwestern University · Granted Tue Oct 27 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 22 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  35. US 9169354

    Multifunctional forms of polyoxazoline copolymers and drug compositions comprising the same

    Serina Therapeutics, Inc. · Granted Tue Oct 27 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 22 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  36. US 9169303

    Vault compositions for immunization

    The Regents of the University of California · Granted Tue Oct 27 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 22 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  37. US 9169313

    Method of treatment of cancers characterized by ligand-dependent activating mutations in FGFR2 with FGFR1 ECD proteins

    Five Prime Therapeutics, Inc. · Granted Tue Oct 27 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 22 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  38. US 9169321

    Activatable binding polypeptides and methods of identification and use thereof

    The Regents of the University of California · Granted Tue Oct 27 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 22 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  39. US 9168266

    Hybrid diazeniumdiolated compounds, pharmaceutical compositions, and method of treating cancer

    The United States of America, as represented by the Secretary, Department of Health and Human Services · Granted Tue Oct 27 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 22 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  40. US 9168261

    Compositions and methods for cartilage repair

    REGENERATIVE SCIENCES, LLC · Granted Tue Oct 27 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 22 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  41. US 9168269

    Inhibitors of long and very long chain fatty acid metabolism as broad spectrum anti-virals

    THE TRUSTEES OF PRINCETON UNIVERSITY · Granted Tue Oct 27 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 22 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  42. US 9169326

    Recombinant monoclonal antibodies and corresponding antigens for colon and pancreatic cancers

    PRECISION BIOLOGICS, INC. · Granted Tue Oct 27 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 22 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  43. US 9167841

    Tangerine peel extract and its preparation and application

    INFINITUS (CHINA) COMPANY LTD. · Granted Tue Oct 27 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 22 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  44. US 9168291

    β-mannosylceramide and stimulation of NKT cell anti-tumor immunity

    The United States of America, as represented by the Secretary, Department of Health and Human Services · Granted Tue Oct 27 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 22 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  45. US 9169350

    N-maleimidyl polymer derivatives

    Nektar Therapeutics · Granted Tue Oct 27 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 22 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  46. US 9169297

    Subgenomic replicons of the flavivirus dengue

    The United States of America, as represented by the Secretary, Department of Health and Human Services · Granted Tue Oct 27 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 22 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  47. US 9169280

    Methods for the synthesis of plasmalogens and plasmalogen derivatives, and therapeutic uses thereof

    Phenomenome Discoveries Inc. · Granted Tue Oct 27 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 22 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  48. US 9169495

    Targeted gene delivery to non-phagocytic mammalian cells via bacterially derived intact minicells

    EnGeneIC Molecular Delivery Pty Ltd · Granted Tue Oct 27 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 22 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

Frequently asked questions

How many pharma patents expire in 2035?

1,447 published patents in our USPTO index have expiration dates falling in calendar year 2035.

Drug approvals, clinical trials, M&A, event intelligence, and company updates — weekly.

Customize topics & region
Topics
Region

No spam. Unsubscribe anytime. See our privacy policy.