Wednesday, June 10, 2026

Intelligence · Patents

Patents expiring in 2035

Annual patent cliff calendar for 2035 — US pharmaceutical patents by expiration date.

Patents
1,447

Quick answer

1,447 indexed pharmaceutical patents have expiration dates in 2035. Browse by soonest expiry with links to assignee companies and related drugs.

  1. US 9216198

    Compositions and medical devices for controlled release of nitric oxide and methods of production thereof

    The Board of Regents of the University of Texas System · Granted Tue Dec 22 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 17 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  2. US 9216214

    Replication-competent adenoviral vectors

    The United States of America as Represented by the Secretary of the Department of Health and Human Services · Granted Tue Dec 22 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 17 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  3. ZA 201308176

    THERAPEUTIC TREATMENT

    ASTRAZENECA AB [SE] · Granted Wed Dec 23 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Tue Dec 18 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  4. US 2015366947

    A Method of Purifying Therapeutic Proteins

    CSL LTD [AU] · Granted Thu Dec 24 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Wed Dec 19 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  5. US 9221836

    Heterocyclic compound and use thereof

    Takeda Pharmaceutical Company Limited · Granted Tue Dec 29 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 24 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  6. US 9221763

    Process for preparing biphenyl imidazole compounds

    Theravance Biopharma R&D IP, LLC · Granted Tue Dec 29 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 24 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  7. US 9220737

    Plant cell culture expressing human lysosomal proteins and uses thereof

    Protalix Ltd. · Granted Tue Dec 29 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 24 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  8. US 9220730

    Methods of treating ischemic spasticity

    The Regents of the University of California · Granted Tue Dec 29 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 24 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  9. US 9220729

    Ameliorating nervous systems disorders

    The Regents of the University of California · Granted Tue Dec 29 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 24 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  10. US 9220722

    Microrna (miRNA) and downstream targets for diagnostic and therapeutic purposes

    Julius-Maximilians-Universitat Wurzburg · Granted Tue Dec 29 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 24 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  11. US 9220692

    Methods of reducing symptoms in subjects using single dosage forms with tapering release rates

    TEVA WOMEN'S HEALTH, INC. · Granted Tue Dec 29 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 24 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  12. US 9220685

    Hollow silica nanospheres and methods of making same

    The Regents of the University of California · Granted Tue Dec 29 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 24 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  13. US 9220683

    Lipids and compositions for the delivery of therapeutics

    Tekmira Pharmaceuticals Corporation · Granted Tue Dec 29 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 24 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  14. US 9220676

    Injectable in-situ crosslinked hydrogel and methods of making and using thereof

    BIOREGEN BIOMEDICAL (CHANGZHOU) CO., LTD. · Granted Tue Dec 29 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 24 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  15. US 9220261

    Volatile blends and the effects thereof on the navel orangeworm moth

    The United States of America, as represented by the Secretary of Agriculture · Granted Tue Dec 29 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 24 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  16. US 9221792

    N-(4-(azetidine-1-carbonyl) phenyl)-(hetero-) arylsulfonamide derivatives as pyruvate kinase M2 (PMK2) modulators

    Agios Pharmaceuticals, Inc. · Granted Tue Dec 29 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 24 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  17. US 9221838

    Inhibitors of AKT activity

    ALMAC DISCOVERY LIMITED · Granted Tue Dec 29 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 24 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  18. US 9221843

    Heteroaryl inhibitors of PDE4

    Tetra Discovery Partners · Granted Tue Dec 29 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 24 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  19. US 9222086

    Compositions and methods for silencing genes expressed in cancer

    The United States of America, as represented by the Secretary, Department of Health and Human Services · Granted Tue Dec 29 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 24 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  20. US 9222091

    Therapeutic compositions

    Alnylam Pharmaceuticals, Inc. · Granted Tue Dec 29 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 24 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  21. US 9222142

    Adenoviruses and their use

    The United States of America as Represented by the Secretary of the Department of Health and Human Services · Granted Tue Dec 29 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 24 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  22. US 9221878

    Cyclosporin analogues for preventing or treating hepatitis C infection

    Enanta Pharmaceuticals, Inc. · Granted Tue Dec 29 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 24 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  23. US 9221772

    Synthesis of syrbactin proteasome inhibitors

    The Regents of the University of California · Granted Tue Dec 29 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 24 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  24. US 9221858

    Sialic acid analogs

    Ultragenyx Pharmaceutical Inc. · Granted Tue Dec 29 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 24 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  25. US 9220748

    Macrocyclic proline derived HCV serine protease inhibitors

    Enanta Pharmaceuticals, Inc. · Granted Tue Dec 29 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 24 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  26. US 9220735

    Methods of using krill oil to treat risk factors for cardiovascular, metabolic, and inflammatory disorders

    AKER BIOMARINE ANTARCTIC AS · Granted Tue Dec 29 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 24 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  27. US 9220733

    Solubilization of antigen components for removal from tissues

    The Regents of the University of California · Granted Tue Dec 29 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 24 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  28. US 9220706

    Inhibition of leukemic stem cells by PP2A activating agents

    THE UNITED STATES OF AMERICA NIH DIVISION OF EXTRAMURAL INVENTIONS AND TECHNOLOGY RESOURCES (DEITR) · Granted Tue Dec 29 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 24 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  29. US 9221800

    Isoxazole treatments for diabetes

    The Board of Regents of the University of Texas System · Granted Tue Dec 29 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 24 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  30. US 9221840

    Treating protein folding disorders with small molecule CFTR correctors

    DISCOVERYBIOMED, INC. · Granted Tue Dec 29 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 24 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  31. US 9220772

    Anti-tumor antigen antibodies and methods of use

    The Regents of the University of California · Granted Tue Dec 29 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 24 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  32. EP 2958945

    KOMBINATIONSTHERAPIE MIT ANTIKÖRPERN GEGEN CLAUDIN 18.2 ZUR BEHANDLUNG VON KREBS

    GANYMED PHARMACEUTICALS AG [DE] · Granted Wed Dec 30 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Tue Dec 25 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  33. US 9228188

    Compositions and method for inhibiting hepcidin antimicrobial peptide (HAMP) or HAMP-related gene expression

    Alnylam Pharmaceuticals, Inc. · Granted Tue Jan 05 2016 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 31 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  34. US 9226919

    Methods for dosing an orally active 1,2,4-oxadiazole

    PTC THERAPEUTICS, INC. · Granted Tue Jan 05 2016 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 31 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  35. US 9228172

    Inducible regulatory T-cell generation for hematopoietic transplants

    Regents of the University of Minnesota · Granted Tue Jan 05 2016 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 31 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  36. US 9228014

    Antibodies capable of blocking the interaction between CD48 and a CD48 receptor

    REGENERON PHARMACEUTICALS, INC. · Granted Tue Jan 05 2016 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 31 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  37. US 9226970

    Oligomer modified diaromatic substituted compounds

    Nektar Therapeutics · Granted Tue Jan 05 2016 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 31 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  38. US 9226910

    Treatment for obesity

    Jazz Pharmaceuticals International III Limited · Granted Tue Jan 05 2016 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 31 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  39. US 9226896

    Crystalline freebase forms of a biphenyl compound

    Theravance Biopharma R&D IP, LLC · Granted Tue Jan 05 2016 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 31 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  40. US 9227918

    Short acting phenylalkylamine calcium channel blockers and uses thereof

    Milestone Pharmaceuticals Inc. · Granted Tue Jan 05 2016 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 31 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  41. US 9226969

    Salt form of a multi-arm polymer-drug conjugate

    Nektar Therapeutics · Granted Tue Jan 05 2016 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 31 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  42. US 9226930

    1,2,4-triazolo [4,3-a] pyridine derivatives and their use for the treatment of prevention of neurological and psychiatric disorders

    Addex Pharma, S.A. · Granted Tue Jan 05 2016 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 31 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  43. US 9226955

    Allogeneic autophagosome-enriched composition for the treatment of disease

    Providence Health & Services—Oregon · Granted Tue Jan 05 2016 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 31 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  44. US 9226921

    Fused heterocyclic compounds as phosphodiesterases (PDES) inhibitors

    Takeda Pharmaceutical Company Limited · Granted Tue Jan 05 2016 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 31 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  45. US 9226881

    Multi-functional composite powder

    JGC Catalysts and Chemicals Ltd. · Granted Tue Jan 05 2016 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 31 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  46. US 9226937

    Compositions containing resveratrol and nucleotides

    RESVERATROL PARTNERS, LLC · Granted Tue Jan 05 2016 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 31 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  47. US 9228001

    Mutants of cholesterol-dependent cytolysins and uses thereof

    The Board of Regents of the University of Oklahoma · Granted Tue Jan 05 2016 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 31 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  48. US 9227044

    Applicator for applying a fluid to a surface

    AMNEAL PHARMACEUTICALS LLC · Granted Tue Jan 05 2016 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 31 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

Frequently asked questions

How many pharma patents expire in 2035?

1,447 published patents in our USPTO index have expiration dates falling in calendar year 2035.