Wednesday, June 10, 2026

Intelligence · Patents

Patents expiring in 2035

Annual patent cliff calendar for 2035 — US pharmaceutical patents by expiration date.

Patents
1,447

Quick answer

1,447 indexed pharmaceutical patents have expiration dates in 2035. Browse by soonest expiry with links to assignee companies and related drugs.

  1. US 9127021

    Hepatitis C virus inhibitors

    Enanta Pharmaceuticals, Inc. · Granted Tue Sep 08 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 03 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  2. US 9127027

    Epoxyeicosatrienoic acid analogs and methods of making and using the same

    The Board of Regents of the University of Texas System · Granted Tue Sep 08 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 03 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  3. US 9127050

    Multicomponent immunogenic composition for the prevention of beta-hemolytic streptococcal (BHS) disease

    Regents of the University of Minnesota · Granted Tue Sep 08 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 03 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  4. US 9127056

    Monospecific and bispecific human monoclonal antibodies targeting insulin-like growth factor II (IGF-II)

    The United States of America, as represented by the Secretary, Department of Health and Human Services · Granted Tue Sep 08 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 03 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  5. US 9127057

    Anti-IL-23 heterodimer specific antibodies

    TEVA PHARMACEUTICALS AUSTRALIA PTY LTD · Granted Tue Sep 08 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 03 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  6. US 9127068

    Nucleic acids encoding human glucagon receptor antibodies

    REGENERON PHARMACEUTICALS, INC. · Granted Tue Sep 08 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 03 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  7. US 9127292

    Non-human animals having a humanized signal-regulatory protein gene

    REGENERON PHARMACEUTICALS, INC. · Granted Tue Sep 08 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 03 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  8. US 9127274

    Serpinc1 iRNA compositions and methods of use thereof

    Alnylam Pharmaceuticals, Inc. · Granted Tue Sep 08 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 03 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  9. US 9128093

    Selective cytopheresis devices and related methods thereof

    THE REGENTS OF THE UNIVERSITY OF MICHIGAN · Granted Tue Sep 08 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 03 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  10. US 9132192

    Anti-EGFR antibodies and uses thereof

    REGENERON PHARMACEUTICALS, INC. · Granted Tue Sep 15 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 10 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  11. US 9132152

    Compositions and methods for generating induced pluripotent stem cells

    The Regents of the University of California · Granted Tue Sep 15 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 10 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  12. US 9132135

    Method of treating organophosphorous poisoning

    The United States of America as represented by the Secretary of the Army · Granted Tue Sep 15 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 10 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  13. US 9132174

    Treatment of heart disease by inhibition of the action of ribosomal S6 kinase 3 (RSK3)

    Anchored RSK3 Inhibitors, LLC · Granted Tue Sep 15 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 10 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  14. US 9132122

    1′,3′-disubstituted-4-phenyl-3,4,5,6-tetrahydro-2H,1′H-[1,4′]bipyridinyl-2′-ones

    Addex Pharma, S.A. · Granted Tue Sep 15 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 10 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  15. US 9133200

    Imidazo[1,2-b]pyridazine and imidazo[4,5-b]pyridine derivatives as JAK inhibitors

    Almirall, S.A. · Granted Tue Sep 15 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 10 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  16. US 9133259

    Cartilage oligomeric matrix protein (COMP)—growth factor complexes and uses thereof

    The Regents of the University of California · Granted Tue Sep 15 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 10 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  17. US 9132200

    Oligomer-calcium channel blocker conjugates

    Nektar Therapeutics · Granted Tue Sep 15 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 10 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  18. US 9133480

    Recombinant modified vaccinia ankara (MVA) vaccinia virus containing restructured insertion sites

    The United States of America, as represented by the Secretary, Department of Health and Human Services · Granted Tue Sep 15 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 10 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  19. US 9132087

    Auris formulations for treating otic diseases and conditions

    The Regents of the University of California · Granted Tue Sep 15 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 10 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  20. US 9132201

    Hydrogels based on polymers of dextran tyramine and tyramine conjugates of natural polymers

    UNIVERSITY OF TWENTE, INSTITUTE FOR BIOMEDICAL AND TECHNICAL MEDICINE (MIRA) · Granted Tue Sep 15 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 10 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  21. US 9133133

    2,4-pyridinediamine compounds and their uses

    Rigel Pharmaceuticals, Inc. · Granted Tue Sep 15 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 10 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  22. US 9133478

    Modified vaccinia Ankara (MVA) virus recombinants comprising heterologous coding sequences inserted into the intergenic regions between essential genes

    The United States of America, as represented by the Secretary, Department of Health and Human Services · Granted Tue Sep 15 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 10 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  23. US 9132096

    Abuse resistant pharmaceutical compositions

    REKHI GURVINDER SINGH [US] · Granted Tue Sep 15 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 10 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  24. US 9132138

    Method for the treatment of multiple sclerosis

    CASI Pharmaceuticals, Inc · Granted Tue Sep 15 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 10 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  25. US 9133462

    dsRNA for treating viral infection

    Arrowhead Research Corporation · Granted Tue Sep 15 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 10 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  26. US 9133454

    Method and medicament for inhibiting the expression of a given gene

    Alnylam Pharmaceuticals, Inc. · Granted Tue Sep 15 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 10 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  27. US 9133461

    Compositions and methods for inhibiting expression of the ALAS1 gene

    Alnylam Pharmaceuticals, Inc. · Granted Tue Sep 15 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 10 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  28. US 9133250

    Proteins with repetitive bacterial-Ig-like (Big) domains present in Leptospira species

    THE UNITED STATES OF AMERICA REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS · Granted Tue Sep 15 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 10 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  29. US 9133253

    Ricin vaccine and methods of making thereof

    The United States of America as represented by the Secretary of the Army · Granted Tue Sep 15 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 10 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  30. US 9133162

    Substituted quinoline compounds and methods of use

    SUNSHINE LAKE PHARMA CO., LTD. · Granted Tue Sep 15 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 10 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  31. US 9133129

    Bicyclic compound

    Takeda Pharmaceutical Company Limited · Granted Tue Sep 15 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 10 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  32. US 9133127

    Cannabinoid receptor antagonists/inverse agonists useful for treating disease conditions, including metabolic disorders and cancers

    Jenrin Discovery, LLC · Granted Tue Sep 15 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 10 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  33. US 9132210

    Scaffolds for cell transplantation

    THE REGENTS OF THE UNIVERSITY OF MICHIGAN · Granted Tue Sep 15 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 10 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  34. US 9132107

    Gamma-hydroxybutyrate compositions and their use for the treatment of disorders

    Jazz Pharmaceuticals Ireland Limited · Granted Tue Sep 15 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 10 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  35. US 9138432

    Methods for the administration of iloperidone

    VANDA PHARMACEUTICALS INC. · Granted Tue Sep 22 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 17 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  36. US 9138386

    Dental whitening compositions

    DISCUS DENTAL, LLC · Granted Tue Sep 22 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 17 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  37. US 9138404

    Treating critically ill patients with intravenous ibuprofen

    Cumberland Pharmaceuticals Inc. · Granted Tue Sep 22 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 17 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  38. US 9138383

    Nanogel materials and methods of use thereof

    The Regents of the University of Colorado, a Body Corporate · Granted Tue Sep 22 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 17 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  39. US 9139529

    Substituted quinoxalines as sodium channel modulators

    Vertex Pharmaceuticals Incorporated · Granted Tue Sep 22 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 17 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  40. US 9138416

    Sustained-release nanoparticle compositions and methods using the same

    Board of Regents of the University of Nebraska by and behalf of the University of Nebraska Medical Center · Granted Tue Sep 22 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 17 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  41. US 9138387

    Oral composition for removing tooth stain

    Regenetiss, Inc. · Granted Tue Sep 22 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 17 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  42. US 9138479

    Formulations for the treatment of diabetes

    XERIS PHARMACEUTICALS, INC. · Granted Tue Sep 22 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 17 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  43. US 9139530

    Solid forms of N-[2,4-bis(1,1-dimethylethyl)-5-hydroxyphenyl]-1,4-dihydro-4-oxoquinoline-3-carboxamide

    Vertex Pharmaceuticals Incorporated · Granted Tue Sep 22 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 17 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  44. US 9139634

    Interferon-antibody fusion proteins demonstrating potent apoptotic and anti-tumor activities

    The Regents of the University of California · Granted Tue Sep 22 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 17 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  45. US 9139833

    Modified small interfering RNA molecules and methods of use

    Arrowhead Research Corporation · Granted Tue Sep 22 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 17 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  46. US 9139644

    Modified chimeric polypeptides with improved pharmacokinetic properties

    REGENERON PHARMACEUTICALS, INC. · Granted Tue Sep 22 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 17 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  47. US 9140698

    Modulating bacterial MAM polypeptides in pathogenic disease

    The Board of Regents of the University of Texas System · Granted Tue Sep 22 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 17 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  48. US 9139834

    RNAi-related inhibition of TNF alpha signaling pathway for treatment of ocular angiogenesis

    Arrowhead Research Corporation · Granted Tue Sep 22 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 17 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

Frequently asked questions

How many pharma patents expire in 2035?

1,447 published patents in our USPTO index have expiration dates falling in calendar year 2035.